Cholinga chake chachikulu, chomwe mankhwalawa Galvus ali nacho, ndikutsitsa kapamba.
Zotsatira zake, thupi la wodwalayo limayamba kugwira ntchito pogwiritsa ntchito mphamvu zake, motero mkhalidwe wake umakhala bwino.
Ndizofunikira kudziwa kuti ndemanga za Galvus ndi zabwino kwambiri, zomwe zimatsimikizira kuyenera kwake mu ulesi wa matenda ashuga, ngakhale mu mawonekedwe owopsa komanso osakhazikika.
Kufotokozera kwathunthu, cholinga
Galvus ali ndi mawonekedwe ake monga vidagliptin.
Vidagliptin imatha kukhala ndi mphamvu yolimbikitsira kapamba wa wodwalayo, mwachitsanzo pazogwiritsira ntchito zake. Zotsatira zake, kuphatikiza kwa ma peptides osiyanasiyana opangidwa ndi gland awa.
Tiyenera kudziwa kuti nthawi yomweyo kapangidwe ka Galvus si mankhwala osokoneza bongo amodzi, popeza kuwonjezera pa chinthu chomwe chimagwira ntchito chimaphatikizanso zinthu zina zamankhwala othandizira zomwe zimathandizira kuyamwa kwa thupi la munthu.
Mankhwala a Galvus amagwiritsidwa ntchito pochiza matenda a shuga 2
- Amamuwona ngati mankhwala okhawo omwe amagwiritsidwa ntchito ngati njira yayikulu yothandizira pogwiritsa ntchito zakudya komanso masewera olimbitsa thupi. Kuphatikiza apo, ziwerengero zamankhwala zikuwonetsa kuti kugwiritsidwa ntchito kwake ndi kwapamwamba kwambiri, ndipo chithandizo chamankhwala ndikulimbikira komanso chokhalitsa.
- Amaloledwa kuti agwiritse ntchito ngati gawo la zovuta kuchizira koyambirira kwa chithandizo cha matenda a shuga 2 ngati wodwalayo alibe phindu lalikulu pazochita zolimbitsa thupi ndi zakudya.
- Pali mitundu yosiyanasiyana ya mankhwala omwe afotokozedwa otchedwa Galvus Met. Amasiyana ndi mankhwala omwe amapezeka ndiwofatsa thupi la wodwalayo.
- Pomwe mankhwalawa samapereka, amaloledwa kuti azigwiritsa ntchito limodzi ndi mankhwala osiyanasiyana omwe ali ndi insulin komanso zinthu zina zomwe zimapangitsa kapamba.
Endocrinologist ayenera kudziwa njira yamankhwala ndi kapangidwe kake kwa wodwala matenda a shuga. Monga tawonetsa kale, mankhwalawa amtunduwu amatha kugwiritsidwa ntchito ngati mankhwala a mtundu wa mono kapena gawo limodzi lokhala ndi mitundu iwiri kapena itatu. Pankhaniyi, zakudya zovomerezeka ziyenera kutsatiridwa, ndipo wodwalayo ayenera kuchita masewera olimbitsa thupi kuyambira tsiku lililonse.
Kuphatikiza pazotsatira zabwino zomwe munagwiritsa ntchito mankhwalawo, pali ngozi yowonekera komanso zotsatira zoyipa. Zotsatira zoyipazi zingathe kukhala ndi izi:
- kupezeka kwa mutu wakuthwa komanso chizungulire chosafupika.
- mawonekedwe a kunjenjemera.
- kupezeka kwa kumverera kozizira.
- kupezeka kwa ululu wam'mimba, komanso kupweteka m'malo ena a thupi.
- kupezeka kwa ziwengo.
- kuphwanya kwam'mimba thirakiti.
- Kuchepetsa chitetezo cha mthupi.
- kutayika kwa magwiridwe, kutopa kwambiri.
- zotupa zosiyanasiyana pakhungu.
Kuphatikiza apo, pamakhala kuchuluka kwina kwa matenda osachiritsika, makamaka chiwindi ndi kapamba.
Malangizo ogwiritsira ntchito mankhwalawa
Ngati wodwala yemwe ali ndi matenda a shuga adayikidwa Galvus, malangizo ogwiritsira ntchito ayenera kuphunziridwa ndi iye choyamba. Chowonadi ndi chakuti chida ichi chimasankhidwa mosamalitsa payekhapayekha, kutengera kuzika kwamphamvu komwe kumakhazikitsidwa wodwalayo, komanso kuganizira momwe tsankho limaperekera. Milandu iyi, nthawi zambiri malinga ndi mankhwala a endocrinologist, mankhwalawo amatengedwa pakamwa, ngakhale wodwala atha kudya chiyani.
M'malo omwe Galvus, ndipo ili ndi dzina lake la Chilatini, amasankhidwa ndi endocrinologist ngati gawo la zovuta ndi Metformin, thiazolidinedione kapena insulin, komanso monotherapy. Wodwala nthawi zambiri amapatsidwa kumwa Mlingo wa mankhwalawa 50 mpaka 100 mg patsiku. Mofananamo, wodwala akakhala kuti ali ndi vuto lalikulu, kugwiritsa ntchito mankhwalawa kuti akhazikitse mkhalidwe wake, chizolowezi cha tsiku ndi tsiku chimawonjezeka mpaka mamiligalamu 100. Kuphatikiza apo, mlingo womwewo umatha kuwonetsedwa kwa wodwala ngakhale mankhwala atamupangira ngati gawo la zovuta mankhwala.
Mlanduwo ukalandira mlingo wocheperako, umamwa kamodzi, m'mawa usanadye kapena ukadya. Ngati mwayikiridwa mlingo waukulu, ndiye kuti phwando limagawidwa pawiri, pamene gawo loyamba limatengedwa ndi kuchuluka kwa 50 mg m'mawa, ndipo lachiwiri madzulo. Ngati wodwala, pazifukwa zoposa zomwe sangathe, atasowa muyeso umodzi wa mankhwalawa, ndikofunikira panthawi yoyamba kubwereza kuperewera kotereku, osapitirira muyeso womwe wafotokozedwa ndi adokotala.
Mulimonsemo, mlingo woyenera wa tsiku lililonse wa mankhwalawa sayenera kupitirira 100 mg. Mukachulukitsa, mutha kuyambitsa chiwindi ndi impso za wodwalayo. Mwakutero, ku Russia kuti agule mankhwala osokoneza bongo a mtundu uwu ndizotheka pokhapokha akaperekedwe mankhwala. Za mtengo, ndiye 28 tabu. mankhwala Galvus 50mg. mtengo pafupifupi ruble 1300. M'mafakitare opezeka pa intaneti, mtengo wa mankhwalawa ukhoza kukhala wotsika mtengo kwambiri.
Ponena za fanizo ndi mitundu ya mankhwala omwe afotokozedwawo, motsutsana ndi endocrinologist mu milandu yayikulu, komanso pomwe wodwala ali ndi zaka 60 kapena wosalolera mbali zina za mankhwalawa, ayenera kumwa mankhwala monga Galvus Met. Imakhala ndi mphamvu yofanana ndi Galvus 50 mg, koma ilibe mphamvu pach chiwindi ndi impso za wodwalayo.
Ponena za fanizo mwachindunji, ndiye kuti Galvus mu mtundu wawo ali ndi mankhwala monga Onglisa ndi Januvius. Mtengo wawo umakhala wocheperako poyerekeza ndi woyambayo, koma panthawi imodzimodzi pakugwiritsa ntchito kwawo komanso kugwiritsa ntchito bwino amatha kusintha magome a Galvus.
Mulimonsemo, kuikidwa kwa analogi ya mankhwalawa kuyenera kuyanjanitsidwa ndi endocrinologist.
Kuphwanya kwakukulu kukugwiritsa ntchito Galvus
Monga mankhwala aliwonse, Galvus ili ndi contraindication ake.
Malangizo ogwiritsira ntchito mankhwalawa akuwonetsa kukhalapo kwa zovuta zonse zotsutsana ndi mankhwala.
Kutsatira ndi contraindication kosonyezedwa malangizo kumakhala kofunikira mukamagwiritsa ntchito mankhwalawa.
Mfundo zazikuluzikulu ndi izi:
- Kupezeka kwa tsankho kapena vuto lililonse ndi mankhwala omwe amapezeka mu mankhwala.
- Kukhalapo kwa kulephera kwa impso, matenda a impso kapena kusokonekera ntchito.
- Kukhalapo kwa kutentha kwambiri, kutsekula m'mimba, komanso kusanza, komwe kumatha kukhala chizindikiro chowonjezera cha matenda a impso komanso kuwonekera kwa matenda opatsirana mwa wodwala.
- Ziwengo
- Kulephera kwa impso, komanso matenda ena okhudzana ndi omwe atha kukhala kuphwanya ntchito zawo.
- Myocardial infarction, mtima kusakwanira ndi matenda ena a mtima dongosolo.
- Matenda opatsirana.
Kuphatikiza apo, chosemphana ndi momwe ntchito ikugwiritsidwira ntchito ndi kukhalapo kwa matenda ashuga a ketoacidosis ndi lactic acidosis, motsutsana ndi maziko a chikomokere kapena boma.
Kuphatikiza apo, Glavus salimbikitsidwa kuti muzigwiritsidwa ntchito pakakhala pakati, komanso nthawi yonse yodyetsa mwana. Kwa anthu omwe amamwa mowa mopitirira muyeso, mankhwalawa amaletsedwanso. Odwala a zaka zopitilira 60 omwe akuwonetsedwa kuti amamwa mankhwalawa moyang'aniridwa ndi dokotala amayeneranso kukhala m'gulu la odwala. Kuphatikiza apo, kuvomereza kwake nkoletsedwa kwa anthu ochepera zaka 18, izi ndichifukwa choti odwala omwe ali m'mazaka awa amakhala omvera kwambiri pazinthu izi za mankhwalawa monga metformin.
Komanso, odwala onse omwe ali ndi matenda a shuga a mtundu wachiwiri, limodzi ndi kumwa mankhwalawa, amalimbikitsidwa kuti azitsatira zakudya zochepa, momwe kudya calorie sikudzaposa 1000 patsiku. Ndizofunikanso kudziwa kuti kukonzekera kwa Galvus kapena Galvus Meta kumakhala ndi zotsutsana monga kukhalapo kwa lactic acidosis. Vutoli limadziwika ndi mtundu wa 1 shuga mellitus, chifukwa chake saloledwa kugwiritsa ntchito mankhwalawo.
M'pofunika kudziwa padera kuti monga cholowa m'malo mwa mankhwala omwe alipo pamaso pa omwe akufotokozedwa, ma endocrinologists nthawi zambiri amapereka mankhwala - mankhwala a Galvus Met. Zimakhala zofewa ndipo zimakhudza impso ndi chiwindi monga momwe Galvus mwiniwakeyo.
M'malo mwake amatengedwa pakamwa, kutsukidwa ndi madzi ambiri, pomwe mlingo wa mankhwala wotere suyenera kupitilira 100 mg.
Zokhudza chithandizo cha amayi apakati
Ngakhale kuti mankhwalawo amafotokozedwa kalekale ngati munagwiritsidwa ntchito ngati mankhwala, zotsatira zake pa thupi la amayi apakati komanso oyamwitsa sizinaphunzire. Pokhudzana ndi izi, kumwa mankhwalawa osavomerezeka mpaka kutenga pakati. Momwemonso, chithandizo ndi Metformin chikufunika, endocrinologist amatha kusankha mankhwala ena omwe zotsatira za thupi la amayi apakati zidaphunziridwa kale.
Potere, amayi apakati amafunika kuyeza glucose wamagazi ndi glucometer nthawi yonse ya chithandizo. Ngati izi sizichitika, pamakhala chiwopsezo cha kubadwa kwatsopano mwa mwana wosabadwa. Choyipa chachikulu kwambiri, kufa kwa fetal kumachitika. Chilichonse chomwe chingachitike, odwala akulangizidwa kuti agwiritse ntchito jakisoni wa insulin kuti achulukitse chizindikiro ichi.
Kafukufuku wachitika mpaka pano akuwonetsa kuti mayi wapakati akhoza, popanda kuvulaza thanzi lake, kumwa mlingo wa Galvus womwe umaposa mlingo wambiri pafupifupi nthawi mazana awiri. Anomalies mukukula kwa mwana wosabadwayo kapena kuphwanya kwake sikulembedwanso. Tsoka ilo, zowerengera izi ndizokhazikika, komanso deta pazotsatira za mankhwalawa pakupanga mkaka wa m'mawere pakudya.
Izi zimatithandizanso kudziwa kuti dotolo samalangizidwa kuti atengere amayi oyamwitsa.
Zofananira zambiri
Kuphatikiza pa Galvus, mankhwala ena omwe angaganiziridwe monga ena amafanananso ndi zotsatira zake.
Mankhwala monga Baeta, Januvia, Onglisa amatengedwa ngati mankhwala a analogue.
Onsewa amakhala ndi mphamvu yolimbitsa thupi la wodwalayo, bola atengedwa chakudya.
Zotsatira zotsatila zama mankhwalawa zidalembedwa ndi zotsatirazi zomwe zimapangitsa thupi la wodwala yemwe ali ndi mtundu wa matenda a shuga 2:
- Kuchulukitsa kwa insulin. Izi zimachitika pakudya, komanso ngati magazi a shuga apitilira 5-5,5 mmol / L. Zotsatira zake, kuchepa kwakukulu kwamagazi a shuga m'magazi ndikupanga zizindikiro za hypoglycemia sikuchitika.
- Kuchepetsa kaphatikizidwe kamatenda a glucogon m'magazi. Chifukwa chake, njira yolepheretsa kutulutsidwa kwa glucose m'chiwindi chachikulu imatheka.
- Kuchepetsa chilala chifukwa chapanikizidwe m'malo opangira ubongo.
- Kuwonjezeka kwa kutalika kwa chakudya kumakhala m'mimba mwa wodwala. Zotsatira zake, kugaya chakudya m'matumbo ang'onoang'ono kumachitika m'magawo ang'onoang'ono. Chifukwa chake, glucose amalowetsedwa pang'onopang'ono ndipo ndizotheka kupewa kukula kwa chikhalidwe monga hyperglycemia mutatha kudya.
- Kuchulukitsa kwa kuchuluka kwa ma islet cell mu kapamba, omwe amawateteza kuti asafooke.
- Kukonzanso kwa mtima ndi mantha dongosolo. Nthawi yomweyo, kafukufuku wazokhudza izi sanachitikebe mwadongosolo ndipo pali deta yokhayo yokhudza momwe mankhwalawa angatithandizire.
Ngakhale zotsatira zofanana, onse omwe adanenedwa ali ndi makina awo ochitira, mwachitsanzo, Baeta ndi Viktoza amatsata zotsatira za insulin. Ponena za Januvius, Galvus, ndi Onglise, amachita zinthu ngati glucagon-peptides. Pokhudzana ndi izi, ndi akatswiri a endocrinologist okhawo omwe amatha kusankha mtundu wa mankhwala kapena mankhwala.
Chifukwa chake, simuyenera kugula mankhwalawa omwe ali ofanana ndi Galvus popanga osakambirana ndi iye, mwinanso m'malo momupeza njira yothandizira, vuto la wodwalayo lingakulire. Pa mankhwala othandizira, muyenera kutsatira zakudya zamafuta ochepa komanso kuchita masewera olimbitsa thupi a matenda amtundu uliwonse.
Kanemayo munkhaniyi amakamba za matenda ashuga komanso zomwe zimayambitsa.
