Rotomox ndi mankhwala omwe amaperekedwa kuti athane ndi matenda opatsirana komanso kutupa. Ili ndi zochita zambiri. Komabe, zinthu zomwe zimapanga kapangidwe kake ndizomwe zimapangitsa kukhala zotsatira zoyipa. Wothandizira antimicrobial ali ndi contraindication. Musanayambe kugwiritsa ntchito, muyenera kufunsa dokotala.
Dzinalo Losayenerana
Mankhwalawa ali ndi INN - Moxifloxacin.
Rotomox wokhala ndi INN - Moxifloxacin, adayikidwa kuti athane ndi matenda opatsirana komanso otupa.
ATX
Kutchulidwa kwa atomic-achire-mankhwala kumawonetsa kuti Rotomox ndi wa antimicrobial wothandizirana ndi zonse. Malinga ndi code ya ATX J01MA14, mankhwalawa ndi zotumphukira za quinolone.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwalawa amapangidwa m'njira zingapo. Iliyonse yaiwo imakhala ndi mankhwala opangidwa ndi ma cell otchedwa moxifloxacin. Ndiye chinthu chachikulu chogwira ntchito.
Mapiritsi
Mapiritsi a Rotomox biconvex amapezeka mu mlingo wa 400 mg. Kumbali imodzi ya gawo lililonse la mankhwalawo amalembedwa ndi kuchuluka kwa maantibayotiki. Mankhwalawa amadzaza m'matumba ndikuyika m'matoni.
Madontho
Mankhwala amagulitsidwa mwanjira yamaponyoka amaso. Ndi chinthu chamdima chopepuka. Madontho amapangidwira kuti azigwiritsa ntchito kwanuko. Amapezeka m'mabotolo apadera okhala ndi ma nozzles kuti mugwiritse ntchito mosavuta.
Rotomox amagulitsidwa m'njira yamaso.
Njira Zothetsera
Njira yothetsera kulowetsedwa ili ndi mtundu wachikasu wonyezimira. Imathiridwa m'mbale zagalasi 250 ml. Mlingo wa moxifloxacin mu mtundu wa 400 mg. Mabotolo amaikidwa m'makatoni.
Zotsatira za pharmacological
Mankhwala ndi gawo limodzi la antiorojeni okhala ndi fluoroquinolone. Mphamvu yotsatsira ya mankhwalawa imawonetsedwa pakuwonekera kwa ma CD a cell ya pathogen, yomwe imatsogolera ku imfa ya mabakiteriya angapo aerobic gram-virus komanso gram-negative tizilombo. Zotsatira za moxifloxacin zimafikira pamitundu yotere ya microflora monga:
- Enterococcus faecalis;
- Staphylococcus aureus (kuphatikiza mitsempha yokhala ndi methicillin);
- Streptococcus anginosus, Streptococcus constellatus, Streptococcus pneumoniae (kuphatikiza penicillin ndi microlide zosagwira), Streptococcus pyogene (gulu A);
- Enterobacter cloacae;
- Escherichia coli;
- Haemophilus influenzae, Haemophilus parainfluenzae;
- Klebsiella pneumoniae;
- Moraxella catarrhalis;
- Proteus mirabilis.
Mankhwalawa amathandizira kupha mabakiteriya a grob-gramu komanso ma gram opanda tizilombo.
Ma microorganisms ena a anaerobic (Bacteroides fragilis, Bacteroides thetaiotaomicron, Clostridium perfringens, Peptostreptococcus spp.), Komanso othandizira matenda opatsirana, mwachitsanzo, Chlamydia pneumoniae, Mycoplasma pneumoniae, amamva mankhwala.
Pharmacokinetics
Moxifloxacin amalowetsedwa mwachangu ndikulowetsa chotupa ndi magazi. Ndi pakamwa makonzedwe, pazipita ndende ya yogwira zimawonedwa pambuyo pafupifupi mphindi 60. Mtheradi bioavailability wa mankhwalawa ndi 91%. Pa mlingo wa 50-1200 mg ndi muyezo umodzi kapena 600 mg / tsiku kwa masiku 10, pharmacokinetics imakhala yolondola, palibe chifukwa chosinthira kuchuluka kwa mankhwalawa kutengera zaka komanso jenda.
Zomwe zimagwira zimagwira mapuloteni a plasma ndi 40-42%.
Malovu, kuchuluka kwa mankhwala opangira mankhwala kumakhala kwakukulu. Kugawidwa kwa mankhwala opha maantibayotiki kumaonekeranso mu minyewa ya kupuma komanso kwamikodzo, madzi achilengedwe.
Mankhwalawa amachotsedwa m'thupi kudzera mu impso ndikugaya chakudya, osasinthika pang'ono komanso mawonekedwe a metabolites osagwira. Hafu ya moyo ndi maola 10-12.
Mankhwalawa amachotsedwa m'thupi kudzera mu impso.
Zizindikiro zogwiritsidwa ntchito
Kulandila Rotomoks zotchulidwa zovuta zochizira matenda a pakhungu ndi zimakhala zofewa. Mankhwalawa amagwiritsidwa ntchito pothana ndi chibayo chomwe anthu amapeza m'magulu, pokhapokha ngati mankhwala othandizira antioxotic ena pogwiritsa ntchito mankhwala ena sangathandize. Mankhwalawa akuwonetsa mabakiteriya am'mimba komanso am'munsi kupuma komanso ziwalo za ENT (pachimake sinusitis, bronchitis).
Contraindication
Fluoroquinolones amatsutsana panthawi ya bere komanso nthawi yoyamwitsa. Mankhwalawa amaletsedwa kwa ana osakwana zaka 18. Sitikulimbikitsidwa kumwa mankhwala akumwa khunyu komanso matenda opatsirana osiyanasiyana, kuphatikiza mwa anthu omwe ali ndi vuto la ubongo kapena omwe adwala mikwingwirima komanso mutu. Kusalolera wa antioxotic ndi kuponderezana kwachindunji. Osamamwa mankhwala ndi electrolyte imbalance.
Ndi chisamaliro
Mankhwalawa ayenera kugwiritsidwa ntchito mosamala kwambiri mu matenda a chiwindi ndi impso. Odwala omwe amafunikira kuperekera kwa hypoglycemic wothandizila amayenera kuyang'aniridwa ndi fluoroquinolone moyang'aniridwa ndi akatswiri nthawi zonse chifukwa choopsa chakuchepa kwambiri kwa shuga. Kwa anthu achikulire, mankhwalawa amatha kuyambitsa kupindika kwa tendon.
Mankhwalawa ayenera kugwiritsidwa ntchito mosamala mu matenda akulu a chiwindi.
Momwe mungatenge Rotomox?
Mapiritsi amatha kutengedwa, ngakhale nthawi yakudya. Mu sinusitis pachimake, tikulimbikitsidwa kumwa 400 mg ya mankhwala kamodzi patsiku. Njira ya chithandizo imatenga sabata. Ndi chibayo chopezeka m'deralo, mankhwalawa amapitilira malinga ndi zomwezo, koma nthawi yake imachulukitsidwa. Kulimbana ndi zilonda zamkati zopweteka za pakhungu ndi minofu yofewa kumafunikira kutenga maantibayotiki kwa masiku 21.
Ngati dokotala atayikira kukhuthala kwa mankhwalawa, ndiye kuti nthawi zambiri amasakanikirana ndi 0,9% sodium kolorayidi kapena 5% dextrose solution. Mlingo wa mankhwalawa ndi 250 ml (400 mg) kamodzi patsiku. The kulowetsedwa kumatenga mphindi 60.
Ndi matenda ashuga
Anthu omwe ali ndi matenda ashuga ayenera kusamala mukamalandira chithandizo, chifukwa kuphatikiza ndi ma hypoglycemic othandizira, kutenga Rotomox kumatha kupangitsa kutsika kwamphamvu m'magazi a shuga.
Zotsatira zoyipa
Mankhwalawa amayambitsa zovuta zingapo zomwe zimatha kusintha. Poyamba zizindikiro zoyipa za thupi, ndikofunikira kusiya kugwiritsa ntchito mankhwalawo ndikuonana ndi dokotala.
Pachizindikiro choyambirira chosagwirizana ndi Rotomox, muyenera kufunsa dokotala.
Kuchokera minofu ndi mafupa
Zinthu zomwe zimagwira mu Rotomox zimatha kupangitsa chitukuko cha arthralgia, myalgia. Mukukula, mankhwala amatha kuyambitsa Achilles tendon tendonitis.
Matumbo
Kuchita kwa moxifloxacin pamatumbo ammimba nthawi zambiri kumayendetsedwa ndi zinthu monga mseru, kusanza, kutsekula m'mimba kapena kudzimbidwa, kuphwanya pansi. Pseudomembranous enterocolitis, kuwonjezeka kwa ntchito ya hepatic transaminases, ndi chitukuko cha cholestatic jaundice sichimachotsedwa. Odwala nthawi zambiri amamva kupweteka kwam'mimba komanso pakamwa lowuma. Kugwiritsa ntchito maantibayotiki kumapangitsa kusokoneza kwa microflora yamatumbo ndipo ndikuyambitsa dysbiosis.
Hematopoietic ziwalo
Kugwiritsa ntchito mankhwalawa kwa nthawi yayitali kumakhudza ntchito ya hematopoiesis. Pa mankhwala opha maantibayotiki, leukopenia, thrombocytopenia, neutropenia, ndi hemolytic anemia.
Pakati mantha dongosolo
Moxifloxacin amakwiya chizungulire, migraine, kugona tulo. Mankhwalawa amatha kuyambitsa kupsinjika, paresthesia, nkhawa zowonjezereka, kugwedezeka kwa malekezero.
Nthawi zina, odwala amakhala ndi chisokonezo, kukhumudwa, kulumikizana kosayenera ndikuyang'ana m'malo ovuta. Maonekedwe akuwonongeka kwamawonedwe, kuchepa kwa kumva mphamvu, kumva kukoma, kununkhiza ndi zovuta zina sizimalamulidwa.
Kuchokera ku genitourinary system
Kutenga Rotomox kumatha kuwononga kwambiri impso. Mwina kukula kwa interstitial cystitis. Akazi nthawi zambiri amakhala ndi vagidi candidiasis.
Kuchokera pamtima
Yogwira pophika mankhwala imachulukitsa nthawi ya QT ndipo ndiyomwe imayambitsa kupindika kwamitsempha yamagazi. Pa mankhwala opha maantibayotiki, tachycardia ikhoza kukhala, edema imawonekera, kulumpha kwakuthwa mu kuthamanga kwa magazi ndi hypotension sikukutulutsidwa.
Matupi omaliza
Mankhwalawa amayambitsa ziwonetsero zosiyanasiyana, monga kuyabwa, zotupa pakhungu, ndi ming'oma. Kugwedezeka kwa anaphylactic ndi edema ya Quincke ndizosowa.
Zokhudza mphamvu pakuwongolera njira
Moxifloxacin amawononga ntchito zama psychomotor. Anthu omwe amagwirizana ndi magalimoto oyendetsa kapena zida zina zovuta ayenera kusamala pa nthawi ya quinolone.
Anthu omwe amagwirizana ndi kuyendetsa ayenera kusamala nthawi ya Rotomox.
Malangizo apadera
Pali nthawi zina pamene kutenga Rotomox kuyenera kuchitika moyang'aniridwa ndi dokotala. Kutengera chithunzithunzi cha matenda ndi zodwala matenda, kusintha mtundu wa mankhwala kungafunike. Nthawi zina, kumwa maantibayotiki ndizoletsedwa.
Gwiritsani ntchito mu ukalamba
Okalamba omwe alibe mbiri yovuta ya chiwindi, impso ndi mtima, kuchepetsa mlingo sikufunika. Komabe, pazizindikiro zoyambirira za kuphatikizika kwa m'mimba, muyenera kusiya kumwa mankhwalawo, chifukwa pamakhala chiwopsezo cha kupasuka kwa tendon.
Kupangira Rotomox kwa ana
Kwa ana ochepera zaka 18, mankhwalawa amatsutsana.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Pa nthawi yoyembekezera, mankhwalawa moxifloxacin saloledwa, popeza zigawo zikuluzikulu zimalowa mkati mwa chotchinga komanso zimasokoneza chitukuko cha mwana wosabadwayo. Mukamayamwa, mankhwala oletsa mankhwalawa amaletsedwanso. Ngati pakufunikira mankhwala othandizira antimicrobial mwa mayi, mwana amasamutsidwa ku zakudya zopatsa mphamvu.
Pa nthawi yapakati, chithandizo ndi Rotomox sichimaloledwa.
The ntchito aimpso kuwonongeka
Ngati aimpso ntchito, m`pofunika kuchepetsa tsiku mlingo wa antibacterial wothandizira. Ndi chilolezo chotsika cha creatinine, 400 mg ya mankhwalawa imatengedwa tsiku loyamba, ndiye kuti voliyumu imachepetsedwa mpaka 200 mg.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Anthu omwe ali ndi vuto la chiwindi kwambiri ayenera kumwa mankhwalawa mosamala.
Bongo
Milandu yakufa ya Rotomox bongo wosapitilira siyinalembedwe. Koma kupitilira kuchuluka kwake kwa mankhwalawa kumatha kuyambitsa mseru komanso kusanza, chisokonezo, pseudomembranous enterocolitis ndi kupweteka. Palibe mankhwala enieni. Hemodialysis siyothandiza. Mu maora awiri oyambilira mutatha kumwa mankhwala ambiri, tikulimbikitsidwa kuti muzimutsuka m'mimba, kumukoka makala. Kenako wodwala amafunikira chithandizo chamankhwala.
Kuchita ndi mankhwala ena
Akaphatikizidwa, Ranitidine amachepetsa kuyamwa kwa Rotomox. Maantacid okhala, othandizira pakudya, mavitamini, kukonzekera komwe kumakhala ndi chitsulo, potaziyamu, magnesium, aluminium, amapanga zovuta kusungunuka ndi maantibayotiki ndikuchepetsa kuchuluka kwake. Mankhwalawa amayenera kumwedwa pakapita maola awiri.
Akaphatikizidwa, Ranitidine amachepetsa kuyamwa kwa Rotomox.
Mankhwala osavomerezeka kuti atengedwe limodzi ndi othandizira a hypoglycemic chifukwa choopsa cha kuchepa kwambiri kwa shuga m'magazi. Glucocorticosteroids angayambitse kupindika kwa tendon. Ma anticoagulants osagwiritsidwa ntchito pakamodzi pakamwa amathandizira kukha magazi. Mankhwala osagwirizana ndi antisteroidal omwe amaphatikizana ndi Rotomox amatsogolera ku kukoka.
Kuyenderana ndi mowa
Mankhwala sayenera kumwedwa ndi zakumwa zoledzeretsa. Mowa umachepetsa mphamvu ya maantibayotiki ndikuwonjezera zoyipa.
Analogi
Analogues a mankhwalawa ndi mankhwala monga Maxiflox, Plevilox, Moximac, Vigamox, Avelox. Maantibayotiki ali ndi moxifloxacin. Mutha kusintha mankhwalawo ndi fluoroquinolones ena: Levofloxacin, Nolitsin, Norfloxacin, Ofloxacin. Dokotala amapanga kusankha kwa mankhwalawa kutengera zotsatira za mayeso a labotale komanso mbiri ya wodwalayo. Sikulimbikitsidwa kusankha nokha.
Malo opumulirako a Rotomox ku pharmacy
Malamulo opatsirana a Rotomox kuchokera ku mankhwala apadera ndi othandizira kupatsa mankhwala antimicrobial.
Kodi ndingagule popanda kulandira mankhwala?
Mankhwalawa amagulitsidwa kokha ndi mankhwala.
Mtengo wa Rotomox
Mtengo wa mankhwalawa umatengera mtundu wake. Mtengo wokulongedza mapiritsi ku Russia umachokera ku ma ruble 450-490.
Zosungidwa zamankhwala
Mapiritsi ndi yankho la kulowetsedwa ziyenera kusungidwa kutali ndi dzuwa mwachindunji ndi magetsi othandizira, m'malo owuma osatheka ndi ana. Kutentha kwa chipinda kuyenera kukhala koyenera.
Rotomox ili ndi analog Nolitsin, omwe amasungidwa kutali ndi dzuwa mwachindunji ndi zida zamagetsi.
Tsiku lotha ntchito
Mankhwalawa ndi oyenera kwa miyezi 24 kuyambira tsiku lopangidwa.
Wopanga Rotomox
Mankhwalawa amapangidwa ndi Scan Biotech Limited (India).
Ndemanga za odwala za Rotomox
Victoria, wazaka 35, Yuzhno-Sakhalinsk
Anamuthandiza bronchitis wodwala Rotomox. Mankhwalawa mwachangu adachotsa zizindikiro za kufalikira, adatenga sabata limodzi. Panalibe zovuta zoyipa, koma mutu wokhazikika unkasokoneza.
Larisa, wazaka 28, Magnitogorsk
Anatenga maantibayotiki pachimake sinusitis. Ena sanathandizenso. Kenako ndimafunika kuchapa, ngakhale ndimadya moyenera komanso ukhondo. Sindingafune kuyesanso izi pa thanzi langa.
Madokotala amafufuza
Alexander Reshetov, Otolaryngologist, Tver
Kugwiritsa ntchito maantibayotiki kumakhala koyenera ngati wopatsirana asawonetse kukhudzidwa kwa mankhwala ena. Muzochitika zina zonse, ndikofunikira kusankha mankhwala ochepera.
Valeria Mironchuk, dotolo, Lipetsk
Zotsatira zoyipa zitha kupewedwa ngati mulingo womwewo wawerengedwa molondola komanso matenda ena obwera amakumbukiridwa. Mukakalamba ndibwino kuti musadziike pachiwopsezo. Sichigwiritsidwa ntchito kawirikawiri pochiza matenda a kwamikodzo thirakiti. Koma nthawi zina, mankhwalawa ndiofunikira.
