Galvus Met ndi mankhwala omwe amagwiritsidwa ntchito pofuna kusintha matupi athu ndi matenda ashuga. Imakhala ndi contraindication, chifukwa chake iyenera kugwiritsidwa ntchito motsogozedwa ndi dokotala.
Dzinalo Losayenerana
Vildagliptin + metformin.
Galvus Met ndi mankhwala omwe amagwiritsidwa ntchito pofuna kusintha matupi athu ndi matenda ashuga.
ATX
A10BD08.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwalawa amapezeka mu mawonekedwe a mapiritsi okhala ndi mawonekedwe ozunguliridwa, okutidwa ndi filimu ya enteric ya mtundu wa pinki. Pa dzanja limodzi pali cholembedwa "NVR", mbali inayo - "LLO". Piritsi lililonse lili ndi:
- vildagliptin (50 mg);
- metformin hydrochloride (100, 1000 kapena 850 mg);
- hyprolose;
- magnesium wakuba;
- titanium oxide wopanda madzi;
- macrogol;
- oxide wachitsulo ndi wofiyira.
Mapiritsi amaikidwa m'matumba a contour a zidutswa 10, makatoni okhala ndi 1 matuza ndi malangizo.
Zotsatira za pharmacological
Zinthu zomwe zimagwira ndi izi:
- Ziletsa ntchito ya dipeptidyl peptidase-4, yomwe imawonjezera kuchuluka kwa michere ya glucagon m'magazi. Izi zimapangitsa kuti ma cell a pancreatic azindikire glucose. Izi zimawonjezera kupanga kwa insulin yofunikira pakuchepa kwa shuga. Kukula kwa kusintha kwa magwiridwe antchito a maselo a ziwanda kumatengera mtundu wazowonongeka.
- Kuchulukitsa zomwe zili ndi enzyme ya glucagon, yomwe imakupatsani mwayi wopanga glucagon. Kutsika kwa zinthu za peptide mukatha kudya kumapangitsa kuchepa kwa insulin. Kuwonjezeka kwa kuchuluka kwa insulin / glucagon motsutsana ndi maziko a shuga ochepetsedwa kumalepheretsa kupanga glycogen owonjezera m'chiwindi.
- Kuchepetsa zomwe zimakhala ndi ma lipoprotein otsika kwambiri m'magazi, zomwe zimafotokozedwa ndi kukondoweza kwa maselo am'mimba mwa kapamba.
- Kuchulukitsa kukana kwa glucose kwa odwala omwe ali ndi matenda a shuga a 2. Chepetsani kuchuluka kwa shuga m'magazi musanadye kapena pambuyo pake.
- Osamayambitsa kuchepa kwakukulu kwa kuchuluka kwa shuga m'magazi ngakhale odwala matenda ashuga, kapena anthu athanzi. Kuchiza ndi mankhwalawa sikuthandizira hyperinsulinemia. Kapangidwe ka insulin sikunasinthe, pomwe kuchuluka kwa mahomoni m'magazi kumatha kusiyanasiyana malinga ndi chakudya.
- Kubwezeretsa kagayidwe kazakudya zama protein, mafuta ochepetsa cholesterol ndi triglycerides m'thupi.
Pharmacokinetics
60% ya mankhwalawa amatengedwa m'magazi. The achire plasma ndende amadziwika pambuyo 2-2,5 maola. Kudya kungachedwetse kuyamwa kwa zinthu zofunikira. Ndi jakisoni imodzi ya mankhwalawa, ambiri amachotsedwa mu mkodzo. Mankhwala samasinthika m'chiwindi ndipo samalowa mu bile. Hafu ya moyo wophatikizika wazinthu zimatenga maola 17.
Zizindikiro zogwiritsidwa ntchito
Zisonyezo zakugwiritsa ntchito mankhwala a shuga ndi:
- kusakwanira kwa magwiritsidwe antchito ogwiritsa ntchito omwe amapanga Galvus Met;
- kuphatikiza mankhwala ndi metformin ndi vildagliptin, ogwiritsidwa ntchito ngati monopreparations;
- kulandira kuphatikiza kwa insulin popanda kuwongolera glycemic;
- koyamba chithandizo cha odwala omwe ali ndi matenda a shuga a 2 omwe ali ndi kusakwanira kwa chakudya komanso masewera olimbitsa thupi.
Contraindication
Mankhwala sakhazikitsidwa:
- kusalolera kwa munthu payekha popanga zosakaniza zothandizira;
- kuchepa kwa thupi;
- machitidwe a hypoxic;
- pachimake komanso matenda a mtima kulephera;
- myocardial infarction;
- kuphwanya ntchito za kupuma;
- metabolic acidosis;
- kukonzekera kuchitira opaleshoni ndikuwunika kwa x-ray (mankhwalawa satengedwa maola 48 isanachitike njirayi);
- mtundu 1 shuga;
- uchidakwa wambiri, kuledzera kwa pachimake;
- Kutsatira zakudya zama calorie ochepa.
Ndi chisamaliro
Contraindative zokhudzana ndi izi:
- m'badwo wachikale ndi wovuta;
- kulimbitsa thupi, kuwonjezera ngozi ya lactic acidosis.
Momwe mungatenge Galvus Met
Ndi matenda ashuga
Mlingo wakhazikitsidwa kutengera kuuma kwa matenda ndi kulolerana kwa chithandizo. Musapitirire muyeso wovomerezeka wa vildagliptin (100 mg). Kuti muchepetse zovuta za mapiritsi, timalimbikitsidwa kumwa pakudya. Mu shuga yayikulu, mankhwalawa amatengedwa pamimba yopanda kanthu. Kuphatikiza mankhwala kumayamba ndi kuyambitsa 50 + 500 mg ya mankhwala 2 kawiri pa tsiku. Pakutha kugwira ntchito, mlingo wa metformin ukuwonjezeka mpaka 850 mg.
Zotsatira zoyipa za Galvus Met
Poyerekeza ndi chithandizo cha mankhwala ndi Galvus Met, zotsatirazi zingachitike:
- kusokonezeka kwa mitsempha (kupweteka mutu, chizungulire, kunjenjemera,
- matenda a metabolic (hypoglycemia);
- zotupa pakhungu (kuyabwa, zotupa, zotupa thukuta);
- matenda ammimba (mseru, kusanza, kumva kupweteka m'mimba, chosakhazikika);
- Zizindikiro zakuwonongeka kwa minofu ndi mafupa olowa);
- zotsatira zina zoyipa (kutupa kwa m'munsi, kukhumudwa kwa anaphylactic, kuyamwa kwa vitamini B12).
Zokhudza mphamvu pakuwongolera njira
Mphamvu ya mankhwalawa pozungulira komanso kuchuluka kwa zomwe ma psychomotor amachita sizinaphunzire. Mankhwalawa amatha kubweretsa chizungulire, chifukwa chake, mankhwalawa amakana kuyendetsa galimoto komanso njira zovuta.
Malangizo apadera
Gwiritsani ntchito mu ukalamba
Mankhwalawa okalamba ndi a senile, kusintha kwa mankhwala kumafunika. Munthawi ya chithandizo, kuyezetsa magazi pafupipafupi kumakhala kofunikira.
Kupatsa ana
Chitetezo cha zinthu zomwe zimagwira thupi la mwana sichinatsimikizidwe, chifukwa chake kugwiritsa ntchito Galvus Met ndi odwala omwe ali ndi zaka zochepa sikuletsedwa.
Mankhwalawa okalamba ndi a senile, kusintha kwa mankhwala kumafunika.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Mankhwalawa amathandizira kuthana ndi zotchinga ndikuyika mkaka. Chitetezo cha zinthu zogwira ntchito kwa mwana wosabadwayo ndi mwana yemwe ali mkaka wa m'mawere sichinaphunzire. Chifukwa chake, kukhala ndi pakati komanso mkaka wa m`mawere kumaphatikizidwa pamndandanda wazotsutsana.
The ntchito aimpso kuwonongeka
Mu matenda owopsa a impso, kuchepetsa kuchuluka kwa Galvus Met kungafunike.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Ngati chiwindi ntchito, mankhwala osokoneza bongo amafuna kuwunika pafupipafupi magawo a biophemical a chiwalo.
Overdose wa Galvus Met
Kuchulukitsa Mlingo wotchulidwa ndi dokotala kumawonjezera mavuto. Mankhwalawa amathandizira mwachilengedwe. Kutsegula m'mimba sikugwira ntchito kwenikweni, motero sikugwiritsidwa ntchito.
Mu matenda owopsa a impso, kuchepetsa kuchuluka kwa Galvus Met kungafunike.
Kuchita ndi mankhwala ena
Liazide diuretics imachulukitsa kuchuluka kwa excretion kwa Galvus Met. Nifedipine imawonjezera mayamwa. Glibenclamide sichikhudza kuchuluka kwa mayamwidwe a metformin ndi vildagliptin. Cardiac glycosides amatha kumangiriza ku metformin, ndikuchepetsa kuchepa kwa metabolic. Kugwirizana kwamankhwala osokoneza bongo omwe ali ndi antipsychotic ali osavomerezeka.
Kuyenderana ndi mowa
Ethanol imawonjezera chiopsezo cha lactic acidosis, chifukwa chake amakana kumwa mowa pakumwa.
Analogi
Otsatirawa ali ndi zomwezi:
- Amaryl M;
- Galvus;
- Glibomet;
- Glformin.
Kupita kwina mankhwala
Kodi ndingagule popanda kulandira mankhwala?
Pamafunika mankhwala kuti mugule mankhwalawo.
Mtengo wa Galvus Met
Mtengo wapakati wa mapiritsi 30 ndi ma ruble 1,500.
Zosungidwa zamankhwala
Mankhwalawa amasungidwa m'malo amdima, osalola kuti kutentha kutentha + 30 ° C.
Tsiku lotha ntchito
Miyezi 18 kuchokera tsiku lotuluka.
Wopanga
Mankhwalawa amapangidwa ndi kampani yaku Swiss ya Novartis Pharma.
Ndemanga ya Galvus Met
Victoria, wazaka 45, ku Moscow: "Ndakhala ndikudwala matenda a shuga kwa nthawi yayitali, motero dotolo adapereka mankhwala omwe ali ndi metformin ndi vildagliptin nthawi yomweyo. Mankhwalawa amathandizirana, motero mankhwalawa amachepetsa shuga wamagazi ndikuthandizira kukhalabe mfundo zabwino. "
Arthur, wazaka 34, ku Moscow: "Ndikudwala matenda ashuga a mtundu wa 2. M'mbuyomu ndidalandira chithandizo cha mankhwala a Metformin. Shuga itayamba kuchuluka, Diabeteson adaliphatikizidwanso m'mankhwala othandizira Komabe. zomwe zimapangitsa kuti zitheke popanda insulini. "
