Milgamma ndi kukonzekera komwe kumapangidwa ndi mavitamini a B. Chochita ichi chimabwezeretsa maselo am'mitsempha, omwe amalola kuti agwiritsidwe ntchito pochiza matenda amitsempha osiyanasiyana. Zilonda zimatengeka mosavuta, ndipo chinthucho chimaponyedwa kuchokera m'thupi maola ochepa.
Dzinalo Losayenerana
Benfotiamine ndi pyridoxine - dzina la magwiritsidwe ake a mankhwalawa.
ATX
A11DB - code for anatomical and achire mankhwala gulu.
Milgamm - mankhwala olemera ndi mavitamini a gulu B.
Kupanga
Piritsi 1 ili ndi zinthu zotsatirazi: 100 mg ya benfotiamine ndi kuchuluka kofanana kwa pyridoxine hydrochloride (vitamini B6). Popanga zinthu izi:
- ma cellcose a microcrystalline;
- omega-3-glycerides;
- povidone;
- colloidal silicon dioxide;
- carmellose sodium;
- talcum ufa.
Chipolopolocho chimaphatikizapo:
- sucrose;
- chipolopolo;
- calcium carbonate;
- chingamu;
- titanium dioxide;
- silika;
- wowuma chimanga;
- glycerol;
- macrogol;
- polysorbate;
- glycol sera.
Mu gulu limodzi la khungu lili ndi miyala 15.
Zotsatira za pharmacological
Benfotiamine (mafuta osungunuka ena otuluka a thiamine) amasintha kagayidwe kazachilengedwe. Thupi limaphatikizidwa ndi kagayidwe kazakudya zomanga thupi pamaselo a ma cell, zimathandizira kuti mafuta abwinidwe, amagwira ntchito ngati antioxidant wabwino. Mtundu wa neuroactive wa thiamine ndi thiamine triphosphate. Chifukwa cha mankhwalawa, kayendedwe kabwinobwino ka mitsempha kamatsimikiziridwa, mankhwalawa amakhala ndi analgesic, amasintha magazi.
Pyridoxine imagwira ntchito ngati cofactor (yopanda mapuloteni), yomwe imatenga mbali muzinthu zambiri za enzymatic zomwe zimachitika minyewa yamitsempha. Vitamini B6 amagwiritsidwa ntchito ngati cholimbikitsa pothandizira matenda osachiritsika ndi amitsempha yotupa, kusokonezeka kwa magwiridwe antchito a zida zamagetsi.
Pyridoxine imasintha kaphatikizidwe ka ma neurotransmitters monga adrenaline, norepinephrine, dopamine, histamine. Chinthu chimagwira ntchito monga:
- decarboxylation wa amino acid, kusintha kwawo;
- kupewa kwambiri kupanga ammonia;
- kusinthika kwa kulumikizana kwa mitsempha.
Pharmacokinetics
Benfotiamine amalowetsedwa kudzera m'mimba. Kuzindikira kwakukulu kwa chinthu kumawonedwa ola limodzi mutatha kumwa mankhwalawa. Mtundu wosungunuka wa vitamini B1 umalowetsedwa ndi thupi mwachangu kwambiri kuposa madzi osungunuka a madzi. Izi zimasinthidwa kukhala thiamine diphosphate pambuyo pa biotransformation. Pambuyo pake, imakhala yofanana ndi thiamine. Thiamine diphosphate ndi coenzyme wa pyruvate decarboxylase, amagwira ntchito mukubwadamuka.
Ambiri a pyridoxine amadziwikitsidwa kumtunda kwam'mimba thirakiti panthawi yakayamwa. Kamodzi m'magazi, amasinthidwa kukhala pyridoxalphosphate ndikupanga mgwirizano wokhazikika ndi albumin. Asanalowe mu cell, chinthucho chimapangidwira hydrolyzed ndi alkaline phosphatase.
Mavitamini onsewa amathandizidwa ndi urea. Thiamine imalumikizidwa kwathunthu ndi theka, enawo amachotsedwa mu mawonekedwe ake oyambayo. Benfotiamine amachotsedwa theka kuchokera m'magazi pambuyo maola 3.6, ndi pyridoxine - atatha maola 2-5.
Kodi chimathandiza ndi chiyani mapiritsi a Milgamm?
Mankhwalawa agwira ntchito mochizira matenda otsatirawa:
- neuritis ndi neurosis yoyambitsidwa ndi kuchepa kwa mavitamini B1 ndi B6;
- polyneuropathy, neuropathy;
- radicular syndromes;
- myalgia;
- herpes zoster;
- retrobulbar neuritis;
- ganglionitis;
- zotupa za nkhope
- kuchuluka;
- lumbar ischalgia;
- zokhudza minyewa yamitsempha yam'mimba;
- radiculopathy.
Chida chimathandizira kuthana ndi kukokana pakamagona, ma syndromes osiyanasiyana a minofu.
Contraindication
Mankhwalawa amaletsedwa kugwiritsidwa ntchito mwazinthu zingapo:
- Hypersensitivity munthu zikuluzikulu za mankhwala;
- kulephera kwa mtima, kuphatikizapo gawo la kubwezera;
- mudakali ana.
Mlingo ndi kasamalidwe ka mapiritsi a Milgamm
Ndi bwino kumwa mankhwala mukatha kudya, mapiritsi 1-2 katatu patsiku. Chomwechicho chimayenera kumizidwa ndi madzi ambiri. Kutalika kwa chithandizo ndi milungu 4.
Ndi matenda ashuga
Milgamma mapiritsi ntchito mankhwalawa matenda a shuga. Anthu odwala matenda ashuga amatha kumwa mankhwalawa piritsi limodzi katatu patsiku, ngati pangafunike kuthetseratu kupweteka. Monga mankhwala okonza, mutha kumwa piritsi limodzi patsiku.
Mankhwala ali contraindised mu mtima kulephera.
Zotsatira zoyipa za mapiritsi a Milgamm
Matumbo
Pafupipafupi, nseru imachitika ndikumwa mankhwalawa, ndipo nthawi zina amasintha kukhala kusanza.
Pakati mantha dongosolo
Chifukwa chogwiritsa ntchito mankhwalawa kwa nthawi yayitali (kupitirira miyezi 6), zotumphukira za m'mitsempha ya m'mimba zimayamba. Maonekedwe a zizindikiro monga:
- kupweteketsa mutu;
- chizungulire, chisokonezo;
- kutuluka thukuta kwambiri.
Kuchokera pamtima
Nthawi zina, mankhwalawa amakhumudwitsa kukula kwa tachycardia.
Kuchokera ku chitetezo chamthupi
Zotsatira zotsatirazi zitha kuchitika mwa anthu oopsa:
- zotupa pakhungu, kuyabwa, urticaria, kufupika kwa mpweya;
- Edema ya Quincke ndi kugwedezeka kwa anaphylactic.
Zokhudza mphamvu pakuwongolera njira
Mankhwalawa samakhudza kuchuluka kwa momwe amagwirira ntchito ndipo samawonongetsa chidwi chomwe chikufunika pakuwongolera njira zake.
Matupi omaliza
Kutengera komwe kumamwa mankhwalawa, ziphuphu zitha kuwoneka. Nthawi zina redness ya dermis imawonedwa, ndipo moto woyaka umamveka m'malo ena a khungu.
Malangizo apadera
Kupatsa ana
Chifukwa cha kusowa kwa chidziwitso cha mankhwalawa pazokhudzana ndi mankhwalawa pa thupi la ana, mankhwalawa saikidwa kwa ana.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Mankhwalawa ali ndi 100 mg ya pyridoxine, womwe ndiwokwera kanayi kuposa momwe amapangira vitamini tsiku lililonse panthawi yoyembekezera. Pazifukwa izi, akatswiri samapereka mankhwalawa kwa amayi apakati komanso oyamwa.
Bongo
Mankhwala osokoneza bongo ndi osowa kwambiri. Imadziwoneka yokha mwa mawonekedwe a neurotoxic omwe amapitilira kwakanthawi kochepa. Ngati kuchuluka kwa mankhwalawa kumachitika pafupipafupi kwa miyezi 6 kapena kupitirira apo, wodwalayo angamve kupweteka kwam'mitsempha, komwe kumayendetsedwa ndi ataxia. Mankhwala osokoneza bongo amachititsa kugwidwa.
Kuchita ndi mankhwala ena
Ndikofunikira kuganizira izi:
- Thiamine imapangidwa ndi sulfates.
- Mankhwala Levodopa amachepetsa kugwiritsa ntchito mankhwalawa ndi vitamini B6.
- Imachepetsa mphamvu ya mavitamini redox zinthu, riboflavin, phenobarbital, metabisulfite.
- Kuwonongeka kwa thiamine kumapangitsa kuti pakhale mkuwa. Zomwe zimagwiritsidwa ntchito ndi wothandizirazo zimasiya kugwira ntchito ngati pH imaposa 3.
- Ma antioxidants amachepetsa kuchuluka kwa photolysis, nicotinamide - imawonjezeka.
Ndi bongo wosakhalitsa, wodwalayo amatha kukhala ndi neuropathy, limodzi ndi ataxia.
Kuyenderana ndi mowa
Ethanol imayambitsa kusowa kwa vitamini B6. Kumwa mowa mukamalandira chithandizo sikulimbikitsidwa.
Analogi
Milgamma Compositum imapezekanso mwa njira yothetsera jakisoni. Mankhwala otsatirawa a analogue alipo: Neuromultivit, Polyneurin, Neurobeks, Neurorubin, Combilipen, Triovit, Neurobeks Forte.
Kodi pali kusiyana kotani pakati pa mapiritsi ndi mapiritsi a Milgamm?
Mankhwala onse omwe ali ndi mitundu ya mankhwalawa ali ndi zofanananso zochizira. Mapiritsi amatengedwa pamaso pa matenda amitsempha omwe amayamba chifukwa cha kusowa kwa mavitamini a gulu B. Mitsempha yake imathandizira kwambiri pakuthandizira matenda a neuritis, neuralgia.
Triovit ndi analogue ya Milgamma.
Kupita kwina mankhwala
Milgamma amatanthauza mankhwala opitilira apo.
Zikwana ndalama zingati?
Mtengo wapakati wa Milgamm mu mawonekedwe a dragee ndi ma ruble 1000.
Zosungidwa zamankhwala
Mankhwalawa amayenera kusungidwa pamatenthedwe mpaka 25 ° C, osapezekanso ndi ana.
Tsiku lotha ntchito
Mankhwala amakhalanso ndi mphamvu yochiritsa kwa zaka 5.
Wopanga
Mankhwalawa amapangidwa ndi kampani yaku Germany ya Worwag Pharma.
Ndemanga
Madokotala
Victor, wazaka 50, Moscow
Mankhwalawa atsimikizira kuti ndi othandizadi kuchiza kupweteka kwa msana, osteochondrosis. Nditatha kumwa Vitamini, odwala anga amayenda bwino. Chobweretsera chokha ndi chida chachikulu.
Dmitry, wazaka 45, St. Petersburg
Ndimasankha Milgamma kukhala odwala neuralgia. Mankhwalawa amathandiza anthu pamavuto.
Odwala
Natalya, wazaka 26, St. Petersburg
Anatenga Milgamm pa mankhwala a neuralgia a patostal. Zilonda ndizosavuta kutenga, chifukwa zitha kunyamulidwa nanu nthawi zonse. Mutha kugula mankhwala ku pharmacy iliyonse. Zilibe kuvulaza thupi.
Mira, wazaka 25, Kazan
Dokotala adapereka mankhwala othandizira ovuta a msana wa thoracic. Kutopa kwa minofu kwapita, kupweteka kumachepa.
