Desmopressin ndi analogue yopanga ya vasopressin. Mankhwala alibe wamphamvu poizoni thupi, si mutagen. Lemberani mukakambirana ndi dokotala; kudzipereka kungathe kuvulaza thanzi komanso moyo wa wodwala.
Dzinalo Losayenerana
Dzinalo dzina lake ndi Desmopressin. Mu Chilatini - Desmopressin.
Desmopressin ndi analogue yopanga ya vasopressin.
Ath
Khodi yamankhwala ndi H01BA02.
Kutulutsa Fomu
Mankhwalawa amapangidwa m'mitundu ingapo. Musanasankhe mawonekedwe, muyenera kufunsa dokotala kuti mupeze yoyenera yothandizira matenda.
Njira yothetsera jakisoni imayendetsedwa kudzera mu mnofu, kudzera m'mitsempha, mozungulira.
Mapiritsi
Mankhwala amapezeka mu mawonekedwe a mapiritsi oyera, ozungulira. Kumbali imodzi kuli mawu olembedwa "D1" kapena "D2". Pa mzere wachiwiri wogawa. Kuphatikiza pazogwira, desmopressin, kaphatikizidwe kamaphatikizidwe ndi magnesium stearate, wowuma wa mbatata, povidone-K30, lactose monohydrate.
Mankhwala amapezeka mu mawonekedwe a mapiritsi oyera, ozungulira.
Madontho
Madontho a Nasal ndi madzi opanda khungu. Omwe amathandizira ndi chlorobutanol, sodium chloride, madzi, hydrochloric acid. Mlingo wa 0.1 mg pa 1 ml.
Utsi
Ndiwisi yabwino. Yokhala ndi botolo lapadera ndi dispenser. Omwe amathandizira ndi potaziyamu sorbate, madzi, hydrochloric acid, sodium chloride.
Njira yamachitidwe
Mankhwala ali ndi antiidiuretic thupi la munthu.
Zomwe zimagwiritsidwa ntchito ndi molekyulu yosinthika ya vasopressin ya mahomoni. Mankhwala akalowa m'thupi, ma receptor apadera amayamba, chifukwa chomwe njira yobwezeretsedwera madzi imatheka. Kuphatikizika kwa magazi kumakhala bwino.
Odwala omwe ali ndi hemophilia, mankhwalawa amonjezera kuwonjezeka kwa 8 katatu. Kuwonjezeka kwa kuchuluka kwa plasminogen m'madzi am'madzi amadziwika.
Kutsata kwamkati kumakulolani kuti mukwaniritse zotsatira zake.
Mankhwala amasintha magazi.
Pharmacokinetics
Mankhwala zimapukusidwa mu chiwindi. Amachotsedwa ndi mkodzo.
Kutha kwa theka-moyo kumapangitsa mphindi 75. Pankhaniyi, patatha maola ochepa, kuchuluka kwakukulu kwa mankhwalawo m'magazi a wodwalayo kumadziwika. Kutheka kwakukulu kumawonedwa maola 1.5-2 pambuyo pa kukhazikitsa.
Zizindikiro zogwiritsidwa ntchito
Mankhwalawa amalembera polyuria, zochizira matenda a shuga, chifukwa cha nocturia, hemophilia, matenda a Willebrand. Spray ndi madontho amagwiritsidwa ntchito ngati gawo la zovuta kuchiza kwa nocturnal enuresis, kwamikodzo incontinence. Kuphatikiza apo, madontho amagwiritsidwa ntchito atagwira ntchito pa pituitary gland.
Contraindication
Amaletsedwa kuchiza ndi desmopressin chifukwa cha anuria, kupezeka kwa sayanjana, munthu wosalolera pazigawo za mankhwala, komanso chifukwa cha plasma hypoosmolality. Mankhwalawa sagwiritsidwa ntchito polydipsia, kusunga kwamadzi, mtima. Mankhwalawa sagwiritsidwa ntchito mothandizidwa ndi matenda osakhazikika a angina ndi matenda a 2 von Willebrand.
Mankhwalawa satumikiridwa kudzera m'mitsempha ndi osakhazikika a angina.
Ndi chisamaliro
Ngati kuphwanya kwa madzi-electrolyte bwino, chikhodzodzo, matenda a mtima kapena impso, chiopsezo cha kuchuluka kwazovuta zam'mimba, kusamala kuyenera kuchitika pakumwa. Chitsulo chobera chimawonedwa ngati choposa zaka 65.
Momwe mungatengere Desmopressin
Mlingo ndi dongosolo regimen zimadalira matenda, mikhalidwe ya wodwala. Ayenera kusankhidwa limodzi ndi adotolo. Muyenera kudziwa bwino malangizo ogwiritsa ntchito.
Mlingo woyambirira wa madontho amphuno, kutsitsi kumasiyana 10 mpaka 40 mcg patsiku. Iyenera kutengedwa kangapo. Ana osakwana zaka 12 adzafunika kusintha. Kwa iwo, mlingo wa ma 5 mpaka 30 makilogalamu amasankhidwa masana.
Pogwiritsa ntchito jakisoni wa akulu, mulingo wambiri umachokera ku 1 mpaka 4 μg pa kilogalamu imodzi ya thupi. Muubwana, ma microgram a 0,4-2 akuyenera kuperekedwa.
Ngati chithandizo sichibweretsa zomwe zikuyembekezeka mkati mwa sabata, mlingo wake uyenera kusintha.
Ngati chithandizo sichibweretsa zomwe zikuyembekezeka mkati mwa sabata, mlingo wake uyenera kusintha.
Ndi matenda ashuga
Mankhwalawa ayenera kugwiritsidwa ntchito mosamala komanso pokhapokha ngati wodwala akuwatsogolera.
Zotsatira zoyipa
Chizungulire, kupweteka mutu, kusokonezeka ndizotheka. Nthawi zambiri, odwala amadwala. Kulemera kwa thupi kumatha kuchuluka, rhinitis ikhoza kuchitika. Odwala ena, nembanemba ya mphuno imatupa. Kusoka, mseru, komanso kupweteka m'mimba ndikotheka. Kuthamanga kwa magazi kumatha kuchuluka kapena kuchepa. Nthawi zina oliguria, kutentha kwa moto, thupi limagwidwa. Hyponatremia ikhoza kuchitika. Mukamagwiritsa ntchito jakisoni, ululu utha kuzindikirika pamalo opangira jakisoni. Ngati mankhwalawa amagwiritsidwa ntchito pochiza ana osakwana miyezi 12, khunyu ndikotheka.
Zokhudza mphamvu pakuwongolera njira
Kugwiritsa ntchito mankhwalawa sikukhudza kuyendetsa galimoto.
Malangizo apadera
Anthu ena ayenera kutsatira malangizo ena.
Gwiritsani ntchito mu ukalamba
Pambuyo pa zaka 65, kusamala kuyenera kugwiritsidwa ntchito mukamagwiritsa ntchito mankhwalawa.
Kupangira Desmopressin kwa Ana
Itha kugwiritsidwa ntchito pochiza ana kuyambira miyezi itatu. Kusintha kwa magazi kuyenera.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Amagwiritsidwa ntchito mosamala. Mankhwalawa amachitika moyang'aniridwa ndi dokotala.
Pa nthawi yoyembekezera, mankhwalawa amagwiritsidwa ntchito mosamala.
Bongo
Zizindikiro zake ndi hyponatremia, kusungira kwamadzi. Kuti athetse vutoli, ma diuretics amagwiritsidwa ntchito, yankho lapadera limaperekedwa.
Kuchita ndi mankhwala ena
Pogwiritsa ntchito munthawi yomweyo ndi maopodi okhala ndi dopamine, mphamvu ya Pressor imatheka. Lithium carbonate imafooketsa mphamvu ya mankhwalawa. Chenjezo liyenera kumwedwa pophatikiza mankhwalawa ndi mankhwala omwe amachititsa kuti mahomoni a antidiuretic atulutsidwe.
Kuyenderana ndi mowa
Kumwa mowa panthawi yamankhwala sikulimbikitsidwa, chifukwa kumapangitsa kuti mankhwalawa akhale othandiza.
Analogi
Mankhwalawa ali ndi mitundu yofananira. Analogs ndi mapiritsi Minirin, Nativa, Adiuretin, Spayneks zikumapeto, Vasomirin. Desmopressin Acetate imagwiritsidwanso ntchito. Palinso ma kapisozi ena, mapiritsi ndi mayankho omwe ali ndi katundu wa antidiuretic. Mwina ntchito mankhwala wowerengeka.
Minirin ndi analogue ya Desmopressin.
Zotsatira za Holiday Desmopressin Holiday
Mutha kugula mankhwala ku pharmacy iliyonse.
Kodi ndingagule popanda kulandira mankhwala?
Ndizosatheka kugula mankhwala popanda mankhwala.
Mtengo wa Desmopressin
Mtengo ndiwosiyanasiyana m'magawo osiyanasiyana, ma pharmacies. Choyimira chimadaliranso mtundu wa mankhwalawa omwe munthu amamwa. Mutha kugula madontho pafupifupi rubles 2,400, mudzalipira zambiri jakisoni.
Zosungidwa zamankhwala
Sungani mankhwalawo pamalo osavomerezeka ndi ana, kutentha komwe sikupitirira 30 digiri.
Sungani mankhwalawo kuti ana sangathe.
Tsiku lotha ntchito
Mankhwalawa amatha kugwiritsidwa ntchito zaka 2.5. Nthawi imeneyi ikatha, malonda amayenera kutayidwa. Kugwiritsa ntchito mankhwala omwe adatha sikuletsedwa.
Wopanga wa Desmopressin
Mankhwalawa amapangidwa ku Iceland.
Ndemanga za Desmopressin
Mankhwalawa adalandira ndemanga zambiri zabwino.
Madokotala
Anatoly, wazaka 38, Pskov: "Nthawi zambiri ndimapereka mankhwala kwa odwala, chifukwa zovuta sizipezeka, mankhwalawa alibe mankhwala oopsa, amatha kuthana ndi matenda. Nthawi zina zimatenga milungu yambiri kuyesa osiyanasiyana mpaka mutapeza wodwala woyenera, koma pambuyo pake ndi 2-3 tsiku, zotsatira zake zikuwoneka. "
Mankhwalawa amagwiritsidwa ntchito popanga usiku.
Odwala
Denis, wazaka 36, Khabarovsk: "Mwana wanga wamwamuna ali ndi zaka 5, panali zodwala. Adayesa mankhwala osiyanasiyana, koma osagwiritsa ntchito. Dokotala adamuwuza chithandizo cha Desmopressin. Zotsatira sizinawonekere sabata yoyamba, koma njira yothandizirayi idapezekanso. wauka. "
Anna, wazaka 28, Vologda: "Pakupitilizidwa, kuchipatala adapezeka kuti ali ndi matenda a shuga. Ndidapita kwa dokotala wina, ndikhulupirira kuti kulakwitsa. Dotolo adatsimikiza kuti adamupeza ndipo adamuwuza Desmopressin. Adayamba kumva bwino, ludzu lake lidatha usiku. okwera mtengo, koma tsopano muyenera kumamwa nthawi zonse. "