Hemeni ya insulin imapangidwa ndikusungidwa ndi kapamba. Maselo ake akadzalephera kupanga insulin yokwanira, matenda monga matenda amtundu 1 amayamba. Shuga owonjezera, yemwe amadzikwana m'magazi, ndi owopsa m'thupi. Chimodzi mwazomwe zimagwiritsidwa ntchito pobwereza insulin ndi Insugen R.
Dzinalo Losayenerana
Insulin (munthu) (Insulin (munthu)).
Chimodzi mwazomwe zimagwiritsidwa ntchito pobwereza insulin ndi Insugen R.
ATX
A10AB - Insulin ndi mawonekedwe a jekeseni, kuchitapo kanthu mwachangu.
Kutulutsa mafomu ndi kapangidwe kake
Kuyimitsidwa kwa jakisoni, 40 MO / ml, mu 10 ml m'mabotolo No. 10, No. 20, No. 50, No. 100.
Kuyimitsidwa kwa jakisoni, 100 MO / ml, mu 10 ml m'mabotolo No. 10, No. 20, No. 50, No. 100, 3 ml m'makatoni No. 100.
Zotsatira za pharmacological
Kubwezeretsanso njira yochepetsera insulin yaumunthu.
Insulin imayang'anira kagayidwe kazigawo m'thupi. Hormone imeneyi imachepetsa kuchuluka kwa shuga m'magazi polimbikitsa kukoka kwa glucose omwe amapanga maselo amthupi (makamaka mafupa am'mimba ndi mafuta minofu) ndikuletsa gluconeogeneis (kaphatikizidwe ka glucose pachiwindi).
Odwala omwe ali ndi matenda a shuga, mankhwalawa amathandizira m'njira yoyenera ya njira zonse, amachepetsa chiopsezo cha zovuta zomwe zimachitika ndi matendawa.
Mukamagwiritsa ntchito mankhwalawa, muyenera kuyang'anira kuchuluka kwa shuga m'magazi.
Pharmacokinetics
Mankhwalawa amayamba kugwira ntchito pasanathe mphindi 30. Kuchuluka kwake kumachitika pambuyo pa maola 2-4. Kutalika kwa chochita: kuchokera 4 mpaka 6 maola.
Hafu ya moyo wa insulini m'magazi ndi mphindi zingapo. Izi zimakhudzidwa ndi zinthu zingapo: Mlingo wa insulin, tsamba la jakisoni.
Zizindikiro zogwiritsidwa ntchito
Chithandizo cha matenda osokoneza bongo a mellitus 1 ndi 2.
Mankhwalawa amagwiritsidwa ntchito pa mtundu 1 komanso matenda a shuga a 2.
Contraindication
Mkhalidwe wa hypoglycemia. Hypersensitivity ya wodwalayo insulin kapena gawo lina la mankhwala.
Ndi chisamaliro
Kusamala ndikofunikira mukamagwiritsa ntchito mankhwalawa amayi apakati (zosakwanira pazomwe mungagwiritse ntchito pa nthawi ya pakati).
Sizikudziwika ngati insulin imachotsedwa mkaka wa amayi. Mukamayamwitsa, kusintha kwa mankhwalawa kwa mankhwala ndi zakudya nthawi zina kumafunikira.
Momwe mungatengere Insugen R
Amabayidwa pansi pakhungu pakhungu la adipose pamimba, ntchafu kapena phewa. Kuti lipodystrophy isathere, tsamba la jakisoni liyenera kusinthidwa jekeseni iliyonse.
Poyerekeza ndi jakisoni mbali zina za thupi, mankhwalawo amamwetsedwa mwachangu akaphatikizidwa mu minofu ya adipose yam'mimba.
Mankhwalawa amalowetsedwa pansi pakhungu kupita m'matumbo a adipose pamimba, ntchafu kapena phewa.
Mankhwala saloledwa kulowa mitsempha.
Ndi matenda ashuga
Mlingo wa mankhwalawa umasiyanasiyana pakati pa 0.5-1 IU / kg patsiku ndipo amawerengedwa payekhapayekha, poganizira kuchuluka kwa shuga m'magazi a wodwala aliyense.
Mankhwalawa amatumizidwa 1-2 pa tsiku, theka la ola musanadye chakudya chamafuta ambiri.
Kutentha kwa njira yovulazirayo kuyenera kukhala + 18 ... + 25 ° C.
Musanagwiritse jakisoni, muyenera:
- Onetsetsani kuti maphunziro omwe atchulidwa pa syringe ndi ofanana ndi kuchuluka kwa insulini yosindikizidwa pamtunda: 40 IU / ml kapena 100 IU / ml.
- Gwiritsani ntchito syringe kokha ndi kumaliza maphunziro omwe ali ofanana ndi kuchuluka kwa insulini mu vial.
- Gwiritsani ntchito ubweya wa thonje wokhazikika mu mowa wamankhwala kuti mutemerere vial.
- Kuti muwonetsetse kuti yankho m'botolo likuwonekera ndipo palibe zodetsa zina mkati mwake, muyenera kulipukusa pang'ono. Ngati zosafunika zilipo, ndiye kuti mankhwalawo ndi osayenera kugwiritsa ntchito.
- Sungani mpweya wambiri mu syringe monga momwe zimakhalira ndi insulin.
- Lowetsani mpweya mu vial ya mankhwala.
- Sansani botolo kenako jambulani insulini yoyenera mu syringe.
- Onani ngati mu syringe ndi muyezo wabwino.
Dongosolo loyambira:
- muyenera kugwiritsa ntchito zala ziwiri kukoka khungu, ndikuyika singano pansi pake kenako kubaya mankhwalawa;
- sungani singano pansi pa khungu kwa masekondi 6 ndikuonetsetsa kuti zomwe zili mu syringe zimayikidwa popanda chotsalira, chotsani;
- mukamagawa magazi kuchokera m'malo a jakisoni pambuyo pa jakisoni, kanikizani malowa ndi chidutswa cha ubweya wa thonje.
Ngati insulini ili m'makatoni, ndiye kuti muyenera kugwiritsa ntchito cholembera chapadera molingana ndi malangizo ake kuti mugwiritse ntchito. Kugwiritsanso ntchito katiriji sikuloledwa. Phata limodzi la syringe liyenera kugwiritsidwa ntchito ndi munthu m'modzi. Ndikofunikira kutsatira mosamalitsa malangizo ogwiritsa ntchito cholembera.
Zotsatira zoyipa za Insugen R
Pogwiritsa ntchito mankhwalawa, zotsatira zoyipa zingapo zingachitike:
- mogwirizana ndi kagayidwe kazakudya: hypoglycemia (kuchuluka kwa thukuta, kufooka kwa khungu, kunjenjemera kapena mantha, kuchepa kwa chidwi, nkhawa, kutopa kapena kufooka, chizungulire, njala yayikulu, nseru, kuchuluka kwa mtima; ndi hypoglycemia, kupsinjika ndi kutayika kumachitika. kuzindikira;
- thupi lawo siligwirizana: pafupipafupi - urticaria, zotupa pakhungu, kawirikawiri - anaphylaxis;
- zimachitika mderalo mu mawonekedwe a ziwengo (redness of the khungu, kutupa, kuyabwa pamalowo jekeseni), nthawi zambiri munthawi yamankhwala amadziletsa, lipodystrophy imayamba;
- ena: kumayambiriro kwa chithandizo, kawirikawiri - zovuta zingapo za edema, zolakwika zosatsimikizika zimachitika.
Mukamagwiritsa ntchito insulin, mavuto amabwera molingana ndi mlingo ndipo zimachitika chifukwa cha insulin.
Zokhudza mphamvu pakuwongolera njira
Hypoglycemia yomwe imayamba imatha kubweretsa kuwongolera pakutha kuyendetsa galimoto ndikusokoneza zochitika zina pazowopsa, zomwe zimafunikira chidwi chochulukirapo komanso malingaliro osachedwa m'maganizo ndi magalimoto.
Malangizo apadera
Odwala ena amafunikira kutsatira malamulo angapo apadera a chithandizo cha insulin.
Gwiritsani ntchito mu ukalamba
Kwa odwala okalamba, mlingo wa mankhwalawa umayenera kusinthidwa.
Kupatsa ana
Mlingo wa insulini umaperekedwa kwa mwana aliyense malinga ndi zofunikira za shuga m'magazi, poganizira zosowa za thupi lake.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Chifukwa chakuti insulin siyidutsa mu placenta, palibe zoletsa komanso zoletsa kuti zigwiritsidwe ntchito ndi amayi oyembekezera.
Asanakhale ndi pakati komanso panthawi yonse yovomerezeka, thanzi la mayi yemwe wapezeka ndi matenda a shuga liyenera kuyang'aniridwa, kuphatikizapo kuwongolera kwa shuga m'magazi.
Kufunika kwa insulin kwa mayi wapakati kumachepa mu 1 trimester, ndipo mu 2nd ndi 3 trimesters ndikofunikira kuti ayambe kuyendetsa mahomoni awa. Mukadutsa ntchito ndipo pambuyo pawo, mayi wapakati angafunikire insulin itha kuchepa mwadzidzidzi. Pambuyo pobereka, thupi la mkazi limafunikira kwa timadzi timeneti timakhala momwe timakhalira mimbayo. Pa yoyamwitsa, insulin imagwiritsidwa ntchito popanda zoletsa (insulin ya mayi woyamwitsa sichimavulaza mwana). Koma nthawi zina kusintha kwa mlingo kumafunika.
Mankhwala samadutsa mkaka wa m'mawere.
The ntchito aimpso kuwonongeka
Panthawi ya ziwalozi, vuto la insulin yambiri limayamba. Popeza awonongeka mu impso, ndi kukanika kwawo, sangathe kupanga insulin. Imakhala m'magazi kwa nthawi yayitali, pomwe maselo amatenga glucose kwambiri. Chifukwa chake, kusintha kwa mlingo ndikofunikira.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Monga impso, chiwindi chimawononga insulin. Chifukwa chake, ndi kukanika kwake, kusintha kwakofunikira ndikofunikira.
Mankhwala osokoneza bongo a Insugen P
Zizindikiro za mankhwala osokoneza bongo ndi zotsatira za hypoglycemia (thukuta kwambiri, nkhawa, kufooka kwa khungu, kunjenjemera kapena kusangalala kwambiri kwa mantha, kumva kutopa kapena kufooka, chizungulire, kuchepa kwa ndende, kumva kutchulidwa kwamvuto lanjala, nseru, ndi kuchuluka kwa mtima).
Mankhwala osokoneza bongo: wodwala amatha kuthana ndi vuto la shuga: pakudya shuga wokhala ndi shuga: shuga kapena zakudya zina zopatsa mphamvu zamkati (tikulimbikitsidwa kuti nthawi zonse mumakhala ndi shuga kapena maswiti ena nanu). Mu hypoglycemia yayikulu, wodwalayo akapanda kuzindikira, yankho la 40% dextrose ndi glucagon wa mahormone (0.5-1 mg) amalowetsa mtsempha. Wodwalayo akayambanso kudziwa kuti hypoglycemia isadzachitikenso, amalimbikitsidwa kuti azidya zakudya zapamwamba kwambiri.
Kuchita ndi mankhwala ena
Fenfluramine, cyclophosphamide, clofibrate, Mao inhibitors, ma tetracyclines, kukonzekera kwa anabolic steroid, sulfonamides, osagwiritsa ntchito beta-blockers, omwe amakhala ndi ethyl mowa, amatsogolera pakuwonjezeka kwa hypoglycemic effect (shuga-kuchepetsa-insulin).
Thiazide diuretics, heparin, tridclic antidepressants, kukonzekera kwa lithiamu, mahomoni a chithokomiro, glucocorticoids, kulera kwapakamwa kumabweretsa kufooka kwa zotsatira za hypoglycemic.
Pogwiritsa ntchito salicylates kapena reserpine yophatikiza ndi insulin, zotsatira zake zimatha kukula ndikuchepa.
Analogi
Zofanana muzochitika ndi mankhwala monga
- Actrapid NM;
- Protafan NM;
- Thawitsani;
- Humulin Wokhazikika.
Kuyenderana ndi mowa
Mowa wa Ethyl ndi mankhwala ophera majakisoni angapo omwe amapezeka nawo angayambitse insulin.
Kupita kwina mankhwala
Chipangizocho chitha kugulidwa kokha ndi mankhwala.
Kodi ndingagule popanda kulandira mankhwala?
Awa ndi mankhwala a mahomoni, motero samaperekedwa popanda kulandira mankhwala.
Mtengo wa Insugen R
Mtengo umasiyanasiyana pakati pa ma ruble 211-1105. Kuyambira 7 mpaka 601 UAH. - ku Ukraine.
Zosungidwa zamankhwala
Chogulirachi chikuyenera kusungidwa pa kutentha kwa + 2 ... + 8 ° C, kupewa kuzizira. Ana sayenera kulandira mankhwala.
Chogulirachi chikuyenera kusungidwa pa kutentha kwa + 2 ... + 8 ° C, kupewa kuzizira. Ana sayenera kulandira mankhwala.
Tsiku lotha ntchito
Moyo wa alumali ndi miyezi 24.
Mankhwalawa ayenera kugwiritsidwa ntchito pakatha milungu isanu ndi umodzi atayamba kugwiritsa ntchito botolo litasungidwa pa kutentha kosaposa + 25 ° C.
Ngati tsiku lotha ntchito lomwe lasonyezedwa pa ma CD latha, mankhwalawo aletsedwa kugwiritsa ntchito. Ngati mutagwedeza yankho mu vial kapena pamakhala mitambo kapena pali zosayenera zina zilizonse, mankhwalawo amaletsedwa kugwiritsa ntchito.
Wopanga
Biocon Limited, India.
Ndemanga za Insugen R
Venus, wa zaka 32, Lipetsk
Madokotala amayika mapiritsi a agogo anga a shuga ambiri, ndipo amalume anga nthawi zonse amadzipatsa jakisoni wololedwa ndi dokotala. Imodzi mwa jakisoni ndi Insugen.
Izi zikutanthauza kuti amalume amadzibaya kangapo patsiku, machitidwewo sakhalitsa. Koma amayamika mankhwalawo. Kuphatikiza apo, amatenga mitundu ingapo yamankhwala.
Zotsatira za mankhwalawa ndi zabwino, koma amafunika kuthandizidwa pokhapokha atakambilana ndi katswiri ndikuwunika.
Elizabeth, wazaka 28, Bryansk
Agogo anga aakazi akhala ndi matenda ashuga kwa zaka zambiri. Mu 2004, adalandira insulin. Yesani kugwiritsa ntchito mankhwala osiyanasiyana. Madokotala amatopa ndikusankha yoyenera. Kenako adanyamula Insugen.
Mlingo wofunika uliwonse uli ndi wawo. Agogo anasankha kuchuluka kwa dokotala. Tikufuna mankhwalawa. Ndikupangira mankhwalawa kwa aliyense, kwa ife ndi mtundu woyenera kwambiri wa insulin. Koma ndibwino kufunsa katswiri kaye. Ichi ndi chida champhamvu kwambiri kuti popanda kuyang'aniridwa ndi dokotala simuyenera kuyambitsa nokha chithandizo.
Olga, wazaka 56, Yekaterinburg
Mankhwala abwino, oyenera kulumpha mwamphamvu ndi lakuthwa mu glucose wamagazi. Mankhwalawa amagwira ntchito patatha mphindi 30 jakisoni atapangidwa. Zotsatira zake zimakhala pafupifupi maola 8. Madotolo adati iyi ndi mtundu woyenera kwambiri wa insulin. Koma zingakhale bwino kwambiri ngati siziyenera kudulidwa, koma kumwa mapiritsi.
Timofey, wazaka 56, Saratov
Ndadwala matenda ashuga pafupifupi zaka makumi atatu. Ndimagwiritsa ntchito insulin yomweyo. Poyamba, adalowetsa Humulin R ndi mitundu ina. Komabe, sanasangalale. Ngakhale poganiza kuti shuga anali wabwinobwino.
Posachedwa Insugen. Kugwiritsa ntchito kwa masiku angapo, ndinazindikira kuti thanzi langa linali labwino. Kumva kutopa ndi kugona kumatayika.
Sindilimbikira mwanjira iliyonse, koma ndikuganiza kuti mankhwalawa ndiye apamwamba kwambiri.
