Acarbose ndi gawo limodzi mwa gulu la mankhwala ochepetsa matenda a shuga omwe amagwiritsidwa ntchito mwachangu kuchiza matenda amtundu wa 2 ndi matenda ashuga a 2.
Njira zozikidwa pachinthuchi zimakhala ndi katundu wa hypoglycemic, komanso zimakupatsani mwayi kuti muchepetse shuga kuti muzitha kugaya shuga. Mankhwalawa ndi ufa woyera, womwe umasungunuka mosavuta m'madzi.
Mankhwalawa ndi oyenera kwa odwala omwe akuwonetseredwa kwa matupi awo sagwirizana ndi insulin. Chimodzi mwamaubwino ake ndikuti mankhwalawo alibe zama carcinogenic ndi mutagenic.
Chuma chofunikira kwambiri pa mankhwala
- amathandizira kuchepetsa kuyamwa kwa mafuta m'matumbo;
- zimakhudza kusowa kwa hyperglycemia mukatha kudya;
- samatsogolera ku hypoglycemia;
- neutralates kuthekera kwa insulin kuchuluka;
- amathandiza kuchepetsa kunenepa kwambiri molumikizana ndi zakudya;
- amachepetsa chilala.
Mankhwala nthawi zambiri amagwiritsidwa ntchito kuti athetse zotsatirazi mawonetsedwe ndi mawonekedwe:
- Matenda a shuga osagwirizana ndi insulin.
- Type 1 shuga mellitus (chifukwa cha mankhwalawa, ndizotheka kuchepetsa kuchuluka kwa insulin yoyendetsedwa).
- Ndi chitukuko cha kagayidwe kachakudya kagayidwe kachakudya kapena kukana kwa mahomoni, insulin.
- Pa chisanadze matenda a shuga wodwala.
- Ngati zolakwika mu glucose kulolerana zimawonedwa.
- Ngati lactic acidosis kapena matenda ashuga atakula.
Kuphatikiza apo, Acarbose imagwiritsidwa ntchito pazovuta za metabolic, komanso kunenepa kwambiri.
Malangizo ogwiritsira ntchito mankhwalawa
Kwa Acarbose, malangizo omwe angagwiritsidwe ntchito amapereka zambiri zokhudzana ndi mphamvu ya mankhwalawa.
Musanagwiritse ntchito, muyenera kuwerengera mosamalitsa Mlingo woyenera ndi zovuta zina.
Mankhwalawa amaperekedwa kuchokera ku malo ogulitsa mankhwala pokhapokha ngati pali mankhwala kuchokera kwa dokotala. Nthawi yomweyo, mtengo wamapiritsi umapezeka m'magulu onse a anthu.
Mlingo wovomerezeka wa mankhwalawa umawerengedwa potengera thupi la wodwalayo. Pankhaniyi, gawo limodzi loyambirira m'magawo oyamba a chithandizo sayenera kupitirira milligram makumi awiri ndi zisanu. Mapiritsi ayenera kumwedwa katatu patsiku musanadye kapena panthawi ya chakudya chachikulu.
Ngati mulingo womwe suwonetsedwa sakubweretsa zabwino, mogwirizana ndi adokotala, atha kuwonjezeredwa mpaka kupitirira mamiligalamu mazana asanu ndi limodzi patsiku. Katswiri wa zamankhwala amadzisankhira payekhapayekha dokotalayo malinga ndi momwe wodwalayo alili ndi chithunzi chake chonse.
Sitikulimbikitsidwa kuwonjezera kuchuluka kwa okalamba, komanso omwe ali ndi vuto lachiwindi.
Mankhwalawa amayamba kugwira ntchito patatha ola limodzi atatha kumwa. Zochita zake zimatha kwa maola awiri. Ngati mankhwalawa adaphonya, palibe chifukwa chowonjezerera mulingo wotsatira. Acarose amaphatikiza bwino ndi sulfonylureas, zotumphukira za metformin kapena jakisoni wa insulin.
Njira ya mankhwala ndi mankhwala ayenera limodzi ndi kuvomerezedwa zakudya. Kupanda kutero, kudzimbidwa kumatha kuchitika.
Ntchito yolemba piritsi iyenera kusungidwa kutentha, kupewa dzuwa.
Mtengo wa mankhwala umasiyana ndi ma ruble 350 mpaka 500 phukusi lililonse (mapiritsi 30 okhala ndi mulingo wa 50 mg).
Zotsatira zoyipa mukamamwa mankhwalawa
Atsikana ndi amayi oyembekezera panthawi yoyembekezera amaletsedwa kumwa mankhwalawa, chifukwa zovuta zosiyanasiyana zomwe zimachitika mwa mwana wosabadwayo zimachitika.
Ndi kufunikira kwakanthawi kwamankhwala, mkazi ayenera kusiya kuyamwitsa. Kuphatikiza apo, ana osakwana zaka khumi ndi zisanu ali pachiwopsezo.
Sizoletsedwa kumwa mankhwalawo popanda kuikidwa ndi dokotala. Milandu yayikulu ikuphatikiza:
- pamaso pa mavuto ndi yachibadwa ntchito chiwindi, makamaka matenda enaake;
- ngati zotupa njira akuwonekera mu ziwalo zam'mimba thirakiti pachimake ndi matenda mawonekedwe;
- ulcerative colitis ndi matumbo kutsekeka, kuchuluka kwa mpweya;
- tsankho kapena hypersensitivity ku chimodzi kapena zingapo za mankhwala;
- pa chitukuko cha matenda osiyanasiyana a impso;
- ndi chiwonetsero cha matenda opatsirana, pakhungu kapena pambuyo povulala;
- ndi chiwonetsero cha matenda ashuga ketoacidosis;
- pambuyo pa opaleshoni;
- ngati pali hernias wamkulu.
Kuphatikiza apo, pali milandu ya bongo. Izi zitha kudziwoneka ngati:
- kuchuluka kwaulemu;
- kutsegula m'mimba.
Pofuna kuchepetsa zomwe zili pamwambapa chifukwa cha mankhwala osokoneza bongo, zakudya zopatsa mphamvu zamagulu ambiri zimayenera kupewedwa.
Munthawi ya kuyamwa kwa mankhwalawa, mavuto osiyanasiyana komanso zoyipa zimachitika. Izi zikuphatikiza:
- Kukula kwa thrombocytopenia ndi erythema.
- Mavuto ndi khungu - zotupa zosiyanasiyana ndi redness, rubella.
- Kusanza ndi kusanza.
- Mavuto ndi magwiridwe antchito a ziwalo zam'mimba;
- Kuchulukirachulukira, kutsekula m'mimba, kutsekeka kwathunthu kapena pang'ono kwamatumbo;
- Ululu pamimba.
Ngati mavuto aliwonse amachitika, ndikofunikira kukambirana ndi dotolo kuti mwina mungamwe mankhwalawo.
Malinga ndi kuwunika kwa wodwala, mankhwalawa amalekeredwa mosavuta ngati malingaliro ndi chisamaliro chofotokozedwa mogwirizana ndi malangizo ogwiritsira ntchito mapiritsi amawonekera.
Mankhwala omwe amalowa m'malo mwa Acarbose
Ngati ndi kotheka, dokotala yemwe amapezekapo akhoza kusintha mankhwala ena ndi omwewo kapena mawonekedwe omwewo. Imodzi mwazofala kwambiri masiku ano imadziwika kuti Glyukobay. Awa ndi mankhwala opangidwa ku Germany, chinthu chachikulu chomwe ali ngati acarbose.
Pafupipafupi, Glyukobay angagulidwe kuzipatala zamzindawo zama ruble 380. Kuphatikiza apo, mtengo wake umasiyanasiyana ma ruble a 360 mpaka 500 phukusi lililonse, kutengera kuchuluka kwa mapiritsi ndi kipimo. Glucobai imagawiridwa pokhapokha ngati pali mankhwala kuchokera kwa katswiri wazachipatala.
M'mapangidwe awo, mapiritsi ndi analogue yathunthu ya Acarbose. Nthawi zambiri, Glucobai amagwiritsidwa ntchito pofuna kuchiza matenda a shuga 2 mellitus molumikizana ndi chithandizo chamankhwala.
Njira zazikulu zamankhwala zimapangidwira ndi zovuta za thupi pa wodwala. Glucobay imakhazikitsidwa bwino pamsika, chifukwa ndi imodzi mwamankhwala othandiza kwambiri.
Kuphatikiza apo, mankhwala otsatirawa akuphatikizidwa ndi kuchuluka kwa mankhwala a analog:
- Siofor.
- Alumina
- Sadifit.
Siofor ndi piritsi lomwe limagwiritsidwa ntchito pochiza matenda osokoneza bongo omwe amadalira shuga. Mapiritsi amapezeka mosiyanasiyana, kutengera kuopsa kwa matendawa. Mtengo wapakati mumasitolo amzinda ndi ma ruble 300. Tiyenera kudziwa kuti kuchuluka kwa mankhwala omwe amapezeka piritsi limodzi, kukwera mtengo kwa mankhwalawo.
Alumina - mapiritsi okhala ndi mankhwala acarbose. Itha kupangidwa mu Mlingo wa 50 kapena 100 mg wa chinthu chachikulu. Ndi mankhwala apakamwa omwe amakhala ndi zinthu zotsitsa shuga. Nthawi zambiri amatchulidwa kuwonjezera mphamvu ya zakudya. Alumina amapangidwa ku Turkey.
Zambiri pazokhudzana ndi zamankhwala a Acarbose zimawonetsedwa mu kanema munkhaniyi.
