Diroton ndi mankhwala odziwika bwino pothandizira matenda a mtima, kuphatikizapo ochepa matenda oopsa komanso kusakwanira kwa minofu yamtima. Nthawi zambiri amagwiritsidwa ntchito kuphwanya magazi m'matumbo.
ATX
C09AA03
Diroton ndi mankhwala odziwika bwino pothandizira matenda a mtima, kuphatikizapo ochepa matenda oopsa komanso kusakwanira kwa minofu yamtima.
Kutulutsa mafomu ndi kapangidwe kake
Amapezeka m'mapiritsi okha. Pogula, muyenera kulabadira mlingo, kutengera momwe mawonekedwe a mapiritsiwo angakhalire osiyana, ngakhale onse ndi oyera. Chozunguliridwa - 2.5 mg iliyonse, yosalala (mwa mawonekedwe a disk) - 5 mg iliyonse, mawonekedwe osakanikirana - 10 mg ndi 20 mg aliyense.
Maziko a mankhwalawa amasinopril amathandizira ndi magnesium stearate, wowuma, talc ndi calcium hydrogen phosphate.
Kugulitsa ma CD - matuza apadera 14, oikidwa m'makatoni olemba ma pc a 1-4.
Zotsatira za pharmacological
Mankhwalawa ndi ACE inhibitor (angiotensin otembenuza enzyme). Ikamamwa pakamwa, imalowetsedwa mwachangu ndipo imalowa m'magazi. Imathandizira kuchepa kwa magazi, imachepetsa ziwiya zazikulu, zomwe zimapangitsa kuti magazi azikhala bwino mkati. Kutha kwa mtima wopirira zochitika zolimbitsa thupi kumawonjezeka.
Ngati mumwa mankhwalawa pafupipafupi, zimatha kutha kuchepa kwa njira zama hypertrophic mu myocardium.
Ngati mumwa mankhwalawa pafupipafupi, zimatha kutha kuchepa kwa njira zama hypertrophic mu myocardium. Minofu ya mtima yomwe idakhudzidwa ndi ischemia imapereka magazi abwino.
Mothandizidwa ndi chida ichi, ndizotheka kutalikitsa moyo wa anthu omwe mbiri yawo yasonyeza kulephera kwa mtima. Zochita za mankhwalawa zimayamba pafupifupi pakatha ola limodzi, ndipo zochizira zimatha mpaka tsiku.
Ndikasokonezeka pang'ono pakulandila, matendawa amtha kuyamba, omwe pambuyo pake amabweretsa vuto lalikulu kwambiri.
Pharmacokinetics
Kutulutsidwa m'mimba. Pambuyo pake, lisinopril mwachindunji m'madzi a m'magazi amamangiriza kumapangidwe a mapuloteni. The bioavailability wa mankhwala pafupifupi 30%. Mlingo wotsekemera sasintha mwanjira iliyonse posintha zakudya.
Lisinopril sakhala ndi vuto la metabolism, motero amathandizidwa pambuyo pa maola 12 ndi mkodzo wosasinthika.
Zomwe zimathandiza
Kuphatikiza pakuchepetsa kupsinjika, chinthu chimathandizira kuthana ndi matenda ena:
- Matenda oopsa. Mankhwalawa amalembedwa ngati gawo limodzi la mankhwala osokoneza bongo pamodzi ndi mankhwala ena.
- Kulephera kwamtima kosalekeza. Amagwiritsidwa ntchito limodzi ndi digitis decoctions, maphunziro a okodzetsa.
- Matenda a shuga. Amagwiritsidwa ntchito ngati matenda a shuga akuphatikizidwa ndi ochepa hypotension.
- Myocardial infaration. Amasankhidwa kuti azikhala ndi magazi abwinobwino komanso kuti ateteze kukula kwa mtima kulephera kwamanzere.
Kusankha kwa chithandizo kuyenera kuthandizidwa.
Pa kukakamizidwa komwe kumayikidwa
Munthu aliyense ali ndi zisonyezo zake. Mu malangizo ogwiritsira ntchito, palibe zomwe zikuwonetsa kuti mapiritsi amayenera kuthiridwa kuti azikamwa. Chifukwa chake, kufunika kwa kumwa mankhwalawa, ndi mlingo uyenera kutsimikiziridwa ndi dokotala.
Contraindication
Mankhwalawa amalembedwa pokhapokha atalandira zotsatira zoyesedwa kwathunthu kuchipatala. Musanayambe chithandizo, muyenera kuphunzira malangizo mosamala, chifukwa mankhwalawo ali ndi zotsutsana:
- tsankho pamagawo ena;
- zaka za mwana mpaka zaka 6;
- ziwengo (kuthekera kwa edema ya Quincke sikuchotsedwa);
- nthawi ya bere ndi mkaka oyamwa.
Chenjezo liyenera kuchitidwa pamaso pa zina za matenda ndi ma matenda:
- aimpso kuwonongeka;
- stenosis ya ziwiya zazikulu;
- kusowa kwamadzi kwambiri;
- pambuyo kupatsirana kwa impso;
- matenda aakulu amtima;
- kuchepetsedwa kwambiri kukakamizidwa;
- mtima ischemia;
- matenda a shuga;
- matenda okhudza minyewa yolumikizira;
- kuchuluka kwa potaziyamu ndi sodium m'magazi.
Izi zotsutsana zonse ziyenera kukumbukiridwa musanayambe kutenga.
Mwina kukula kwa zovuta komanso zovuta zosafunikira zomwe zimakhudza magwiridwe antchito komanso ziwonetsero zomwe zimachitika m'thupi la wodwalayo.
Momwe angatenge
Mulingo umodzi wa mankhwala patsiku tikulimbikitsidwa. Kusamba ndi madzi. Kugwiritsa ntchito mankhwalawa sikudalira nthawi ya tsiku kapena zakudya, koma ndi bwino kumamwa m'mawa. Pagulu lirilonse la matenda pamakhala dongosolo la mitundu:
- Ndi ochepa matenda oopsa, 10 mg patsiku ndi mankhwala. Kenako amasinthira ku 20 mg, yomwe imawathandiza. Muzovuta kwambiri, kuwonjezeka kwa 40 mg patsiku ndikotheka. Zotsatira zabwino zogwiritsidwa ntchito kwa nthawi yayitali zimachitika pambuyo pa milungu iwiri yothandizira mosalekeza.
- Ndi kukonzanso kwamitsempha yamagazi, mulingo woyenera wa tsiku lililonse sayenera kupitirira 5 mg. Kenako, mankhwalawa amatengera kuuma kwa Zizindikiro za matenda oopsa.
Ngati mukukhala ndi mlingo wambiri wa mankhwala omwe mulibe zotsatira, ndiye kuti mankhwalawo amaloledwa. Mankhwala onse okodzetsa amachotsedwa.
Ngati zizindikiro za kulephera kwa mtima kwapezekapezeka, ndiye kuti lisinopril iyenera kuphatikizidwa ndi okodzetsa. Koma kuchuluka kwa zotsirizira kumachepetsedwa pang'ono.
Ndi osakwanira aimpso ntchito, mlingo umadalira creatinine chilolezo. Kutsika mtengo wovomerezeka, wotsikirapo ndiye mlingo wa lisinopril. Mlingo wowonjezeranso wokonza umatsimikiziridwa ndi zizindikiro zowunikira.
Kumwa mankhwala a shuga
Amasankhidwa muyezo wogwira ntchito. Munthawi yonse yamankhwala, muyenera kuyang'anira kuchuluka kwa shuga m'magazi.
Zotsatira zoyipa
Mutu ndi chizungulire, kutsekula m'mimba, mseru, kufooka kwambiri, kupweteka pachifuwa, chifuwa chamtundu wa nthawi yayitali, khungu lawo siligwirizana.
Zizindikiro zina zimasiyanitsidwa padera, chifukwa kupezeka kwawo kumachitika chifukwa cha kusokonezeka kwa ziwalo zosiyanasiyana.
Matumbo
Matenda a dongosolo logaya chakudya amawonedwa. Zizindikiro zazikulu ndi kutsekula m'mimba, kusanza, kukamwa kowuma, kupweteka kwambiri pamimba, zizindikiro za chiwindi, jaundice ndi kapamba.
Hematopoietic ziwalo
Ngati mankhwalawa sanatengedwe moyenera, dongosolo lamagazi limathanso kuvutika. Zizindikiro zimayamba: neutro- ndi leukopenia, kuchepa magazi, kuchepa ndende ya hemoglobin m'magazi.
Pakati mantha dongosolo
Kuchokera mu dongosolo lamanjenje mumakhala zododometsa, kusokonezeka kwamphamvu ndikugwirizanitsa kayendedwe, kusinthasintha kwa machitidwe, kugona kugona, ndi kusachita chidwi. Nthawi zina, kugwiritsidwa mwala ndi paresthesias kumachitika.
Mbali yamanjenje, zotsatira zoyipa za mankhwalawo zimawonekera mwa kusokonezeka komanso kusokonezeka kwa ndende.
Kuchokera kwamikodzo
Zomwe zimachitika mu kwamikodzo zimawonetsedwa ndi uremia, oliguria, kulephera kwa impso ndi kuchepa kwapadera kwa amuna.
Kuchokera ku kupuma
Zizindikiro za kupuma kukanika: mawonekedwe a chifuwa chouma komanso kuphipha kwa ziwiya za bronchial. Nthawi zina, dyspnea ndi apnea zimadziwika.
Kuchokera pamtima
Zovuta zamkati pamtima zimawonetsedwa ndi kuchepa kwa kuthamanga kwa magazi ndi kukanikiza kupweteka pachifuwa. Tachycardia kapena, mosiyana, bradycardia nthawi zina imadziwika. Mwina kukula kwa myocardial infarction.
Pa khungu
Pa khungu, thupi lawo siligwirizana. Kuyenda ndi ming'oma ndikotheka.
Pali thukuta kwambiri komanso kuwonda kwambiri kwa tsitsi.
Matupi omaliza
Thupi lawo siligwirizana angathe (mpaka angioedema Quincke edema).
Malangizo apadera
Pali malangizo ena apadera mwa malangizo a mankhwalawa. Ayenera kuphunziridwa mosamala kuti apewe zovuta zosafunikira.
Kuyenderana ndi mowa
Kumwa pamodzi ndi zakumwa zoledzeretsa siziyenera kuloledwa, chifukwa chithandizo chonse cha mankhwalawa chatayika.
Kugwiritsa ntchito mankhwala pamodzi ndi zakumwa zoledzeretsa sikuyenera kuloledwa, chifukwa mankhwalawa amawonongeka.
Zokhudza mphamvu pakuwongolera njira
Mankhwalawa amalepheretsa mphamvu yamanjenje, amachepetsa chidwi ndikuwonjezera kutopa ndi ulesi, motero ndibwino kusiya kuyendetsa.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Osati kuperekedwa kwa azimayi munthawi yobala mwana. Lisinopril amawoloka placenta bwino ndipo nthawi zambiri amayambitsa fetal development pathologies. Kugwiritsa ntchito mankhwalawa pambuyo pake kumatha kupangitsa kuti mwana akhanda asabadwe kapena kuti akule bwino kwa aimpso kwa mwana yemwe wabadwa.
Ngati mankhwalawa adatengedwa asanabadwe, muyenera kudziwitsa dokotala za izi. Amayi oterewa amalembetsa, amayang'aniridwa nthawi zonse asanabadwe.
Sitikulimbikitsidwa kumwa mankhwalawa mukamayamwa, chifukwa palibe chidziwitso chokwanira chokhudzana ngati chinthucho chitha kulowa mkaka wa m'mawere. Ngati pakufunika mankhwala, ndi bwino kusiya kudyetsa.
Kupangira Diroton kwa ana
Zopanda kugwiritsa ntchito ana.
Gwiritsani ntchito mu ukalamba
Ndi kusamala kwambiri.
Bongo
Ngati simutsata mlingo woyenera wa mankhwalawa, makamaka pakakhala nthawi yayitali, pakakhala zovuta zosagwiritsa ntchito mankhwala osokoneza bongo:
- kuchepa kwakukulu kwa kuthamanga, kuthamanga kwa magazi m'matumbo, kugwa;
- tachycardia;
- zododometsa, kuchepa chidwi;
- pakamwa kowuma, limodzi ndi ludzu losalekeza;
- ulesi ndi kuchepa kotheka kwa mawonekedwe a Reflex.
Ngati simutsatira kuchuluka kwa mankhwalawa, makamaka akamamwa nthawi yayitali, pakamwa pouma amatha kuwoneka, limodzi ndi ludzu losalekeza.
Ngati zoterezi zikuchitika, wodwalayo ayenera kupita naye kuchipatala mwachangu. Kutenga mankhwalawo amachotsedwa pomwepo. Mankhwala osokoneza bongo amathandizidwa ndi chapamimba. Kenako wodwalayo amapatsidwa mapiritsi angapo a kaboni yodziyimira ndipo amamuika mankhwala, omwe amakhalapo mpaka zizindikiro za bongo zitatha.
Kuchita ndi mankhwala ena
Mukamagwiritsidwa ntchito ndi potaziyamu wokhala ndi okodzetsa, chiopsezo cha hyperkalemia chimawonjezeka. Ndi infusions zotere, ntchito ya impso ndi mtima akuletsa.
Ngati mugwiritsidwa ntchito ndi alpha-blockers, kukakamiza kumatsika, kotero kulamula mosamalitsa ndikofunikira. Mphamvu ya antihypertensive imawonjezeka ndi kugwiritsidwa ntchito kwake palimodzi ndi antidepressants.
Zowerengeka zowonjezera za lisinopril zimachepetsedwa ndi mankhwala ena odana ndi kutupa. Mafuta a makoma a m'matumbo amalephera chifukwa cha mankhwala a antacid.
Amayi omwe akufuna kudziteteza ku mimba yosafunikira ayenera kudziwa kuti mankhwalawa amachepetsa mphamvu ya njira zakulera zapakati.
Momwe mungasinthire
Pali ma analogi angapo omwe ali ndi zofanana zochizira:
- Co Diroton;
- Vitopril;
- Concor;
- Lysinocore;
- Lozap.
Musanagule zina, muyenera kufunsa dokotala kuti mudziwe zoyenera. Katswiri yekha ndi amene anganene kuti ndi chida chiti chothandiza kugwiritsa ntchito.
Kupita kwina mankhwala
Pokhapokha ngati mwalandira dokotala. Sipezeka mwaulere.
Kodi Diroton amawononga ndalama zingati?
Mtengo m'misika yamankhwala ndi pafupifupi 90 ma ruble.
Diroton yosungirako
Sungani m'malo amdima kutentha kwa firiji.
Tsiku lotha ntchito
Zaka zitatu
Ndemanga za Diroton
Omvera zamtima
Zhikhareva O. A., St. Petersburg: "M'pofunika kupereka mankhwala pafupipafupi pamodzi ndi mankhwala a antihypertensive. Pokhala ndi matenda oopsa oopsa, mankhwalawa amayenera kumwa piritsi limodzi 1. Asanaperekane, ndikofunikira kuwunika momwe impso zilili.”
Zubov V. L., Penza: "Mankhwalawa ndiabwino, samaperekanso zovuta zilizonse. Amagwira ntchito mwachangu, koma sayenera odwala onse. Kwa iwo omwe amakhala ndi vuto logontha kwa magazi, kumwa mapiritsi amodzi sikuthandizira kuchepetsa kuthamanga kwa magazi. "Mitsempha ya varicose."
Odwala
A Alexander, wazaka 43, Saratov: "Mankhwalawa siabwino. Koma panali zinthu zina zomwe sizinayende bwino. Mutu wanga unawawa, kutsokomola kosakhazikika ndi zotupa pakhungu. Zonse zidapita mwachangu nditangomwa kumwa. Ndinafunika kusankha mankhwala ena."
Valentina, wazaka 52, ku Moscow: "Dotolo adalimbikitsanso kumwa m'mawa uliwonse. Ndimachita. Zimakhala bwino ndikulandira mlingo uliwonse. Kupanikizika kunabwereranso, mutuwo unayamba kupwetekedwa pang'ono. Matenda anga onse ayenda bwino kwambiri. Njira yachipatala sinatherebe. pitilizani kuvomereza. "
Irina, wazaka 48, Kursk: "Ndi kugwiritsa ntchito mosalekeza, zotsatira zake zimawonekera. Koma kuchokera ku zomwe ndamva, ndinali wotsimikiza kuti ndikalandira mlingo umodzi wokha kuti muchepetse kupanikizika, mankhwalawa sagwira ntchito. Kupanikizika kunakhalabe kwapamwamba, ngakhale kuchuluka kwa kuchuluka ndi kugwiritsidwa ntchito mobwerezabwereza sizinathandize. Ndinayenera kumwa mankhwala ena. "