Glidiab - malangizo a momwe mungasinthire komanso ndalama zake

Glidiab amadziwika ndi pafupifupi aliyense wodwala matenda ashuga. Muli gliclazide - chinthu chotchuka kwambiri chopezeka kuchokera ku sulfonylurea. Chifukwa chogwira ntchito komanso kupezeka, mankhwalawa ochokera ku gululi amaperekedwa padziko lonse lapansi kwa odwala ambiri omwe ali ndi matenda ashuga.

Mapiritsiwo amapangidwa ndi Akrikhin, omwe ndi amodzi mwa omwe amapanga mankhwala ku Russia. Glidiab ali ndi kuthekera kwakukulu kwa hypoglycemic, chithandizo chimalola kuti achepetse hemoglobin ya glycated mpaka 2%. Mbali yolumikizana ndi izi ndi chiopsezo cha hypoglycemia.

Kodi Glidiab MV

Pamafunika kuwongolera glycemic popewa zovuta za shuga. Monga lamulo, dongosolo la mankhwalawa limaphatikizanso kukonza kwa zakudya komanso ntchito. Ndi nthenda yachiwiri, njirazi nthawi zambiri sizikhala zokwanira, chifukwa chake pamakhala kufunsa kwa mankhwala ochepetsa shuga. Gawo loyambirira la matendawa limadziwika ndi kukana insulini komanso kuchuluka kwa shuga m'chiwindi, motero panthawiyi mankhwala othandiza kwambiri ndi metformin (mwachitsanzo, Glucofage).

Matenda oopsa a hyperglycemia munthawi yochepa imayambitsa kukanika kwa maselo osokoneza bongo komanso kuwonongeka kwa insulin. Kusintha koteroko kukayamba, ndikofunikira kuwonjezera mapiritsi pazomwe zimaperekedwa kale zomwe zingalimbikitse kupanga kwa insulin. Mwa mankhwala omwe alipo, DPP4 inhibitors, incretin mimetics, ndi sulfonylureas amatha izi.

Magulu awiri oyambawa amagwiritsidwa ntchito posachedwa, ngakhale kuti mankhwalawa ndi othandiza, koma okwera mtengo. M'madera ambiri a Russia, kuwapezera zaulere ndizovuta. Koma zotchipa za sulfonylureas zimatsimikiziridwa kuti zimayikidwa kuchipatala chilichonse. Mankhwala otetezedwa kwambiri komanso amakono kwambiri pa mankhwalawa ndi glimepiride (Amaryl) ndi mtundu wosinthika wa glyclazide (Diabeton MV ndi mayendedwe ake, kuphatikiza Glidiab MV)

Matenda a shuga ndi kupsinjika kudzakhala chinthu chakale

• Matenda a shuga -95%
• Kuthetsa kwa mitsempha thrombosis - 70%
• Kuthetsa kwa kugunda kwamtima kwamphamvu -90%
• Kuthana ndi kuthamanga kwa magazi - 92%
• Kuwonjezeka kwa mphamvu masana, kukonza kugona usiku -97%

Diabetes ndi mankhwala oyamba, Glidiab ndi generic wabwino. Kafukufuku watsimikizira zofanana za mankhwalawa pa glycemia.

Malangizo ogwiritsira ntchito amafotokozera zochita zingapo za Glidiab:

1. Kubwezeretsanso gawo loyamba la kupanga insulin, chifukwa chomwe shuga amayamba kusiya ziwiya atangolowa.
2. Kukweza 2 magawo.
3. Kuchepetsa kuphatikiza kwa maselo am'magazi, kukonza mphamvu ya epithelium yamasamba kuti isungunuke. Izi zimachepetsa mwayi wamisempha yamavuto.
4. Kusasinthika kwa ma radicals aulere, kuchuluka kwake kumawonjezeka ndi matenda a shuga.

Pali maphunziro omwe akuwonetsa kuti kukonzekera kwa sulfonylurea kumabweretsa kuwonongeka kwa maselo a beta, kumabweretsa kuchepa kwa insulini ndikukakamiza odwala matenda ashuga kuti asinthe kupita ku insulin. Glidiab m'gulu lake ndi imodzi mwamankhwala otetezeka pankhaniyi. Mlingo wamba wa mankhwalawa umachulukitsa kuphatikiza kwa mahomoni ndi 30%, pambuyo pake kupanga kwake kumatsika ndi 5% pachaka chilichonse. Munjira yachilengedwe matendawa, kusowa kwa insulin kumawonjezeka chaka chilichonse ndi 4%. Ndiye kuti, sizingatheke kuyitanitsa Glidiab kwathunthu chifukwa cha kapamba, komanso sizingafanane ndi mankhwala olimba ochokera ku gulu lomweli, mwachitsanzo, Maninil.

Zisonyezero zoika mankhwalawa

Malinga ndi malangizo, Glidiab amalembedwa kokha kwa odwala matenda ashuga omwe ali ndi mitundu iwiri ya zovuta za carbohydrate. Zochita za mankhwala zimayendetsedwa mwachindunji kwa maselo a beta, omwe palibe mtundu 1 wa shuga. Kuchiza kuyenera kuphatikizidwa ndi zakudya komanso masewera olimbitsa thupi, kunenepa kwambiri komanso / kapena kukana insulin, metformin imawonjezeredwa.

Glidiab adalembedwa ngati kuwonjezera kwa metformin pokhapokha wodwala akamaliza kutsatira zonse zomwe akupatsidwa, koma osatha kufikira glycemia yomwe akufuna. Monga lamulo, izi zikuwonetsa kuchepa kwa gawo la pancreatic ntchito. Kuti muwonetse kuchepa kwa insulin komanso kufunikira kwa Glidiab, ndikofunika kuti ayese mayeso a C-peptide.

Kumayambiriro kwa matendawa, mankhwalawa amalembedwa pokhapokha ngati magazi a m'magazi ndi okwera kwambiri, ndipo amakayikira kuti matenda a shuga adapezeka zaka zingapo pambuyo pake momwe adayambira.

Mlingo ndi mawonekedwe

Wopanga amatulutsa Glidiab m'mitundu iwiri:

1. Mlingo wa Glidiab wa 80 mg. Awa ndi mapiritsi achikhalidwe omwe ali ndi gliclazide, zinthu zomwe zimagwira kuchokera kwa iwo zimatengedwa mwachangu m'magazi ndikufika pachimake patatha maola 4. Inali nthawi imeneyi kuti chiopsezo chachikulu kwambiri cha hypoglycemia. Mlingo wapamwamba pa 160 mg umagawidwa mu 2 Mlingo, kotero shuga imatha kutsika mobwerezabwereza masana.
2. Glidiab MV ndiwowoneka bwino kwambiri, mapiritsiwo amapangidwa mwanjira yoti gliclazide kuchokera kwa iwo imalowera magazi pang'onopang'ono komanso moyenera. Izi ndiye zomwe zimatchedwa kuti kusinthidwa, kapena kupitilira. Chifukwa cha izo, zotsatira za Glidiab zimawonjezeka bwino komanso kwa nthawi yayitali zimasungidwa chimodzimodzi, zomwe zimawonjezera mphamvu ya mankhwalawa, zimachepetsa muyeso wofunikira, komanso kupewa hypoglycemia.

Kusiyana kwa mtengo pakati pa mankhwalawa ndizochepa - Glidiab MV ndi okwera mtengo kwambiri ma ruble 20, ndipo kusiyana kotetezako ndikofunikira, motero, wopanga akuvomereza kuti odwala matenda ashuga asinthane ndi mankhwala atsopano. Malinga ndi kuthekera kwake, piritsi limodzi la Glidiab 80 ndilofanana ndi piritsi limodzi la Glidiab MV 30.

Mlingo Walimbikitsa:

Lamulo la kuwonjezera kuchuluka kwa mankhwalawa malinga ndi malangizo ogwiritsira ntchito: ngati mlingo woyambira ungakhale wokwanira, utha kuwonjezeredwa ndi 30 mg (80 kwa Glidiab wokhazikika) pakatha mwezi wokhazikitsidwa. Mutha kuwonjezera kuchuluka kwa odwala matenda ashuga okha omwe shuga ya magazi sinasinthe. Kukula msanga kwamankhwala oopsa kumakhala kowopsa ndi chikomokere.

Momwe mungagwiritsire ntchito Glidiab

Malinga ndi madokotala, odwala omwe ali ndi matenda osakhazikika samamwa mankhwala onse omwe apatsidwa. Ndi matenda a 2 a shuga, zovuta sizingokhala ndi glucose wambiri, motero odwala amakakamizidwa kumwa ma statins, aspirin, ndi mankhwala othamanga ndi magazi kuphatikiza pa mankhwala ochepetsa shuga. Mankhwala ambiri amakhala ndi mankhwalawo komanso akamathandizira kuchuluka kwa mankhwalawo, amachepetsa mwayi woti amwa moledzera. Glidiab MV amatengedwa kamodzi patsiku, mosasamala za kuchuluka kwa mankhwala, motero, sakonda kuphonya mlingo.

Zotsatira zake zoyipa

Mndandanda wazotsatira zoyipa zomwe zimatheka mukamatenga Glidiab MV 30 mg ndi mawonekedwe ake:

1. Hypoglycemia imachitika ndi mankhwala osokoneza bongo, ndikulumphira chakudya kapena kuperewera kwa chakudya m'matimu. Kutsika kofupipafupi kwa shuga kumafunikira kukonzanso kwa zakudya ndi kuchepetsa kwa glidiab.
2. Matenda am'mimba. Kuchepetsa chiopsezo cha mbali iyi, malangizowo akutsimikiza kuti mutenge Glidiab nthawi yomweyo ndi chakudya.
3. Zikopa. Malinga ndi ndemanga, zotsatira zoyipa zambiri za thupi sizimachitika.
4. Sinthani muzomwe zili m'magazi. Nthawi zambiri zimasinthidwa, ndiye kuti, zimadzipezeka zokha zitatha kuvomereza.

Kuopsa kwa hypoglycemia akuti pafupifupi 5%, komwe kumatsika kwambiri poyerekeza ndi sulfonylureas yakale. Anthu omwe ali ndi matenda a shuga mellitus osakanikirana ndi matenda oopsa a mtima ndi endocrine, komanso kumwa ma hormone kwa nthawi yayitali, amakonda kutsika shuga. Kwa iwo, muyeso wovomerezeka wa Glidiab ndi wochepa mpaka 30 mg. Anthu odwala matenda ashuga omwe ali ndi vuto la neuropathy, okalamba, odwala omwe amakhala ndi nthawi yayitali kapena amakhala ndi nthawi yayitali, amasiya kumva zizindikiro za shuga wochepa, motero kutenga Glidiab kungakhale koopsa kwa iwo. Pankhaniyi, mapiritsi a shuga omwe alibe zotsatira zoyipa zotere amavomerezeka.

Contraindication

Glidiab ikhoza kukhala yoyipa:

1. Mankhwalawa adayesedwa okha odwala matenda ashuga, momwe amawonera matupi a ana sanaphunziridwe, chifukwa chake, sawerengedwa mpaka zaka 18, ngakhale mwana atatsimikizira mtundu wachiwiri wa matenda.
2. Pakukomoka kwa matenda ashuga komanso momwe zinthu zakhalira patsogolo pawo, ndi mankhwala a insulin okha omwe amagwiritsidwa ntchito. Mapiritsi aliwonse omwe amachepetsa shuga, kuphatikiza Glidiab ndi mawonekedwe ake, amachotsedwa kwakanthawi.
3. Glyclazide imaphwanyidwa ndi chiwindi, pambuyo pake metabolites wake amuchotsa mkodzo. Pankhaniyi, kutenga Glidiab ndi koletsedwa kwa odwala matenda ashuga kwambiri aimpso komanso kwa chiwindi.
4. The antifungal miconazole imathandizira kwambiri zotsatira za Glidiab ndipo imatha kuputa chikumbumtima cha hypoglycemic, chifukwa chake olamulira mogwirizana saloledwa ndi malangizo.
5. Pakati pathupi ndi pakubala, gliclazide imatha kulowa m'magazi a mwana, chifukwa chake singatenge nthawi imeneyi.

Mafanizo otchuka

Pakati pa mapiritsi a antiidiabetesic pochiza matenda amtundu 2, ndimakonzedwe a glyclazide omwe amagawa kwambiri. Metformin ndi okhawo omwe angapikisane nawo mu kuchuluka kwa mayina olembetsedwa. Mitundu yambiri ya Glidiab imapangidwa ku Russia, mtengo wawo m'masitolo amasiyana pakati pa ma ruble a 120-150, mtengo wa French Diabeteson wodula kwambiri umakhala pafupifupi ma ruble a 350.

Ma analogi a Glidiab ndi choloweza mmalo:

Glidiab kapena Gliclazide - ndibwino?

Ubwino wa mankhwala umatsimikiziridwa ndi kuchuluka kwa kuyeretsedwa ndi kulondola kwa mulingo wa chinthu chomwe chikugwira, chitetezo cha zigawo zothandizira. Glidiab ndi Glyclazide (kupanga Ozone) ali ofanana mwamitundu iyi. Akrikhin ndi Ozone onse ali ndi zida zamakono, makampani onsewa sadzipangira okha mankhwala, koma amagula, kuwonjezera apo, kuchokera kwa omwe amapanga aku China omwe. Ndipo kapangidwe kamakomedwe, Glidiab ndi Gliclazide pafupifupi amabwerezananso. Kuunika kwa anthu omwe amamwa mankhwalawa kwa nthawi yoposa chaka chimodzi kumatsimikiziranso kuyesayesa kwawo kofanana mu shuga.

Glyclazide ili ndi mitundu iwiri ya kusankha - 30/60 mg, Glidiab - 30 mg yokha; Glidiab imatha kusinthidwa ndikumasulidwa kwachizolowezi, Gliclazide imangotulutsa - ndiye kusiyana konse pakati pamapiritsi awa.

Ndemanga Zahudwala