Cefepime ndimankhwala othana ndi bakiteriya omwe angathandize kuthana ndi matenda aliwonse omwe alowa m'thupi ndipo akhala nkhawa.
Dzinalo Losayenerana
Dzinalo Lachilatini ndi Cefepime.
Malinga ndi dzina lamalonda ndi mayiko ena osagwirizana, mankhwalawa amatchedwa cefepime.
Cefepime ndimankhwala othana ndi bakiteriya omwe angathandize kuthana ndi matenda aliwonse omwe alowa m'thupi ndipo akhala nkhawa.
ATX
Nambala ya ATX ndi J01DE01.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwala ndi ufa womwe umagwiritsidwa ntchito jekeseni wamkati ndi makonzedwe amkati. Ntchito yogwira - cefepime hydrochloride - ilipo pafupifupi 0,5 kapena 1 g pa botolo.
Zotsatira za pharmacological
Mankhwalawa ndi a m'badwo wachinayi wa cephalosporin antibacterial.
Zamoyo zotsatirazi zimakhala ndi chidwi ndi mankhwalawa:
- Staphylococcus epidermidis (epidermal staphylococcus);
- Streptococcus pneumoniae (pneumococcus);
- Klebsiella pneumoniae (wand wa Frindler);
- Staphylococcus aureus (Staphylococcus aureus);
- Enterobacter cloacae;
- Pseudomonas aeruginosa (Pseudomonas aeruginosa);
- Escherichia coli (E. coli);
- Citrobacter diversus;
- Providencia stuartii;
- Enterobacter agglomerans;
- Streptococcus pyogene;
- Haemophilus influenzae (hemophilus bacillus).
Mankhwala ndi ufa womwe umagwiritsidwa ntchito jekeseni wamkati ndi makonzedwe amkati.
Ma virus pang'ono otsatirawa amadziwika ndi kusazindikira kwa mankhwalawa:
- Clostridium Hardile;
- Xanthomonas maltophilia tizilombo ta;
- Enterococcus faecalis;
- Bacteroides fragilis;
- Legionella spp.
Pharmacokinetics
Mankhwala amapezeka mwachangu mkati mwa cell ya pathogenic ndipo samadziwika ndi beta-lactamase.
Kumangiriza kumapuloteni amwazi sikumayikidwa ndende ya plasma.
Zizindikiro zogwiritsidwa ntchito
Mankhwalawa amaperekedwa ngati wodwala akuwonetsa:
- matenda a kwamkodzo thirakiti, kuphatikizapo omwe ali ndi zovuta;
- bacterial mtundu wa meningitis (mu ubwana);
- chibayo
- matenda a pakhungu;
- neutropenic fever;
- zotupa zofewa;
- bronchitis ndi matenda ena a kupuma;
- gynecological pathologies, mwachitsanzo, vaginitis.
Contraindication
Mankhwalawa ali osavomerezeka kwa anthu omwe ali ndi hypersensitivity pakupanga mankhwala, komanso mankhwala ochokera ku gulu la penicillin ndi cephalosporins.
Ndi chisamaliro
Kwa odwala omwe ali pachiwopsezo cha kugwidwa ndi mankhwalawa, mankhwala opha maantibayotiki amayikidwa mosamala.
Momwe mungatengere nthawi yankholo
Njira zochizira ndi kumwa mankhwalawa zimatengera momwe wodwalayo alili ndi ntchito ya aimpso, motero mankhwalawa amayikidwa payekhapayekha. Pazachipatala, amafunsira dokotala ndipo amalandila malangizo.
Nthawi yovomerezeka ndi masiku 7 mpaka 10.
Woopsa milandu, dokotala atha kukulemberani mankhwala ena ake nthawi yayitali.
Pazachipatala, amafunsira dokotala ndipo amalandila malangizo.
Momwe mungaberekane mankhwala osokoneza bongo a cefepim
Mu njira ya makonzedwe a makonzedwe, mankhwalawa amasungunuka mu jekeseni wa madzi omwe paraben kapena phenylcarbinol amapezeka. Kugwiritsa ntchito 0,5% novocaine kapena 0,5-1% lidocaine sikuwululidwa.
Kuti mugwiritse ntchito intravenous, mankhwalawa amalowetsedwa mu isotonic sodium chloride solution.
Kumwa mankhwala a shuga
Mankhwalawa amagwiritsidwa ntchito molingana ndi malangizo ogwiritsa ntchito. Panthawi yamankhwala, ziyenera kukumbukiridwa kuti poyesa shuga mu mkodzo, zotsatira zake zimakhala zabodza.
Ndi matenda a shuga, mankhwalawa amagwiritsidwa ntchito molingana ndi malangizo ogwiritsira ntchito.
Zotsatira zoyipa
Kutsatira kwa maantibayotiki kungayambitse kupweteka kwapakati ndi kupweteka kwa malo a jakisoni.
Ndi kulowetsedwa kwa mtsempha wa magazi, phlebitis ndiyotheka - zotupa za makoma a venous.
Matumbo
Zotsatira zoyipa zamagetsi zimadziwika ndi mawonekedwe awa:
- kudzimbidwa
- kusintha kwa kukoma;
- yotupa njira ya m'matumbo, kuphatikizapo pseudomembranous colitis;
- nseru
- dysbiosis;
- kutsegula m'mimba
- kupweteka m'mimba.
Kugwiritsa ntchito mankhwalawa kumatha kutsegula m'mimba.
Hematopoietic ziwalo
Pali kuchepa kwa kuchuluka kwa hemoglobin m'magazi (magazi m'thupi).
Pakati mantha dongosolo
Nthawi zambiri, mutu umayamba. Khunyu ndi chizungulire sizachilendo.
Kuchokera ku kupuma
Zotsatira zoyipa zimawonekera mu mawonekedwe a chifuwa.
Kuchokera ku genitourinary system
Odwala ambiri omwe akumana ndi zozizwitsa amakhala ndi zizindikiro zotsatirazi:
- candidiasis osatsata;
- kuyabwa koyambirira;
- mwa akazi, kutukusira kwa mucosa ya ukazi;
- matenda aimpso.
Mukatenga, kulephera kwa impso kumatha kuchitika.
Kuchokera pamtima
Odwala adawona zofananira:
- kupuma movutikira
- zokonda mtima.
Matupi omaliza
Zizindikiro zotsatirazi zikuwonekera:
- zotupa pakhungu;
- anaphylactic zimachitika;
- kutentha thupi.
Mukamwa mankhwalawa, khungu limayamba kuoneka.
Malangizo apadera
Odwala omwe akupitilira peritoneal dialysis amathandizira pakapita pakati pa mankhwala opha maantibayotiki. Potere, mankhwalawa amatumizidwa maola 48 aliwonse.
Zokhudza mphamvu pakuwongolera njira
Ndikulimbikitsidwa kukana kugwiritsa ntchito mayendedwe mpaka thupi litayankhidwa pakumwa mankhwala. Ngati pali zovuta zoyipa zomwe zimakhudza chidwi cha anthu (mutu, chizungulire), muyenera kukana kuyendetsa galimoto.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Mankhwalawa amapita mkaka wa m'mawere, panthawi yamankhwala, amafunika kusamutsa mwana kuti asakanikirane. Kupanda kutero, muyenera kupeza chida choyenera kwambiri.
Kafukufuku wachitika kuti aphunzire momwe mankhwalawo amathandizira thupi la mayi ndi mwana wosabadwa sichinachitike. Chifukwa cha chifukwa ichi, palibe chidziwitso chokhudza kumwa mankhwalawa. Ngati pakufunika kuchita chithandizo chamankhwala, ndiye kuti chimachitika pokhapokha ndi chilolezo cha dokotala komanso moyang'aniridwa naye.
Ndikulimbikitsidwa kukana kugwiritsa ntchito mayendedwe mpaka thupi litayankhidwa pakumwa mankhwala.
Kupangira Cefepime kwa Ana
Antibacterial wothandizila sagwiritsidwa ntchito kuchitira ana osakwana miyezi iwiri. Nthawi zina, maantibayotiki amagwiritsidwa ntchito ndi chilolezo cha katswiri.
Gwiritsani ntchito mu ukalamba
Kwa odwala okalamba, kuchuluka kwa mankhwalawa kuyenera kusinthidwa, chifukwa chake, kufunsa kwa dokotala ndikofunikira.
The ntchito aimpso kuwonongeka
Ngati kulephera kwa impso, mlingo umayikidwa kuganizira creatinine chilolezo. Ngati chizindikirocho chili chochepera 30 ml pamphindi, ndiye kuti muyenera kusankha kuchuluka kwa mankhwalawo.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Kusintha kwa mankhwalawa sikofunikira, komabe, wodwalayo ayenera kuyang'aniridwa kuti ayang'anire kuchuluka kwa mankhwalawa m'magazi.
Bongo
Kuchulukitsa kuchuluka kovomerezeka kwa mankhwalawa kumabweretsa mawonetsedwe ofanana:
- kuyerekezera;
- tsinde;
- chisokonezo cha chikumbumtima;
- kupindika minofu.
Kuchulukitsa kuchuluka kovomerezeka kwa mankhwalawa kumabweretsa kuyerekezera zinthu.
Kuphatikiza apo, zizindikiro za zoyipa zimatha kukula. Wodwala ayenera kupita kuchipatala.
Kuchita ndi mankhwala ena
Sitikulimbikitsidwa kuphatikiza kumwa maantibayotiki ndi mankhwala otsatirawa:
- aminoglycosides - chiwopsezo cha kuwonongeka kwa ma vestibular ndi makina owerengera amawonjezeka; kuchuluka kwa impso;
- Metronidazole yankho;
- mankhwala okhala ndi antimicrobial.
Kuyenderana ndi mowa
Mankhwalawa saphatikizidwa ndi zinthu zomwe zimakhala ndi ethyl mowa. Kunyalanyaza lamuloli kumapangitsa kuti chiwopsezo ndi ziwalo zina ziwonjezeke.
Mankhwalawa saphatikizidwa ndi zinthu zomwe zimakhala ndi ethyl mowa.
Analogi
Zofananazo zimakhala ndi njira:
- Ceftriaxone ndi mankhwala a 3 m'badwo wa cephalosporin. Mankhwala olimbana ndi mankhwalawa amagwira ntchito pothana ndi gramu-gram ndi microflora ya gram.
- Maxipim ndi antibacterial wothandizirana ndi beta-lactamase.
- Movizar ndi mankhwala a mibadwo 4 ogwiritsira ntchito antchito.
- Cephalexin ndi mankhwala omwe amamasulidwa mu mawonekedwe a granules pakuyimitsidwa ndi mapiritsi. Mankhwalawa amathandizira kuti ziwonongeko za mabacteria azikhala, zomwe zimapangitsa kuti azifa. Zosagwirizana ndi beta-lactamases.
- Maksicef ndi antibacterial wothandizira omwe ali ndi zochita zambiri.
Kupita kwina mankhwala
Amamasulidwa pa chiwonetsero cha Chinsinsi.
Kodi ndingagule popanda kulandira mankhwala?
Kuti mugule mankhwala, fomu yofunsira ndiyofunikira.
Kuti mugule mankhwala, fomu yofunsira ndiyofunikira.
Mtengo wa cefepim
Kugulitsa mankhwalawa kumachitika ndi mtengo wa ma ruble 98-226.
Zosungidwa zamankhwala
Mankhwala oteteza mankhwalawa ayenera kutetezedwa kuti asayerekezedwe ndi dzuwa kapena kutentha kwambiri. Yankho lokonzekera limaloledwa kuti lisungidwe osaposa tsiku kutentha kwa chipinda komanso osapitilira sabata limodzi mufiriji.
Tsiku lotha ntchito
Mankhwalawa ndi oyenera kwa zaka zitatu.
Wopanga
Kutulutsidwa kwa ndalamaku kumachitidwa ndi Indian kampeni ya Brown Laboratories Limited.
Umboni wa madokotala ndi odwala za Cefepime
Maria Sergeevna, dokotala wa matenda opatsirana
Kugwiritsa ntchito nkhumba ya cefepime kuyenera kuchitika ndi chilolezo cha adokotala, monga mankhwalawa ali ndi mphamvu. Ubwino wa mankhwalawa ndi kulephera kukana kwa mankhwalawo ku mabakiteriya, kotero, maantibayotiki amathandiza pakakhala zovuta zina.
Inna, wazaka 38, Tyumen
Kugwiritsa ntchito nthawi ya mphodza kunali kofunikira pneumonia itachitika mwa mwana, yemwe panthawiyo anali ndi miyezi isanu. M'mbuyomu, maantibayotiki ena amagwiritsidwa ntchito, koma sizinathandize, chifukwa chake adapereka ma jakisoni ndi mankhwalawa. Maphunzirowa adatha sabata. Pambuyo pa chithandizo, adapita kuchipatala kuti akawonetsetse. Zotsatira zake zinawonetsa kuti mwanayo ndi wathanzi.
Anatoly, wazaka 39, Syzran
Pakupanga kwa pyelonephritis, jekeseni wa cefepim ndi mankhwala. Mankhwalawa adagwiritsidwa ntchito kwa masiku pafupifupi 5-7, koma kusintha kwake kumachitika bwino pambuyo pobayidwa woyamba jakisoni. Zotsatira zake, matendawa adasowa, palibe zovuta. Pambuyo pa chithandizo, panali matumbo ndi matumbo, koma mothandizidwa ndi Bifidumbacterin adatha kusintha ntchito ya thupi.
