Protafan NM Penfill ndi othandizira omwe amathandiza pochiza matenda osokoneza bongo. Mankhwalawa, akamagwiritsidwa ntchito moyenera, amakulolani kutsata kuchuluka kwa shuga m'magazi popanda kuvulaza thanzi la wodwalayo.
Dzinalo Losayenerana
Insulin yamunthu.
ATX
A.10.A.C - insulins ndi mawonekedwe awo ofanana ndi nthawi yayitali yochitapo kanthu.
Kutulutsa mafomu ndi kapangidwe kake
Kuyimitsidwa kwa subcutaneous makonzedwe a 100 IU ml amapezeka mu mawonekedwe a: botolo (10 ml), cartridge (3 ml).
The 1 ml ya mankhwala muli:
- Zosakaniza: yogwira insulin-isophan 100 IU (3.5 mg).
- Zothandiza: glycerol (16 mg), zinc chloride (33 μg), phenol (0.65 mg), sodium hydrogen phosphate dihydrate (2.4 mg), protamine sulfate (0.35 mg), sodium hydroxide (0,4 mg ), metacresol (1.5 mg), madzi a jakisoni (1 ml).
Kuyimitsidwa kwa subcutaneous makonzedwe a 100 IU ml amapezeka mu mawonekedwe a: botolo (10 ml), cartridge (3 ml).
Zotsatira za pharmacological
Zimatanthauzira othandizira a hypoglycemic okhala ndi nthawi yayitali yochitapo kanthu. Zimapangidwa ndi ukadaulo wama DNA womwe umagwiritsa ntchito Saccharomyces cerevisiae. Imakhudzana ndi ma membrane receptors, ndikupanga insulini-receptor zovuta zomwe zimapangitsa kuti kapangidwe kake ka ma enzymes akhale ndi moyo (hexokinases, glycogen synthetases).
Mankhwalawa amathandizira kuyendetsa mapuloteni kudzera m'maselo a thupi. Zotsatira zake, kukweza kwa glucose kumapangidwira bwino, lipo- ndi glycogeneis imalimbikitsidwa, ndipo kupanga shuga kwa chiwindi kumachepetsedwa. Kuphatikiza apo, mapuloteni amaphatikizidwa.
Pharmacokinetics
Kugwiritsa ntchito bwino kwa mankhwalawa komanso kuthamanga kwa kukhuthala kwake kumatsimikiziridwa ndi kuchuluka, komwe jakisoni, njira ya jakisoni (subcutaneous, intramuscular), zomwe zili mu insulin. Zokwanira zomwe zimakhala m'magazi zimafikiridwa pambuyo pa maola 3-16 pambuyo pobayira jekeseni.
Zizindikiro zogwiritsidwa ntchito
Matenda a shuga
Protafan NM Penfill ndi othandizira omwe amathandiza pochiza matenda osokoneza bongo.
Contraindication
Ndi hypersensitivity kwa insulin ya anthu kapena zinthu zomwe zimapanga mankhwala, hypoglycemia ndi yoletsedwa.
Ndi chisamaliro
Mosamala zotchulidwa vuto la kusasunga zakudya zamasiku onse kapena kuchita zolimbitsa thupi kwambiri, monga hypoglycemia ikhoza kuchitika. Kusamala ndikofunikanso pakusintha mtundu wina wa insulin kupita ku wina.
Momwe mungatenge Protafan NM Penfill?
Chitani jakisoni wamkati kapena subcutaneous. Mlingo wake umasankhidwa potengera mawonekedwe ndi matendawo. Kuchuluka kwovomerezeka kwa insulin kumasiyana pakati pa 0.3-1 IU / kg / tsiku.
Lowetsani insulin pogwiritsa ntchito cholembera. Anthu omwe ali ndi vuto la insulin amakumana ndi kuchuluka kwa insulini (panthawi ya chitukuko cha kugonana, kulemera kwambiri kwa thupi), motero amapatsidwa mlingo waukulu.
Kuti muchepetse chiopsezo cha lipodystrophy, ndikofunikira kusintha malo a mankhwala. Kuyimitsidwa, molingana ndi malangizo, ndizoletsedwa kulowa intraral.
Ndi matenda ashuga
Protafan imagwiritsidwa ntchito pa mtundu uliwonse wa matenda ashuga. Njira yochizira imayamba ndi matenda a shuga 1. Mankhwala 2 amalembedwa ngati palibe zotsatira kuchokera ku mankhwala a sulfonylurea, panthawi yomwe ali ndi pakati, panthawi yomwe akuchitidwa opaleshoni, komanso ma pathologies omwe amaphatikizana ndi zovuta za matenda ashuga.
Zotsatira zoyipa za Protafan NI Penfill
Zochitika zoyipa zomwe zimawonetsedwa panthawi ya odwala zimachitika chifukwa cha mankhwala osokoneza bongo ndipo zimagwirizanitsidwa ndi pharmacological ya mankhwala. Mwa zina zomwe zimachitika kawirikawiri, hypoglycemia imadziwika. Chimawonekera chifukwa chosagwirizana ndi mlingo wa insulin.
Mu hypoglycemia yayikulu, kusazindikira, kukhudzika, kusokonezeka kwa ubongo, ndipo nthawi zina kufa, ndizotheka. Nthawi zina, pali kuphwanya kwa kagayidwe kazakudya.
Mbali ya chitetezo chamthupi ndi yotheka: totupa, urticaria, thukuta, kuyabwa, kufupika, kusokonekera kwa mtima, kuchepa magazi, kusiya kudziwa.
Pa chitetezo cha mthupi, zotsatira zoyipa ndizotheka: zotupa, urticaria, kuyabwa.
Mchitidwe wamanjenje ulinso pachiwopsezo. Nthawi zina, zotumphukira neuropathy zimachitika.
Malangizo apadera
Mlingo wosankhidwa mosayenera kapena kuchotsedwa kwa mankhwalawa kumayambitsa hyperglycemia. Zizindikiro zoyambirira zimayamba kuonekera patatha maola ochepa kapena masiku. Ngati chithandizo sichiperekedwa nthawi, chiopsezo chokhala ndi matenda ashuga a ketoacidosis, omwe amakhudza kwambiri moyo wa munthu, amawonjezeka.
Ndi ma concomitant pathologies omwe amawonetsedwa ndi kutentha kapena matenda opatsirana, kufunikira kwa insulin mwa odwala kumawonjezeka. Ngati ndi kotheka, sinthani mulingo womwe ungasinthidwe panthawi ya jakisoni woyamba kapena ndi chithandizo china.
Gwiritsani ntchito mu ukalamba
Odwala mpaka zaka 65 sakhala ndi zoletsa kumwa mankhwalawa. Pofika msinkhu uno, odwala ayenera kuyang'aniridwa ndi adokotala ndikuwunika zinthu zokhudzana ndi izi.
Kulembera Protafan NM Penfill kwa ana
Itha kugwiritsidwa ntchito kwa ana ochepera zaka 18. Mlingo wakhazikitsidwa payekha pamaziko a kafukufukuyu. Nthawi zambiri amagwiritsidwa ntchito mu mawonekedwe a madzi.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Kugwiritsidwa ntchito pa nthawi yoyembekezera, monga samadutsa placenta. Ngati matenda a shuga sagwiritsidwa ntchito nthawi yakhazikitsidwa, chiopsezo kwa mwana wosabadwayo chikukula.
Hypoglycemia yovuta imachitika ndi njira yosankhidwa yosasankhidwa bwino, yomwe imawonjezera chiopsezo cha zolakwika mwa mwana ndikumuwopseza kuti adzafa ndi intrauterine. Mu trimester yoyamba, kufunika kwa insulin kumakhala kotsika, ndipo mu 2 ndi 3 kumawonjezeka. Pambuyo pobereka, kufunika kwa insulini kumakhala chimodzimodzi.
Mankhwalawa si owopsa poyamwitsa. Nthawi zina, kusintha kwa jekeseni kapena zakudya kumafunika.
Mankhwala ochulukirapo a Protafan NI Penfill
Mlingo wobweretsa mankhwala osokoneza bongo sunazindikiridwe. Kwa wodwala aliyense, polingalira za njira ya matendawa, pali mlingo waukulu, womwe umatsogolera ku mawonekedwe a hyperglycemia. Ndi hypoglycemia yofatsa, amatha kupirira nayo payekha pakudya zakudya zotsekemera ndi zakudya zokhala ndi chakudya chamagulu ambiri. Sizopweteka kukhala ndi maswiti pamanja, ma cookie, misuzi ya zipatso kapena chidutswa cha shuga.
Mitundu yayikulu (kusazindikira), yankho la glucose (40%) imalowetsedwa mu mtsempha, 0,5-1 mg wa glucagon pansi pa khungu kapena minofu. Munthu akakhala ndi chidwi, kuti apewe ngozi zomwe zingayambenso, amapatsa chakudya chamoto chambiri.
Kuchita ndi mankhwala ena
Mankhwala a Hypoglycemic amachulukitsa mphamvu ya insulin. Zoletsa za monoamine oxidase, carbonic anhydrase ndi angiotensin potembenuza enzyme, Bromocriptine, Pyridoxine, Fenfluramine, Theophylline, mankhwala okhala ndi ethanol, Cyclophosphamide imawonjezera insulin.
Kugwiritsa ntchito njira zakulera zam'mlomo, mahomoni a chithokomiro, Heparin, Phenytoin, Clonidine, Diazoxide, morphine ndi nikotini, glucocorticosteroids amachititsa kuti mankhwalawa afooke. Reserpine ndi salicylates, Lanreotide ndi Octreotide amatha kupititsa patsogolo ndikuchepetsa zomwe zimagwira pazomwe zimagwira.
Beta-blockers amabisa zisonyezo zoyambirira za hypoglycemia ndikuwonjezera kuyimitsidwa kwake kwina.
Kuyenderana ndi mowa
Mowa umakulitsa ndikuwonjezera mphamvu ya mankhwalawo.
Analogi
Mankhwala othandizira omwe ali ndi vuto lofananalo: Protamine-insulin mwadzidzidzi, Gensulin N, Humulin NPH, Insuman Bazag GT.
Kupita kwina mankhwala
Ndi mankhwala.
Kodi ndingagule popanda kulandira mankhwala?
Ayi.
Mtengo
Mtengo wa botolo la 10 ml ndi ma ruble 400-500, cartridge ndi 800- 900 rubles.
Zosungidwa zamankhwala
Mankhwalawa ayenera kusungidwa m'malo abwino komanso amdima pa kutentha kwa + 2 ... + 8 ° C (akhoza kuyikidwa mufiriji, koma osati mufiriji). Sichikhala ndi kuzizira. Katiriji amayenera kusungidwa mu paketi yake kuti atetezeke ku dzuwa.
Bokosi lotseguka limasungidwa pa 30 ° C kwa masiku osaposa 7. Osasunga mufiriji. Kuletsa ana kuti azilankhula.
Tsiku lotha ntchito
Zaka 2,5. Pambuyo tikulimbikitsidwa kutaya.
Wopanga
NOVO NORDISK, A / S, Denmark
Ndemanga
Svetlana, wazaka 32, Nizhny Novgorod: "Pa nthawi yoyembekezera ndimagwiritsa ntchito Levemir, koma hypoglycemia amawonetsedwa nthawi zonse. Dotolo yemwe adakhalapo adalimbikitsa kusintha majekeseni a Protafan NM Penfill.
Konstantin, wazaka 47, Voronezh: "Ndadwala matenda ashuga kwa zaka 10. Sindinathe kusankha mankhwalawa oyenera kukhala ndi shuga wamagazi nthawi zonse. Ndinagula jakisoni wa Protafan NM Penfill miyezi isanu ndi umodzi yapitayo ndipo ndikusangalala ndi zotulukapo zake zonse. zovuta ndi zovuta zomwe zimawoneka kale sizimadzipatsanso chidwi. Mtengo wake ndi wokwanira. "
Valeria, wazaka 25, ku St. Petersburg: "Ndakhala ndikudwala matenda ashuga kuyambira ndili mwana. Ndinayesa mankhwala opitilira 7, ndipo palibe amene adakhutira kwathunthu. Mankhwala omaliza omwe ndidagula pazomwe adokotala anali atandiuza anali a Protafan NM Penfill. Mpaka chomaliza, ndinakaikira. Sindikukhulupirira kuti zinthu zitha kusintha. Koma ndidawona kuti kuyambika kwa hypoglycemia sikunadwalanso, thanzi langa linali labwino. Ndimagula m'mabotolo. Mankhwala ndi osavuta kugwiritsa ntchito komanso osakwera mtengo. "
