Telsartan 80 ndi mankhwala omwe ali ndi angiotensin antagonists. Amagwiritsidwa ntchito pochiza matenda oopsa ndi zina.
Dzinalo Losayenerana
Telmisartan.
ATX
Nambala ya ATX ndi C09C A07.
Kutulutsa mafomu ndi kapangidwe kake
Amapezeka piritsi. Yogwira pophika mankhwala ndi telmisartan. Piritsi limodzi lili ndi 80 mg yogwira ntchito, ndi yoyera ndi utoto. Mapiritsiwo sanapangidwe, aliyense wa iwo ali ndi zolemba nambala 80 mbali imodzi.
Monga zinthu zothandizira, sodium hydroxide, madzi, povidone, meglumine, magnesium stearate ndi machitidwe a mannitol.
Telsartan 80 ndi mankhwala omwe amagwiritsidwa ntchito pochiza matenda oopsa komanso zina.
Zotsatira za pharmacological
Mphamvu ya antihypertensive yogwira ntchito imatsimikizika ndikuletsa kutsekeka kwa maselo a ziwiya zokhudzana ndi angiotensin 2. molekyulu ya telmisartan ili ndi mawonekedwe ofanana amtunduwu, chifukwa chake imafikira ku receptors m'malo mwa mahomoni, kutseka kwake. Kamvekedwe ka mtima sikachuluka, komwe kumayimitsa kukwera kwa magazi.
Yogwira pophika mankhwala imamangirira ma receptors kwa nthawi yayitali. Makhalidwe, ma receptor a AT1 subtype ndi oletsedwa. Ma subtypes ena a angiotensin receptors amakhalabe omasuka. Udindo wawo weniweni mthupi sunaphunziridwe mokwanira, chifukwa chake sayenera kukhala wololera kuyendetsa magazi.
Mothandizidwa ndi mankhwalawa, kupanga aldosterone yaulere imalepheretsanso. Nthawi yomweyo, kuchuluka kwa renin kumakhalabe chimodzimodzi. Njira zosiyanasiyana za ma cell zomwe zimayendetsa ma ion sizikhudzidwa.
Telsartan si angiotensin osintha enzyme inhibitor. Izi zimapangitsa kuti zikhale zovuta kuti zizindikire zina zosafunikira, chifukwa michere iyi imathandizanso kuti bradykinin iwonongeke.
Pharmacokinetics
Mothandizidwa ndi pakamwa mankhwala, kachigawo kameneka kamadutsa msanga kudzera m'matumbo aang'ono. Imatsala pang'ono kunyamula ma peptides. Ambiri amayendetsedwa molumikizana ndi albin.
Zokwanira bioavailability wa mankhwala pafupifupi 50%. Zitha kuchepetsedwa ndi mankhwala okhala ndi zakudya.
Njira yayikulu yogwiritsira ntchito kusintha kwa kagayidwe kachakudya mu thupi ndi cholumikizira ku glucuronide. Zotsatira zomwe zilibe ntchito za pharmacological.
Zambiri zomwe zimagwira zimachotsedwapo kale. Hafu ya moyo ndi maola 5-10. Gawo lomwe limagwira ntchito bwino limachoka m'thupi mu maola 24.
Zizindikiro zogwiritsidwa ntchito
Chida chimagwiritsidwa ntchito:
- matenda oopsa;
- kupewa kufa kwa matenda a CVD mwa anthu azaka 55 omwe ali pachiwopsezo cha chitukuko chawo chifukwa cha kusokonezeka kwa mtima;
- kupewa zovuta za omwe ali ndi matenda osokoneza bongo omwe amadalira odwala omwe amapezeka ndi kuwonongeka kwa ziwalo zamkati zomwe zimayenderana ndi matenda oyamba.
Contraindication
Contraindging poika mankhwalawa ndi:
- Hypersensitivity kwa chophatikizira chachikulu kapena zinthu zina zomwe zimapanga;
- bile duct kutsekeka;
- kusakwanira kwa kwa chiwindi ntchito pa kuwonongeka;
- cholowa chokhala ndi mkaka wamphesa;
- zaka mpaka 18;
- mimba ndi mkaka wa m`mawere.
Ndi chisamaliro
Mosamala, mankhwalawa amaperekedwa kwa odwala omwe ali ndi vuto lochepa kwambiri kwa chiwindi.
Momwe mungatenge Telsartan 80
Mapiritsi amatengedwa tsiku lililonse. Mutha kumwa mosasamala nthawi yakudya, ndi madzi ofunika.
Mlingo woyambirira ndi 40 mg. Ngati kuchuluka kwa mankhwalawa sikulola kuwongolera kwathunthu kwa kuthamanga kwa magazi, mlingo umakulitsidwa.
Mlingo wapamwamba tsiku lililonse ndi 80 mg. Kuwonjezeka kwina sikopanda tanthauzo chifukwa sikumabweretsa chiwopsezo cha mankhwala.
Tiyenera kudziwa kuti mphamvu ya mankhwalawa sikuwoneka nthawi yomweyo. Kutheka kokwanira kumatheka pambuyo pa miyezi 1-2 yogwiritsa ntchito mosalekeza.
Telsartan nthawi zina amaphatikizidwa ndi thiazide diuretics. Kuphatikiza uku kumatha kuchepetsa kupsinjika.
Woopsa matenda oopsa, 160 mg wa telmisartan akhoza kutumikiridwa limodzi ndi 12.5-25 mg wa hydrochlorothiazide.
Ndi matenda ashuga
Mtundu wachiwiri wa matenda ashuga, Telsartan angatengedwe kuteteza kupewetsa mtima kwa impso, mtima, ndi retina. Mankhwala ndi mankhwala 40% kapena 80 mg, malingana ndi kuopsa kwa mawonekedwe a matenda oopsa.
Mankhwalawa amatengedwa nthawi yayitali. Kafukufuku wachipatala akuwonetsa kuti magazi a systolic ndi diastolic amatsika ndi 15 ndi 11 mm Hg pamene amatengedwa kuyambira masabata 8 mpaka 12. Art. motero.
Odwala omwe ali ndi matenda ashuga komanso matenda oopsa amatha kuphatikizidwa ndi amlodipine. Kuphatikizika kumeneku kumakupatsani mwayi woti mulimbikitse kuthamanga kwa magazi mkati mwazotheka.
Musanagwiritse ntchito mankhwalawa, muyenera kufunsa dokotala. Mlingo ndi nthawi yayitali ya chithandizo iyenera kusankhidwa payekha.
Ndikofunikira kukaonana ndi dokotala. Mlingo ndi nthawi yayitali ya chithandizo iyenera kusankhidwa payekha.
Zotsatira zoyipa za Telsartan 80
Kafukufuku wasonyeza kuti pafupipafupi zovuta zomwe zimachitika mutatenga Telsartan zimakhala zofanana ndi pafupipafupi momwe zimachitikira odwala omwe akulandira placebo. Sanatchulanso zaka komanso mtundu wa anthu.
Matumbo
Kuchokera pamiyambo yogaya chakudya titha kuona:
- kupweteka kwam'mimba
- kamwa yowuma
- kutsegula m'mimba
- nseru
- kusanza
- dyspeptic matenda;
- chisangalalo.
Hematopoietic ziwalo
Kuchokera ku ziwalo za hemopoietic zitha kuwoneka:
- kuchepa magazi
- thrombocytopenia;
- eosinophilia;
- kutsika kwa hemoglobin.
Pakati mantha dongosolo
Mphamvu yamkati imatha kuyankha mankhwalawa chifukwa cha:
- mavuto okhumudwitsa;
- kusowa tulo
- nkhawa;
- kugona
- kuwonongeka kwamawonekedwe;
- chizungulire.
Kuchokera kwamikodzo
Mankhwala angayambitse:
- aimpso kuwonongeka;
- pachimake aimpso kulephera.
Kuchokera ku kupuma
Telsartan angayambitse:
- kupuma movutikira
- kutsokomola
- matenda ochepa kupuma thirakiti.
Pa khungu
Zitha kuchitika:
- thukuta kwambiri;
- kuyabwa
- zotupa
- erythema;
- kutupa
- dermatitis;
- urticaria;
- chikanga
Kuchokera ku genitourinary system
Ntchito zogonana sizivutika mukamamwa Telsartan.
Kuchokera pamtima
- ochepa hypotension;
- orthostatic hypotension;
- tachy, bradycardia.
Kuchokera musculoskeletal system ndi minofu yolumikizana
Mphamvu ya minofu ndi mafupa amatha kuyankha mankhwalawa ngati:
- kupweteka kwa minofu ndi molumikizana;
- kupweteka kwa tendon;
- kulanda
- lumbalgia.
Pa mbali ya chiwindi ndi biliary thirakiti
Mothandizidwa ndi telmisartan, kuchuluka kwa ntchito ya ma enzymes a chiwindi kumasintha.
Matupi omaliza
Anaphylactic zimachitika mankhwala akhoza kuchitika.
Zokhudza mphamvu pakuwongolera njira
Kafukufuku wokhudzana ndi mphamvu ya mankhwalawa pakuwongolera machitidwe sanachitike. Ndikulimbikitsidwa kuti muchepetse nthawi yomwe mumagwiritsa ntchito poyendetsa zizindikiro za mbali yam'mimba.
Pochita mankhwala ndi Telsartan, tikulimbikitsidwa kuchepetsa nthawi yogwiritsidwa ntchito pa gudumu.
Malangizo apadera
Hypotension imatha limodzi ndi muyezo woyamba wa mankhwalawa odwala omwe ali ndi magazi osakwanira kapena kuchuluka kwa plasma sodium.
Pachimake ochepa hypotension amatha kuchitika ngati wodwala aimpso mtima stenosis kapena mtima woipa kulephera.
Telmisartan siothandiza pochiza odwala omwe ali ndi hyperaldosteronism yoyamba.
Mosamala, mankhwalawa amaperekedwa kwa anthu omwe ali ndi aortic kapena mitral valve stenosis.
Kugwiritsa ntchito mankhwalawa kumatha kuyambitsa kuchuluka kwa potaziyamu m'magazi. Magulu ena odwala angafunike kuwunikira kwakanthawi ma electrolyte a plasma.
Pali chiopsezo cha hypoglycemia mwa anthu omwe amalandira insulin kapena mankhwala ena a antiidiabetes. M'pofunika kuganizira izi posankha mtundu wa mankhwalawa. Ndikofunikira kuyang'anitsitsa kuchuluka kwa shuga m'magazi.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Chithandizo cha Telmisartan sichingaperekedwe panthawi yapakati. Ngati pakufunika kupitiliza mankhwala a antihypertensive, ndikofunikira kukaonana ndi dokotala. Adzasankha mankhwala oyenera kuti alowe m'malo.
Ngati ndi kotheka, kugwiritsa ntchito mankhwala ochizira azimayi pa mkaka wa m'mawere kumalimbikitsidwa kusamutsa mwana kuti akwanitse kudya. Kusamala kumeneku kumachitika chifukwa chosowa chidziwitso cha telmisartan, yomwe imatha kupezeka mkaka, mthupi la makanda.
Kulemba Telsartan kwa ana 80
Mankhwalawa sagwiritsidwa ntchito pochiza odwala osakwana zaka 18.
Gwiritsani ntchito mu ukalamba
Kugwiritsidwa ntchito kwa Telsartan muukalamba kulibe mawonekedwe pokhapokha pakuchita zotsutsana mwa odwala.
Kugwiritsidwa ntchito kwa Telsartan muukalamba kulibe mawonekedwe pokhapokha pakuchita zotsutsana mwa odwala.
The ntchito aimpso kuwonongeka
Kuchepa kwa ntchito yaimpso kumabweretsa chakuti gawo lothandizila la wothandizira limamangirira ku plasma peptides ndi 100%. Kuchotsa telmisartan mu mawonekedwe ofatsa komanso olimbitsa aimpso sasintha.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Ndi kufatsa kochepa kwambiri kwa chiwindi, mlingo wa tsiku ndi tsiku wa mankhwalawa suyenera kupitirira 40 mg.
Mankhwala osokoneza bongo a Telsartan 80
Zambiri pa bongo ndizochepa. Hypotension, kuthamanga kapena kuchepa kwa kugunda kwa mtima nkotheka.
Ngati mukukayikira kuchuluka kwa telmisartan, muyenera kufunsa dokotala. Pankhaniyi, mankhwala othandizira amalimbikitsidwa. Hemodialysis siyothandiza.
Kuchita ndi mankhwala ena
Chipangizochi chimatha kugwiritsa ntchito mankhwala ena a antihypertensive.
Kuphatikizidwa kwa Telsartan ndi ma statins, paracetamol sikumabweretsa kuwoneka kwa zoyipa zilizonse.
Chidachi chitha kuwonjezera kuchuluka kwa mphamvu ya digoxin m'magazi. Izi zimafuna kuwunikira.
Sitikulimbikitsidwa kugwiritsa ntchito Telsartan yokhala ndi potaziyamu woletsa mankhwala ndi mankhwala, omwe ndi othandizira omwe ndi potaziyamu. Kuphatikiza koteroko kumatha kuyambitsa Hyperkalemia.
Kuphatikiza ndi kukonzekera komwe kumakhala ndi mchere wa lithiamu kumawonjezera poizoni wawo. Kugwiritsa ntchito kuphatikiza koteroko ndikofunikira pokhapokha kuyang'anitsitsa mosamala zinthu za lithiamu zomwe zili m'magazi.
Acetylsalicylic acid ndi mankhwala ena osapweteka a antiidal angachepetse mphamvu ya mankhwalawa. NSAIDs yomwe imalepheretsa ntchito ya cycloo oxygenase kuphatikiza ndi telmisartan imatha kuyambitsa mawonekedwe aimpso zamagulu ena.
Acetylsalicylic acid ndi mankhwala ena osapweteka a antiidal angachepetse mphamvu ya mankhwalawa.
Systemic glucocorticosteroids amachepetsa mphamvu ya antihypertensive mankhwala.
Kuyenderana ndi mowa
Sitikulimbikitsidwa kumwa mowa wamtundu uliwonse mukamamwa ndi Telsartan.
Analogi
Ma Analogs a chida ichi ndi:
- Mikardis;
- Wotsogolera;
- Telmisartan-Ratiopharm;
- Telpres
- Telmista;
- Tsitsi
- Hipotel.
Kupita kwina mankhwala
Amamasulidwa malinga ndi zomwe dokotala wanena.
Kodi ndingagule popanda kulandira mankhwala?
Ayi.
Mtengo wa Telsartan 80
Mtengo wa ndalama zimadalira malo ogula.
Zosungidwa zamankhwala
Iyenera kusungidwa m'malo owuma pa kutentha osaposa + 25 ° C.
Tsiku lotha ntchito
Chogulacho ndi choyenera kugwiritsidwa ntchito patatha zaka ziwiri kuyambira tsiku lomwe adamasulidwa.
Wopanga
Mankhwalawa amapangidwa ndi kampani yaku India ya Reddis Laboratories Ltd.
Mankhwala a Telsartan amaperekedwa mu mankhwala okha ndi mankhwala.
Ndemanga pa Telsartan 80
Madokotala
Grigory Koltsov, katswiri wazaka 58, Tula
Mankhwala abwino omwe amathandiza kuthana ndi mawonekedwe a matenda oopsa. Ndimapereka kwa odwala onse omwe ali ndi digiri yofatsa, komanso m'malo ovuta kwambiri. Ndiotetezeka, zotsatira zoyipa ndizosowa. Kupatula akhoza kukhala anthu omwe ali ndi vuto la impso kapena kwa chiwindi. Zikatero, ndimapita kukacheza mosamala kwambiri.
Artem Yanenko, wothandizira, wazaka 41, Moscow
Njira yotsika mtengo kwa amene amafunikira kuyang'anira kuthamanga kwa magazi awo. Ngakhale kuti malonda adapangidwa ku India, osati ku Germany kapena dziko lina la ku Europe, mtundu wake umakwaniritsa zoyembekezera.
Kusankha mlingo woyenera kumathandizira kuthandizira popanda zovuta. Sindikulimbikitsa kuyamba mankhwalawo. Kudzilimbitsa nokha kumatha kudzetsa thanzi, chifukwa chake onetsetsani kuti mwakumana ndi katswiri musanayambe chithandizo.
Odwala
Arina, wazaka 37, Ulyanovsk
Ndidamwa mankhwalawa mpaka chilimwe chatha. Ndakhala ndikudwala matenda oopsa kuyambira ndili mwana, motero ndimakonda kugwiritsa ntchito mapiritsi.
Chilimwe chatha, ndinayenera kusiya Telsartan nditapita kuchipatala cha gynecologist. Dotolo adatsimikiza kuti ndili ndi pakati. Adanenanso kuti pa nthawi yoyembekezera, makamaka munthawi yoyambira, mankhwalawa sayenera kumwa. Ndidayenera kupita kwa katswiri kuti ndilowetse mankhwalawo.
Nditamaliza kudyetsa mwana, ndiyambanso kumwa Telsartan.Chida ichi chimagwirizana kwathunthu ndi ntchito yake. Zotsatira zoyipa sizinawonedwe panthawi yoyang'anira.
Victor, wazaka 62, Moscow
Ndimamwa mankhwalawa nthawi zonse. Kwa zaka zambiri, ndimadwala matenda a impso komanso matenda oopsa. Chaka chatha, impsoyo idayenera kusinthidwa chifukwa idakana kwathunthu, ndipo yachiwiri siyidayeretse iyo yokha.
Pambuyo pochotsa impso, mavuto ang'onoang'ono adayamba. Kusintha kudawonekera. Anadutsa mayeso kuti amvetse zomwe zimachitika. Dokotalayo adalongosola kuti khunyu idachitika chifukwa cha kuchuluka kwa potaziyamu m'magazi. Ndinayenera kusiya Telsartan kwakanthawi. Pambuyo pake, adabwereranso ku phwando. Kwazaka zambiri zogwiritsidwa ntchito, palibe zodandaula zomwe zabuka. Nditha kulimbikitsa kwa anthu onse omwe ali ndi matenda oopsa.
Evgenia, wazaka 55, St. Petersburg
Miyezi ingapo yapitayo, adotolo adapereka chithandizo ichi. Posachedwa ndidapezeka kuti ndili ndi matenda oopsa, choncho sindinamwe mankhwala aliwonse kale.
Mavuto adayamba kuyambira masiku oyambilira a Telsartan. Panali nseru, dyspepsia. Khungu lidakonkhedwa ndi ziphuphu zazing'ono. Ndinapita kwa adotolo. Anandifotokozera kuti ndimalekerera mankhwalawo. Ndidayenera kuyang'ana m'malo. Sindingathe kuvomereza Telsartan, popeza sizomwe zimakondweretsa kwambiri zomwe zimagwirizanitsidwa ndi izi.
