Lipoic acid ndi gulu lochita bwino lomwe kale linali m'gulu la mankhwala ofanana ndi vitamini. Pakadali pano, ofufuza ambiri amati mavitaminiwa ali ndi mankhwala.
Mu pharmacology, lipoic acid amatchedwanso lapamide, thioctic acid, para-aminobenzoic acid, alpha-lipoic acid, vitamini N ndi zipatso.
Mayina odziwika bwino apadziko lonse lapansi ndi thioctic acid.
Kutengera izi, makampani opanga mankhwala amapanga kukonzekera zamankhwala monga, mwachitsanzo, Berlition, Thioctacid ndi Lipoic acid.
Lipoic acid ndichinthu chofunikira kwambiri pakuphatikiza mafuta kagayidwe m'thupi. Ndi gawo lokwanira la chinthuchi mthupi la munthu, kuchuluka kwa cholesterol kumachepa.
Thioctic acid, yothandiza kutsitsa cholesterol yamagazi, imalepheretsa kukula kwa zovuta zomwe zimachitika chifukwa cha chitukuko cha matenda osokoneza bongo poyambira kunenepa kwambiri.
Kunenepa kwambiri nthawi zambiri kumakhala ndi mafuta ambiri. Lipoic acid wokhala ndi cholesterol amathandizira kuti achepetse, zomwe zimalepheretsa kukula kwa zovuta mu ntchito ya mtima, mtima ndi mantha.
Kukhalapo kwa gawo lokwanira la pulojekitiyi mthupi kumathandizira kuti masitepe asokere komanso kugunda kwa mtima, zikachitika, zimayendetsa bwino zotsatira za zovuta zotere.
Chifukwa cha kuphatikiza kowonjezereka kwa phula lathandizoli, kuchira kwathunthu kwamphamvu thupi ndikamachitika, ndipo kuchuluka kwa maresi ndi kuwonongeka kwa magwiridwe antchito ake ndi minyewa ya ubongo kumachepetsedwa kwambiri.
Zokhudza thupi za lipoic acid
Malinga ndi mawonekedwe akuthupi, lipoic acid ndi ufa wamakristali, womwe umakhala ndi mtundu wachikasu. Pulogalamuyi imakhala ndi zowawa komanso fungo linalake. Penti yamakristali imasungunuka pang'ono m'madzi ndipo imasungunuka bwino m'masamba. Mchere wa sodium wa lipoic acid umasungunuka bwino kwambiri m'madzi. Katunduyu wa mchere wa lipoic acid umayambitsa kugwiritsa ntchito pawiri, osati pureic wa asidi.
Pulogalamuyi imagwiritsidwa ntchito popanga mankhwala osiyanasiyana komanso zowonjezera zakudya.
Pulogalamuyi ili ndi mphamvu yotsutsa antioxidant m'thupi. Kudya kwa izi mthupi kumakupatsani mwayi wolimbitsa thupi moyenerera.
Chifukwa cha kukhalapo kwa antioxidant katundu, pawiri iyi imalimbikitsa kumanga ndi kuwachotsa kwa mitundu yosiyanasiyana ya mawonedwe aulere m'thupi. Vitamini N ali ndi kutanthauzira kumanga ndikumachotsa m'thupi la munthu zinthu zakupweteka ndi ma ion azitsulo zolemera.
Kuphatikiza apo, lipoic acid imathandizira kusintha magwiridwe antchito a chiwindi. Kuchuluka kwazomwe zimapangidwira m'thupi kumalepheretsa kukula kwa kuwonongeka kwa minyewa ya chiwindi pakachitika komanso kukula kwa matenda osachiritsika, monga hepatitis ndi cirrhosis.
Kukonzekera ndi lipoic acid pamapangidwe awo adanenanso katundu wa hepaprotective.
Zamoyo zosiyanasiyana za lipoic acid
Lipoic acid imatha kupereka insulin-monga, yomwe imalola kugwiritsa ntchito kukonzekera komwe kumapangidwira insulini m'malo mwa vuto la matenda a shuga m'thupi.
Chifukwa cha kupezeka kwa malowa, kukonzekera komwe kumakhala ndi vitamini N kumapangitsa kuti magawo azikhala ndi glucose cell ofunikira a thupi m'magawo oyamba a chitukuko cha matenda ashuga. Izi zimabweretsa kuchepa kwa shuga m'magazi a m'magazi. Kukonzekera, komwe kumaphatikizapo vitamini, kumatha kupititsa patsogolo ntchito ya insulin chifukwa cha kukhalapo kwa katundu wawo ndikuchotsa matenda omwe angathe kufa ndi shuga.
Vutoli limachitika pafupipafupi pakupanga matenda a shuga a 2 mthupi.
Chifukwa cha kuchuluka kwa zotumphukira kwa maselo am'magazi a glucose, njira zonse za metabolic m'maselo zimayamba kuchitika mwachangu kwambiri komanso mokwanira. Izi ndichifukwa choti glucose mu cell ndiye gwero lalikulu lamphamvu.
Chifukwa cha malo ake enieni, lipoic acid, makonzedwe okhala ndi piritsi iyi nthawi zambiri amagwiritsidwa ntchito pochiza matenda osagwirizana ndi insulin omwe amadalira shuga.
Chifukwa cha kusintha kwa magwiridwe antchito a ziwalo zosiyanasiyana, pamakhala kusintha kwamunthu.
Chifukwa cha kukhalapo kwa antioxidant katundu, phata imathandizira kubwezeretsa kapangidwe kake ndikugwira ntchito kwa minyewa yamitsempha.
Mukamagwiritsa ntchito pawiri iyi, kusintha kwamphamvu mthupi kumachitika.
Vitamini ndi metabolite wachilengedwe yemwe amapangidwa m'thupi la munthu ndikuthandizira kuti matupi awo azigwira ntchito komanso machitidwe awo.
Kudya kwa lipoic acid mthupi mokwanira kumathandiza kuchepetsa cholesterol mthupi.
Kudya kwa thioctic acid m'thupi la munthu
Munthawi yachilengedwe, gawo lochitira zabwinozi limalowa m'thupi la munthu kuchokera kuzakudya zomwe zili ndi zambiri zomwe zidali m'chipinda chino.
Kuphatikiza apo, chinthu chogwira ntchito ichi chimatha kupangidwa ndi thupi lokha, chifukwa chake cholic acid si imodzi mwazinthu zosakanikirika.
Tiyenera kudziwa kuti ndi zaka, komanso kuphwanya kwakukuru mthupi, kapangidwe kazinthu kameneka kamatha kuchepa kwambiri m'thupi. Izi zimabweretsa kuti munthu wodwala matenda ena amakakamizidwa kumwa mankhwala apadera kuti athe kulipirira kusowa kwa vitamini N m'thupi, zomwe zimapangitsa kuti pakhale kuchepa.
Njira yachiwiri yolipira kuchepa kwa vitamini ndikuwongolera chakudyacho kuti chitha kudya zakudya zambiri zomwe zili ndi mankhwala ambiri a lipoic acid. Kuchepetsa cholesterol m'thupi ndi matenda ashuga, tikulimbikitsidwa kugwiritsa ntchito kuchuluka kwa zakudya zomwe zili ndi mankhwala a lipoic acid. Izi zimachepetsa mwayi wokhala ndi zovuta komanso zimachepetsa kukula kwa kunenepa kwambiri, komwe ndi kuphatikizika kwa mtundu wa 2 shuga.
Lipoic acid amapezeka kuchuluka kwakukulu mu zakudya zotsatirazi:
- nthochi
- nyemba - nandolo, nyemba;
- nyama yanyama;
- ng'ombe chiwindi;
- bowa;
- yisiti
- mitundu iliyonse ya kabichi;
- amadyera - sipinachi, parsley, katsabola, basil;
- anyezi;
- mkaka ndi mkaka;
- impso
- mpunga
- tsabola;
- mtima
- mazira.
Zogulitsa zina zomwe sizinalembedwe mndandandawu zimaphatikizanso ndi bioactive pompo, koma zomwe zili zake ndizochepa kwambiri.
Kuchuluka kwa magwiridwe antchito amthupi la munthu kumaonedwa kuti 25-50 mg ya piritsi patsiku. Amayi oyembekezera komanso oyembekezera amayenera kudya alpha-lipoic acid pafupifupi 75 mg patsiku, ndipo ana osaposa zaka 15 kuyambira 12,5 mpaka 25 mg patsiku.
Pankhani ya kukhalapo kwa matenda a impso kapena a chiwindi cha mtima m'thupi la wodwalayo omwe amasokoneza momwe amagwirira ntchito, kuchuluka kwa mankhwalawa kumawonjezeka mpaka 75 mg patsiku la munthu wamkulu. Chizindikiro ichi sichikutengera zaka.
Izi ndichifukwa choti pakakhala zovuta pali kuwonongeka kwakanthawi kwa zinthu zofunikira m'thupi.
Kuchuluka komanso kuchepa kwa vitamini N m'thupi
Mpaka pano, zizindikiro zofotokozedwa bwino kapena zodziwika bwino za kuchepa kwa vitamini m'thupi sizinadziwikebe.
Izi ndichifukwa choti gawo ili la metabolism laumunthu limatha kupangidwa mwaokha mozungulira ndi maselo ndipo limakhalapo pafupipafupi.
Ndi kuchuluka kosakwanira kwa panganoli, zovuta zina zimatha kukhala m'thupi la munthu.
Zoyipa zazikulu zomwe zapezeka chifukwa cha kuchepa kwa lipoic acid ndi izi:
- Maonekedwe a pafupipafupi minyewa, yomwe imawoneka ngati chizungulire, ululu m'mutu, kukula kwa polyneuritis ndi matenda a shuga.
- Zosokoneza pakugwira ntchito kwa minyewa ya chiwindi, zomwe zimayambitsa kukula kwa mafuta a hepatosis ndi njira ya mapangidwe a bile.
- Kukula kwa atherosulinotic njira mu mtima.
- Kukula kwa metabolic acidosis.
- Maonekedwe a minofu kukokana.
- Kukula kwa myocardial dystrophy.
Vitamini N owonjezera m'thupi sichimachitika. Izi ndichifukwa choti chowonjezera chilichonse chomwe chimalowa m'thupi ndi zinthu kapena zinthu zina zofunikira pakudya chimachotsedwa msanga. Komanso, pakakhala kuchuluka kwa mavitamini, alibe nthawi yogwiritsa ntchito mphamvu yoyipa isanathe.
Nthawi zina, pamaso pa kuphwanya mfundo mu njira ya excretion, kukula kwa hypervitaminosis kumawonedwa. Izi zitha kukhala zachilendo kwa anthu omwe amatha kugwiritsa ntchito mankhwala osokoneza bongo kwa nthawi yayitali okhala ndi mankhwala ambiri a mankhwala a lipoic.
Kuchuluka kwa mavitamini m'thupi kumawonetsedwa ndi mawonekedwe a kutentha kwa mtima, kuchuluka kwa madzi am'mimba, mawonekedwe a zowawa m'dera la epigastric. Hypervitaminosis imatha kudziwonekeranso ngati mawonekedwe amtundu wakhungu pakhungu la thupi.
Kukonzekera ndi zakudya zowonjezera za mankhwala a lipoic acid, zikuwonetsa
Pakadali pano, mankhwala osokoneza bongo komanso zakudya zomwe zili ndi vitaminiyi akupangidwa.
Mankhwala amapangidwa kuti athandizidwe ndi mankhwala osokoneza bongo ngati pakubwera matenda osiyanasiyana ogwirizana ndi kusowa kwa lipoic acid.
Zowonjezera zimalimbikitsidwa kuti zigwiritsidwe ntchito kuti muchepetse kusokonezeka kwa thupi.
Kugwiritsa ntchito mankhwala, kuphatikizapo lipoic acid, kumachitika nthawi zambiri wodwala akazindikira matenda otsatirawa:
- mitundu yosiyanasiyana ya neuropathy;
- zovuta mu chiwindi;
- mavuto mu mtima dongosolo.
Mankhwala amapezeka mu mawonekedwe a mapiritsi a kapisozi ndi yankho la jakisoni.
Zowonjezera zimapezeka pokhapokha ngati makapisozi ndi mapiritsi.
Mankhwala omwe ali ndi lipoic acid ndi awa:
- Mgwirizano. Amapezeka mu mawonekedwe a mapiritsi ndipo yang'anani kwambiri pakukonzekera njira zopangira jakisoni wambiri.
- Lipamide Mankhwala amapezeka monga mapiritsi.
- Lipoic acid. Mankhwala amagulitsidwa mwanjira ya mapiritsi ndi yankho la jekeseni wamitsempha.
- Lipothioxone ndi njira yokonzekera mayankho omwe amapangira jakisoni wambiri.
- Neuroleipone. Mankhwala amapangidwa mwa mawonekedwe a makapisozi ogwiritsira ntchito pakamwa ndikuyang'anitsitsa pokonzekera yankho la jekeseni wamkati.
- Thiogamma - yopangidwa mwanjira ya mapiritsi ndikuzama. Cholinga cha kukonzekera.
- Thioctic acid - mankhwalawa ali ngati mapiritsi.
Monga chigawo chimodzi, lipoic acid imaphatikizidwa pazinthu zotsatirazi zakudya:
- Antioxidant ochokera ku NSP;
- Alpha Lipoic Acid Kuchokera ku DHC;
- Alpha Lipoic Acid kuchokera ku Solgar;
- Alpha D3 - Teva;
- Gastrofilin Plus;
- Nutricoenzyme Q10 wokhala ndi alpha lipoic acid kuchokera ku Solgar.
Lipoic acid ndi gawo limodzi mwa mitundu ingapo ya multivitamin:
- Matenda A Chiwerewere.
- Zotsatira za Alfabeti.
- Zimagwirizana ndi matenda a shuga.
- Zimagwirizana ndi Magetsi.
Lipoic acid umagwiritsidwa ntchito pochita prophylactic kapena ngati gawo limodzi popangika matenda osiyanasiyana. Monga njira yodzitetezera, tikulimbikitsidwa kugwiritsa ntchito zowonjezera zowonjezera pakudya ndi ma poltivitamini. Zakudya za tsiku ndi tsiku za lipoic acid mukamagwiritsa ntchito zakudya zowonjezera ziyenera kukhala 25-50 mg. Popanga zovuta kuthandizira matenda, mlingo wa lipoic acid wotengedwa umatha kukhala 600 mg tsiku lililonse.
Ubwino wa lipoic acid kwa munthu wodwala matenda ashuga adzaphatikizidwa mu kanema munkhaniyi.
