CardiASK ndi mankhwala amodzi. Imagwira ntchito zingapo nthawi imodzi: imachepetsa kukula kwa kutupa, imalepheretsa dongosolo la gluing mapulaneti, maselo ofiira a m'magazi. Chifukwa cha izi, sikuti zonse zimangokhala bwino, koma chiopsezo chokhala ndi venous thrombosis chimacheperanso. Mankhwalawa sakonda kupsa mtima pakatikati kamatumbo am'mimba kwambiri kuposa mawonekedwe ambiri a gulu la NSAID. Izi ndichifukwa cha kukhalapo kwa nembanemba wapadera wokutira mapiritsi.
Dzinalo Losayenerana
Acetylsalicylic acid (mu Latin - Acetylsalicylic acid).
CardiASK ndi mankhwala amodzi.
ATX
B01AC06 Acetylsalicylic acid
Kutulutsa mafomu ndi kapangidwe kake
Mankhwalawa akhoza kugulidwa kokha ngati mapiritsi. Phukusili lili ndi ma PC 30 kapena 60. Acetylsalicylic acid umagwiritsidwa ntchito ngati chinthu chogwira ntchito. Kuphatikizika kwake piritsi limodzi ndi 50 mg. Ndizotheka kugula mankhwala ndi Mlingo wa yogwira 100 mg. Mankhwala ndi chinthu chimodzi, mankhwala ena omwe amaphatikizidwa samawonetsa ntchito yotsutsa-kutupa ndi antiplatelet:
- stearic acid;
- wowuma chimanga;
- lactose monohydrate (shuga mkaka);
- hydrogenated castor mafuta;
- povidone;
- polysorbate;
- microcrystalline mapadi.
Mankhwalawa akhoza kugulidwa kokha ngati mapiritsi.
Zotsatira za pharmacological
Mankhwala amadziwika ndi zinthu monga: anti-kutupa, antipyretic, analgesic, antiplatelet. Kutsika kwa kutentha kwa thupi kumachitika chifukwa cha kukhudzidwa kwa malo a hypothalamus. Kukula kwa kupweteka kumachepa chifukwa cha mphamvu ya ma salicylates (omwe amachokera ku ASA) kupereka mphamvu pa ntchito ya aldogenic ya bradykinin. Kuphatikiza apo, mankhwalawa amakhudza malo omwe akumvera ululu.
Mankhwala omwe amafunsidwa amakhudza kupanga kwa ma prostaglandins, amaletsa mapangidwe a adenazine triphosphate. Nthawi yomweyo, kuchepa kwa kuchuluka kwa zochitika za hyaluronidase kumadziwika, kuchuluka kwa capillaries kumachepa. Mfundo zoyenera kuchitira NSAIDs ndi zofanana: njira yosasintha ya zoletsa zochitika za cycloo oxygenase isoenzymes imayamba. Mosiyana ndi ma analogu ena, wothandizirayo malinga ndi ASA amasankha COX-1.
Nthawi yomweyo, kupezeka kwa capillaries kumachepa.
Ma enzymes a cycloo oxygenase-1 amawongolera kupanga kwa ma prostaglandins omwe amachititsa kukhulupirika kwam'mimba mucosa, kusamalira zochitika za m'magazi, komanso kuchepa kwa magazi a impso. Ntchito yayikulu ya CardiASK ndikulepheretsa zochitika za ma enzymes izi, zomwe zimayambitsa zovuta zingapo pakugwira ntchito kwa ziwalo ndi machitidwe, mwachitsanzo, kuchepa kwamphamvu kwa kuphatikizana kwa maselo am'magazi, kuphatikiza apo, kudziphatika kwawo kumakoma amitsempha yamagazi kumachepa, monganso kuthekera komamatirana. Zotsatira zake zimakhala zotsutsana.
Nthawi yomweyo, zovuta pamimba zimadziwika. Kuti muchepetse izi, mapiritsiwo amakhala ndi zokutira enteric, chifukwa chomwe chinthu chogwira ntchito chimamasulidwa pang'onopang'ono, njirayi imayamba kukula m'matumbo. Zotsatira zake, mucous membrane wa gastric samawululidwa chifukwa cha zotsatira zoyipa za acetylsalicylic acid, kuchuluka kwa zotsatira zoyipa kumachepa.
Pharmacokinetics
Kutulutsa kwa chinthu chogwira ntchito kumachitika m'matumbo aang'ono. Peak kugwiritsa ntchito mankhwalawa kumachitika mu 3 maola. Njira yosinthira acetylsalicylic acid imayamba m'chiwindi. Komanso, chinthuchi chimangopangika pang'ono. Zotsatira zake, mankhwala ocheperako pang'ono amapangidwa.
Njira yosinthira acetylsalicylic acid imayamba m'chiwindi.
Hafu ya moyo ndiyifupi - mphindi 15. Impso ndizomwe zimayambitsa izi. Komanso, zimadziwika kuti metabolites ya chinthu yogwira imasiya thupi pang'onopang'ono, mkati mwa maola atatu. Mphamvu ya antiplatelet imaperekedwa nthawi yomweyo, ngakhale mutatenga asidi ochepa acetylsalicylic. Imapitilira sabata 1.
Zomwe zimathandiza
Zisonyezo zakukhazikitsidwa kwa ndalamazi:
- kupewa chitukuko cha myocardial infarction, ngati pali zifukwa zoyipa zomwe zimathandizira mawonekedwe a matenda amtunduwu, mwachitsanzo, matenda a shuga, matenda oopsa, wodwala wokalamba, wonenepa kwambiri, ndi zina zambiri;
- kupewa pafupipafupi myocardial infarction;
- kupewa chitukuko cha ischemic stroke;
- ngozi yamitsempha;
- angina pectoris;
- kupewa kutsekeka kwamitsempha yamagazi ndi ma thrombus, kuchuluka kwa izi kumawonjezeka pakuchita opareshoni, komanso kungayambitse kuchitapo kanthu kwa opaleshoni: yamitsempha yamagazi ndi arteriovenous bypass grafting, endarterectomy and angioplasty of the carotid mitsempha;
- kupewa kukula kwa matenda limodzi ndi mtima kutsekeka: venous thrombosis, pulmonary embolism, etc.
Zisonyezo za kupezeka kwa mankhwala funso - venous thrombosis.
Contraindication
Zikhalidwe zingapo za pathological zimadziwika momwe zoletsedwa kugwiritsa ntchito wothandizirazi pakufunsidwa:
- zoipa zomwe munthu amachita pakumwa mankhwala acetylsalicylic acid, komanso mankhwala ena a gulu la NSAID okhala ndi zinthu zina;
- kukokoloka komwe kumayamba m'matumbo am'mimba kapena m'matumbo;
- magazi m'mimba;
- kuphwanya ntchito ya kupuma dongosolo bronchial mphumu, amene anayamba ndi salicylates;
- Fernand-Vidal wopitilira, wophatikizidwa ndi mawonekedwe amodzimodzi amatsitsi ku ASA, mphumu ya bronchial ndi sinus polyposis;
- diathesis, momwe mumakhala kutulutsidwa kwa magazi kupitirira kukhoma kwa zotengera, pamenepa, pamakhala kusintha kwa mtundu wamtundu wakunja wa chithunzi.
Ndi chisamaliro
Gulu la zoletsazi limaphatikizapo zotsutsana:
- mbiri yakukha magazi ndi njira zokoka kuchokera m'mimba;
- gout
- Hyperuricemia
- mphumu ya bronchial, yosagwirizana ndi kukhudzana ndi salicylates, komanso matenda ena opuma;
- hay fever;
- kuchepa kwa vitamini K ndi glucose-6-phosphate dehydrogenase;
- sinus polyposis;
- thupi lawo siligwirizana;
- munthawi yomweyo kugwiritsa ntchito metatrexate muyezo osapitirira 15 mg pa sabata.
Gulu la zoletsedwazo limaphatikizana ndi contraindication wachibale pazomwe zimachitika ndi mankhwala aliwonse.
Momwe mungatenge CardiASK
Mapiritsi amayenera kumwedwa ndi madzi, osafuna kutafuna, chifukwa kupera mankhwalawa patsogolo pake (mpaka atalowa m'matumbo) kumawopseza ndi zovuta zazikulu. Kudya sikukhudza mphamvu ya mankhwalawo komanso kagayidwe kake. Chithandizo chodziwika bwino cha matenda osiyanasiyana:
- popewa kulowetsedwa kwa myocardial ndi mikhalidwe yomwe imakhala ndi chiopsezo cha thrombosis kapena thromboembolism: 0.05-0.2 g patsiku, ndizovomerezeka kugwiritsa ntchito mankhwalawa tsiku lililonse, mwanjira iyi kuchuluka kwa ASA kumawonjezereka mpaka 0,3 g patsiku, woyamba piritsi limatafuna, lomwe limaletsa mwachangu zizindikiro zowopsa za matenda;
- pamaso pa zinthu zoyipa zomwe zimapangitsa kuti pakhale kulowerera kwa myocardial infarction, tengani 0,05-0.1 g patsiku, nthawi yomwe mankhwalawa amamwa tsiku lililonse, mlingo umawonjezereka mpaka 0,3 g;
- kupewa zina: (mobwerezabwereza myocardial infarction, angina pectoris, etc.): 0.05-0.3 g patsiku.
Mlingo wofanana, komanso nthawi yayitali ya chithandizo, umatsimikiziridwa poganizira zaka za wodwalayo, kupezeka kwa matenda ena ndi zomwe zimachitika m'thupi.
Mapiritsi ayenera kumwedwa ndi madzi, osafuna kutafuna.
Kumwa mankhwala a shuga
Chovomerezeka kugwiritsa ntchito wothandizirayo pakufunafuna kwake, komabe, mlingowo ungathe kufotokozedwanso, ngati pakufunika.
Zotsatira zoyipa za CardiASK
Choipa cha mankhwalawa ndimayendedwe ambiri osokoneza bongo omwe amachitika panthawi ya mankhwala. Kuchuluka kwawo ndi kuuma kwake kwakusiyana, komwe kumayendetsedwa ndi mtundu wa matenda komanso mkhalidwe wa wodwalayo.
Matumbo
Kutentha pa chifuwa, kusanza kutsokomola, zilonda zam'mimba za m'mimba zimayamwa, kugaya mafuta (mu milandu yayikulu), kupweteka pamimba.
Zotsatira zoyipa za CardiASK - kupweteka pamimba.
Hematopoietic ziwalo
Kutaya magazi kwa GI, kuchepa magazi.
Pakati mantha dongosolo
Mutu ndi chizungulire, kumva kuwonongeka.
Kuchokera ku kupuma
Bronchospasm.
Matupi omaliza
Quincke's edema, zizindikiro za urticaria (kuyabwa, zidzolo, kusokonezeka kwa khungu), rhinitis, kutupa kwa mphuno, kugunda kwa anaphylactic.
Zokhudza mphamvu pakuwongolera njira
Palibe zoletsa, komabe, ndibwino kusamala mukamayendetsa.
Ndikofunika kusamala mukamayendetsa.
Malangizo apadera
Ngati mlingo wa mankhwalawa umachulukidwa pafupipafupi, zovuta za odwala omwe ali ndi shuga zimawonjezera, mwachitsanzo, hypoglycemia imayamba.
Kuchulukitsa mlingo wa mankhwalawa kumawonjezera mwayi wokhetsa magazi.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Panthawi yobala mwana, ndizoletsedwa kupereka mankhwala omwe amafunsidwa mu 1 ndi 3 trimesters. Pa gawo loyambirira la kutenga pakati, chiopsezo cha kusintha kwamatenda mu minofu ya mwana wosabadwayo kumawonjezeka. M'miyezi yaposachedwa, pakhala pakuchepera kwa ntchito.
Mukamayamwitsa, sagwiritsanso ntchito mankhwalawo pofunsa. Izi ndichifukwa choti ma metabolites amalowa mkaka wa mayi.
CardiASK poika ana
Zosagwiritsidwa ntchito paubwana.
Gwiritsani ntchito mu ukalamba
Amaloledwa kupereka mankhwala. Kuchuluka kwa tsiku ndi tsiku kwa ASA sikusintha, koma kusamala ndikofunikira.
Amaloledwa kupereka mankhwalawa ukalamba.
The ntchito aimpso kuwonongeka
Sichigwiritsidwa ntchito poperewera ziwalo. Mankhwala amathandizidwa kuti ayambitse matenda a impso, mu nkhani iyi, kuyimitsidwa kwa impso kumayesedwa ndikuyang'aniridwa ndi dokotala kuyenera. Mtengo wa chizindikiro ichi suyenera kupitirira 30 ml / min.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Sichikuperekedwa chifukwa cholephera thupi. Mankhwalawa angagwiritsidwe ntchito ngati pali kusintha kwakung'ono ndi kwapakati pa chiwindi.
Cardiask Overdose
Ndi kuledzera m'malo ofooka, kumva kuwonongeka, nseru, kusanza, kusintha kwa chikumbumtima, chizungulire zitha kuchitika. Ngati mwana adamwa mankhwalawa, metabolic acidosis nthawi zambiri imayamba. Therapy pamilandu yotereyi cholinga chake ndicho kuthetseratu kuchuluka kwa zinthu zomwe zimagwiritsidwa ntchito, zomwe zimatheka chifukwa chochepetsera mlingo wa mankhwalawo kapena kusiya kwake, kutenga mpweya wothandizidwa, ndikupangitsa kuti magazi azikhala osasintha.
Ndi kuledzera mwa mawonekedwe ofatsa, makutu amawonongeka amatha.
Zizindikiro za kuledzera kwambiri:
- kuchuluka kwa kutentha kwa thupi mpaka kumagwira ntchito kwambiri;
- kupuma ntchito;
- kuphwanya mulingo wamadzi-electrolyte;
- kutsika kwa kupanikizika, kuletsa kwa mtima ntchito;
- hyper- kapena hypoglycemia;
- kutulutsa magazi m'mimba;
- kusamva kwa makutu;
- poizoni wa encephalopathy.
Zikatero, kugonekedwa kwa wodwala kumafunika.
Kuchita ndi mankhwala ena
Pogwiritsa ntchito munthawi yomweyo pogwiritsa ntchito njira zosiyanasiyana, zotsatira zake zingalimbikitsidwe kapena kuponderezedwa:
- mphamvu ya methotrexate imatheka;
- kukula kwa machitidwe a anticoagulants ukuwonjezeka;
- pali kuwonjezeka kwa zotsatira za thrombolytic, antiplatelet mankhwala;
- mulingo wa digoxin m'magazi ukuwonjezeka;
- mphamvu ya othandizira a hypoglycemic imatheka;
- ntchito ya zinthu zikuchokera uricosuric kukonzekera kumachepa;
- ubwino wokhala ndi ma salicylates umatsitsidwa ndikuwonetsa corticosteroids.
Kuyenderana ndi mowa
Mankhwala omwe amafunsidwa pomwe amamwa zakumwa zoledzeretsa amathandizira kuti aziwoneka ngati akutuluka magazi, ndikuwonjezera nthawi yawo.
Mankhwala omwe amafunsidwa, akumamwa zakumwa zoledzeretsa, amathandizira kuti magazi akuwoneka.
Analogi
Njira zothanirana zomwe zingalimbikitsidwe:
- Acetylsalicylic acid;
- Thromboass;
- Cardiomagnyl;
- Aspirin;
- Aspirin Cardio;
- Thrombopol, etc.
Kupita kwina mankhwala
Kuti mugule mankhwalawa, muyenera kugwiritsa ntchito mankhwala omwe simufunika.
Kodi ndingagule popanda kulandira mankhwala?
Pali mwayi wotere.
Mtengo wa CardiSC
Mtengo wapakati ku Russia ndi ma ruble 70-90.
Zosungidwa zamankhwala
Kutentha m'chipindacho sikuyenera kupitirira + 25 ° C.
Tsiku lotha ntchito
Kutalika kovomerezeka kwa mankhwalawa kuchokera tsiku lotulutsidwa ndi zaka ziwiri.
Wopanga
Canonfarm Production, Russia.
Ndemanga za Cardiask
Valeria Vasilievna, wazaka 55, Samara
Ndimakonda mankhwalawa, chifukwa ndi yabwino kumwa. Phalepo silifunikira kugawidwa, monga momwe zilili ndi Aspirin. Inde, ndipo mtengo wake ndi wabwino.
Veronika, wazaka 33, Omsk
Ndili ndi mavuto ndikutenga CardiASK: zimapangitsa phokoso m'makutu mwanga, ndikumva chizungulire. Dotolo adakhazikitsa njira - imwani mankhwalawa tsiku lililonse. Koma ndimayenera kuti ndichepetse mlingo chifukwa cha zovuta zomwe zimachitika.