Tebantin ndi gulu la mankhwala antiepileptic. Ili ndi anticonvulsant. Amagwiritsidwa ntchito makamaka pothandizira matenda a khunyu, concomitant pathologicalikhalidwe, ndi zovuta. Kuphatikiza apo, mankhwalawa amachotsanso zizindikiro zina, monga ululu. Mankhwala amakhudzidwa ndi zochita za thupi. Nthawi zambiri izi zimatanthawuza kukula kwa zotsatira zoyipa zambiri.
Dzinalo Losayenerana
Gabapentin (m'Chilatini - Gabapentin).
Tebantin ndi gulu la mankhwala antiepileptic.
ATX
N03AX12 Gabapentin
Kutulutsa mafomu ndi kapangidwe kake
Mankhwala amapangidwa monga mawonekedwe a makapisozi. Amakhala ndi chipolopolo cha gelatin, chodziwika ndi kapangidwe kolimba, mkati mwake mumakhala zinthu zofunikira. Pulogalamu yayikulu yomwe imawonetsa anticonvulsant ntchito ndi gabapentin. Mlingo wake umasiyanasiyana: 100, 300 ndi 400 mg (mu 1 kapisozi). Zinthu zochepa zomwe sizigwira ntchito:
- magnesium wakuba;
- talc;
- wowuma pregelatinized;
- lactose monohydrate.
Phukusili lili ndi matuza 5. Chiwerengero chonse cha makapisozi chikhoza kukhala chosiyana: ma 50 ndi 100 ma PC.
Mankhwala amapangidwa monga mawonekedwe a makapisozi.
Zotsatira za pharmacological
Kufanana kwa kapangidwe ka mankhwalawa ndi gamma-aminobutyric acid kumadziwika. Gawo lokangalalo limasinthidwa kwambiri. Izi zimachitika chifukwa chakuti ndi chinthu cha lipophilic. Ngakhale zofanana, mankhwalawo omwe amafunsidwawo samakhudzidwa ndikugwidwa kwa gamma-aminobutyric acid. Pali kuchepa kwa mphamvu ya Tebantin pa kagayidwe kazinthu izi.
Chimodzi mwa zochitika za pharmacological cha mankhwalawa ndi kuthekera kolumikizana ndi ma alpha2-gamma kugonjera kwa calcium tubules, zomwe zimatsimikiziridwa ndi maphunziro azachipatala. Mothandizidwa ndi Tebantin, kuyenda kwa mayendedwe a calcium kumalepheretsa. Zotsatira za njirayi ndi kuchepa kwamphamvu kwa kupweteka kwa neuropathic.
Nthawi yomweyo, mankhwalawa amathandiza kuchepetsa imfa ya ma neurons. Mothandizidwa ndi iye, kulimba kwa kapangidwe ka gamma-aminobutyric acid kumakulira. Kuphatikiza apo, pakukhazikitsa kwa Tebantin, kuletsa kumasulidwa kwa ma neurotransmitters a gulu la monoamine kumadziwika. Zinthu zonsezi zimayendera limodzi ndi kuchepa kwakali kwa kupweteka kwa neuropathic.
Ubwino wa mankhwala omwe mukufunsawa ndikulephera kuyanjana ndi ma receptor a mankhwala ena omwe amagwiritsidwa ntchito pochiza khunyu. Kuphatikiza apo, kusiyana kwa Tebantin ndikusowa kwa mwayi wowonekera kwa sodium tubules.
Pharmacokinetics
Pamene chinthu chachikulu chikalowa m'mimba, chimbudzi chachikulu chimadziwika. Ngati mankhwalawa agwiritsidwa ntchito koyamba, kuchuluka kwa ntchito kumawonjezeka pang'onopang'ono ndikufikira pakapita maola atatu. Ndi kugwiritsa ntchito mankhwalawa mobwerezabwereza, kuchuluka kwa chidwi cha omwe amagwira ntchito kumafikiridwa mwachangu - 1 ora.
Kuchotsa kwathunthu kwa chigawo chogwira ntchito m'thupi (makamaka kuchokera m'madzi a m'magazi) kumatheka kudzera mwa hemodialysis.
Chimodzi mwa mankhwalawa chomwe chikuphatikizidwa ndi ubale womwe ulipo pakati pa kuchuluka kwa zomwe zimagwiritsidwa ntchito ndi wodwala komanso bioavailability. Chizindikiro ichi chimachepa ndi kuwonjezeka kwa mlingo wa mankhwalawa. Mtheradi wa bioavailability wa mankhwalawa ndi 60%.
Pulogalamu yayikulu yogwira sikugwirizana ndi mapuloteni a plasma. Kuchulukitsidwa kwa gabapentin mu madzi ammagazi sikupitirira 20% ya madzi a m'magazi. Nthawi yotsiriza ya phata yayikulu ndi maola 5-7. Kufunika kwa chizindikirocho ndikokhazikika ndipo sikudalira kuchuluka kwa mankhwalawo.
Chinthu chinanso cha gabapentin ndi chimbudzi chosasinthika. Kuchotsa kwathunthu kwa chigawo chogwira ntchito m'thupi (makamaka kuchokera m'madzi a m'magazi) kumatheka kudzera mwa hemodialysis.
Kodi chimagwiritsidwa ntchito ndi chiyani?
Ndi bwino kugwiritsa ntchito mankhwalawa mafunso awa:
- mikhalidwe yopweteketsa mtima (yokhala ndi generalization), yotsogola ndi zovuta zamagalimoto, zamaganizo, zamagetsi;
- kupweteka kwa neuropathic kwa odwala azaka zopitilira 18.
Amadziwika kuti popereka mankhwala kuti athetse zofooka, msambo wa wodwalayo umawaganiziranso. Chifukwa chake, achikulire ndi ana kuyambira zaka 12 akulimbikitsidwa kugwiritsa ntchito chida ichi limodzi ndi monotherapy, komanso ngati gawo la chithandizo chovuta. Pamafunika kuthetseratu zizindikiro za vuto lakelo kwa odwala omwe ali ndi zaka 3 mpaka 12, kugwiritsa ntchito Tebantin ndikotheka pokhapokha ndimankhwala ena.
Ndi bwino kugwiritsa ntchito mankhwalawa pofunsa ululu wa neuropathic odwala omwe ali ndi zaka zopitilira 18.
Contraindication
Matenda a m'matumbo amadziwika omwe mankhwalawa sanadziwike. Izi zikuphatikiza:
- Zomwe zimachitika munthu akamalowa m'thupi;
- kapamba mu gawo pachimake;
- Zotsatira zoyipa za lactose, kuperewera kwa lactase, malabsorption a glucose-galactose, zomwe zimachitika chifukwa cha mankhwala a lactose.
Ndi chisamaliro
Odwala aimpso kulephera amafuna kusintha kusintha kwa yogwira pawiri. Izi ndichifukwa choti ndi matenda oterewa, kutulutsa kwa chinthu chachikulu kumachepetsedwa kwambiri, kumatha kukhala maola 52.
A pathological mkhalidwe womwe mankhwalawo wofunsidwa sanafotokozedwe ndi kapamba mu gawo la pachimake.
Kodi mutenge bwanji Tebantin?
Kudya sikukhudza mayamwidwe ndi ntchito ya mankhwala. Makapisozi sayenera kutafunidwa, chifukwa cha izi, zotsatira za Tebantin zitha kuchuluka.
Kutalika kochepa pakati pa Mlingo wa mankhwalawa ndi maola 12. Malangizo ogwiritsira ntchito zosiyanasiyana pathological:
- Kukakamira pang'ono. Mlingo wa akulu ndi ana ndi 900-1200 mg patsiku. Yambirani maphunziro anu ndi kuchuluka kochepa (300 mg). Ana a zaka 3 mpaka 12 amatchulidwa mankhwalawa, kukumbukira thupi. Chiwerengero chokwanira cha mankhwalawa chimawerengedwa kuti chimakhala cha 25-25 mg / tsiku. Pankhaniyi, mankhwalawa amatchulidwa limodzi ndi mankhwala ena antiepileptic. Mlingo wa tsiku ndi tsiku uyenera kugawidwa mu Mlingo wa 2-3.
- Mankhwalawa neuropathic ululu, kuchuluka kwa yogwira mankhwala amatsimikiza payekha. Mulingo woyenera kwambiri wothandizira mu nkhaniyi ndi 3600 mg / tsiku. Njira ya mankhwalawa imayamba ndi kuchuluka kwa zinthu zomwe zimagwira (300 mg). Mlingo wa tsiku ndi tsiku umagawidwa mu Mlingo wa 2-3.
Mlingo wa odwala omwe ali ndi matenda ashuga
Tiyenera kudziwa kuti mankhwalawa amakhudza kuchuluka kwa shuga m'thupi. Pazifukwa izi, kusintha kwamphamvu kwa piritsi yogwira ntchito ndikofunikira. Kuchuluka kwa mankhwalawa kwa odwala omwe ali ndi matenda a shuga amakhazikika.
Kuchuluka kwa mankhwalawa kwa odwala omwe ali ndi matenda a shuga amakhazikika.
Kutenga nthawi yayitali bwanji?
Kutalika kwa maphunzirowa kumasiyanasiyana malinga ndi zinthu zingapo: zaka za wodwalayo, chithunzi cha matenda, kuwopsa kwa zizindikiro, mtundu wa matenda, matenda omwe amagwirizana ndi zomwe zimapangitsa chithandiziro cha ntchito. Komabe, zimadziwika kuti nthawi zambiri, nthawi yayitali ya chithandizo ndi masabata 1-4. Komanso, mpumulowo umadza pakatha masiku 1-2 chiyambireni chithandizo.
Zotsatira zoyipa
Choyipa chachikulu cha mankhwalawa ndi kuchuluka kwakukulu komwe kumachitika. Kukula kwa zotsatira zoyipa zimatengera mkhalidwe wamthupi panthawi yamankhwala.
Matumbo
Zizindikiro za matenda ammimba:
- kupweteka pamimba;
- kukulira kapena, kukulirakulira;
- kusintha kwa chopondapo;
- matenda a anorexia;
- chisangalalo;
- matenda a mano;
- kuwonongeka kwa chiwindi (hepatitis);
- jaundice
- kapamba
Chizindikiro cha matenda ammimba ndi jaundice.
Pa khungu
Maonekedwe a totupa amadziwika.
Hematopoietic ziwalo
Pathologies monga thrombocytopenia, leukopenia amakula.
Pakati mantha dongosolo
Pali kuphwanya chikhalidwe cha psychoemotional (kukhumudwa, kuwonongeka kwamanjenje, ndi zina), mawonekedwe a chizungulire komanso kupweteka kwa mutu. Nthawi zina nthabwala, kunjenjemera kumachitika, amnesia ikhoza kukhala. Pali kuphwanya kwa kulingalira (kusokonezeka kumadziwonetsera nokha), kudzimva (paresthesia), kugona, ntchito yowonetsera.
Kuchokera ku kupuma
Matenda ndi zizindikiro zotsatirazi zimayamba:
- rhinitis;
- pharyngitis.
Kuphatikiza pa kutenga mankhwala ena antiepileptic, chibayo chimayamba ndipo chifuwa chimayamba.
Kuchokera ku genitourinary system
Pali kuphwanya kwamkodzo kwamkodzo, ntchito yogonana yamphongo, kuchulukitsa matenda a impso, gynecomastia akufalikira. Tizilombo tosiyanasiyana titha kukula.
Kuchokera ku genitourinary system, gynecomastia amakula.
Kuchokera pamtima
Nthawi zina minyewa yosalala imamasuka m'mitsempha yamagazi, yomwe imawonongeka molakwika pakugwira ntchito kwa mtima. Nthawi yomweyo, pali kuwonjezeka kwa kuthamanga kwa magazi. Kuphatikiza apo, mankhwalawa amakhudza kugunda kwa mtima.
Kuchokera ku minculoskeletal system
Mankhwalawa antiepileptic mankhwala, zotsatirazi pathological zikhalidwe: arthralgia, myalgia, fractures amakhala pafupipafupi.
Matupi omaliza
Kuyabwa, zidzolo, ndi zizindikiro za urticaria zimadziwika. Nthawi zambiri, kutentha kumakwera, angioedema kumachitika. Mankhwalawa antiepileptic mankhwala, pali mwayi wopanga milingo yodziwika bwino ya erythema.
Zizindikiro za urticaria zimadziwika.
Malangizo apadera
Palibe pathologies, njira yowunika kuchuluka kwa mankhwalawa mu plasma siigwiritsidwa ntchito. Kwa odwala omwe ali ndi shuga yotsimikizika, kuyang'anira shuga ndikulimbikitsidwa. Pokonza matenda owopsa, kugwiritsa ntchito mankhwalawa kuyimitsidwa.
Sizoletsedwa kuti mwadzidzidzi mugule mankhwalawo. Mlingo umachepetsedwa pang'onopang'ono (mkati mwa sabata 1). Ngati mwatsimikiza mwadzidzidzi mankhwalawo atha kufunsidwa, khunyu ikhoza kuchitika. Ngati zizindikiro za bongo zimachitika, mankhwalawo amasiya.
Nthawi zambiri, achire mlingo wa mankhwalawa ukuwonjezeka ndi 300 mg nthawi iliyonse. Chovomerezeka kwa odwala omwe apatsitsidwa chiwalo china kuti awonjezere kuchuluka kwa mankhwalawa tsiku lililonse ndi 100 mg.
Amakhulupirira kuti mankhwalawo omwe amafunsidwa ndi mankhwala. Uku ndikulakwitsa, chifukwa Tebantin ali ndi malingaliro osiyana pochita, siwowonjezera.
Ngati mwatsimikiza mwadzidzidzi mankhwalawo atha kufunsidwa, khunyu ikhoza kuchitika.
Zokhudza mphamvu pakuwongolera njira
Mankhwalawa ali ndi zotsatira zoyipa zamagetsi, mtima, ziwalo zam'malingaliro (masomphenya, kumva). Zimatha kupangitsa kuti pakhale zovuta zazikulu. Pachifukwa ichi, muyenera kukana kuyendetsa magalimoto mpaka maphunziro atamalizidwa.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Mankhwala ali osavomerezeka kuti mugwiritse ntchito pakhungu. Izi ndichifukwa chakusowa kwa chidziwitso pa mwana wosabadwayo. Komabe, ngati pakufunika thandizo mwachangu, mankhwala amathandizidwabe ngati phindu limaposa kuvulaza komwe kungachitike.
Poganizira kuti, poyamwitsa, chinthu chogwira ntchito chinafika mkaka wa mayi, kugwiritsa ntchito mankhwalawa kuyenera kukhala kochepa. Amawonetsera mkaka pokhapokha ngati phindu limapweteketsa mwana.
Tebantin adalembedwa kuti azimuwonjezera pokhapokha ngati phindu limaposa kuvulaza kwa mwanayo.
Kupangira Tebantin kwa ana
Mankhwalawa saloledwa kugwiritsidwa ntchito pochiza odwala omwe sanakwanitse zaka 3. Kwa odwala omwe ali ndi zaka 3 mpaka 12, mankhwalawo atha kutumikiridwa ngati gawo la zovuta, chifukwa mankhwalawa ndiwopsa.
Gwiritsani ntchito mu ukalamba
Popeza kuti chimbudzi cha mankhwala othandizira kuchokera ku gulu la odwala chikuchepa, mankhwalawa amalembedwa payekhapayekha ndikuganizira chilolezo cha creatinine.
Mukalamba, mankhwalawa amayikidwa payekhapayekha ndikuganizira chilolezo cha creatinine.
Bongo
Palibe milandu yovuta ya kuledzera kwa thupi mukamagwiritsa ntchito mankhwala osokoneza bongo (ngakhale mutabweretsa 49 g). Komabe, kuoneka kwa zoyipa zosakhudzidwa ndimomwe mulingo wambiri woyenera umalandira:
- mavuto ndi malankhulidwe;
- Chizungulire
- kuphwanya chopondapo (m'mimba);
- ulesi;
- kugona
- kuwonongeka kwamaso (kawiri m'maso).
Ndi kuledzera kwa odwala aimpso kulephera, hemodialysis ndi mankhwala. Nthawi zina, chithandizo chamankhwala chimasonyezedwa.
Maonekedwe amisala osokoneza bongo omwe ali ndi kuchuluka kwa mankhwalawa amadziwika: kuwonongeka kwa mawonekedwe (kuwirikiza kawiri m'maso).
Kuchita ndi mankhwala ena
Mukamapereka mankhwala omwe amafunsidwa, kuthandizira komanso chitetezo kumayesedwa pamene mukugwiritsa ntchito mankhwala ena.
Kuyenderana ndi mowa
Zakumwa zokhala ndi zakumwa zoledzeretsa zimathandizanso kuyipa kwamankhwala.
Kuphatikiza kophatikizidwa
Maantacidid amathandizira kuchepetsa kukhudzana kwa mankhwalawa.
Osavomerezeka kuphatikiza
Ndikwabwino kuti musagwiritse ntchito Morphine mukamamwa Tebantin.
Ndikwabwino kuti musagwiritse ntchito Morphine mukamamwa Tebantin.
Kuphatikiza komwe kumafunikira kusamala
Kugwiritsa ntchito mankhwalawa pofunsa ndi mankhwala ena antiepileptic ndizovomerezeka. Amaloledwa kugwiritsa ntchito mankhwalawa ndi cimetidine, probenecid.
Analogi
Mutha kugwiritsa ntchito ndalamazi mosiyanasiyana: mapiritsi, makapisozi. Magulu Othandizira a Tebantin:
- Nyimbo
- Neurontin;
- Gabagamm
- Gabapentin.
Kupita kwina mankhwala
Mankhwala ndi mankhwala.
Mtengo wa Tebantin
Mtengo umasiyanasiyana kuchokera ku 700 mpaka 1500 rubles.
Zosungidwa zamankhwala
Kutentha kovomerezeka komwe malo omwe mankhwalawo amasungidwa: mpaka + 25 ° C.
Tsiku lotha ntchito
Mankhwalawa amagwiritsidwa ntchito zaka 5 kuyambira tsiku lotulutsidwa.
Wopanga
"Gideon Richter", waku Hungary.
Umboni wa madokotala ndi odwala za Tebantin
Tikhonov I.V., vertebrologist, wazaka 35, Kazan.
Ndinafunika kupatsa mankhwala mankhwala a ululu wa neuropathic. Zotsatira zake zimakhala zabwino, mpumulo umabwera tsiku loyamba. Malinga ndi ndemanga za odwala, nditha kuweruza zomwe zimachitika pafupipafupi kuchokera ku dongosolo lalikulu lamanjenje.
Galina, wazaka 38, Pskov.
Mankhwalawa adapangidwa kuti ayambitse kupindika kwa msana (panali kupweteka kwambiri). Anamugwira monga mwa chiwembu. Zotsatira zoyipa sizinachitike. Komanso, mlingo wake unali waukulu kwambiri - 2535 mg patsiku.
Veronica, wazaka 45, Astrakhan.
Mankhwalawa adalembera mwana wanga. Zaka zake ndi zazing'ono (zaka 7), motero, mankhwalawo anali ocheperako (malinga ndi kulemera kwa thupi). Mothandizidwa ndi Tebantin, zidatha kupewa kuwoneka ngati agwidwa, komanso kuonjezera kusiyana pakati pawo.
