Kuchita bwino kwa mankhwala opha maantibayotiki kumadalira mphamvu ya mabakiteriya omwe amakana mankhwala. Pofuna kuchiza matenda, madokotala amakakamizika kugwiritsa ntchito mphamvu zophatikiza zingapo nthawi imodzi.
Kugwiritsa ntchito pamodzi mankhwala a 2 kapena 3 omwe ali ndi mayendedwe osiyanasiyana amalepheretsa kukana kwa tizilombo toyambitsa matenda komanso kubwezeretsa chidwi chamankhwala. Chifukwa chake, pakuchotsa zovuta za Helicobacter pylori, zomwe zimayambitsa kukula kwa zilonda zam'mimba ndi mitundu ina ya gastritis, kuphatikiza kwa Amoxicillin ndi Clarithromycin kumagwiritsidwa ntchito.
Khalidwe la Amoxicillin
Mankhwala othana ndi penicillin amadziwika ndi mankhwala ambiri, otsika komanso osafunikira m'mimba (mpaka 95%). Makina a antibacterial zochita za chinthucho ndi kuti atseke kapangidwe ka mapuloteni omwe amapanga khoma la cell la tizilombo tomwe timayambitsa kukula, ndipo timayambitsa kufa kwawo.
Pakutha kwa Helicobacter pylori tizilombo tomwe timayambitsa zilonda zam'mimba komanso mitundu ina ya gastritis, kuphatikiza kwa Amoxicillin ndi Clarithromycin kumagwiritsidwa ntchito.
Kodi Clarithromycin ali bwanji
Anti-synthetic antiotic kuchokera ku gulu la macrolide limakhala ndi bacteriostatic, ndipo mwakuya kwambiri kumawonetsa katundu wa bactericidal. Mankhwala achulukitsa ntchito motsutsana ndi Helicobacter pylori poyerekeza ndi zinthu zomwe zili mndandanda wawo. Clarithromycin amatha kupanga ndende mu chapamimba pamimba kwambiri kuposa seramu yamagazi, yomwe imawafotokozera ngati woyamba kusankha mankhwala a gastroenterology.
Kuphatikiza
Bacterium Helicobacter pylori, yomwe imayambitsa mitundu ya HP yokhudzana ndi matenda am'mimba, imayamba kukhala ndi antibayotiki. Kuthekera kwakuti ma tizilombo ting'onoting'ono timayamba kuthana ndi zinthu zingapo nthawi imodzi kumachepera kangapo.
Clarithromycin osakanikirana ndi Amoxicillin amatha kupondereza kukula ndi kubereka kwa mabakiteriya mwakukulitsa mawonekedwe awowonekera komanso njira zosiyanasiyana zokopera pathogen. Kapangidwe ka kakonzedwe kakatatu kotsatirira kamaphatikizira proton pump inhibitors - Omeprazole kapena analogues. Amoxicillin akhoza m'malo mwa metronidazole.
Amoxicillin ndimankhwala othana ndi penicillin, omwe amadziwika ndi mankhwala osiyanasiyana.
Zizindikiro zogwiritsidwa ntchito munthawi yomweyo
Kuphatikiza kwa mankhwalawa kumagwiritsidwa ntchito pochiza matenda amtundu osiyanasiyana oyambitsidwa ndi tizilombo tating'onoting'ono:
- streptococcus;
- nsomba;
- staphylococcus;
- chlamydia
- E. coli.
Maantibayotiki onsewa amawononga tizilombo tating'onoting'ono tomwe timapangidwa, komanso tikamalimbikitsana kulimbikitsana.
Kuphatikiza kumayikidwa kwa ma pathologies awa:
- gastroduodenal matenda a bakiteriya chikhalidwe: zilonda zam'mimba, gastritis, khansa ya m'mimba;
- matenda kupuma thirakiti;
- zotupa pakhungu;
- chifuwa chachikulu.
Kuphatikiza mankhwala kumawonetsedwa makamaka pamankhwala omwe sangathe kuthandizidwa ndimankhwala amodzi.
Clarithromycin ndi mankhwala ochititsa chidwi a macrolide omwe ali ndi bacteriostatic.
Kuphatikiza kwa Clarithromycin-Amoxicillin-Omeprazole ndiye njira yabwino kwambiri yothandizira kuti zithetsedwe kwa Helicobacter pylori, ndikuthandizira kuchira kwa 85-95% ya milandu. Mankhwala ovuta a Pilobact AM omwe amachokera pazinthu zitatu adapangidwa mwachindunji pochiza matenda omwe amadalira Helicobacter.
Contraindication
Mankhwala awiri sangathe kugwiritsidwa ntchito pazinthu zotere:
- matupi awo sagwirizana ndi penicillin;
- tsankho:
- kulephera kwambiri kwa impso kapena chiwindi;
Osatipatsa kuphatikiza mu 1 trimester ya mimba. Mosamala, mankhwalawa amagwiritsidwa ntchito pa diathesis, mphumu, matenda a impso, leukemia, mu 2-3 trimester ya mimba komanso nthawi ya mkaka wa m`mawere.
Momwe mungatenge Amoxicillin ndi Clarithromycin
Ndi mankhwala ophatikiza, mitundu yonse ya mankhwalawa imagwiritsidwa ntchito molingana ndi malangizo. Mapiritsi kapena makapisozi amatengedwa ndi zakudya. Mu matenda a chiwindi ndi impso, Mlingo umachepetsedwa.
Kuphatikiza kwa Clarithromycin-Amoxicillin-Omeprazole ndiye njira yabwino kwambiri yothandizira kuti zithetsedwe kwa Helicobacter pylori, ndikuthandizira kuchira kwa 85-95% ya milandu.
Gastritis
Ndi Helicobacter pylori gastritis, chithandizo chimasankhidwa payekha. Mankhwala onse omwe amathandizira kuchepetsa acidity yam'mimba (prostaglandins) ndi mankhwala omwe amagwiritsidwa ntchito mosiyanasiyana amasiyana.
Mulingo wothandizirana ndi mankhwalawa umaphatikizapo kugwiritsa ntchito mankhwala atatu pazitetezo zotere:
- Clarithromycin - 500 mg;
- Amoxicillin - 1000 mg;
- Omeprozole - 20 mg.
Mankhwala onse amatengedwa kawiri patsiku; Njira yovomerezeka imatha masiku 7.
Kuchokera ku chifuwa chachikulu
Kuphatikiza mankhwala kumasankhidwa payekha.
Chiwembu chogwiritsidwa ntchito nthawi zambiri:
- Amoxicillin - kuchokera 500 mpaka 1000 mg kawiri pa tsiku;
- Clarithromycin - kuchokera 250 mg mpaka 500 mg 2 kawiri pa tsiku.
Amoxicillin osakanikirana ndi clarithromycin amaikidwa m'gulu lachiwiri la anti-TB. Bacteria kukana kwa awiriwa ndizochepa kwambiri kuposa mankhwala ochokera ku gulu loyamba.
Kwa matenda apakhungu
Systemic mankhwala othandizira amachitika matenda a pakhungu lofatsa komanso loletsa:
- erysipelas;
- furunculosis;
- folliculitis;
- impetigo;
- mabala opatsirana.
Woopsa, mankhwala opha maantibayotiki ndiwonjezeranso njira zopangira opaleshoni.
Zotsatira zoyipa za amoxicillin ndi clarithromycin
Zotsatira zoyipazi zimapezeka:
- nseru
- kusanza
- Chizungulire
- zotupa pakhungu;
- dysbiosis.
Chomwe chimadziwika kwambiri ndi kukula kwa hypovitaminosis, kufooka chitetezo chathupi. Mphamvu yolerera pakamwa imatha kuchepetsedwa.
Malingaliro a madotolo
Gastroenterologists ndi madokotala azinthu zina zomwe amachita poonetsetsa kuti njira zamankhwala othandizira othandizira zimagwirira ntchito. Malinga ndi akatswiri, lamulo lalikulu la chithandizochi likutsatira zomwe mankhwala akupereka komanso mankhwala. Simungathe kupereka mitundu yophatikizira ya mankhwala motsutsana.
Ndemanga za Odwala Amoxicillin ndi Clarithromycin
Sergey, wazaka 48, Voronezh
Zilonda zanga zimayamba chifukwa cha mabakiteriya. Adalemba njira yothandizira, zinali zowopsa pang'ono - pali mankhwala ambiri, koma ndidamwa kwathunthu. Patatha mwezi umodzi ndidadutsa mayeso - zonse zili bwino.
Irina, wazaka 25, Moscow
Dokotala adakhazikitsa maantibayotiki awiri ochizira Helicobacter pylori gastritis. Zinthu zayamba bwino. Palibe zovuta zomwe zikuwoneka kale.
