Maantibayotiki a Fluoroquinolone amagwiritsidwa ntchito pochizira ndi prophylactic mu matenda omwe ali ndi matenda opatsirana. Mankhwalawa amaphatikizapo ciprinol. Kuphatikizika kwa chinthu chachikulu pakuphatikizidwa kwa mankhwalawa kumasiyana malinga ndi mawonekedwe omwe amasulidwa. Mankhwala omwe mumalandira mumagwiritsidwa ntchito molingana ndi mtundu womwe umasankhidwa, womwe umachepetsa chiopsezo chokhala ndi zizindikiro za bongo.
Dzinalo Losayenerana
Ciprofloxacin.
Maantibayotiki a Fluoroquinolone amagwiritsidwa ntchito pochizira ndi prophylactic mu matenda omwe ali ndi matenda opatsirana. Mankhwalawa amaphatikizapo ciprinol.
ATX
J01MA02.
Nambala yomwe yawonetsedwa satifiketi yolembetsa - LS-000047 - P N014323 / 01. Tsiku lolembetsa - 07.22.08.
Kutulutsa mafomu ndi kapangidwe kake
M'masamba, mitundu ingapo ya kutulutsidwa kwa mankhwala antimicrobial imakwaniritsidwa. Awa ndi mapiritsi, onjezerera ndi jakisoni. Mitundu yonse ya mulingo umakhala wolumikizidwa chifukwa zimakhala ndi ciprofloxacin monohydrate hydrochloride - chinthu chachikulu. Ciprinol 500 imapezeka mu mawonekedwe a piritsi yokha, zomwe zimapangidwa ndi 500 mg.
Kutsatira ndi kutsata kumafunikira makina ophatikizira. The moyikirapo amagwiritsidwanso ntchito ngati kutsitsi pochiza ma postoperative sutures ndi madontho amaso. Madzimadzi (m'mitundu yonse iwiri) ndiwowonekera komanso opanda khungu. Pocheperapo, yankho limakhala lobiriwira chikasu (kutengera wopanga).
Zomwe zimagwira piritsi la piritsi ndi 250 mg, 500 mg ndi 750 mg. Kusunthika kumatsimikiziridwa ndi wopanga. Zinthu zothandiza ndi okhazikika zomwe zimachulukitsa bioavailability ya chinthu chachikulu ndikuthandizira kuthira. Piritsi lililonse ndi filimu. Mndandanda wazinthu zowonjezera:
- sodium carboxymethyl mapadi;
- silika;
- primellose;
- stearic acid;
- MCC;
- polyvinylpyrrolidone.
Chigoba chili ndi:
- hydroxypropyl methylcellulose;
- titanium dioxide;
- zakumwa za m'mimba;
- talcum ufa.
Ma meshes okhala ndi mapiritsi 10 ozungulira biconvex. Iliyonse imakhala ndi notch (mbali imodzi). Mu bokosi la makatoni - zosaposa 1 mesh phukusi. Malangizo ogwiritsira ntchito adatsekedwa.
Zotsatira za pharmacological
The yogwira pophika mtundu uliwonse Mlingo ali kutchulidwa antibacterial katundu. Maantibayotiki ndi a gulu la fluoroquinolones a m'badwo wachiwiri. Kusankha topoisomerase inhibitor, kumakhudza DNA ya tizilombo toyambitsa matenda. Amalepheretsa mapuloteni amtundu wa bacteria.
Kuzindikira kwa tizilombo tating'onoting'ono kumachitika chifukwa cha bacteriostatic effect. Mankhwalawa amagwiritsidwa ntchito ngati gawo la mankhwala a mono-ndi zovuta m'malo ambiri amankhwala. Kuthamanga kwakukulu motsutsana ndi maorganic tizilombo a anaerobic kulibe.
Mabakiteriya omwe ali ndi grram zabwino ku ciprofloxacin:
- Neisseria gonorrhoeae;
- Pseudomonas aeruginosa;
- Neisseria meningitidis;
- Escherichia coli;
- Salmonella spp;
- Shigella spp.
Mabakiteriya osagwirizana ndi mankhwalawa:
- Enterococcus spp;
- Legionella spp;
- Staphylococcus spp;
- Chlamydia spp;
- Campylobacter spp;
- Mycobacterium spp;
- Mycoplasma spp.
The yogwira pophika mtundu uliwonse Mlingo ali kutchulidwa antibacterial katundu.
Tizilombo toyambitsa matenda a Anaerobic omwe kukana kwake kwatsimikiziridwa:
- Clostridium Hardile;
- Nocardia asteroides;
- Ureaplasma urealyticum.
Tizilombo tating'onoting'ono ta Beta-lactamase timakhala tomwe timagwiritsa ntchito mankhwalawa.
Pharmacokinetics
Njira yolekerera piritsi imachitika m'matumbo. Zakudya zomwe zimatengedwa kale sizimakhudza mayamwidwe ndi bioavailability mwanjira iliyonse (zosaposa 75% za fomu ya piritsi). Kuphatikizika kwakukulu kwa chinthu chachikulu kumatha kutsimikizika pambuyo pa mphindi 90-120 pambuyo pa kumwa koyamba. Chidacho chimafalikira ndi magazi ndipo chimagawilidwa mofananamo pa minofu yonse yofewa, minyewa ndi kupuma.
Ndi kulowetsedwa kwa mtsempha, kuchuluka kwa mayamwidwe kumakhalabe kosasinthika. Biotransformation imachitika m'chiwindi. Ma metabolabol satha ntchito.
Ngati wodwala alibe zotsutsana kuchokera kumbali ya impso ndi kwamikodzo, kuchotsedwa kwa mankhwalawa (pamodzi ndi mkodzo) kumatenga maola 3-6. Pozindikira kulephera kwa aimpso ndi ma pathologies ena, nthawi yochotsedwa imangowonjezereka mpaka maola 10-12. Mimbulu sinatulutsidwe.
Imalowa mkatikati mwa chotchinga ndi mkaka wa m'mawere.
Kodi chimathandiza ndi chiyani?
Kugwiritsa ntchito maantibayotiki a gulu la fluoroquinolone pazithandizo zothandizira kumachitika pozindikira wodwala yemwe ali ndi matenda a etiology omwe akudwala matenda opatsirana. Zizindikiro zotsatirazi zikuwonetsedwa muzowonjezera:
- matenda a pakhungu (zilonda zam'mimba, zilonda zam'mimba, kuwotcha, sutures yomwe idatengedwa pambuyo pa opaleshoni)
- matenda opatsirana amuna ndi akazi a m'chiuno (prostatitis, chlamydia, salpingitis);
- matenda kupuma thirakiti (chibayo, bronchitis);
- Matenda a ENT (tonsillitis, sinusitis, otitis media);
- matenda amkodzo thirakiti (urethritis, pyelonephritis, cystitis);
- matenda am`mimba thirakiti (matumbo, cholangitis);
- matenda a minofu mafupa ndi mafupa (nyamakazi, osteomyelitis);
- monga prophylaxis yokhudzana ndi matenda opatsirana komanso otupa mthupi pambuyo pakuchita opaleshoni.
Kumwa mapiritsi a antibayotiki a Ciprinol 500 kumakhala kosatheka munthawi yomaliza ya mimba.
Contraindication
Kumwa mapiritsi olimbana ndi mankhwalawa kumakhala kosatheka ngati wodwala ali ndi zotsutsana kwathunthu. Izi zikuphatikiza:
- otsala atatu omaliza a mimba (2-3);
- tsankho ku chigawo chachikulu;
- Kugwiritsa ntchito tizanidine ndi ciprofloxacin;
- zaka za ana (mpaka zaka 18).
Kupatula komwe kumatha kukhala zovuta kwa ana azaka 6 mpaka 17 ndipo zimayambitsidwa ndi Pseudomonas aeruginosa.
Ndi chisamaliro
Kuphatikizidwa kwa mankhwala popanga mankhwala kuyenera kusamala poyerekeza ndi odwala omwe ali ndi zotsatirazi:
- cerebrovascular atherosulinosis;
- khunyu
- matenda amisala;
- kwambiri aimpso ndi kwa chiwindi kuwonongeka.
Kuphwanya kwa magazi m'magazi mu ubongo kumaonedwa kuti ndi cholakwika pakugwiritsa ntchito mankhwalawa.
Kodi kutenga Ciprinol 500?
Mlingo wa mankhwalawa amatengedwa pakamwa katatu patsiku. Muyezo watsiku ndi tsiku la gawo lalikulu suyenera kupitilira 1500 mg. Mapiritsi ayenera kuledzera maola 6 aliwonse, mosasamala kanthu za kudya. Nthawi ya chithandizo yatha mpaka masiku 14. Maphunzirowa ndi muyezo wowonjezera mutha kuwonjezereka ndi chilolezo chodwala.
Intravenous makonzedwe akhoza kukhala ndege ndi dontho. Zotsirizazo ndizokonda. Mlingo wa jakisoni imodzi ndi 200 mg, ndi zotupa - zosaposa 400 mg. Kuganizira mozama ndi yankho, mukapatsidwa dropwise, zimaphatikizidwa ndi kulowetsedwa (dextrose, fructose) mpaka voliyumu yofunikira.
Ndi matenda ashuga
Matenda a shuga amafunika kuvomerezedwa mosamala. Kuwongolera kwa Mlingo wa mankhwalawa kumachitika potsatira kuchepa kwake. Kuyang'anira kuchipatala ndikofunikira.
Zotsatira zoyipa
Matenda aliwonse omwe amapezeka nthawi yothana ndi ma antibayotiki amakhala okhudzana ndi mavuto. Amawonekera pamtunda wam'mimba, chapakati chamanjenje, ziwalo zam'maganizo, urogenital ndi minofu yam'mimba.
Matenda aliwonse omwe amapezeka nthawi yothana ndi ma antibayotiki amakhala okhudzana ndi mavuto.
Matumbo
Dyspepsia, anorexia, pseudomembranous colitis, mavuto azakudya, kuchepa kwa chilakolako chokwanira, hepatonecrosis yokhudzana ndi zotsatira zoyipa.
Hematopoietic ziwalo
Hematopoietic ziwalo secrete anemia, thrombocytopenia, leukopenia, leukocytosis, thrombocytosis.
Pakati mantha dongosolo
Zotsatira zoyipa za mankhwalawa pakhungu lamkati zimawonekera mwa kugwidwa, kupweteka mutu, chizungulire, kukhumudwa, kukomoka, nkhawa, komanso kuyerekezera zinthu.
Kuchokera kwamikodzo
Kuchokera kwamkodzo dongosolo, crystalluria, polyuria, hematuria, kutulutsa magazi mkati (kawirikawiri) kumawonedwa.
Kuchokera ku ziwalo zamagetsi
Pali kuphwanya kununkhira, khungu la kanthawi pang'ono ndi ugonthi, tinnitus pang'ono.
Zotsatira zoyipa za mankhwala a Ciprinol 500 pakatikati kwamanjenje zimawonetsedwa mwa kugwidwa.
Pa khungu
Zingwe zimawoneka pakhungu, limodzi ndi kuyabwa ndi kuyaka. Mapapu amatha kupanga. Zipatso zimapezeka pamalo opangira timitseko ting'onoting'ono ta magazi.
Kuchokera ku minculoskeletal system
Kuchokera ku minculoskeletal system nyamakazi, myalgia, kutupa ndi arthralgia. Chiwopsezo cha kuphulika kwa tendon chikuwonjezeka.
Kuchokera pamtima
Zotsatira zoyipa za mankhwalawa pamtima zimasonyezedwa pakuwonjezeka kwa kugunda kwa mtima, kutsitsa magazi ndi tachycardia.
Matupi omaliza
Thupi lawo siligwirizana pa mankhwala akufotokozedwa mu mawonekedwe a urticaria, mapangidwe a matuza, exanthema. Kutuluka thukuta kwambiri ndi kufooka wamba kumawonekera mu 12% ya odwala.
Malangizo apadera
Ngati odwala ali ndi contraindication wachibale (khunyu, matenda a cerebrovascular), mankhwala ochepetsa mphamvu ya mankhwalawa amatchulidwa kokha pazifukwa zaumoyo. Ngati kutsegula m'mimba kumayenderana ndi mankhwalawa panthawi yonse ya makonzedwe, ndiye kuti muyenera kupimidwa kuti mufufuze matenda am'mimba. Mukatsimikizira matenda, ndikofunikira kusiya kugwiritsa ntchito mankhwalawa posachedwa.
Kuchita zolimbitsa thupi kwambiri kuyenera kuthetsedwa. Kukhala padzuwa nthawi yayitali ndikosavomerezeka. Kuwonjezeka kodziimira patsiku la tsiku ndi tsiku kumawonjezera chiopsezo cha crystalluria.
Kuyenderana ndi mowa
Mankhwala samayenderana ndi mowa. Ethanol osakanikirana ndi ciprofloxacin amakwiya ndi kuledzera.
Zokhudza mphamvu pakuwongolera njira
Chifukwa cha kusowa tulo, akatswiri amalola kuyendetsa mosamala ndi magalimoto ena.
Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere
Sikulimbikitsidwa kuphatikiza mankhwala a antibacterial pochiza. Amagwiritsidwa ntchito pazochitika zapadera komanso pazifukwa zaumoyo.
Kulemba za Ciprinol kwa ana 500
Kufikira zaka 18 sanasankhidwe. Chosiyana ndi anthrax ndi pulmonary cystic fibrosis, omwe adapezeka ndi ana a zaka 5 mpaka 17.
Gwiritsani ntchito mu ukalamba
Okalamba odwala ayenera kuyamba ndi theka. Kulandila kumachitika motsogozedwa ndi katswiri.
The ntchito aimpso kuwonongeka
Kulandila mosamala moyang'aniridwa ndi katswiri.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Kutsutsana. Chisamaliro chiyenera kutengedwa.
Bongo
Zizindikiro za bongo zimawonetsedwa ngati kusanza, kukomoka, kupweteka mutu, kusokonezeka, kupweteka pachifuwa ndi m'mimba, kuyerekezera zinthu. Chithandizo chotsimikiziridwa ndi dokotala. Gastric lavage ndi makonzedwe a enterosorbent amafunikira.
Zizindikiro za mankhwala osokoneza bongo a Ciprinol 500 amawonetsedwa ngati kusanza.
Kuchita ndi mankhwala ena
Didazonin amachepetsa mayamwidwe a antibayotiki. Theophyllines ndi xatins amatuluka pang'onopang'ono kuchokera mthupi pamene akumamwa mankhwala othandizira. Index ya thrombopropin ikhoza kuchepa ndi kugwiritsa ntchito mankhwalawa limodzi ndi mankhwala a hypoglycemic. Chiwopsezo cha kudwala malungo ndi kugwidwa chimawonjezeka pogwiritsa ntchito nthawi yomweyo mankhwala osapweteka a antiidal ndi antiotic.
Mankhwala omwe amachepetsa uric acid wambiri komanso amathandizira kuti athetse mwachangu amatha kukulitsa nthawi yochulukitsa ya profrofloxacin kuchokera mthupi. The pakati pakati kumwa maantiacid ndi mankhwala ndi 4-5 maola.
Analogi
Mankhwala okhudzana ndi fluoroquinolones ali ndi maupikisano angapo omwe amofanana ndi achire. Izi zikuphatikiza:
- Syphlox. Fomu la piritsi ili ndi 250-500 mg ya ciprofloxacin. Mtengo - kuchokera ku ma ruble 150.
- Choonadi. Generic, yomwe imakhala ndi hemifloxacin mesylate (160-320 mg). Mtengo - kuchokera ku ma ruble 950.
- Lefoktsin. Kutulutsa mawonekedwe - mapiritsi. Levofloxacin hemihydrate (250-500 mg). Mtengo - kuchokera ku ma ruble 300.
Kudzisankhira wogwirizira sikumaperekedwa.
Maholide a Zipronol 500 ochokera ku malo ogulitsa mankhwala
Tchuthi chotsatsa.
Kodi ndingagule popanda kulandira mankhwala?
Simungagule mankhwala popanda mankhwala.
Mtengo
Mtengo wa piritsi pamafakitala umachokera ku ma ruble 63.
Simungagule mankhwala popanda mankhwala.
Zosungidwa zamankhwala
Pewani kutali ndi zinyama, ana, moto, kuwala kwa dzuwa ndi chinyezi.
Tsiku lotha ntchito
Osapitirira zaka 5.
Wopanga Cipronol 500
Slovenia, nkhawa KRKA.
Umboni wa madotolo ndi odwala za Ciprinol 500
Samokhvalov Arkady, dermatologist, Krasnodar
Kuchepa kwa matendawo chifukwa chogwiritsa ntchito maantibayotiki ndizochepa, nthawi zambiri ndimapereka mankhwala kwa odwala. Chifukwa cha kukhudzana kwambiri kwa mankhwalawa, njira yochizira imawonedwa pakatha masabata 1 mpaka 5 pambuyo pa kugwiritsa ntchito koyamba. Kugwiritsa ntchito polimbana ndi matenda a pakhungu ndi minofu yofewa.
Oksana Sapozhnikova, wazaka 36, Samara
Zaka 2 zomaliza zomwe zimavutitsidwa ndi bronchitis. Mu shuga mellitus, othandizira onse antimicrobial ayenera kumwedwa mosamala, motero kutenga mankhwala a fluoroquinolone adayamba ndi theka. Thandizo linabwera patatha masiku awiri, kupendekera kunasowa. Kuyamwa pang'ono kunawonedwa, kuyimitsidwa kunachotsedwa ndi mafuta a antihistamine ndi mpweya wozizira. Ndine wokhutira ndi zotsatira zake.
