Metformin Canon ndi amodzi mwa othandizira odwala matenda ashuga omwe ali ndi mankhwala a metformin hydrochloride. Mankhwalawa amaphatikizidwa ndi gulu la biguanides a m'badwo wachitatu.
Kugwiritsa ntchito kwake ndikofunikira pakakhala vuto la glycemia osagwiritsa ntchito zakudya zoyenera komanso kuchita masewera olimbitsa thupi. Makamaka, mankhwalawa amathandiza odwala onenepa.
Kumbukirani kuti mankhwala aliwonse amakhala ndi zotsutsana ndipo amatha kukhala ndi zotsutsana ndi thupi. Chifukwa chake, musanagwiritse ntchito mankhwala aliwonse, muyenera kufunsa katswiri ndikuphunzira mosamala malangizo omwe aphatikizidwa.
Nkhaniyi ithandizira kudziwa mawonekedwe akugwiritsidwa ntchito ndi Metformin Canon, komanso mawonekedwe ake, malingaliro a akatswiri ndi odwala.
Zotsatira za mankhwala
Kuphatikizidwa kwa wothandizira antidiabetesic Metformin Canon kumaphatikizapo metformin hydrochloride, chinthu chodziwika bwino mdziko lapansi chomwe chitha kuchepetsa kuchuluka kwa shuga mukudwala matenda ashuga.
Kuphatikiza pa chinthu ichi, kukonzekera kumakhala ndi sodium stearyl fumarate, wowuma, titanium dioxide, talc, macrogol ndi zinthu zina.
Wopanga hypoglycemic wothandizira ndi kampani yopanga zamankhwala Canonfarm Production.
Kampaniyo imatulutsa mankhwala ofanana ndi mapiritsi (oyera, a biconvex) mu mitundu yosiyanasiyana:
- Metformin Canon 500 mg.
- Metformin Canon 850 mg.
- Metformin Canon 1000 mg.
Mankhwalawa amaloledwa kumwa kuchokera zaka 10, osati monotherapy, komanso jekeseni wa insulin. Mukamamwa, metformin imalowetsedwa m'matumbo, ndipo kuphatikiza kwakukulu kumachitika pafupifupi maola 2-2,5 pambuyo pakulowetsa. Machitidwe a hypoglycemic amawonetsedwa:
- kuletsa mapangidwe a glucose kuchokera osagwiritsa chakudya mu chiwindi;
- kufooketsa mayamwidwe am'magazi m'mimba;
- kukulitsa chiwopsezo cha minofu yolimbana ndi kuchepa kwa shuga;
- kuchotsa shuga m'matumbo;
- kulimbikitsa intracellular glycogeneis;
- kutsegula kwa glycogen synthase;
- kukhazikitsa lipid kagayidwe.
Kuphatikiza apo, mankhwalawa ali ndi mtundu wina wa fibrinolytic. Metformin Canon imatha kukhazikika ndikuchepetsa thupi. Amasiyana ndi kukonzekera kwa zotumphukira za sulfonylurea chifukwa sizimapangitsa kuphatikiza insulini ndipo sikuti kumayambitsa kuthamanga kwa shuga mwa anthu athanzi.
Gawo lolimbikira limafalikira mokwanira mu minofu. Itha kudzikundikira m'chiwindi, kumaso ndi impso.
Metformin siimapukusidwa, chifukwa chake imagwiridwa ndi impso mwanjira yosasintha.
Malangizo ogwiritsira ntchito mapiritsi
Ngakhale mutakambirana ndi adokotala mutagula mankhwalawo, malangizo ogwiritsira ntchito ayenera kuphunziridwa mosamala. Ngati muli ndi mafunso ndi wodwala, muyenera kufunsa uphungu.
Mapiritsi amalimbikitsidwa kwambiri kugwiritsa ntchito nthawi ya chakudya kapena itatha. Samasenda, koma kumeza ndi kapu yamadzi. Kufotokozera kwa mankhwalawa akuti mlingo woyambirira wa anthu akuluakulu ndi 1000-1500 mg patsiku. Pankhaniyi, ndikofunikira kugawa mlingo kangapo patsiku. Malangizowa akuchitika chifukwa chakuti pakusintha kwa thupi ndi zochita za metformin, zotsatira zoyipa zimachitika, makamaka zogwirizana ndi kugaya. Wodwala matenda a shuga amatha kudandaula za kusanza, kutsegula m'mimba, kusintha kwa kakomedwe, kupweteka m'mimba, komanso kugona. Komabe, patatha masiku 10 mpaka 14, izi zimangochitika zokha.
Thupi likazolowera metformin, dokotala amatha kuwonjezera kuchuluka kwa wothandizira wa hypoglycemic malinga ndi kuchuluka kwa shuga kwa wodwalayo. Mlingo wokonza umaganiziridwa kuti kuyambira 1500 mpaka 2000 mg patsiku. Mulingo wovomerezeka tsiku lililonse ndi 3000 mg.
Wodwalayo akatembenukira ku Metformin Canon ndi antipyretic ina, ayenera kusiya kuchita izi. Mukaphatikiza mankhwalawa ndi mankhwala a insulin, tikulimbikitsidwa kumayambiriro kwa mankhwalawa kumwa 500 kapena 850 mg kawiri kapena katatu patsiku. Metformin 1000 mg imatengedwa kamodzi patsiku.
Ana omwe afika zaka 10 akhoza kuyamba kulandira mankhwala ndi 500 mg ya mankhwalawa. Ndikofunika kuti muzidya nthawi yamadzulo mukamadya. Pambuyo masiku 10-14, adokotala amatha kuwonjezera kuchuluka kwa tsiku lililonse mpaka 1000-1500 mg. Mwanayo amaloledwa kutenga zosaposa 2000 mg patsiku.
Anthu odwala matenda ashuga ayenera kusamalidwa mwapadera. Mlingo ndi nthawi yayitali ya mankhwala amasankhidwa ndi dokotala payekhapayekha. Pazaka zopitilira 60, mankhwala a hypoglycemic angayambitse kusokonezeka kwa impso.
Dziwani kuti mankhwalawo sangagulidwe popanda mankhwala a dokotala. Ma CD a Metformin Canon amayenera kusungidwa ndi dzuwa kapena chinyezi. Kutentha kosungira sikuyenera kupitirira 25 digiri Celsius.
Pambuyo pa kumaliza ntchito, zomwe ndi zaka 2, kugwiritsa ntchito mankhwala antidiabetes kumaletsedwa.
Contraindication ndi zoyipa zosiyanasiyana
Metformin Canon silingagwiritsidwe ntchito ndi hypersensitivity kwa chophatikizira chopangira ndi zotulutsa. Kuphatikiza apo, sagwiritsidwa ntchito pakubereka komanso poyamwitsa. Izi zikufotokozedwa ndikuti wopanga sanachititse kafukufuku wokwanira kuti adziwe zotsatira za metformin mwa amayi apakati komanso oyembekezera. Chifukwa chake, pokonzekera kutenga pakati, mankhwala amaletsa. Ngati ndi kotheka, kugwiritsa ntchito mkaka wa mkaka ndioletsedwa.
Ponena za zaka za odwala, pali chimango china. Monga tanena kale, ndizoletsedwa kumwa mankhwalawa kwa ana osakwana zaka 10. Poganiziratu, Metformin Canon iyenera kugwiritsidwa ntchito kwa odwala omwe ali ndi zaka zopitilira 60, makamaka omwe akuchita ntchito yayikulu.
Malangizo omwe anaphatikizidwawa amaphatikiza ma pathologies ambiri ndi nthawi zomwe kugwiritsa ntchito mankhwala a hypoglycemic ndikotsutsana. Izi zikuphatikiza:
- Kukula kwa lactic acidosis.
- Poizoni woledzera.
- Uchidakwa wambiri
- Zakudya zamafuta ochepa, momwe amamwa zosakwana 1000 kcal patsiku.
- Zivulala zowopsa ndi mikwingwirima.
- Opaleshoni
- Kulephera kwina.
- Kukula kwa hypoxia.
- Matenda owopsa komanso osatha omwe amatha kuyambitsa hypoxia.
- Kutopa chifukwa cha kusanza, kutsegula m'mimba, kutentha thupi kapena matenda opweteka.
- Kuchepa kwa impso.
- Pachimake pathologies kuti azitaya chiwopsezo aimpso ntchito.
- Kukula kwa chikomokere, precoma, kapena matenda ashuga.
- Kugwiritsa ntchito mankhwala okhala ndi ayodini poyerekeza ndi radiology kapena radioisotope (masiku awiri asanafike komanso atatha).
Mwa zina zoyipa zomwe zimachitika chifukwa chosagwirizana ndi malamulo a kumwa mankhwala, titha kusiyanitsa:
- matenda am'mimba (makamaka amagwirizanitsidwa ndi kusintha kwa thupi ndi metformin);
- CNS chisokonezo - kusintha kwa kulawa (kukoma kwazitsulo mkamwa);
- chiwindi kukanika, kukula kwa chiwindi;
- zimachitika pakhungu - redness, kuyabwa, zidzolo, erythema (kawirikawiri);
- lactic acidosis;
- kuyamwa kwa vitamini B9;
- kusowa kwa vitamini B12.
Ndi mankhwala osokoneza bongo, chizungulire chimachitika, kuthamanga kwa chikumbumtima, kupweteka kwa minofu ndi m'mimba kumachitika, kutentha kwa thupi kumachepa, kugaya, mawonekedwe a lactic acidosis, amasokonezeka. Woopsa akayamba kudwala, pomwe wodwalayo amayenera kupita naye kuchipatala.
Njira yothandiza kwambiri yochotsa lactate owonjezera ndi hemodialysis, ndipo chithandizo chamankhwala chimachitidwanso.
Zochita zina zamankhwala
Monga mukudziwa, mankhwala ena amatha kukhala ndi vuto la Metformin Canon, kuchepetsa kapena kukulitsa mphamvu ya hypoglycemic.
Malangizowo akuti kuphatikiza komwe kumatsutsana ndikugwiritsa ntchito ayodini.
Potengera maziko a kulephera kwa impso kwa odwala, amatha kutsogolera kukula kwa lactic acidosis. Sipangonso kuphatikiza mowa, malupu okodzetsa ndi kukonzekera komwe kumakhala ndi ethanol ndi metformin.
Kuchenjera kwapadera kumafunika ndi mankhwala omwe amatha kufooketsa zochita za metformin ndikutsogolera ku hyperglycemia. Izi zikuphatikiza:
- Danazole
- Chlorpromazine.
- Ma antipsychotic.
- Glucocortecosteroids.
- Beta2-adrenergic agonists.
Angiotensin-akatembenuza enzyme zoletsa, ma insulin, ma salicylates, ma acarbose ndi zotumphukira za sulfonylureas zitha kupititsa patsogolo mphamvu ya hypoglycemic ya metformin.
Ndikofunikira kukumbukira kuti ngakhale mutatenga nifedipine ndi metformin, hypoglycemia imatha kuchitika m'mankhwala a shuga. Pofuna kupewa kukanika kwa impso, ndikofunikira kugwiritsa ntchito NSAIDs mosamala.
Mulimonsemo, posankha kugwiritsa ntchito mankhwala aliwonse, choyambirira, ndikofunikira kufunsa dokotala. Kubisika kwa ma pathologies kuchokera kwa dokotala kungayambitse zotsatira zosasintha.
Ndemanga ndi mitengo yamankhwala
Wodwala aliyense amapatsidwa mwayi wogula mankhwalawo ku pharmacy kapena kudzaza fomu yogula kudzera pa tsamba lovomerezeka la wopanga.
Wogula angathe kungoyang'ana pa chithandizo cha mankhwalawo, komanso mtengo wake. Tiyenera kudziwa kuti Metformin Canon ali ndi mtengo wotsika.
Chifukwa chake, wodwala aliyense amatha kugula mankhwala.
Mtengo wake umatengera mtundu wa kumasulidwa ndi kuchuluka kwa mapiritsi omwe ali phukusi:
- Metformin Canon 500 mg (mapiritsi 30) - kuchokera ku 94 mpaka 110 ma ruble;
- Metformin Canon 850 mg (mapiritsi 30) - 112 mpaka 116 zikwangwani;
- Metformin Canon 1000 mg (mapiritsi 30) - kuchokera ku 117 mpaka 165 rubles.
Pakati pa madokotala ndi odwala, mutha kupeza ndemanga zambiri zabwino pakugwiritsa ntchito mankhwalawa. Chifukwa chake, akatswiri a matenda ashuga akuti Metformin Canon amalimbitsa shuga popanda kuchititsa hypoglycemia. Ndemanga zimasonyezanso kuchepa kwa anthu onenepa kwambiri. Chifukwa chake, pakati pazabwino za mankhwalawa zimadziwika kuti ndizothandiza, kugwiritsa ntchito mosavuta komanso mtengo wotsika.
Zotsatira zoyipa za thupi zomwe zimachitika chifukwa cha zochita za metformin - kugaya chakudya m'mimba zimawerengedwa ngati mbali yoyipa yogwiritsa ntchito mankhwalawa. Koma pogawa Mlingo watsiku ndi tsiku Mlingo wangati womwewo, zizindikiro zotere zimachepa kwambiri.
Odwala ambiri omwe amamwa Metformin Canon amakumbutsanso kuti mankhwalawa amathandizidwa ngati "ayi" ngati simutsatira mankhwala, musamachite masewera olimbitsa thupi komanso osayang'anira shuga tsiku lililonse.
Mankhwala ofanana
Nthawi zina kugwiritsa ntchito mankhwalawa kumakhala kosatheka pazifukwa zosiyanasiyana, kaya ndi contraindication kapena zovuta zimachitika.
Zikatero, udindo wonse umakhala ndi dokotala, yemwe wasankha kusintha mankhwalawo. Pankhaniyi, ayenera kuganizira kuchuluka kwa shuga m'magazi a wodwalayo komanso mkhalidwe wake wathanzi.
Mankhwala omwewo ali ndi njira yofanana yothandizira, koma amasiyana pakapangidwe kake.
Metformin ndi mankhwala otchuka kwambiri omwe amagwiritsidwa ntchito polimbitsa shuga. Pankhaniyi, imagwiritsidwa ntchito ngati gawo logwira ntchito la othandizira ambiri a hypoglycemic.
Mwa ena odziwika a Metformin Canon kusiyanitsa:
- Gliformin ndi mankhwala othandizira odwala matenda ashuga omwe amagwiritsidwa ntchito poyambitsa sulfonylureas. Chifukwa cha metformin yomwe ilipo, imathandiza kuchepetsa kulemera kwa anthu omwe ali onenepa kwambiri. Mtengo wake wapakati umatengera mtundu wa kumasulidwa: ma ruble 500 mg -106, 850 mg -186 ndi 1000 mg - 368 rubles.
- Glucophage ndi njira ina yothanirana ndi gulu la Biguanide. Imakhalapo mwanjira yanthawi yayitali (Glucophage Long). Amagwiritsidwanso ntchito pa matenda a shuga omwe amadalira insulin. Mtengo wapakati wa phukusi limodzi umachokera ku 107 mpaka 315 rubles.
- Siofor 1000 ndi mankhwala omwe amagwiritsidwa ntchito kupewa komanso kuchiza matenda ashuga, komanso kuchepetsa kunenepa. Pafupipafupi, mtengo umasiyanasiyana kuchokera ku ma ruble 246 mpaka 420, chifukwa chake sungatchedwa analogue wotsika mtengo kwambiri.
- Metformin-Teva ndi mankhwala omwe amagwiritsidwa ntchito pa matenda a shuga a 2, pamene kudya ndi kuchita masewera olimbitsa thupi sizingathandize. Monga Metformin Canon, imakhazikika ndi glycemia, lipid metabolism, komanso kulemera kwamphamvu kwa thupi. Mtengo wapakati wamankhwala amachokera ku ruble 125 mpaka 260.
Pali mankhwala ena ambiri omwe ali ndi vuto lofanana ndi Metformin Canon. Zambiri zokhudzana ndi izi zimapezeka pogwiritsa ntchito intaneti kapena kufunsa dokotala.
Metformin Canon ndi mankhwala othandizira odwala matenda ashuga. Pogwiritsa ntchito moyenera, mutha kuchotsa zizindikiritso za "matenda okoma" ndikukhala ndi moyo wathanzi ndi anthu athanzi. Komabe, mukamagwiritsa ntchito mankhwalawa, muyenera kutsatira malangizo onse a dokotala, kuti musadzivulaze.
Katswiri kuchokera muvidiyoyi munkhaniyi ayankhula za Metformin.
