Diabetesalong ali ndi kumasulidwa kosasintha (PV) kapena kumasintha kosinthika (MV) komwe kumagwiritsidwa ntchito mtundu wa 2 shuga. Ndi m'gulu lachiwiri la sulfonylurea.
Kugwiritsidwa ntchito kwake kumachitika chifukwa chakuti nthawi zina zimakhala zovuta kwambiri kuyendetsa matenda amtunduwu ndi chakudya chimodzi komanso zolimbitsa thupi. Zomwe zimachitika nthawi zonse mu shuga ndi zizindikiro za hyperglycemia ziyenera kuwongoleredwa.
Chithandizo cholakwika cha matenda ashuga osaneneka chimayambitsa mavuto ambiri, owopsa kwambiri ndi mtima. Kumwa mankhwala a Diabetesalong kumachepetsa mwayi wokhala ndi matenda ochepa komanso ochepa. Nkhaniyi ikuthandizani kudziwa momwe mungamwe mankhwalawo moyenera.
Pharmacological zochita za mankhwala
Kuchepetsa shuga kwa mankhwalawa Diabetesalong kumalumikizidwa ndi gawo limodzi - glycoslazide. Piritsi lililonse limakhala ndi 30 kapena 60 mg ya chinthu chachikulu komanso zochepa zowonjezera: hypromellose, calcium stearate, talc, lactose monohydrate, komanso colloidal silicon dioxide.
Gliclazide amadziwika kuti ndi ena amachokera ku sulfonylurea, monga zinanenedwa kale. Kamodzi m'thupi, gawo ili limayamba kulimbikitsa kupanga kwa insulin ndi maselo a beta omwe amapanga zida za islet.
Tiyenera kudziwa kuti ngakhale patatha zaka ziwiri chithandizo ndi mankhwalawa, kuchuluka kwa C-peptide ndi insulin ya postprandial imatsala. Ndipo, gliclazide ili ndi zotsatirazi:
- Malangizo a kagayidwe kazakudya;
- kukondoweza kwa insulin;
- hemovascular.
Wodwala akadya chakudya kapena kuwonetsa glucose mkati, gliclazide imayamba kuyambitsa kupangika kwa mahomoni. Mphamvu ya hemovascular imachitika chifukwa chakuti chinthucho chimachepetsa mwayi wa thrombosis wa ziwiya zazing'ono. Kulandila kosalekeza kumalepheretsa chitukuko cha:
- Microvascular pathologies - retinopathy (kutupa kwa retina) ndi nephropathy (kuwonongeka kwa impso).
- Zotsatira za macrovascular - stroko kapena myocardial infarction.
Pambuyo pakulowetsa, gliclazide imalowa lonse. Kuyika kwake m'magazi kumachulukanso, nsapatozo zimawonedwa patatha maola 6 mutatha kugwiritsa ntchito mankhwalawa. Kutalika kwa kuchitapo kanthu kuchokera pa maola 6 mpaka 12. Kudya sikukhudza kuyamwa kwa chinthu. Glyclazide imakumbidwa makamaka ndi impso, theka la moyo wawo limasiyana maola 12 mpaka 20.
Mankhwalawa amayenera kusungidwa m'malo omwe amatha kupezeka ndi kuwala kwa dzuwa ndi maso a mwana wocheperako, kutentha osaposa 25 digiri. Alumali moyo wa mankhwala ndi zaka 3.
Malangizo ogwiritsira ntchito mankhwalawa
Choyamba, ziyenera kudziwidwa nthawi yomweyo kuti mapiritsi a Diabetalong adayikidwa kokha kuti athandize odwala. Musanayambe chithandizo, muyenera kufunsa dokotala yemwe akuwonetseni mtundu wa mankhwalawo ndikukupatsani kuchuluka kwa mankhwalawo, poganizira zomwe wodwala aliyense ali nazo.
Mutagula mankhwalawa Diabetesalong, malangizo ogwiritsira ntchito ayeneranso kuphunziridwa mosamala. Ngati mafunso ena abuka, ayenera kufunsidwa ndi katswiri wopezekapo.
Panthawi yoika mapiritsi kuti athandizire kukhala ochiritsika, ndikofunikira kutsatira malamulo awa:
- Amatengedwa pakamwa nthawi imodzi, makamaka m'mawa.
- Mlingo umodzi ukhale wa 30 mpaka 120 mg patsiku.
- Piritsi siliyenera kutafunidwa, imameza yonse.
- Ngati mungadumphe kumwa mankhwalawo, simungawonjezere kuchuluka kwake.
- Mlingo wa mankhwalawa amasankhidwa payekha poganizira kuchuluka kwa shuga ndi HbAlc.
Mlingo woyambitsidwa ndi 30 mg tsiku lililonse, koma ngati wodwalayo sangathe kuyendetsa bwino shuga, ndiye kuti muyezo wake utha kuwonjezereka pogwirizanitsa izi ndi adokotala. Komabe, kuwonjezera kuchuluka kwa mankhwalawa sikunachitike kuposa mwezi umodzi wotsatira wa mankhwalawa. Koma ngati wodwalayo alephera kuchepetsa kuchuluka kwa shuga kwa milungu iwiri, ndiye kuti angathe kuwonjezera mlingo wa mankhwalawo.
Tiyenera kudziwa kuti piritsi limodzi la mankhwala a Diabetalong PV lili ndi 60 mg ya glycazide, yomwe imafanana ndi mapiritsi 2 a mankhwala a MV omwe ali ndi 30 mg
Mukasintha kuchoka ku mankhwala ena ochepetsa shuga kuti muthandizidwe ndi Diabetesalong, nthawi zambiri palibe zopuma zofunika. Kupatula kokha ndikugwiritsa ntchito mankhwala a sulfonylurea. Mlingo woyambirira wa mankhwalawa ndi 30 mg, ngakhale kuli bwino kuonana ndi dokotala.
Diabetesalong ikhoza kugwiritsidwa ntchito molumikizana ndi mankhwala a hypoglycemic monga biguanides, insulin ndi alpha-glucosidase inhibitors.
Mosamala, iyenera kugwiritsidwa ntchito ndi odwala omwe ali pachiwopsezo cha hypoglycemia.
Contraindication ndi zomwe zingavulaze
Mankhwalawa ali ndi zambiri zotsutsana. Amaphatikizidwa makamaka ndi ntchito ya impso, kapamba ndi chiwindi.
Kuphatikiza kuti Diabetesalong singatengedwe ndi anthu odwala matenda ashuga omwe ali ndi mawonekedwe a insulin omwe amadalira mankhwalawo, mankhwalawo amaletsedwa ndi:
- tsankho la munthu ku gliclazide ndi zinthu zina;
- matenda ashuga, precoma, chitukuko cha matenda ashuga ketoacidosis;
- kwambiri aimpso kapena chiwindi kulephera;
- munthawi yomweyo kugwiritsa ntchito miconazole;
- wokhala ndi mwana ndi kuyamwa;
- lactose tsankho, shuga-galactose malabsorption ndi kuchepa kwa lactase;
- ana ochepera zaka 18.
Mankhwalawa amayenera kuthandizidwa mosamala kwambiri okalamba odwala matenda ashuga, komanso:
- chakudya chopanda malire;
- shuga-6phosphate dehydrogenase akusowa;
- hypothyroidism;
- hypoituitarism;
- pituitary kapena adrenal insuffence;
- kudya zakumwa zoledzeretsa kosalekeza;
- aimpso ndi / kapena kulephera kwa chiwindi;
- chithandizo cha nthawi yayitali ndi glucocorticoids.
Diabetesalong yotsitsa msuzi iyenera kutengedwa, powona mitundu yonse ndi malingaliro a katswiri. Kudumpha mapiritsi, kudya mosasamala, kapena kumwa mopitirira muyeso kumatha kuyambitsa mavuto osiyanasiyana. Zowopsa zomwe zitha kukhala:
- Kukula kwa dziko la hypoglycemic. Amadziwika ndi zizindikiro zambiri, mwachitsanzo, kupweteka mutu komanso chizungulire, njala, kudzimbidwa, kukhumudwa, kusokonezeka, kulephera, kudziletsa, kupenya bwino, kupumira kwambiri komanso kugunda kwa mtima.
- Maonekedwe a adrenergic zimachitika. Izi zimaphatikizira thukuta, nkhawa, kuchuluka kwa magazi, angina pectoris, arrhythmia, ndi tachycardia.
- Kusokoneza kwam'mimba, komwe kumawonetsedwa ndi kupweteka kwam'mimba, kupuma mseru ndi kusanza, kutsekula m'mimba kapena kudzimbidwa.
- Khungu limatulutsa ngati pruritus, zidzolo, edema ya Quincke, urticaria, erythema, zotupa za maculopapular, kapena kupweteketsa mtima.
- Hemopoiesis ntchito kuwonongeka - kuchepa magazi, thrombocytopenia, leukopenia ndi granulocytopenia.
- Kuchepa kwa chiwindi ndi njira ina yothandizira, yomwe ikuwonetsedwa ndi chiwindi, kuwonjezeka kwa ntchito ya michere ya chiwindi.
Kuphatikiza apo, kuvulaza komwe kumatha kudziwonekera kumawoneka ngati mitundu yosiyanasiyana ya ziwalo zam'malingaliro (masomphenya, kukoma).
Mankhwala Osakanikirana
Ngati wodwala amatenga mankhwala ena nthawi yomweyo, ayenera kudziwitsa a dokotala ake za izi. Kubisa zofunikira zoterezi kumabweretsa zotsatira zoyipa.
Zotsatira zamankhwala osiyanasiyana pakukhudzana ndi Diabetesalong ndizosiyana: nthawi zina zimathandizira mphamvu ya hypoglycemic, mwa ena, m'malo mwake, imachepa.
Kugwiritsa ntchito miconazole, phenylbutazone ndi ethanol kumathandizira kukulitsa dziko la hypoglycemic wodwala wodwala matenda a shuga. Ndipo danazol, chlorpromazine, GCS, terbutaline, ritodrine ndi salbutamol zimayambitsa kufooketsa mphamvu ya shuga yotsitsa shuga. Kuphatikiza apo, kugwiritsa ntchito Diabetesolong ndi anticoagulants kuyenera kuphatikizidwa mosamala.
Ndi kupanga hypoglycemia mofatsa kapena moyenera, wodwalayo akazindikira, ayenera kupatsidwa mankhwala okhala ndi shuga ndi chakudya (chidutswa cha shuga, chokoleti, msuzi wa zipatso wokoma). Kenako adzafunsira kwa dokotala pazamankhwala osintha kapena kusintha kwa mankhwala.
Woopsa wa hypoglycemic state, pomwe wodwalayo sakomoka ndipo ali ndi kukokana, kuchipatala chofunikira ndikofunikira. Zikatero, adotolo amamuuza wodwalayo njira yothetsera shuga (20-40%). Pambuyo pozindikira, amapatsidwa chakudya chomwe chimakhala ndi chakudya. Pambuyo pazachilengedwe, odwala matenda ashuga amayang'aniridwa ndi madokotala pafupifupi masiku awiri. Kenako dotolo amathetsa vuto la kupitilirabe mankhwala ndi hypoglycemic.
Dziwani kuti njira ya dialysis yamitundu yoopsa ya hypoglycemia siyothandiza, chifukwa gliclazide imangiriza mapuloteni m'madzi a m'magazi.
Mtengo, ndemanga ndi fanizo
Popeza mankhwalawa amagulitsidwa kokha ngati amupatsa mankhwala, wodwala matenda ashuga sangadzichiritse, pakuyamba, pezani thandizo kwa dokotala. Mankhwalawa amagulidwa onse muchipatala chokhazikika komanso pa intaneti.
Diabetesalong ili ndi mtengo wokwanira. Mwachitsanzo, mtengo wa kulongedza mapiritsi 30 mg (zidutswa 60) umachokera ku 98 mpaka 127 ma ruble aku Russia.
Ponena za malingaliro a ogula ndi madotolo, onse, aliyense ali wokondwa ndi mankhwalawa. Pogwiritsa ntchito Diabetesalong, ndemanga imati ndi mankhwala othandizadi pochiza matenda a shuga a 2. Chifukwa cha ndemanga za odwala ambiri omwe amagwiritsa ntchito mankhwalawa, zabwino zotsatirazi zitha kuunikiridwa:
- kutsika kosalala kwa shuga;
- kulumikizana kwabwino ndi mankhwala ena;
- mtengo wotsika mtengo wa mankhwala;
- kuwonda pakugwiritsa ntchito mapiritsi.
Komabe, munthawi ya chithandizo ndi mankhwalawa, odwala ambiri sanakonde kufunika kowunikira kuchuluka kwa shuga m'magazi awo. Koma ngati izi sizikuwopseza ena, ndiye kuti Diabetesalong ndi njira yabwino yokhazikitsira kuchuluka kwa glycemia. Kuphatikiza apo, kupitiliza kwake ntchito kumachepetsa kufunika kwa kuwonjezereka kwa shuga.
Ngati mankhwalawa amachititsa wodwala kusintha kosiyanasiyana kapena ngati wapangika, dokotala amamufotokozera. Njira zofananira ndizomwe zimakhala ndi magawo osiyanasiyana, koma zimathandizanso chimodzimodzi. Izi ndi monga: Amaryl, Glemaz, Glimepiride, Glyurenorm ndi mankhwala ena.
Komanso, adokotala amatha kuyang'ana pa kusankha kwa mankhwala ofanana, ndiye kuti, wothandizira yemwe ali ndi chinthu chimodzi chogwira ntchito. Kusiyanaku kumakhalapo pamaso pa okopa, mwachitsanzo, Diabeteson MV, Glidiab, Gliclada.
Diabetesalong ndi mankhwala abwino kwambiri ochepetsa shuga omwe amachepetsa shuga. Ndi kugwiritsa ntchito moyenera, wodwalayo amatha kukhazikika pamlingo wa glycemia komanso kupewa zovuta zovuta, makamaka mtima za mtima.
Ngati pazifukwa zina mankhwalawo sioyenera, mitundu yonse ya mitundu ingathe kuibwezeretsa. Chofunika kwambiri ndikulankhulana ndi dokotala ndikutsatira malangizo onse omwe aperekedwa.
