Lisinopa Mankhwala amaletsa stroke, angina pectoris, kulephera kwa mtima.
Dzinalo Losayenerana
Lisinopril.
ATX
О А..
Kutulutsa mafomu ndi kapangidwe kake
Mankhwalawa amapangidwa ngati mapiritsi okhala ndi mawonekedwe ozungulira. Zomwe zimagwira ntchito yomwe ili gawo lake ndi lisinopril dihydrate; Zowonjezera zina zofunika kuti mapiritsiwo azikhala wozungulira.
Lisinopa
Othandizira ndi:
- calcium dihydrogen phosphate;
- wowuma;
- kunenepa.
Zowonjezera zimakhudzana ndi ziwalo ndi minofu, koma osasintha bioavailability wa mankhwalawa.
Zotsatira za pharmacological
Mankhwalawa amawonjezera chiyembekezo chokhala ndi moyo, amalepheretsa kukula kwa hypertrophy yamanzere yamitsempha, amachepetsa kuchuluka kwa mapuloteni mumkodzo, samayambitsa hypoglycemia.
Pharmacokinetics
Zamankhwala pazamankhwala ndizofunikira kuchipatala:
- mkulu bioavailability;
- kudziyimira pawokha, chifukwa mankhwalawa ndiwogwira ntchito;
- nthawi ya zoletsa za ACE;
- kuthetsa.
Kuphatikiza apo, mankhwalawa sakukhudzidwa ndi metabolism, chifukwa lipophilicity yake ndiyotsika, imathandizira kukulitsa kwamitsempha yamagazi, yotulutsidwa mu mkodzo. Bioavailability ndi 50% ndipo sasintha mothandizidwa ndi chakudya.
Mankhwalawa amapangidwa ngati mapiritsi okhala ndi mawonekedwe ozungulira.
Mankhwala samatupa m'chiwindi, mosiyana ndi ma vasodilator ena. Kuzunzidwa kwakukulu kwambiri mu seramu kumawonedwa patatha maola 7 mutachotsedwa kwa mankhwalawa.
Popeza kagayidwe kachakudya mu chiwindi amalola ntchito yogwira ntchito odwala ndi matenda a hepatobiliary dongosolo.
Zomwe amachiritsa
Mapiritsi a antihypertensive ndi mankhwala okhala mzere woyamba wochizira matenda osakwanira a myocardial, limodzi ndi vuto lakumanzere kwamitsempha.
Mankhwalawa ali ndi zotsatirazi mthupi:
- amathandiza homeostasis;
- ali ndi antioxidant ndi mtima;
- zimasokoneza myocardial ischemia.
Zisonyezo zakukhazikitsidwa kwa mankhwalawa ndi:
- matenda oopsa II-III;
- pachimake myocardial infarction mu gawo la kukhazikika kwa hemodynamics;
- kutsekeka kwa nthambi za mtengo Wake;
- kuphwanya systolic ntchito yamanzere yamitsempha yamagazi;
- angina pectoris;
- lipid yapamwamba;
- matenda a shuga;
- kupewa kuphatikiza kwa magazi kuundana ndi magazi.
Mankhwala amagwiritsidwa ntchito ngati gawo limodzi la mankhwala othandizira kuphatikiza ndi okodzetsa. Mapiritsi amalembedwa asymptomatic lamanzere yamitsempha yamavuto.
Kwa kupewa kwachiwiri kwa mtima ndi matenda a mtima, mankhwalawa amaperekedwa kwa odwala omwe ali ndi mbiri ya kulowetsedwa kwa myocardial, akuvutika ndi kusungika kwa mtima wamitsempha, pamodzi ndi kusokonekera kwa systolic.
Odwala omwe ali ndi matenda oopsa kwambiri kuposa zaka 65, zinthu zomwe zimagwira zimakhudza impso.
Contraindication
Mankhwala sinafotokozeredwe ngati wodwalayo wapanga njira zotsatirazi:
- ochepa hypotension;
- anaphylactic mantha;
- potaziyamu yayikulu m'magazi;
- matenda a minofu;
- matenda a chiwindi ndi impso (kuphatikizapo matenda adrenal osakwanira);
- gout
- kuwonongeka kwa m'mafupa;
- aimpso mtsempha wamagazi stenosis;
- kuchepa kwa chithokomiro;
- urticaria.
Ndi matenda a chiwindi, mankhwalawa saikidwa mankhwala.
Mwa munthu wokalamba, mukamagwiritsa ntchito mlingo waukulu wa mankhwalawa, hypotension imayamba, chikhalidwe chaumoyo chimakulirakulira, ndikuwonekeratu kuti akupha kumawonjezeka.
Komanso, mankhwalawa saikidwa kwa odwala tachycardia, edema ndi matenda a bronchopulmonary system. Wodwala yemwe watenga mlingo waukulu wa mankhwalawa amadandaula chifukwa chokhala ndi thanzi labwino, chizungulire, kufooka, kugona, komanso kukomoka.
Wodwala akakhala ndi mavuto ndi maovala amtima kapena kuvulala kwa ubongo ndi msana, ndiye kuti magazi amatsika kwambiri atatenga vasodilator.
Momwe mungatengere Lisinopril 10
Mlingo wa mankhwalawa ndiudokotala. Vasodilator amagwiritsidwa ntchito ngati monotherapy, ndikuwapangidwanso monga gawo la chithandizo chokwanira ndi mankhwala ena.
Antihypertgency imatengedwa nthawi yomweyo.
Mlingo wa mankhwalawa ndiudokotala.
Ndi matenda a renovascular Hypertension
Mankhwalawa amagwira ntchito yotsitsa plasma renin. Kwa odwala omwe ali ndi zaka zopitilira 60, mankhwalawa tsiku lililonse a 2,5 mpaka 40 akulimbikitsidwa. Nthawi zambiri, dokotala amatiuza kumwa mapiritsi a 5 mg / tsiku.
Njira zochizira matenda oopsa ndi munthu payekha, kutengera kuchuluka kwa kuthamanga kwa magazi. Palibe mphamvu, mlingo wa mankhwalawa umakulitsidwa mpaka 10-15 mg. Mankhwala a antihypertensive amachitika ndi cholinga chokonza kuthamanga kwa magazi, kukwaniritsa mulingo woyenera wa 140/90 mm RT. Art. (mwa anthu omwe ali ndi matenda ashuga).
Mapiritsi amayikidwa limodzi ndi beta blocker komanso okodzetsa.
Ndi kulephera kwa aimpso
Mu kachitidwe kachipatala, mankhwalawa adapangidwa kuti achepetse kuchuluka kwa ma capillaries mu glomeruli, kuchepetsa kukakamiza ndi kuwonetsa kwa mapuloteni ndi mkodzo. Kulephera kwamkati ndi maziko osankha mtundu wa mankhwalawa.
Kulephera kwamkati ndi maziko osankha mtundu wa mankhwalawa.
Mu zovuta zovuta matendawa, kuchuluka kwa achire othandizira ndi 5-10 mg 1 nthawi patsiku. Odwala okhala ndi creatinine chilolezo chochepera 80 ml / mphindi, kuphatikiza kwa othandizira ena ndi okodzetsa kumagwiritsidwa ntchito kuchuluka kwa 10 mg / 125 mg kamodzi patsiku.
Pachimake myocardial infaration
The mankhwala zotchulidwa mu tsiku loyamba la chitukuko cha pachimake matenda. Mlingo wa mankhwalawa ndi 5-10 mg. Wodwalayo amamwa mankhwalawa kwa milungu itatu. Mankhwala atatha, ntchito yamanzere yamitsempha yamagazi imakhala bwino.
Zochizira myocardial infarction, wothandizirana ndi angiopertgency amamuika ngati gawo la mankhwala osakanikirana ndi acetylsalicylic acid.
Kumwa mankhwala a shuga
Mankhwala amalimbikitsidwa kwa odwala omwe ali ndi insulin-II yodwala matenda a shuga. Mapiritsi amakhala ndi kamvekedwe ka misempha, magazi ochepa. Wodwala ndi mankhwala 10 mg mapiritsi.
Mankhwala amalimbikitsidwa kwa odwala omwe ali ndi insulin-II yodwala matenda a shuga.
Mankhwala ali ndi tanthauzo lokhalitsa. Poyerekeza ndi maziko a matenda a shuga, amachepetsa chiopsezo chokhala ndi matenda am'mimba, amachepetsa kusintha kwa dziko la prediabetesic kukhala matenda ashuga. Mlingo wa tsiku ndi tsiku wa mankhwalawa ungagawidwe mu 2 Mlingo: m'mawa ndi madzulo, piritsi.
Zotsatira zoyipa
Vasodilator imayambitsa zotsatira zosafunikira zomwe zimakhala zofatsa komanso zosakhalitsa.
Matumbo
Kumwa mapiritsi a kupsinjika kwa zaka zingapo wodwala wokhala ndi zizolowezi zoyipa ndikofunikira kwambiri pakupanga gastritis. Mavuto amawoneka ndi nseru, kusanza, kusasangalala ndi m'mimba, kutsegula m'mimba, ndikusintha kukoma.
Nthawi zambiri mumakhala:
- kapamba
- hepatitis;
- jaundice.
Wodwalayo amadandaula za kuwoneka kuti akuvutika atatha kudya, kutentha kwadzuwa.
Kuchokera m'matumbo, zovuta zingapo zimachitika, mwachitsanzo, kutentha kwa mtima.
Hematopoietic ziwalo
Nthawi zambiri atatha kumwa mankhwalawa, wodwalayo amawona mawonekedwe amawu ake.
Zotsatira zoyipa za mankhwala pamagazi zimatsagana ndi:
- leukopenia;
- thrombocytopenia;
- kuchepa kwakukulu kwa agranulocytes ndi hemoglobin.
Pakati mantha dongosolo
Zizindikiro zotsatirazi zimayendera limodzi ndi zovuta za wodwala:
- idachepetsa chidwi;
- chisokonezo cha chikumbumtima;
- kugona
- mutu
- kupendekera kwakomoka kwa milomo ndi miyendo;
- kusinthasintha kwa magazi;
- paresthesia.
Kugona ndi chimodzi mwazotsatira zoyambitsa kumwa mankhwalawa pakatikati wamanjenje.
Kumwa mowa kwambiri, kugwira ntchito mopitirira muyeso, kuwotchera msana kumayambitsa kutsika kwa mitsempha, komanso kulandira chithandizo cha vasodilator kumawonjezera vuto la wodwalayo.
Kuchokera ku kupuma
Bronchospasm ndi vuto lalikulu lomwe limachitika mutatha kumwa mapiritsi a munthu oopsa. Wodwala amadwala chifukwa chosowa mpweya, kuopa kufa, palpitations, chifuwa chowuma. Munjira zam'mlengalenga, ntchofu amadziunjikira, mwayi wokhala ndi edema yocheperako umakulira.
Wodwalayo amadandaula za kupukutira kowuma, kupuma kwake, ndipo minyewa yapakhosi yotupa imatupa.
Pa khungu
Mutatha kumwa mankhwalawa, khungu lotsatira lingayambike:
- urticaria;
- angioedema;
- zotupa pakhungu;
- kuyabwa
- malungo.
Mutatha kumwa mankhwalawa, mawonetseredwe a thupi lawo ndi otheka: kuyabwa, zotupa pakhungu.
Khungu losakanizika limatha kuphimbidwa ndi thovu yaying'ono. Zilonda zimachitika pachilichonse cha thupi: kumbuyo kwa mutu, khosi, kutsogolo kwa ntchafu, maondo.
Kuchokera ku genitourinary system
Mankhwala amakhudza nthawi ya kutupa mkati mwa kwamikodzo chiwalo.
Wodwalayo amatulutsa zotsatirazi zamikhalidwe:
- cystitis
- pyelonephritis;
- pachimake aimpso kulephera.
Kukanika kwa impso kumatsogolera pakudzipweteka thupi.
Dongosolo la Endocrine
Zilonda zotsatirazi ndizambiri:
- kuchepa kwa ntchito ya endocrine limba;
- chithokomiro chithokomiro.
Wodwalayo amadandaula za mavuto:
- kutopa
- kutaya mphamvu;
- kugona
- kudzala;
- kutupa
- kudzimbidwa.
Pambuyo kumwa mankhwalawa, wodwalayo amatha kudandaula kuti akudzimbidwa.
Matenda a shuga a II angayambike. Matendawa amakula msanga.
Mwa amuna, potency imalephera.
Malangizo apadera
Ndikofunikira kuthana ndi ntchito ya impso, kumwa madzi okwanira musanamwe mankhwalawa.
Zokhudza mphamvu pakuwongolera njira
Mukamamwa mapiritsi panthawi yotentha, zopinga zimatha kuyambika, pomwe chidwi cha anthu chimakulirakulira. Chifukwa chake, mankhwalawa saloledwa kwa odwala omwe akuchita ntchito yoopsa.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Chogwiritsidwacho chimakhala ndi zotsutsana ndi maphunzirowa komanso zotsatira za kutenga pakati.
Chogwiritsidwacho chimakhala ndi zotsutsana ndi maphunzirowa komanso zotsatira za kutenga pakati.
Palibe maphunziro omwe adachitidwa kuti akhazikitse kuchuluka kwa zoopsa panthawi yoyamwitsa.
Kulemba Lisinopril kwa ana 10
Mankhwalawa amadziwitsidwa ngati kulibe contraindication komanso kuganizira zaka za mwana. Wodwalayo akulimbikitsidwa kuchepa kwa mankhwala a antihypertensive, makamaka mankhwala osagwirizana ndi ndale. Wodwala matenda a pyelonephritis amasankhidwa ndi chithandizo chokwanira.
Gwiritsani ntchito mu ukalamba
Odwala omwe ali ndi matenda oopsa, mankhwalawa amaperekedwa pa 10 mg / tsiku. Ndi matenda oopsa a digiri yoyamba ya zovuta, mankhwalawa amalola kuti akhale ndi matenda a diastolic.
Mphamvu ya mankhwalawa imatha maora 24 mukamamwa 1 nthawi patsiku. AnCE inhibitor imadziwika ndi kugwira ntchito kwambiri mwa okalamba.
AnCE inhibitor imadziwika ndi kugwira ntchito kwambiri mwa okalamba.
The ntchito aimpso kuwonongeka
Mankhwala amatengedwa pakamwa kamodzi pa tsiku, mosasamala kanthu za kudya. Ngati aimpso ntchito, a otsika koyamba mlingo zotchulidwa: 2,5-5 mg / tsiku. Nthawi ya chithandizo, ndikofunikira kuwongolera ntchito ya kwamikodzo, ndende ya potaziyamu mu seramu yamagazi.
Mlingo woyambirira umatsimikiziridwa kutengera chilolezo cha creatinine. Ngati mtengo wake uli 10-30 ml / mphindi, ndiye kuti 2,5-5 mg wa mankhwala oopsa amalimbikitsidwa kuti azitha kuchira.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Zovomerezeka motsutsana ndi maziko a matenda a chiwindi. Zowonongeka zamagulu sizikhudza pharmacokinetics yamankhwala. Kumwa mankhwala pa 10 mg ya patsiku kumachepetsa kuthamanga kwa magazi mu 53% ya odwala.
Odwala omwe ali ndi steatosis ndi matenda ena okhudzana ndi mitsempha sayanjana ndi mankhwala a antihypertensive. Mlingo wa mankhwalawa umachulukitsa kapena hypothiazide imawonjezeredwa.
Odwala omwe ali ndi steatosis ndi matenda ena okhudzana ndi mitsempha sayanjana ndi mankhwala a antihypertensive.
Bongo
Odwala aukalamba komanso osakhazikika, mankhwalawa matenda a mtima osakhazikika, zizindikiro zimawonekera, zikusonyeza kuchuluka kwa antihypertensive mankhwala.
Mankhwala wokhazikika mu mlingo waukulu umayambitsa zizindikiro za kusakwanira kwa ziwalo zambiri, kusinthasintha kwa mtima.
Wodwalayo amakhala ndi zotsatirazi:
- kusowa kwa mpweya;
- kupuma movutikira pakulimbitsa thupi;
- kutsokomola;
- tachycardia;
- arrhythmia;
- kutopa
- Chizungulire
- tinnitus;
- wokongola
- kusowa tulo
- kukhumudwa
Chifukwa cha bongo, chizungulire chitha kuchitika.
Kuchita ndi mankhwala ena
Mankhwala ndi okodzetsa amagwiritsidwa ntchito munthawi yomweyo amayambitsa hypercalcemia, zovuta zowopsa zimachitika - kumangidwa kwamtima.
Zotsatira za kumwa mankhwalawa zimawonjezeka ngati zimakhazikitsidwa ndi beta-blockers, thiazides, calcium blockers.
Mankhwala othandizira zilonda zam'mimba amachepetsa kuyamwa kwa ACE inhibitor m'mimba.
Kuyenderana ndi mowa
Kugwiritsa ntchito mosakanikirana ndi zakumwa zoledzeretsa zomwe zimapangitsa kuti munthu azigwira ntchito mopitirira muyeso ndikukula kwa zizindikiro zomwe zimakhala zowopsa pamoyo wa wodwalayo.
Analogi
Hypertension ndi matenda oopsa. Mitundu ya jini imagwiritsidwa ntchito pochiza:
- Diroton;
- Dapril;
- Sinopril;
- Lizonorm;
- Lisinotone;
- Captopril;
- Corfid.
Diroton ndi amodzi mwa fanizo la mankhwalawa.
Mankhwala osokoneza bongo ali ndi antihypertensive effect.
Maholide a Lisinopril 10 ochokera ku malo ogulitsa mankhwala
Kuti mugule mankhwala, muyenera kulandira mankhwala kuchokera kwa dokotala.
Kodi ndingagule popanda kulandira mankhwala?
Pazifukwa zapadera, mutha kugula mankhwalawo kuchokera kwa wogulitsa mankhwala, ndikufotokozera chifukwa choperewera mankhwala.
Zochuluka motani
Mtengo umasiyanasiyana kutengera wopanga.
Mankhwala a kampani ya ALSI-Pharma amatenga ma ruble 17. pa paketi 30 30 ma PC. Mtengo kuchokera kwa Ratiopharm wopanga - 330 rubles. 30 ma PC.
Zosungidwa zamankhwala
Mchipinda chopanda khungu kutentha kwa chipinda pamalo amdima.
Sungani phukusi la cell mu kutentha kwa chipinda pamalo amdima.
Tsiku lotha ntchito
Zaka 4
Wopanga Lisinopril 10
Mankhwalawa amapangidwa ndi opanga angapo:
- Teva
- Nyenyezi;
- Ratiopharm ndi ena
Ndemanga za Lisinopril 10
Madokotala ndi ogula amayankha bwino za mankhwalawo.
Madokotala
Irina, katswiri wamtima, Novorossiysk
Ndikupangira mankhwala ochizira matenda oopsa. Ndisanayambe mankhwala, ndimazindikira ntchito ya impso. Ndimapereka mankhwala okwanira 10 mg kamodzi patsiku ngati gawo la chithandizo chokwanira.
Valentin, dokotala wamtima, Moscow
Ndimapereka mankhwala mankhwalawa matenda oopsa. Mukamamwa, ndikofunikira kutsatira malingaliro onse, monga Mankhwala osokoneza bongo amatha kuyambitsa mavuto.
Odwala
Olga, 62 g, Moscow
Ndili ndi matenda oopsa a digiri ya III, kutupa kwambiri, kufupika, palpitations. Dotolo adapereka mankhwala kuti akakamizidwe kuphatikiza Indapamide.Ndimamwa mapiritsi nditatha kudya 5 mg m'mawa ndi madzulo. Zinthu zayamba bwino.
Igor, wazaka 56, Omsk
Dokotalayo adamuuza mankhwalawa kufupika. Zinthu zakhala bwino, sanazindikirebe zotsatila zilizonse.
