Nicotinic acid ndi gulu lomwe limakhala m'gulu lokonzekera Vitamini. Ili ndi zida zambiri zofunikira mthupi la munthu. Itha kugwira ntchito ngati vasodilator, kutsitsa magazi komanso kusintha kupezeka kwa mpweya ndi michere minofu.
Pankhani imeneyi, chida ichi nthawi zambiri chimaperekedwa pochiza matenda osiyanasiyana.
Nicotinic acid kapena vitamini B3, monga lamulo, amagwiritsidwa ntchito polimbikitsa njira yamagazi, komanso njira zosinthira mapuloteni, mafuta, chakudya ndi amino acid m'thupi la munthu. Kuphatikiza apo, mankhwalawa amathandizira kuyambitsa ndi kukonza magwiridwe antchito a ubongo.
Posachedwa, kwakhala kofala kupeza njira yogwiritsira ntchito mankhwala pofuna kupewa matenda monga:
- matenda osiyanasiyana a mtima;
- zovuta zamagazi kumunsi;
- kukhalapo kwa thrombophlebitis;
- venous kusowa.
Komanso nicotinic acid amagwiritsidwa ntchito kuchepetsa kuchuluka kwa cholesterol, triglycerides ndi lipoprotein wotsika kwambiri m'magazi.
Kufotokozera ndi kapangidwe kake ka mankhwala
Monga tanena kale, vitamini B3 ndi mtundu wa vitamini womwe umasungunuka m'madzi. Mankhwalawa amagwira ntchito monga oxidative komanso kuchepetsa zomwe zimachitika pafupifupi m'thupi lonse. Kuphatikiza apo, chinthucho chimakhutitsa maselo amthupi ndi mpweya. Chifukwa chake, titha kunena kuti iyi ndi chida chofunikira kwambiri pakugwirira ntchito moyenera ndi ntchito zofunika mu khungu lililonse komanso chamoyo chonse. Popanda chinthu ichi, thupi silingagwire ntchito moyenera.
Nicotinic acid kapena Vitamini PP imapezeka m'mitundu iwiri yayikulu, mwachindunji acid ndi nicotinomide. Izi ndi zinthu ziwiri zomwe zimagwira ntchito, kupezeka kwake komwe kumagwiritsa ntchito mankhwala, kumalumikizana ndi gulu la nicotinic acid.
Mankhwala opangidwa ndi nikotini amapezeka mu mawonekedwe a mapiritsi ndi yankho la jakisoni. Piritsi lililonse limakhala ndi nicotinic acid monga chinthu chachikulu chogwira ntchito. Zosakaniza zina zogwira ntchito ndi stearic acid ndi glucose. Mutha kugula malonda pamtengo wa ma ruble 15 mpaka 35 pama mapiritsi 10 kapena 50 pa paketi iliyonse. Za mtundu wachiwiri wa kumasulidwa, ndi chinthu chofanana, sodium bicarbonate ndi madzi osungunuka ndiwothandiza. Mbale umodzi uli ndi 1 ml kapena 10 mg. Phukusili lili ndi ma 1020 ampoules, ndipo mutha kugula malonda pamtengo wa 20-70 rubles.
Chizindikiro chachikulu cha kugwiritsidwa ntchito kwa asidi ndi kuchepa kwa vitamini B3. Kuphatikiza apo, kugwiritsidwa ntchito kwake kumalimbikitsidwa kusintha magwiridwe antchito amitsempha yamagazi. Kugwiritsa ntchito mankhwalawa kumalimbikitsidwanso ngati kuli kofunikira kukhazikitsa kuvomerezeka kwa makoma amitsempha yamagazi. Chifukwa cha izi, kutupa kwa minofu kumatha kuchepetsedwa. Kuphatikiza apo, nicotinic acid imathandizira kukonza nayitrogeni-carbohydrate metabolism ndi microcirculation m'thupi. Pambuyo popita mankhwalawa, mawonekedwe a minyewa, kuphatikizapo yaying'ono, komanso ziwiya zaubongo, imasintha. Vitamini PP ikalowa m'thupi, imasinthidwa kukhala nicotinamide, yomwe imakumana ndi coenzymes omwe amayang'anira hydrogen.
Chithandizo chogwira ntchito cha mankhwalawa chimadziunjikira m'chiwindi ndi adipose, ndipo zochulukazo zimatsitsidwa ndi impso.
Mu milandu iti yomwe ikuyenera kutengedwa?
Niacin ndi chinthu chapadera pakuchita kwawo. Imatenga gawo pafupi zochita zonse za metabolic mthupi. Kugwiritsa ntchito mankhwalawa, mutha kusintha chiwindi, m'mimba, kuchepetsa shuga komanso kukhala ndi zotsatira zabwino pa mabala ndi zilonda zam'mimba. Nicotinic acid ndi wofunika makamaka ku boma la mitsempha yamagazi.
Chifukwa chachikulu chotengera nicotinic acid ndikuthekera kwake kukulitsa mitsempha yamagazi, kuchepetsa magazi m'magazi ndikuwonjezera madzi. Kukwezedwa kwa cholesterol, atherosulinosis, ndi matenda ena ambiri okhudzana ndi kupuwala kwamitsempha yamagetsi kumawonetsa kugwiritsa ntchito mankhwala a vasodilator ngati mankhwala komanso kupewa.
Piritsi ya nicotinic acid imathandiza ngati wodwalayo ali ndi matenda oopsa, atherosulinosis yamitsempha yama mtima, angina pectoris kapena kuchuluka kwa magazi, komanso mitsempha ya varicose ndi phlebitis. Chofunikira chachikulu cha mankhwalawa chimathandizira kuyeretsa kwamitsempha yamagazi ndikumachepetsa milomo ya lipoprotein, cholesterol yotsika komanso triglyceride, zomwe zimapangitsa kuti magazi azitsekeka. Ichi ndi prophylactic yabwino yotsutsana ndi mapangidwe amwazi ndi malo amitsempha yamagazi m'magazi, zomwe pambuyo pake zimatha kubweretsa zovuta zina, kuphatikizapo stroke, kugunda kwa mtima, kuthamanga kwa magazi komanso kuchepa kwa magazi.
Niacin imatha kukhala ndi zotsatira zopindulitsa pakuthamanga kwa magazi komanso ku thupi lonse. Chifukwa cha izi, nthawi zambiri zimatha kukumana ndi ndemanga yabwino mutamwa mankhwalawa. Osangokhala bwino kwa wodwalayo kumangowonjezereka, komanso ntchito za ubongo makamaka. Kumbukirani kuti ndi dokotala yekha amene angatchule kuchuluka kwa mankhwala omwe amafunikira kumwa. Mwachitsanzo, ngati munthu ali ndi matenda a ischemic, tikulimbikitsidwa kugwiritsa ntchito mavitamini PP mwa jakisoni m'mitsempha mu 1 ml.
Niacin akuwonetsedwa kuti agwiritsidwe ntchito pa matenda a pathologies monga:
- Cerebral hemorrhage wa ischemic chikhalidwe.
- Kuperewera kwa Vitamini.
- Osteochondrosis.
- Zosokoneza ubongo.
- Matenda a ziwiya zamiyendo.
- Atherosulinotic pathologies.
- Kupezeka kwa tinnitus.
Kuphatikiza apo, kumwa mankhwalawa tikulimbikitsidwa ngati pali zilonda zam'mimba.
Contraindication ndi zoyipa
Monga chithandizo china chilichonse chamankhwala, nicotinic acid imakhala ndi mawonekedwe ake ndi contraindication kuti agwiritse ntchito, pomwe amasiyana malinga ndi mawonekedwe omwe mankhwalawo amasulidwa. Mwambiri, zopinga zomwe zimadziwika kwambiri ndimavuto a chiwindi, magazi, magazi a m'magazi, komanso kukhudzika kwa chidwi ndi gawo lalikulu.
Piritsi la mankhwalawa silikulimbikitsidwa kuti mugwiritse ntchito pachilonda, komanso kwa ana osakwana zaka 2. Kwa jekeseni wa mankhwalawa, kuphwanya kwakukulu ndiko kukhalapo kwodziwikiratu kwa matenda a m'mimba, matenda oopsa, matenda oopsa, gout, komanso msinkhu waung'ono.
Kuphatikiza pa ma contraindication, palinso zotsatira zoyipa, pakati pazomwe ndizambiri:
- redness la pakhungu pakumatha kuzindikira komanso kumva kugunda;
- hypotension;
- kwambiri secretion wa chapamimba madzi;
- kuthira magazi kumutu;
- mawonekedwe a urticaria ndi kuyabwa.
M'pofunika kuwunikira zotsatira zoyipa kuposa kuchuluka kwa vitamini B3, pomwe zina ndizambiri:
- Anorexia
- Mavuto a chiwindi, biliary pancreatitis.
- Kusanza, kusanza, komanso kupweteka m'mimba.
- Mavuto a chimbudzi.
- Paresthesia
- Arrhasmia.
- Kulekerera kwa shuga.
Ngati mulingo wambiri, munthu akhoza kudwala matenda a hyperglycemia.
Malangizo ogwiritsira ntchito mankhwalawa
Kuti muwonetsetsetsetse kwambiri pakugwiritsira ntchito mankhwalawa, ndikofunikira, choyamba, kutsatira mosamalitsa malangizo ogwiritsira ntchito. Pankhani ya jakisoni wovomerezeka, mulingo wake umatengera zomwe zikuwonetsa. Mwachitsanzo, ngati wodwala wadwala matenda a ischemic kapena pellagra, mankhwalawo amapakidwa pang'onopang'ono kudzera m'mitsempha. Kuchita ziwengo m'magazi kumaphatikizapo kugwiritsa ntchito mankhwalawa kamodzi kapena kawiri mu 50 mg kapena 100 mg m'mitsempha kapena minofu, motero. Maphunzirowa ali pafupifupi masiku 10-15.
Jakisoni wamkati amapangidwa kuchokera ku yankho la 1% mu 1 ml. Njira yothetsera vutoli imalowetsedwa m'mitsempha yambiri ya 1-5 ml, pomwe iyenera kuyamba kuchepetsedwa mu 5 ml ya saline yanyama. Nthawi zina, jakisoni amatha kupweteka, kutentha, kubwezeretsa malo a jakisoni, kapena kumva kutentha. Uku ndi kusintha kwachilendo kwa mankhwalawa. Chifukwa chake, simuyenera kuda nkhawa.
Mapiritsi amalimbikitsidwa kuti azigwiritsidwa ntchito mukatha kudya. Pazifukwa zodzitetezera, mulingo wa mankhwalawa umasiyana kuchokera ku 12,5 mpaka 25 mg kwa akuluakulu komanso kuyambira 5 mpaka 25 mg wa ana patsiku. Kukhalapo kwa matenda (mwachitsanzo, pellagra, chiyambi cha atherosulin, etc.) kumatanthauza kuwonjezeka kwa kugwiritsa ntchito mankhwalawa mpaka nthawi 2-4, ndipo kuchuluka kwa mankhwalawa ndi 100 mg kwa akuluakulu, 12,5-50 mg kwa ana. Kutalika kwa maphunzirowa ndi mwezi 1, ndikupuma pakati pamaphunziro.
Nthawi zina, kupitilira muyeso womwe ungafotokozeredwe kungayambitse kuchuluka kwa mankhwala osokoneza bongo komanso kupezeka kwa zotsatira zoyipa, zomwe zimawoneka ngati kuthamanga kwa magazi kumtunda wam'mimba, kukhumudwa m'mimba ndi mawonekedwe a kuyabwa. Zikachitika kuti chimodzi mwazizindikirozi, ndikofunikira kusiya chithandizo.
Kuphatikiza apo, musanamwe nicotinic acid, ndikofunikira kuti mudziwe zolakwika zomwe mungagwiritse ntchito, monga kupezeka kwa mawonekedwe oopsa a matenda oopsa komanso atherosclerosis, komanso kumva kwambiri mbali zazikulu za mankhwalawo.
Osagwiritsa ntchito mankhwalawa kwa nthawi yayitali, chifukwa izi zingayambitse chiwindi chamafuta.
Nicotinic acid wothamanga magazi
Kuchulukitsa kwa Arterial ndi chizindikiro china chomwe muyenera kutsatira musanayambe kumwa mankhwalawa.
Musanagwiritse ntchito mankhwala a nicotinic acid kuti muthandizire odwala, muyenera kufunsa dokotala za nkhaniyi.
Kuphatikiza apo, phukusi lililonse lili ndi mawu ofotokozera, omwe amafunikiranso kuwerengedwa.
Ili ndi malangizo apadera omwera mankhwalawa, omwe ndi:
- Niacin angagwiritsidwe ntchito pa nthawi yoyembekezera komanso mkaka wa m'mawere pokhapokha mlingo wochepa;
- Kudutsa njira ya mankhwalawa kumaphatikizapo kuwunika chiwindi chonse;
- Vitamini B3 iyenera kugwiritsidwa ntchito mosamala vuto la hyperacid gastritis ndi zilonda zam'mimba, komanso hepatitis, cirrhosis kapena matenda a shuga;
- odwala matenda ashuga sangathe kumwa mankhwalawa kuti achulukitse dyslipidemia;
- magawo oyamba kumwa mankhwalawa, ndikofunikira kuyang'anira kuchuluka kwa mafuta, shuga ndi uric acid m'thupi;
- Kugwiritsa ntchito asidi nthawi yayitali kungayambitse kuchepa kwa vitamini C mthupi.
Niacin ndi chinthu chopindulitsa kwambiri kwa thupi la munthu aliyense. Zimathandizira kuchepa kwa mafuta m'thupi, kuchotsa poizoni ndikufulumizitsa njira zama metabolic. Kuphatikiza apo, ndi thandizo lake ndikotheka kuchepetsa njira zotupa, onetsetsani kuti vasodilation ndi kuwonda kwa magazi, komwe kumachepetsa kwambiri matenda a atherosulinotic ndi matenda ena ophatikizana.
Katswiri azilankhula za nicotinic acid yemwe ali mu vidiyoyi.
