Zochizira matenda a shuga, Mankhwala osiyanasiyana amagwiritsidwa ntchito, monga Diagnizide. Musanagwiritse ntchito, muyenera kuphunzira malangizo, popeza mankhwalawa ali ndi zotsutsana ndi zoyipa.
Dzinalo Losayenerana
Dzinalo losagwirizana ndi mayiko ena ndi Glyclazide.
Dzina ladziko lonse losagwirizana ndi mankhwalawa ndi Gliclazide.
ATX
Chogulitsachi chili ndi nambala yotsatirayi ya ATX: A10BB09.
Kutulutsa mafomu ndi kapangidwe kake
Gliclazide imagwira ntchito ngati yogwira ntchito. Zowonjezera ndizo hypromellose, Copovidone, magnesium stearate ndi silicon anhydrous colloidal dioxide. Mankhwalawa amasulidwa ngati mapiritsi 30 mg, atayikidwa mu chithuza cha ma PC 10. Katoniyo amakhala ndi matuza atatu kapena 6.
Momwe mungagwiritsire ntchito mankhwala Glyclazide?
Mankhwala Victoza amagwiritsidwa ntchito ndi odwala matenda ashuga komanso odwala omwe akufuna kuchepetsa thupi.
Ndi matenda ashuga, Mankhwala Mankhwala amathandiza bwino. Werengani zambiri za izo m'nkhaniyo.
Zotsatira za pharmacological
Wothandizila hypoglycemic amadziwika kuti ndi wochokera ku sulfanylurea. Zimathandizira kuchepetsa kupezeka kwa ma cell a beta-cell a ion a calcium, kumapangitsa kuti ma membrane azikhala ochepa, kumathandizira kuyendetsa ma calcium ayoni kudzera munjira ndikukulitsa zomwe zili ndi calcium ion mkati mwa maselo. Chifukwa cha izi, insulin imasiya ma kapisozi a cytoplasmic.
Chithandizo chogwira ntchito chimathandizira mphamvu ya insulin, kuchepetsa insulin, yomwe imachitika ndikugwiritsa ntchito kwambiri, yachepetsa kaphatikizidwe ka shuga mu chiwindi ndi kudzikundikira kwake mu minofu minofu. Kumwa mankhwalawa kumathandizira kupewa kupezeka kwa zotupa zam'mimba pamaso pa matenda a shuga, kuchepetsa maphatikizidwe ndi kuphatikizika kwa maselo, kumalimbikitsa minyewa ya fibronolytic ndikuwongolera kagayidwe ka prostaglandin.
Kumwa mankhwalawa kumathandiza kupewa mawonekedwe a zotupa za mtima pamaso pa matenda a shuga.
Kuphatikiza apo, mankhwalawa amawonedwa ngati amavomereza ma free radicals ndipo zimakhudza metabolidi ya lipid. Glyclazide amachepetsa kuchuluka kwa cholesterol mu plasma, amachepetsa kuchuluka kwa mafuta acids ndi triglycerides. Njira izi zimathandizira kuchepetsa kulemera kwa odwala omwe ali onenepa kwambiri.
Pharmacokinetics
Mutatha kumwa mapiritsi, amadziwikiridwa mwachangu m'mimba. Mlingo ndi kuchuluka kwa mayamwidwe sizimayimira kudya zakudya. Kuchuluka kwa mankhwalawa m'magazi kumawonedwa pambuyo pa maola 6 ndipo kumapitilira kwa maola 6-12.
Gliclazide metabolism imachitika m'chiwindi. Ma metabolabol amatuluka ndi mkodzo.
Zizindikiro zogwiritsidwa ntchito
Chipangizocho chikugwiritsidwa ntchito pochiza matenda osokoneza bongo omwe amadalira odwala matenda a shuga 2 odwala odwala akuluakulu, pomwe kuchuluka kwa glucose m'magazi sikungathe kulamulidwa ndi masewera olimbitsa thupi, kuchepa thupi komanso kudya.
Contraindication
M'pofunika kukana chithandizo chamankhwala ngati:
- Hypersensitivity zigawo zikuluzikulu;
- insulin wodalira shuga;
- kwambiri ketoacidosis;
- matenda a shuga kwa achinyamata ndi ana;
- matenda a shuga;
- dziko lokongola;
- kwambiri hepatic kapena aimpso kulephera.
Mankhwalawa ali ophatikizika mwa amayi apakati komanso oyamwa, komanso mwa odwala omwe amatenga Miconazole nthawi yomweyo.
Momwe mungatenge Diagnizide
Mankhwala amatengedwa pakamwa theka la ola musanadye 1-2 pa tsiku. Odwala omwe ali ndi mawonekedwe ofatsa matendawa amapatsidwa mlingo wa 80 mg, ndipo kwa odwala omwe ali ndi vuto lalikulu la matendawa, kuchuluka kwa mankhwalawa tsiku lililonse ndi 240 mg. Pafupipafupi dokotala amapereka odwala 320 mg tsiku lililonse.
Ndi matenda ashuga
Njira zochizira pamaso pa matenda a shuga zimatsimikiziridwa ndi katswiri, poganizira zomwe wodwalayo ali ndi zotsatira za mayeso.
Zotsatira zoyipa za Kuzindikira
Nthawi zina, thupi limayamba kugwa. Mwina vuto la metabolic mu mawonekedwe a hyponatremia.
Pa mbali ya gawo la masomphenyawo
Pakumayambiriro kwa chithandizo, mavuto ammaso amatha kuwoneka. Vutoli limachitika chifukwa cha kusintha kwa shuga m'magazi ndipo limadutsa kwakanthawi.
Matumbo
Kuchokera kugaya chakudya dongosolo kumaonekera mu mawonekedwe a nseru, kusanza, kupweteka kwam'mimba, kutsegula m'mimba, kukanika ndi kudzimbidwa. Zizindikiro zosasangalatsa zitha kupewedwa kapena kuchepetsedwa ngati mutsatira malangizo a dokotala ndikumwa mankhwalawo kamodzi pakudya kadzutsa.
Hematopoietic ziwalo
Zotsatira zoyipa zimatha kuchitika kumbali ya magazi ndi mitsempha ya m'mimba. Amawonetsedwa ndi mawonekedwe a thrombocytopenia, kuchepa magazi, granulocytopenia ndi leukopenia.
Pakati mantha dongosolo
Mankhwalawa, kugona, chizungulire, chisokonezo, kukhumudwa, komanso kukhumudwa kumawonekera.
Pa mbali ya chiwindi ndi biliary thirakiti
Kumwa mankhwalawa kungayambitse kuchuluka kwa michere ya chiwindi, hepatitis ndi cholestatic jaundice.
Matupi omaliza
Kupezeka koyipa mu mawonekedwe a urticaria, zotupa pakhungu, edema ya Quincke, kuyabwa, kuwonetsa kowopsa, ndi zotupa za maculopapullous sizimayikidwa.
Pa mankhwala, kupezeka kwa koyipa mu mawonekedwe a urticaria ndi zotupa pakhungu sikutsutsidwa.
Zokhudza mphamvu pakuwongolera njira
Wodwala ayenera kudziwa zizindikiro za hypoglycemia ndikuwazindikira pamene akuwongolera ndikuchita zinthu zomwe zimafunikira chidwi chochulukirapo komanso zochitika zapamtima zama psychomotor, makamaka poyambira chithandizo.
Malangizo apadera
Mapiritsi amalimbikitsidwa kwa odwala omwe amatsatira zakudya. Chiwopsezo cha dziko la hypoglycemic chikuwonjezeka ngati mafuta osakwanira amachokera ku chakudya kapena ngati satengedwa pa ndandanda. Kuti muwone momwe wodwalayo alili, ndikofunikira kugwiritsa ntchito mayeso a labotale kuti mupeze kuchuluka kwa shuga m'magazi.
Gwiritsani ntchito mu ukalamba
Kugwiritsa ntchito mankhwalawa ndi odwala okalamba kuyenera kuchitika moyang'aniridwa ndi katswiri wa zamankhwala chifukwa chowopsa cha hypoglycemia.
Kupatsa ana
Sizoletsedwa kugwiritsa ntchito mankhwalawa kuchiza ana chifukwa chosadziwa zambiri zokhudza chitetezo chake pagululi la odwala.
Kugwiritsa ntchito mankhwalawa ndi odwala okalamba kuyenera kuchitika moyang'aniridwa ndi katswiri wazachipatala.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Mankhwala ochepetsa shuga sagwiritsidwa ntchito munthawi ya bere. Ngati mimba yapezeka panthawi ya chithandizo, ndiye kuti mankhwala a hypoglycemic amayimitsidwa ndipo insulin imatengedwa. Ngati kuli kofunikira kuchita zochizira ndi Diagiside, kuyamwitsa kumasokonezedwa, chifukwa gawo lomwe limagwira limadutsa mkaka wa m'mawere ndipo lingayambitse hypoglycemia mwa mwana.
The ntchito aimpso kuwonongeka
Kulephera kwambiri kwa aimpso, chithandizo chiyenera kuyang'aniridwa ndi dokotala.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Kulephera kwambiri kwa chiwindi, mankhwalawa ndi diaglizide amachitika mosamala.
Kuchulukitsa kwa Diagnizide
Ngati mumagwiritsa ntchito mankhwalawa kuchuluka kwa mankhwalawa, mankhwala osokoneza bongo amatha kuchitika, monga zikuwonekera ndi zizindikiro za hypoglycemia. Ndi mawonekedwe ofatsa, mlingo ndi kusintha kwa zakudya pamafunika. Ndi kukula kwambiri kwa hypoglycemia, wodwalayo amafunika kuthandizidwa, motero amagonekedwa m'chipatala ndipo njira ya shuga imayendetsedwa kudzera m'mitsempha.
Zizindikiro za hypoglycemia zimawonetsa mankhwala osokoneza bongo.
Mankhwala ena amatsimikiziridwa ndi dokotala potengera momwe wodwalayo alili. Kugwiritsa ntchito dialysis pamenepa sikukutulutsa, chifukwa gliclazide imamangiriza mapuloteni a plasma. Kuphatikiza apo, okometsetsa sangakhale ndi zotsatira zomwe akufuna, chifukwa chake sayenera kugwiritsidwa ntchito.
Kuchita ndi mankhwala ena
Ndi munthawi yomweyo mankhwala angapo, zovuta zoyipa zitha kuchitika, chifukwa chake musanayambe chithandizo, muyenera kupita kwa katswiri kuti muchepetse vuto la zovuta.
Kuphatikiza kophatikizidwa
Amaphatikizidwa kuphatikiza Miconazole ndi Diagnizide, popeza dziko lamatenda a hypoglycemic limatha kukula.
Kuyenderana ndi mowa
Sizoletsedwa kumwa zakumwa zoledzeretsa ndi mankhwala omwe amakhala ndi mowa panthawi yamankhwala. Akaphatikizidwa ndi ethanol, chiopsezo cha hypoglycemia ndi chikomokere zimachuluka.
Sizoletsedwa kumwa zakumwa zoledzeretsa ndi mankhwala omwe amakhala ndi mowa panthawi yamankhwala.
Kuphatikiza komwe kumafunikira kusamala
Mosamala, khalani ndi chithandizo cha panthawi imodzi ndi Diabetesin ndi zinthu zotsatirazi:
- insulin;
- acarbose;
- bioganides;
- metformin;
- anticoagulants;
- fluconazole;
- beta blockers;
- Mao zoletsa;
- sulfonamides;
- clarithomycin;
- mankhwala osapweteka a antiidal;
- dipeptidyl peptidase-4 zoletsa;
- glucagon-ngati peptide-1 receptor agonists;
- ACE zoletsa.
Zinthu izi zitha kupititsa patsogolo zotsatira za hypoglycemic.
Osavomerezeka kuphatikiza
Kugwirizana kwa yogwira mankhwala ndi mowa ndi phenylbutazone kungayambitse zoipa zochita za thupi mu kuchuluka hypoglycemic kwenikweni. Ngati ndi kotheka, Mlingo wa hypoglycemic umasinthidwa nthawi ya phenylbutazone kapena pambuyo pake.
Analogi
Zithandizo zofananira izi:
- Glidiab;
- Glucosostable;
- Insuton;
- Chezerani;
- Zolemba;
- Predian.
Analogue imasankhidwa ndi katswiri atapima wodwalayo kwathunthu.
Kupita kwina mankhwala
Kuti mugule mankhwala, muyenera kulandira mankhwala kuchokera kwa dokotala.
Kodi ndingagule popanda kulandira mankhwala?
Popanda mankhwala, simungagule mankhwalawo ku pharmacy.
Mtengo
Mtengo wa mankhwalawa umatengera ndondomeko yamapulogalamu ndi ma 90 UAH ku Ukraine.
Zosungidwa zamankhwala
Malongedzedwe okhala ndi mapiritsi amayenera kuyikidwa pamalo owuma, amdima komanso osatheka ndi ana otentha osaposa + 25 ° C.
Tsiku lotha ntchito
Chogulitsacho chimasungabe zinthu zake zaka 3 kuyambira tsiku lopangidwa, malinga ndi malo osungira. Tsiku lotha litatha, mankhwalawo amatayidwa.
Wopanga
Kupanga kwa Diagliside kumachitika ndi Farmak OJSC.
Kuti mugule mankhwala, muyenera kulandira mankhwala kuchokera kwa dokotala.
Ndemanga
Antonina, wazaka 47, Krasnoyarsk: "Ndakhala ndikumwa mankhwalawa pamimba yopanda 60 mg patsiku kwa masabata angapo. Amamvanso bwino, ngakhale chizungulire komanso thukuta lidadetsa nkhawa m'masiku oyambira. Palibe zotsatira zina zoyipa."
Vladimir, wazaka 36, ku Moscow: "Ndakhala ndikudwala matenda ashuga kwa zaka zingapo. Mankhwalawa adathandizira kutsika magazi ndikuwonjezera thanzi langa, komanso kuphatikiza ndi kudya komanso kuchita masewera olimbitsa thupi. "
