GLYFORMIN WA MATENDA ASHUGA

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Gliformin: ndi liti ndipo ndi liti zomwe zimayikidwa

Matenda a shuga amtundu wachiwiri amadziwika, mosiyana ndi oyambayo, osati kuchepa kwa kupangika kwa insulin ndi kapamba, koma kuchepa kwenikweni mu chidwi cha minofu yake. Zotsatira zake, ma hormoni ochulukirapo amaphatikizidwa m'thupi la anthu odwala matenda ashuga kuposa momwe amafunikira, izi zimapangitsa kuti poizoni muwonongeke.

Chifukwa chake, pochizira matendawa, mankhwalawa amagwiritsidwa ntchito omwe amatha kuchepetsa kuyamwa kwa glucose kuchokera m'matumbo, kukulitsa chidwi cha minofu kupita ku insulin ya mahomoni, komanso kuwonjezera kuchuluka kwa shuga.

Gliformin ili ndi zinthu zonsezi, ndipo kuphatikiza apo kumakhala kukhazikika (ngati kuli kwabwinobwino) ndikuchepetsa thupi, zomwe nthawi zambiri zimakhudza odwala omwe ali ndi matenda amtundu II. Ndi matenda osiyanasiyana omwe amatsimikiziridwa, endocrinologist amaika kwa wodwala mu mlingo womwe umasankhidwa payekha, kutengera zonse.

Kapangidwe ka mankhwala ndi mtengo wake

Mankhwala ochizira matenda a shuga Glyformin amapezeka mu mitundu itatu: 250 mg, 500 mg, 850 mg, 1 g.

Chofunikira chachikulu ndicho metformin, ndende yomwe imasankha kuchuluka kwa piritsi limodzi. Kugwiritsa ntchito bwino kwake kumatha kuchitika pokhapokha thupi likapitiliza kupanga insulini kapena ngati adabayidwa. Palibe mahomoni, chithandizo cha metformin sichothandiza kwenikweni.

Tiyeni tiwone mwatsatanetsatane:

Metformin imakulitsa kapena kubwezeretsa (pakakhala kuti palibe kwathunthu) chidwi cha maselo a thupi kupita ku insulini, makamaka zotumphukira. Palinso kuwonjezeka kwa kulumikizana kwa mahomoni ndi ma receptors, pomwe kuchulukitsa kwa glucose kumakulanso ndi maselo ndi ubongo, matumbo, khungu, chiwindi.
Metformin imachepetsa kwambiri kupanga shuga ndi chiwindi, zomwe, mwachidziwikire, zimawonekera mu mulingo wake m'magazi. Ndipo mwa odwala omwe ali ndi thupi lochulukirapo, kuchepa kwake kosalala kumachitika, izi zimathandiza kukhala ndi thanzi labwino.
Chuma china chabwino cha metformin ndi mphamvu ya anorexigenic, kapena, mwachidule, kuchepa kwa chilimbikitso. Imadziwonetsera yolumikizana mwachindunji ndi chigawo cham'mimba ndi chapamimba, osatengera momwe magawo a ubongo amathandizira. Kutsika kwakudya mwachilengedwe kumayambitsa kuchepa kwa chakudya, zomwe zikutanthauza kuti kuchuluka kwa glucose kumacheperanso.
Metformin imathandizanso kuti mawonekedwe osokoneza bongo azidumphira glycemia atatha kudya pang'onopang'ono kuyamwa kwa chakudya cham'mimba.
Mankhwala amathandizira kugwiritsidwa ntchito kwa shuga m'thupi ndi maselo a m'mimba.

Chifukwa chake, chosakaniza chachikulu cha Glformin chitha kufotokozedwa kuti ndi cha antihyperglycemic, i.e. osalola kuchuluka kwa glucose, m'malo monga hypoglycemic.

Zowonjezera zina mu Glformin, kutengera mlingo, zitha kukhala:

Calcium calcium phosphate dihydrate;
Kashiamu yovunda;
Sorbitol;

Povidone;
Wowuma mbatata;
Stearic acid.

Chigoba cha mankhwalawa chimakhala ndi:

Hypromellose;
Talcum ufa;
Macrogol.

Mtengo wa mankhwalawa umatha kusiyanasiyana malinga ndi Mlingo, wopanga, gawo logulitsidwa, kuchuluka kwa mapiritsi omwe ali phukusi. Pafupifupi, maphunziro mwezi uliwonse azitha kugula ma ruble 200-300.

Masiku ano, mankhwalawa amapangidwa ndi makampani angapo. Mwa izi, zofala kwambiri ku Russia:

Nycomed (Switzerland);
Akrikhin (Russia);
GNIISKLS (Russia).

Njira ya pharmacological ndi njira yogwiritsira ntchito

Kuchita kwa mankhwala a Gliformin kumachitika chifukwa cha mankhwala ake othandizira.

Cholinga chake ndi:

Kuponderezedwa kwa dongosolo la kupangika kwa shuga mu chiwindi;
Kulimbikitsa njira yogawa chakudya, makamaka shuga;
Kuchuluka kwa shuga komwe kumachokera m'matumbo;
Kulimbitsa zomangira za insulin ndi ma receptors ndi minofu;
Kuchepetsa thupi, kuchepa kwamtima.

Mlingo wothandizidwa ndi endocrinologist, kutengera zosowa za thupi. Itha kukhala: 250 mg., 500 mg., 850 mg., 1g.

Kumayambiriro koyambirira m'masiku atatu oyamba, odwala omwe ali ndi insulin amalembedwa kawiri mlingo wa 1 kapena katatu mlingo wa 500 mg, pamasiku otsatirawa mpaka kumapeto kwa sabata lachiwiri la chithandizo - katatu patsiku 1 g.
Kenako njira yamankhwala imasinthidwa malinga ndi mphamvu ya shuga ndi mphamvu ya mankhwalawo pagulu la wodwala linalake.
Nthawi zambiri, mankhwala owonjezera samapitirira kawiri pa 1 ga pa nthawi.

Zotsatira zoyipa ndi contraindication

Mankhwalawa ali ndi zotsutsana zotsatirazi:

Ketoacidosis ndi vuto lowopsa lomwe limayamba chifukwa cha insulin yonse kapena kusapezeka;
Matenda a shuga - kulephera kuzindikira komanso kusowa poyambira;
Lactic acidosis - kuchuluka kwambiri kwa lactic acid;
Matenda ndi matenda a impso, chiwindi;
Mtima, kulephera m'mapapo;
Myocardial minofu infarction;
Kuchepetsa mkaka ndi pakati;
Matenda opatsirana, kuvulala kwambiri;
Ntchito zazikulu zomwe zakonzedwa posachedwa.

Mankhwalawa ali ndi zovuta zochepa, koma mwa iwo:

Khungu limakhudza khungu;
Kuphwanya chopondapo (kutsegula m'mimba), komanso kusanza;
Kulawa kwachitsulo mkamwa;
Pogwiritsa ntchito nthawi yayitali, mavitamini B amachepetsa;
Choyipa chowopsa kwambiri ndi lacticiadosis, mawonekedwe ake amafunikira kukana Glyformin mwachangu.

Zofananira za Gliformin ndi kusiyana kwawo

Mankhwala Glformin ali ndi mitundu ingapo. Zina mwa izo ndi:

Glucophage;
Siofor;
Metfogram.

Onsewa ali ndi mankhwala ofanana ndipo amafunidwanso m'njira zofananira ndi Gliformin. Izi ndichifukwa choti zomwe zimagwiritsidwa ntchito ndi mankhwalawa ndizofanana. Kusiyana komwe kulipo pakati pawo ndikungotengera mtengo ndi mlingo womwe wapatsidwa

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