Tricor 145 ndi wothandizira pakamwa wa hypolipidemic womwe umagwiritsidwa ntchito pazachipatala kuti muchepetse cholesterol yambiri ndi triglycerides. Kuchotsa kwa hypercholesterolemia ndikofunikira kuti muchepetse chiopsezo cha atherosulinosis ndikuletsa mapangidwe a malo a atherosranceotic pamakoma a chotengera. Mankhwala amachepetsa chiwopsezo cha kuundana kwa magazi chifukwa chokakamira kuphatikizika kwa maselo amwazi.
Dzinalo Losayenerana
Fenofibrate.
Tricor 145 imagwiritsidwa ntchito kutsitsa cholesterol yayikulu ndi triglycerides.
ATX
C10AB05.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwalawa amapezeka m'miyala yoyera pakamwa. Gawo lililonse la mankhwalawa lili ndi 145 mg yogwira mankhwala - fenofibrate nanoparticles. Zotsatirazi zimagwiritsidwa ntchito kuti chiwonjezere liwiro komanso kufalikira kwathunthu molumikizana ndi chinthu chogwira:
- crospovidone;
- hypromellose;
- ma cellcose a microcrystalline;
- sodium lauryl sulfate ndi ma script;
- shuga mkaka, sucrose;
- colloidal dehydrate silicon dioxide;
- magnesium wakuba.
Tricor 145 imapezeka m'magome oyera a pakamwa pakamwa ndipo ili ndi 145 mg yogwira - fenofibrate nanoparticles.
Mapiritsiwo amakutidwa ndi membrane wa filimu pamwamba, yemwe amasungunuka pansi pa zochita zamatumbo. Kanemayo amakhala ndi mowa wa polyvinyl, titanium dioxide, talc, soya lecithin, chingamu cha xanthan.
Ma fomu omwe palibe:
- msuzi;
- jakisoni mu ampoules.
Zotsatira za pharmacological
Mankhwala a hypoglycemic ndi a gulu la fibrate. Makina a zochita za pawiri yogwira amatengera kutseguka kwa alpha receptors. Chifukwa chakuwonjezera ntchito yawo yogwira ntchito, lipolysis ndi excretion ya lipoprotein yokhala ndi triglycerides yambiri imalimbikitsidwa.
Fenofibrate imapangidwa kuchokera ku fibric acid, yomwe imatha kukhudza mulidi wa lipids m'thupi la munthu chifukwa cha kuyambitsa kwa alpha receptors. Chifukwa chakuchita bwino kwa mankhwalawa, kuchuluka kwa lipoproteins yotsika kwambiri (LDL) kumachepetsedwa ndipo kachigawo kakakulu kachulukidwe (HDL) kakulitsidwa. Mayeso oyesera adawonetsa kuchepa kwa cholesterol yathunthu ndi 25%, triglycerides ndi 45-55% komanso kuwonjezeka kwa ndende ya HDL ndi 10-30%.
Munthawi yamankhwala othandizira, chiopsezo chotengera kusintha kwa ma atherosselotic mu vasotor endothelium imachepetsedwa ndipo mwayi wopanga cholesterol plaques pamakoma amitsempha amachepa. Ndi kugwiritsa ntchito mankhwalawa kwa nthawi yayitali, kuchuluka kwa zothandizira kumachepa. Pamaso pa hyperuricemia, odwala amalandila mwayi wowonjezereka ngati 25% ya uric acid.
Tricor 145 - mankhwala a hypoglycemic ndi a gulu la mafupa.
Pharmacokinetics
Akalowa m'matumbo, mapiritsiwa amawongolera ndi ma protein kuti apange fenofibroic acid. Mankhwalawa amasiyana m'magazi, pomwe amafikira pazofunikira zambiri mkati mwa maola 2-4. Yogwira kagayidwe kachakudya imalowa mu khoma lamatumbo momwe muli nanoparticles, kotero, kugwiritsidwa ntchito kwa chakudya sikukukhudza kuchuluka kwa mayamwa komanso kukwaniritsidwa kwa bioavailability. M'mitsempha yamagazi, 99% yogwira fenofibroic acid imapanga zovuta ndi plasma albin.
Zinthu zamankhwala sizisintha m'maselo a chiwindi. Hafu ya moyo wa metabolite yogwira ndi maola 20. Mankhwalawa amasiya thupi ndi mkodzo mkati mwa sabata limodzi.
Zizindikiro zogwiritsidwa ntchito
Mankhwalawa amagwiritsidwa ntchito kukhathamiritsa cholesterol ndi triglycerides kapena dyslipidemia wochepetsedwa ndi chithandizo chamankhwala, kuwonjezera zolimbitsa thupi ndi njira zina zosagwiritsa ntchito mankhwalawa polimbana ndi kunenepa kwambiri. Makamaka pamaso pa ochepa matenda oopsa ndi zizolowezi zoipa.
Muzochita zamankhwala, mankhwala angagwiritsidwe ntchito kuthetsa metabolic syndrome ndi hyperlipoproteinemia pokhapokha kuchuluka kwa lipoproteins kulimbikira ngati chithandizo cha matenda oyamba a pathological sichikugwira ntchito.
Tricor 145 imagwiritsidwa ntchito kukweza cholesterol ndi triglycerides kapena dyslipidemia wosakaniza bwino ndi mankhwala.
Contraindication
Mankhwala okhazikika motsutsana milandu:
- kwambiri galactosemia, lactase ndi kuchepa kwa fructose, galactose-glucose syndrome, sucrose-isomaltase malabsorption;
- kukhalapo kwa chidwi choonjezera pakuwala, kuzinthu zopanga Tricorra;
- chiwindi ndi kulephera kwa impso;
- Phototoxicity pa mankhwala ndi Ketoprofen, fibrate;
- kagayidwe kachakudya matenda mu ndulu;
- anaphylactic zochita za mtedza, soya ndi batala.
Ndi chisamaliro
Ndikofunikira kuwunika momwe wodwala alili pokhapokha pomayambitsa matenda omwe ali m'munsiwa:
- wofatsa kwa aimpso ndi kwa chiwindi kusakwanira;
- uchidakwa wambiri;
- ukalamba;
- mawonekedwe obadwa nawo a minofu matenda;
- kufanana mankhwala ndi anticoagulants yosalunjika ndi HMG-CoA reductase blockers.
M'pofunika kuyang'anira wodwala matenda ake akaperekedwa motsutsana ndi maziko a zakumwa zoledzeretsa.
Momwe mungatenge Tricor 145 mg
Mapiritsi ayenera kumwedwa pakamwa popanda kutafuna. Kuwonongeka kwa membrane wa filimu kungayambitse kuchepa kwa kusintha kwa fenofibrate kukhala fenofibric acid. Mankhwalawa amatha kumwa tsiku lonse, mosasamala chakudya. Odwala achikulire ayenera kumwa piritsi limodzi la 145 mg patsiku kamodzi.
Kutsitsa kwa lipid kumatha kugwira ntchito pakudya komwe kumapitilizidwa komanso muzochitika zolimbitsa thupi. Odwala omwe adathandizidwa ndi 160 mg ya mankhwalawa safuna kuchepetsedwa pang'onopang'ono kwa mlingo mpaka 145 mg.
Kumwa mankhwala a shuga
Mankhwalawa samakhudza kuchuluka kwa shuga m'magazi ndi zochitika za maselo a pancreatic beta. Chifukwa chake, odwala matenda a shuga a mellitus safunikira kusintha kwa mankhwala a insulin ndi hypoglycemic.
Zotsatira zoyipa
Zotsatira zoyipa za thupi zimawonekera chifukwa cha mlingo wosankhidwa bwino wa fenofibrate.
Matumbo
Matenda a dongosolo logaya chakudya amasonyezedwa ngati ululu mu epigastrium, kusanza, mapangidwe a mpweya ndi kutsegula m'mimba pang'ono. Pancreatitis ikhoza kuchitika.
Odwala omwe ali ndi matenda osokoneza bongo safunikira kuti asinthe mlingo wa insulin ndi mankhwala a hypoglycemic.
Hematopoietic ziwalo
Nthawi zina, mwa kuletsa kwazomwe zimayendera ndi ma mitsempha ya m'mimba, kuchepa kwa leukocyte komanso kukula kwa hemoglobin.
Pakati mantha dongosolo
Kusokonezeka kwamanjenje kumawonetsedwa mu mtundu wa kusokonekera kwa erectile, mutu.
Kuchokera musculoskeletal system ndi minofu yolumikizana
Mwachilendo komanso mwapadera, kukula kwa kupukusa myalgia, kukokana kwa minofu ndi ma spasms, kufooka, myositis, pachimake necrosis ya minofu minofu yamatumbo.
Kuchokera ku kupuma
Pali chiopsezo chochepa chokhala ndi pneumopathy ya interstitial.
Pa khungu ndi mafuta onunkhira
The kupezeka kwa thupi lawo siligwirizana khungu, yodziwika ndi mawonekedwe a zidzolo, urticaria, kuyabwa kwambiri. Nthawi zina, chidwi chakuwala chikuwonjezereka pakhungu, munthu amayamba kusiya tsitsi. Photosensitivity ikhoza kukhala limodzi ndi erythema, kupezeka kwa matuza.
Kuchokera ku genitourinary system
Kuchuluka kwa seramu creatinine ndi uric acid wambiri motsutsana ndi kumbuyo kwamikodzo.
Kuchokera pamtima
Matenda a mtima amadziwika ndi venous thromboembolism, kuphatikizapo pulmonary embolism ndi venous thrombosis m'munsi m'munsi.
Dongosolo la Endocrine
Mwina kutuluka thukuta kwambiri.
Pa mbali ya chiwindi ndi biliary thirakiti
Nthawi zambiri, ntchito zimawonjezeka ndipo kuchuluka kwa hepatic aminotransferase mu seramu yamagazi kumawonjezeka. Nthawi zina, cholelithiasis imayamba, mwina kutupa kwa chiwindi. Ngati zizindikiro za hepatitis zikuwonekera mu mawonekedwe a jaundice ndi kuyabwa, ndikulimbikitsidwa kuyezetsa mayeso labotale kuti mutsimikizire matendawa. Mukalandira zotsatira zabwino, kugwiritsa ntchito fenofibrate kutha.
Malangizo apadera
Musanayambe mankhwala osokoneza bongo, ndikofunikira kuti muchepetse zovuta zomwe zimayambitsa yachiwiri ya hypercholesterolemia, yomwe imatha kuchitika motsutsana ndi maziko a matenda a shuga 2, uchidakwa. Kugwiritsa ntchito bwino kwa mankhwalawa kumalimbikitsidwa kuti kuwunikidwe ndi ma laborator zizindikiro za kuchuluka kwamafuta a seramu. Popeza lipid-kutsitsa kanthu mkati mwa miyezi itatu, ndikofunikira kuti mufunsane ndi dokotala za kusintha kwa mankhwalawa.
Nthawi zina, motsutsana ndi maziko a mankhwalawa, kuyambika kwa njira yotupa mu kapamba ndikotheka.
Nthawi zina, motsutsana ndi maziko a mankhwalawa, kuyambika kwa njira yotupa mu kapamba ndikotheka. Zomwe zimayambitsa pancreatitis zimatha kukhala miyala komanso kupindika kwa ndulu,
Zokhudza mphamvu pakuwongolera njira
Mankhwala si doping kapena psychotropic, sizikuwawononga ntchito yapakati ndi zotumphukira mantha dongosolo. Chifukwa chake, mukamalandira chithandizo ndi Triicore, amaloledwa kuwongolera magwiridwe antchito ndi galimoto, yomwe imafunika kuthamangitsidwa ndikuwonetsetsa mwachangu.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Kutenga mankhwala ochepetsa lipid kumaletsedwa panthawi yomwe muli ndi pakati. Popereka mankhwala pakumwa yoyamwitsa, ndikofunikira kusamutsa mwana chakudya ndi zosakanikirana za mwana ndikuletsa kuyamwa.
Kupangira TRICOR 145 mg kwa ana
Oral hypolipidemic woletsedwa kuletsa mpaka zaka 18 chifukwa chosowa chidziwitso cha mphamvu ya fenofibroic acid pakukweza kwa thupi la munthu pasukulu yaukalamba komanso unyamata.
Gwiritsani ntchito mu ukalamba
Anthu azaka zosaposa zaka 70 ayenera kuwunika bwino momwe alili ndi mankhwala a fenofibrate.
The ntchito aimpso kuwonongeka
Mankhwala ndi contraindicated mu kwambiri aimpso kulephera.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Mankhwalawa amaletsedwa kugwiritsidwa ntchito ndi anthu omwe ali ndi matenda oopsa a chiwindi.
Bongo
Wothandizira wotsutsa alibe. Izi ndichifukwa chakusowa kwa milandu yambiri. Pogwiritsa ntchito mapiritsi amodzi kamodzi, pali njira zambiri zowonjezera zovuta zowonjezera zomwe zimachitika. Ngati mukukayikira kuti pali mankhwala osokoneza bongo, muyenera kupita kuchipatala. Mankhwalawa sachotsedwa ndi hemodialysis.
Ndi zoletsedwa kumwa mowa panthawi yamankhwala ndi Tricor.
Kuchita ndi mankhwala ena
Fenofibrate ndi zinthu zake zama metabolic sizoletsa cytochrome P450 isoforms.
Kuyenderana ndi mowa
Ndi zoletsedwa kumwa mowa panthawi yamankhwala ndi Tricor. Mowa wa Ethyl umatha kufooketsa lipid-kutsitsa, umayambitsa chopinga cha hepatobiliary ndi mantha.
Kuphatikiza kophatikizidwa
Fenofibroic acid imawonjezera mphamvu yothandizira ya anticoagulants pakamwa. Chifukwa cha kuphatikiza uku, kutulutsa magazi mkati. Zotsatira zoyipa zimakhala chifukwa chotulutsidwa kwa anticoagulant kuchokera kumalo omanga mapuloteni a plasma.
Kumayambiriro kwa mankhwala osokoneza bongo ndi fenofibrate, tikulimbikitsidwa kukaonana ndi dokotala zakufunika kochepetsera Mlingo wa anticoagulants wa tsiku ndi tsiku. Kusankha kwa mtundu wotsatira kumachitika molingana ndi chikhalidwe cha INR.
Pogwiritsa ntchito mapiritsi amodzi kamodzi, pali njira zambiri zowonjezera zovuta zowonjezera zomwe zimachitika.
Osavomerezeka kuphatikiza
Chifukwa cha chiwopsezo chachikulu cha minyewa, zotsatira za fenofibrate ndi HMG-CoA reductase blockers ndi zotumphukira za fibrate sizivomerezeka.
Kuphatikiza komwe kumafunikira kusamala
Ndikulimbikitsidwa kuti nthawi zonse muziyang'anira magwiridwe antchito pomwe a Tricor ali ndi cyclosporine kapena maantibayotiki. Akaphatikizidwa, pamakhala chiwopsezo cha kulephera kwambiri kwa impso. Ndikusintha kwamphamvu magawo a labotale, muyenera kusiya kutenga Tricor.
Analogi
Mankhwalawa akhoza kutha ndi amodzi mwanjira zotsatirazi:
- Lipantyl;
- Fenofibrate Canon;
- Gofibrat;
- Zopepuka.
Zotsatira za holide za Treicor 145 mg kuchokera kuma pharmacies
Mapiritsi amapezeka kokha pamalangizo azachipatala mwachindunji.
Kodi ndingagule popanda kulandira mankhwala?
Mankhwalawo sagulitsidwa popanda mankhwala a dokotala chifukwa choopsa kwambiri cha zotsatira zoyipa ngati atagwiritsidwa ntchito molakwika.
Mtengo
Mtengo wapakati wamapiritsi ndi ma ruble 931.
Zosungidwa zamankhwala
Ndikofunikira kukhala ndi mankhwalawa pamalo ochepetsetsa ocheperako kutali ndi ma ray a ultraviolet pamatenthedwe mpaka + 25 ° C.
Tsiku lotha ntchito
Zaka zitatu
Wopanga Tricor 145 mg
Reciphon Fontaine, France.
Mankhwala akhoza m'malo ndi analog Fenofibrat Canon.
Ndemanga za Tricor 145 mg
Pamabwalo opezeka pa intaneti, madokotala ndi odwala amasiya ndemanga zabwino zambiri. Ndemanga zoyipa zimawonekera chifukwa cha kuwoneka kwa zoyipa.
Madokotala
Romanov Denis, endocrinologist, St.
Ichi ndi mankhwala ochepetsa lipid, koma Tricor amachepetsa ma triglycerides kwakukulu. Ndikupangira kugwiritsa ntchito mtundu wa dyslipidemia wamitundu IIa, IIb, III ndi IV. Mlingo ndi nthawi ya chithandizo amakhazikitsidwa payekhapayekha. Ndikukuchenjezani kuti pochita, mankhwalawa ali ndi vuto lotsitsa cholesterol. Mapiritsi amatsutsana ndi anthu omwe ali ndi vuto la chiwindi.
Odwala
Gennady Likhachev, wazaka 38, Yekaterinburg
Ndimasiya ndemanga zoyipa za Tricor. Dokotala adalemba mankhwalawo ngati m'malo mwa Torvacard, chifukwa panali HDL yotsika. Pambuyo pa miyezi 4-5 ndikuvomera, ndidawona mawonekedwe akununkhira, kusanza, komanso kusanza. Pa 8-9 miyezi othandizira ochizira poyerekeza ndi kutuluka kwa magazi ndi mawonekedwe a colic mu ndulu, ntchito idakonzedwa. Kuyang'ananso ndulu kunawonetsa viscous bile ndi miyala yambiri. Pambuyo pa opareshoni, kuukira kunatha.
Roman Sorokin, wazaka 53, Stavropol
Ndili ndi matenda a shuga a retinopathy, omwe amachitidwa opaleshoni yamaso ndi opaleshoni m'maso anga kangapo. Kuti muchepetse kuchira, ndikuvomereza Tricor, yemwe amathana ndi ntchito yake. Pankhaniyi, mankhwalawa amachepetsa kuyika mafuta m'thupi m'magazi kuti azikhala bwino. Ndimamwa mankhwalawa pafupipafupi kwa miyezi 10, ndikutsatira kupuma kwa miyezi iwiri. Sindinazindikire zotsatira zoyipa komanso kugunda kwamankhwala panthawi yonse yodya.
