Cyprolet 250 mg ndi mankhwala ochepetsa mphamvu ya antibacterial omwe ali ndi zotsutsana zosiyanasiyana. Amagwiritsidwa ntchito pochiza matenda opatsirana ambiri. Mankhwalawa amatha kuperekedwa kwa odwala omwe ali ndi chitetezo chokwanira.
ATX
Mankhwalawa amaphatikizidwa ndi gulu la mankhwala a quinolone a m'badwo wachiwiri. Malinga ndi gulu la ATX, ili ndi code J01MA02.
Cyprolet 250 mg ndi mankhwala othandiza kwambiri antibacterial.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwala amagulitsidwa mwanjira zotsatirazi:
- mafilimu okhala ndi mafilimu a 250 kapena 500 mg;
- yankho la mtsempha wa magazi makonzedwe a 2 mg / ml;
- ophthalmic akutsikira 3 mg / ml.
Cyprolet mu mawonekedwe a jakisoni, kuyimitsidwa, mafuta opaka sichinachitike.
Mapiritsiwo ndi ozungulira, a biconvex, okhala ndi chipolopolo choyera, achikasu kumapeto. Ciprofloxacin hydrochloride adayambitsidwa ndikuyambitsa ngati chinthu yogwira ntchito. Kudzazidwa kothandizila kumaphatikizapo microcrystalline cellulose, anhydrous colloidal silicon diabetes, starch, croscarmellose sodium, stearate ndi magnesium hydrosilicate. Kuphimba kwa enteric kumakhala ndi talc, polyethylene glycol, hypromellose, dimethicone, polysorbate 80, titanium dioxide (E171), ndi sorbic acid.
Mapiritsi 10 adamangidwa. m'matumba otupa. Chithuza chimodzi chimayikidwa m'mathumba okhala ndi makatoni ndi malangizo ogwiritsira ntchito.
Mitundu ina ya mankhwalawa yokwanira 250 mg mulibe.
Ciprofloxacin ndi chinthu chogwira ntchito cha Ciprolet 250.
Zotsatira za pharmacological
Mankhwala amawonetsa bactericidal katundu. Monga yogwira mankhwala, ciprofloxacin imagwiritsidwa ntchito - mankhwala osiyanasiyana a fluoroquinolone antiotic. Mu cell ya bakiteriya, imagwira ntchito ngati choletsa ma enzymes a topoisomerase, momwe maupangiri wa DNA umadalira. Chifukwa cha zomwe anachita:
- mapuloteni biosynthesis ndi opuwala;
- Kubwereza kwa DNA ndikutchinga;
- kusintha kwa nembanemba;
- chigamba chakunja chikuwonongeka;
- kukula kwa khungu kumayima;
- kubereka kwa bakiteriya kumakhala kosatheka;
- tizilombo tofa.
Kufalitsa mwachangu ndi mabakiteriya ocheperako amakhudzidwa ndi mankhwalawa. Palibe mitundu yosagwiritsiridwa ntchito mosiyanasiyana mankhwala, chifukwa chake kukana maantibayotiki kumatuluka pang'onopang'ono.
Cyprolet imakhala yothandiza polimbana ndi ma aerobes ambiri.
Ciprofloxacin imagwira bwino ntchito kuthana ndi ma aerobes ambiri, gramu-gramu, gram-negative, intracellular, β-lactamase yopanga tizilombo toyambitsa matenda:
- staphylococci;
- zovuta zina za streptococci;
- fuluwenza;
- Mapuloteni
- ma vibrioes;
- legionella;
- Klebsiella;
- enterobacteria;
- nsomba;
- Escherichia coli;
- Server;
- cytobacteria;
- brucella;
- Pseudomonas aeruginosa;
- Shigella
- chlamydia.
Mankhwala oletsa matenda oopsa amakhudza anaerobes, sangathe kupirira ndi Stenotrophomonas maltophilia, Bacteroides fragilis, Burkholderia cepacia, treponema, myco- ndi ureaplasma, pneumococcus, bacteroids, tizilombo toyambitsa matenda a pseudomembranous colitis ndi nocardiosis. Popita nthawi komanso kutengera malo, chidwi cha tizilombo toyambitsa matenda chimatha kusintha.
Ndi atitis media, Cyprolet 250 mg imasonyezedwa.
Pharmacokinetics
Kuchokera pamimba yodyera, mankhwalawa amadziwitsidwa mu maola 1-2. Zomwe zili ndi plasma za ciprofloxacin pa mlingo wa 250 mg ndi 1.2 μg / ml. Bioavailability pafupifupi 75%. Kudya kumachepetsa kuthamangitsidwa kwa matumbo ochepa, koma sizikhudzanso zina. Ikagwiritsidwa ntchito kwambiri ku gawo la masomphenyawo (madontho), kulowetsa ofooka m'magazi kumawonedwa.
Maantibayotiki amagawidwa mthupi. Imadutsa chotchinga, chomwe chimapukusidwa mkaka wa m'mawere, chimatsimikiziridwa mu madzi amkati ngakhale pakalibe kutupa kwawoko. Zomwe zimakhala mu minofu ndizokwera kwambiri kuposa kuchuluka kwa plasma. Mothandizidwa ndi kuchuluka kwamankhwala, amalowa m'mapapu, matenda ammatumbo, mavu, chiwindi, bile, minofu ndi mafupa, ziwongo, ziwalo, ma cell, ma cell.
Kupanga ma metabolic sikupitirira 30%, kochitidwa ndi chiwindi. Zinthu zonse zowola zimagwira, koma lowetsani magazi m'magawo otsika. Kuyeretsa thupi kumatenga maola 6-12. Ma metabolabolites ndi ciprofloxacin osasinthika amachotsedwa mkodzo. Pang'ono pang'ono amathamangitsidwa ndi ndowe. Ndi matenda a impso, theka la moyo ndi maola 12. Zaka sizikhudza pharmacokinetics.
Zomwe zimathandiza
Wothandizila mankhwala omwe amafunsidwa amagwiritsidwa ntchito kuti athetse matenda a bakiteriya, kuphatikizapo osadziwika. Zisonyezero zogwiritsidwa ntchito:
- Matenda a ENT - otitis media, mastoiditis, sinusitis, tonsillitis, pharyngitis, nasopharyngitis, tonsillitis.
- Zotupa zamadzimadzi zotupa - bronchitis (pachimake ndi matenda obwera chifukwa cha kupuma), mapapo ndi mapokoso, kuchuluka, chibayo, kupatula streptococcus pneumoniae.
- Matenda am'mimba thirakiti - campylobacteriosis, kolera, salmonellosis, shigellosis, typhoid, enteritis, colitis.
- The matenda a impso ndi kwamikodzo ducts - cystitis, nephritis, urethral syndrome.
- Matenda amtundu - oophoritis, kutupa kwa prostate, endometritis, adnexitis, chancre, zotupa za chlamydial, gonorrhea.
- Peritonitis
- Anthrax (matenda a m'mapapo).
- Septicemia.
- Kuwonongeka kwa mafupa, mafupa awo, khungu ndi minyewa yodutsa - osteomyelitis, carbuncle, furuncle, phlegmon, abscess, matenda a zilonda zam'mimba, mafupa am'mimba, bursitis.
Ciprolet ingagwiritsidwe ntchito ngati gawo la zovuta antibacterial mankhwala. Nthawi zina amagwiritsidwa ntchito pofuna kupewa - ndi opareshoni, odwala omwe ali ndi neutropenia, odwala omwe amamwa mankhwala a immunosuppressive, kuphatikiza popewa kukula kwa anthrax ndi meningitis.
Cyprolet 250 sinafotokozedwe pa nthawi yapakati.
Contraindication
Mankhwala sinafotokozedwe ngati:
- tsankho kuti zikuchokera;
- mbiri ya ziwengo kwa fluoroquinolones;
- kudziwika kwa pseudomembranous colitis;
- mimba
- yoyamwitsa.
Amapatsirana odwala osakwana zaka 18. Kugwiritsa ntchito maantibayotiki mu ana kungovomerezeka kwa ana omwe ali ndi zovuta za cystic fibrosis kapena, ngati pakufunika, chithandizo / prophylaxis cha anthrax ya pulmonary. Apa gawo la m'badwo limachepera kukhala zaka 5.
Ndi chisamaliro
Chenjezo liyenera kuchitika mosalephera aimpso kulephera, kuwonda kwa myasthenia gravis, kuwonongeka kwa chiwindi, kusokonekera kwa magazi kuubongo, kuthekera kwa kugwidwa, matenda amisala, komanso popereka mankhwala kwa odwala okalamba.
Ciprolet 250 imayikidwa mosamala kuti chiwindi chiwonongeke.
Momwe mungatenge Ziprolet 250
Mankhwala amatchulidwa ndi dokotala. Mapiritsiwa amakhala ndi zokumbira zomwe zimateteza mucous m'mimba ku zotsatira zoyipa za mankhwalawa, chifukwa chake sayenera kuphwanyidwa kapena kutafunidwa. Mankhwala amkamwa amaphatikizidwa ndimadzi ambiri. Cyprolet sichimagwirizana ndi zinthu zamkaka. Kudya chakudya kumalepheretsa mayamwidwe okonzekera. Pankhaniyi, mapiritsi amalimbikitsidwa kuti amwe pamimba yopanda kanthu kapena maola awiri chakudya chikatha.
Mlingo watsimikiza ndi dokotala, poganizira zovuta zosiyanasiyana. Nthawi yolimbikitsidwa pakati pa Mlingo ndi maola 12. Ndi kupatuka kwakukulu mu ntchito ya impso, milingo yocheperako imayikidwa, pafupipafupi kuvomerezedwa kumachepetsedwa 1 nthawi patsiku. Nthawi zina njira ya mankhwala kwa odwala akuluakulu imayamba ndikuyambitsidwa kwa kulowetsedwa kwa ciprofloxacin.
Kenako wodwalayo amwe mankhwalawo pakamwa.
Madzi a kulowetsedwa amagwirizana ndi mayankho:
- sodium kolorayidi 0,9%;
- dextrose 5% ndi 10%;
- fructose 10%;
- Ringer's.
Mapiritsi a 250 mg angagwiritsidwe ntchito pochiza ana kuyambira zaka 5 kuti athane ndi Pseudomonas aeruginosa ndi Bacillus anthracis (moyang'aniridwa ndi achipatala okhwima).
Cyprolet 250 imatha kuthandizidwa pamaso pa anthu odwala matenda ashuga.
Njira yamankhwala ingasiyane. Nthawi zambiri zimakhala masiku 5-7, koma nthawi zina zimatenga milungu ingapo kapena miyezi ingapo kuti athetse matendawa. Tizilombo tina toyambitsa matenda tili ndi vuto lochepetsedwa ndi zochita za mankhwalawa, choncho, mankhwala ena owonjezera a antibayotiki amatchulidwa, mwachitsanzo, ndi matenda a streptococcal - beta-lactams.
Kodi ndizotheka kumwa mankhwalawa chifukwa cha matenda ashuga
Mankhwala omwe akufunsidwa akhoza kumwedwa pamaso pa matenda ashuga. Komabe, ziyenera kukumbukiridwa kuti zimatha kuyambitsa chitukuko cha hypo- kapena hyperglycemia.
Kuyang'anira shuga wamagazi ndikofunikira.
Zotsatira zoyipa
Mankhwala amatha kuyambitsa mavuto osiyanasiyana. Amawoneka pafupipafupi, zotsatira zoyipa zimachitika kamodzi.
Matumbo
Kuchepa kwa chakudya kapena kusapezeka, kutsegula m'mimba, kusanza komanso kusanza, kupweteka m'mimba, kuwonongeka m'matumbo, kuchuluka kwa michere ya chiwindi, hepatitis, jaundice chifukwa cha cholestasis, hepatonecrosis.
Kuchepetsa mseru komanso kupsinjika ndi zotsatira zoyipa za Ciprolet 250.
Hematopoietic ziwalo
Kupsinjika kwa m'mafupa, kusintha kwa kapangidwe ka magazi mpaka pancytopenia.
Pakati mantha dongosolo
Vertigo, migraine, kuchepa mphamvu, kupsinjika, kuda nkhawa, kusokonezeka kwa zochitika zama psychomotor, masomphenya, kusowa tulo, zolota, kupweteka kwa m'mimba, kuwonongeka pang'ono, kumva kupweteka, kunjenjemera, kupweteka minofu ndi mafupa, zowona, zamkati, zonyansa komanso zolakwika.
Kuchokera kwamikodzo
Kuchepa kwamkodzo mkodzo, mawonekedwe amtundu wamagazi ndimakristali amchere mkati mwake, komanso kuwonongeka kwa impso.
Kuchokera pamtima
Kukhathamira kwa magazi kumutu, kumva kutentha, kusokonezeka kwa mtima, kuchepa kwa magazi, kuchepa kwa magazi kwa magazi, kuchepa kwa nthawi ya QT pa ECG, kuchuluka kwa bilirubin, urea, ndi shuga m'magazi.
Mankhwalawa ndi Ciprolet 250, kumwa mowa kumapangidwa.
Matupi omaliza
Kuyabwa, hyperemia, zidzolo, kutupa, kutentha thupi, kubisalira, Stevens-Johnson, bronchospasm, anaphylactoid reaction.
Malangizo apadera
Pambuyo pochotsa zisonyezo za matendawa, mapiritsi amayenera kuledzera kwa masiku ena awiri.
Chifukwa chotenga mankhwalawa, pseudomembranous colitis imatha kukhala, ikufunika chithandizo chamankhwala mwachangu. Matenda ophatikizana ndi antibiotic sangathetsedwe ndikupondereza matumbo.
Ngati zizindikiro za kuwonongeka kwa hepatobiliary system (kupweteka kwam'mimba, jaundice, mkodzo wakuda, kuyabwa) zayipa, muyenera kusiya kumwa Ciprolet ndi kupita kuchipatala.
Pali chiopsezo cha tendinopathy, kupasuka kwa tendon ndikotheka. Kukondwerera kumayamba.
Ndi chizolowezi chofuna kupsinjika, khunyu, kuwonongeka kwa ubongo, ubongo wamatumbo, kuvulala pachiwopsezo ndipo mutatha kupweteka, antibacterial mankhwala amagwiritsidwa ntchito mosamala.
Adalola kuikidwa kwa Cyprolet 250 kuchokera zaka 5.
Kuyenderana ndi mowa
Pa mankhwala, kumwa mowa kumapangidwa.
Zokhudza mphamvu pakuwongolera njira
Zotheka zimachokera ku chapakati mantha dongosolo, kuphatikizapo chizungulire, kukomoka, masomphenya awiri, kusokonezeka kwa mgwirizano, kuyerekezera zinthu. Zizindikiro zotere zikawoneka, kugwira ntchito ndi njira zovuta ndizoletsedwa.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Chitetezo cha ciprofloxacin kwa mwana wosabadwayo sichinakhazikitsidwe, chifukwa chake, pa nthawi yokhala ndi pakati, azimayi sapatsidwa mankhwala. Ngati kuli kotheka kutenga mankhwala opatsirana ndi mayi woyamwitsa panthawi ya mankhwalawa, mwana ayenera kuthandizidwa kuti adyetsedwe.
Kusankhidwa kwa ana Columbrolet 250
Yogwira pophika mankhwala ikhoza kuyambitsa kupanga kwa arthropathy, chifukwa chake, kufikira zaka 18, mpaka matumba a cartilage a mafupa apangidwe, ndikosayenera kwambiri kugwiritsa ntchito mankhwala othandizira. Itha kuperekedwa kwa odwala omwe ali ndi zaka 5 kuti athetse ntchito ya Pseudomonas aeruginosa mu cystic fibrosis komanso ngati achire komanso prophylactic wothandizira wa anthrax (matenda a m'mapapo).
Analog ya Cyprolet 250 ndi Citral.
Bongo
Mukamamwa Mlingo wambiri, zizindikiro zake sizimawoneka. Zizindikiro za poyizoni, kupweteka mutu, kukokana, hematuria zimawonedwa, kutaya chikumbumtima ndikotheka. Pambuyo pa chifuwa cham'mimba, chithandizo chamankhwala chimachitika. Kugwiritsa ntchito dialysis, sizingatheke kuchotsa zoposa 10% za ciprofloxacin.
Kuchita ndi mankhwala ena
Kuphatikizika kwa ciprofloxacin ndi tizanidine ndikosavomerezeka. Izi zingayambitse kuchepa kwambiri kwa kupanikizika, chizungulire komanso kukomoka. Zotsatira za mankhwalawa zimatha kupititsidwa patsogolo ndi Vancomycin, Clindamycin, Tetracycline, Metronidazole, penicillin ndi aminoglycoside maantibayotiki, Zinnat ndi cephalosporins ena. Pamaso pake, plasma imagin ya anticoagulants, xanthines, hypoglycemic komanso anti-yotupa-non-hormones mankhwala (kupatula Aspirin) amawonjezeka.
Kuthana kwa ciprofloxacin kuchokera m'matumbo am'mimba kumalepheretsedwa ndikugwiritsa ntchito mankhwala okhala ndi aluminium, zinc, iron kapena magnesium ions, ndipo kutulutsa kwake kumachepetsedwa ndi kayendetsedwe ka Probenecid. Kugwiritsa ntchito munthawi yomweyo mankhwala omwe amafunsidwa ndi Cyclosporine kungayambitse kuchuluka kwa plasma creatinine.
Cyprolet 250 ndi mankhwala.
Analogs a Tsiprolet 250
Mankhwala ofanana ndi mankhwala:
- Ciprofloxacin;
- Tsiprova;
- Arflox;
- Athenoxime;
- Cypropane;
- Cigral
- Medociprine, etc.
Kupita kwina mankhwala
Maantibayotiki sanapangidwe kuti agulitsidwe kwaulere.
Kodi ndingagule popanda kulandira mankhwala?
Mankhwala ndi mankhwala.
Mtengo
Mtengo wamapiritsi ophatikizira enteric ndi wochokera ku ma ruble 56. kwa ma PC 10.
Zosunga Tsiprolet 250
Kutentha kosungira - mpaka + 25 ° С. Pewani chinyezi chachikulu komanso kuwonetsedwa ndi dzuwa.
Tsiku lotha ntchito
Mankhwalawa angagwiritsidwe ntchito mkati mwa zaka 3 kuyambira tsiku lopangira. Mankhwala omalizidwa ayenera kutayidwa.
Ndemanga ya Tsiprolet 250
Ma pharmacological wothandiziridwa amalandila amalimbikitsidwa kwambiri. Mayankho olakwika amaphatikizidwa ndi kuthekera kosavuta kwa pathogen kapena kulekerera koyipa nthawi imodzi.
Madokotala
Zinovieva T. A., otolaryngologist, Saratov
Mankhwala othandizira olimba, nthawi zambiri ndimagwiritsa ntchito zomwe ndimachita.
Tishchenko K.F., katswiri wamkulu, Moscow
Mankhwala abwino a antibacterial ndi regimen yabwino. Ndikupangira kutenga ndi probiotic kuti musunge microflora yamatumbo.
Odwala
Anna, wazaka 24, Rostov
Ndinamwa mapiritsi a cystitis. Mwansanga ndinapumula. Sindinazindikire mavuto aliwonse.
Tatyana, wazaka 56, Irkutsk
Chida chotsika mtengo komanso chothandiza. Ndinkamwa ndi chimfine chachikulu, kenako ndi furunculosis. Imalekeredwa bwino, mosiyana ndi maantibayotiki ena, ndipo samayambitsa thrush.
