Kuphwanya mafuta kagayidwe koyambirira kumatha kupezeka ndikuwunika magazi. Tsoka ilo, mawonekedwe a madandaulo abwinobwino ndiwowopsa kwa thupi ndipo ali ndi phindu losavomerezeka.
Atherosclerosis ndi matenda ofala kwambiri omwe amachitika ndi vuto la lipid m'thupi. Atherosulinosis imatsogolera pakati pama mtima onse. Izi, ndizomwe zimapangitsa kuti anthu azifa padziko lonse lapansi.
Chifukwa cha mapangidwe a maphunzirowa ndi kuuma kwa matendawa, kuyambira ali ndi zaka 25, ndikulimbikitsidwa kuti anthu onse azitha kuwunika matenda amtima.
Kuti muwone momwe metabolism yamafuta alili, kuwunika kumachitika polemba mbiri ya lipid yomwe imawonetsa kuchuluka kwa cholesterol, triglycerides (TAG), ndi lipoproteins yamafinya osiyanasiyana. Ngakhale ndikusintha kochepa pakayezetsa magazi, mawu omaliza ayenera kutsimikizika ndipo, osintha moyo wanu.
Zoyambitsa kuchuluka kwa triglyceride
Kuwonjezeka kwa kuchuluka kwa TAG kumawonetsa kuphwanya kwa lipid metabolism. Malinga ndi kapangidwe ka mankhwala, ndi organic ether. Triglycerides amalowa mthupi ndi chakudya. Kuphatikiza apo, izi zimapangidwa m'maselo a chiwindi kuchokera glycogen.
Triglycerides amapangidwanso kuchokera kumafuta amthupi mwa anthu onenepa kwambiri. Mosiyana ndi cholesterol, triglycerides samayikidwa pamakoma a endothelium. Mlingo wa TAG mu seramu sayenera kupitilira theka ndi mmol / l. Mfundo zapamwamba zimapatsa mpata kuchititsa maphunziro owonjezera kuti adziwe zomwe zimayambitsa kusokonekera kwa metabolic yama mafuta oyambira.
Kuwongolera kwa kuchuluka kwa TAG kumachitika nthawi yomweyo ndi chithandizo cha matenda oyambitsidwa.
Etiology yowonjezera TAG m'magazi:
- aimpso kuwonongeka;
- chithokomiro chithokomiro;
- kudya kwambiri;
- zakudya zosayenera zomwe zili ndi zakudya zopanda pake;
- bulimia
- kumwa pafupipafupi;
- kunenepa kwambiri komanso kunenepa kwambiri;
- kapamba
- IHD ndi mitundu ina ya atherosulinosis;
- iatrogenic genesis;
- purine kagayidwe;
- matenda a shuga;
- thalassemia (cholowa m'magazi);
- kusowa zolimbitsa thupi;
- zaka odwala.
Kuwonjezeka kwa ndende ya TAG kumawonetsa kuphwanya kwa kagayidwe ka mafuta ambiri. Chizindikirochi sichimangodalira kulemera ndi zakudya za wodwalayo.
Kuchiza kuyenera kuchitika kokha moyang'aniridwa ndi dokotala.
Mawonekedwe akusintha pamlingo wa triglycerides mwa amayi ndi abambo
Pali zinthu zina zomwe zimapangitsa kuti pakhale vuto la lipid m'magulu osiyanasiyana. Ndikofunikira kuti azimayi azindikire kuti njira yachilengedwe ya pathological mu nthawi yake ndikuyamba chithandizo. Choyamba, adokotala ayenera kudziwa ngati wodwala wake amamwa mankhwala a mahomoni, mwachitsanzo, kuphatikiza kwa pakamwa ndi ena. Ambiri aiwo amatha kuwonjezera TAG komanso kusowa kwa magazi. Kuphatikiza kwapakati pakamwa, ma progestin amatha kusokoneza kayendedwe ka msambo kumayambiriro kwa makonzedwe, potero kumayambitsa kuphwanya kagayidwe kachakudya mthupi. Nthawi zina, kusintha kwa mtundu wa TAG ndichizindikiro cha kusintha kwa mankhwalawa komanso kuletsedwa kwathunthu. Komanso kumwa mankhwala okodzetsa kumawonjezera TAG komanso kachulukidwe ka magazi.
Inde, kunenepa kwambiri komanso kunenepa kwambiri ndikofunikira. Poterepa, kulumikizana mwamphamvu komanso mwachindunji kumawonedwa. Kuchuluka kwa kunenepa kwambiri, kumakulanso kuchuluka kwa TAG.
M'miyezi yoyamba ya kubereka, zimawonjezeranso khansa. Vutoli limafotokozedwa ndi kufunidwa kwakukulu kwa khanda lomwe limakula la michere. Izi sizitengera chithandizo cha mankhwala, koma zikuwonetsa kufunikira kuyang'anira bwino mtundu wa zakudya.
Chiyeso chovomerezeka chachikulu cha TAG m'magazi a amuna ndichokwera pang'ono kuposa cha akazi. The etiology yowonjezera izi mu seramu ya magazi ya amuna imayimiridwa ndi njira yolakwika komanso chikhalidwe cha zakudya. Zomwe zimayambitsa ndizo:
- Zakudya zopatsa thanzi zopatsa thanzi zambiri zomwe zimakhala ndi mafuta komanso chakudya chamafuta ambiri.
- Mowa.
- Khalidwe labwino.
- Kutsutsa pang'ono komanso kukhudzika kwakukuru mu chilengedwe.
- Kumwa magulu ena a mankhwala. Makamaka, mankhwala a cytotoxic (oyenera kwa khansa ndi odwala rheumatological).
- Kugwiritsa ntchito zakudya zamagulu, mahomoni a androgen ndi mahomoni a steroid.
Pankhani yachilendo chifukwa cha kuperewera kwa kagayidwe kachakudya, kukana mankhwala kumayambitsa kukonzekera mayeso.
Zosintha za mbiri ya lipid
Ngati triglycerides ndiyabwinobwino, ndipo cholesterol imakwezedwa, njira zowonjezereka ndizofunikira kuzindikira kutanthauzira kwa pathological process.
Nthawi zambiri kuphwanya kotereku kumatanthauza kukhalapo kwa njira ya atherosselotic m'matumbo.
Chipatala nthawi zambiri amakumana ndi kukula "koyenera" kwamitundu yonse ya mbiri ya lipid. Koma mwa odwala ena pamakhala dissonance yapadera: mulingo wazinthu zina ndiwabwinobwino, pomwe ena akukula.
Chomwe chimapangitsa izi
- kusintha kwadzidzidzi pakudya;
- chiwindi ndi kuwonda ntchito;
- zokhudza zonse rheumatological matenda;
- matenda kagayidwe kachakudya matenda, mwachitsanzo, matenda a shuga;
- Hyperfunction wa adrenal kotekisi;
- aakulu kapamba;
Mankhwala pazinthu zotere, ndikofunikira kugwiritsa ntchito mankhwala osakaniza. Muzochitika zonsezi, kusiyanitsa kwa triglycerides ndi cholesterol kungathe.
Wophwanya mbiri ya lipid, wodwala akhoza kukumana:
- Idiopathic amadumphira m'magazi.
- Kulekerera kwa shuga.
- Inachepetsa cholesterol ya HDL ndikuchulukitsa cholesterol ya LDL.
- Minofu kukana insulin.
- Kukula kwa magazi.
- Zizindikiro za thrombosis.
- Kuphwanya minofu ya trophic chifukwa cha hypoxia.
Makhalidwe onsewa amachititsa kuti wodwala azitsika pang'ono. Pankhani imeneyi, hypertriglyceridemia ndi chidziwitso cha chithandizo chamankhwala.
Njira zochizira hypertriglyceridemia
Ngati kuphwanya kwamafuta kagayidwe kamapezeka, ndikofunikira kuyamba chithandizo munthawi yake.
Kukwezedwa kwa triglycerides ndi cholesterol yokwanira kumatha kuwonetsa matenda akulu monga atherosulinosis.
Kuperewera kwa chithandizo kungayambitse mapangidwe a cholesterol plaque ndi chotengera chotchinga.
Kuchepetsa mulingo wa TAG, ma algorithm otsatirawa ayenera kutsatiridwa:
- Kusintha ndi chikhalidwe cha zakudya. Malangizowa akutanthauza kuchepa kwakanema kwa chakudya cha caloric, m'malo mwa kudya chakudya champhamvu chomanga thupi mwachangu ndi zakudya zomwe zimakhala ndi fiber komanso kugaya chakudya pang'onopang'ono. Kuyambitsa chakudya chamafuta a masamba. Kupereka mavitamini ndi michere mineral.
- Kukana kwathunthu zizolowezi zoipa. Zizoloŵezi zakupha zimaphatikizapo kumwa mowa kwambiri ndi kusuta. Zothandiza kwa thupi ndikumwa tsiku lonse la vinyo wofiira wofunda muyezo wosaposa 50 ml. Kusuta ndi vuto lalikulu kwambiri, lomwe limapangitsa kuti mitsempha ya magazi iwonjezeke komanso matenda osavomerezeka a bronchitis. Fodya amathandizanso kuyang'ana kwamwazi ndipo amalimbikitsa thrombosis.
- Matenda a zolimbitsa thupi. Kuchita masewera olimbitsa thupi pafupipafupi kumathandizira kuchepetsa kunenepa ndi mafuta m'thupi, omwe amachepetsa mwachangu kuchuluka kwa TAG ndikumasula magazi kuti asamachulukane kwambiri.
Panthawi yakusokonekera kwa mafuta, zimakhala zokwanira kusintha ntchito ya zakudya ndi zamagalimoto kuti zitheke kuthana ndi TAG.
Ngati njirazi sizothandiza, mankhwalawa ayenera kuyambiranso.
Zambiri za pharmacological mankhwala
Conservative therapy ikuchitika moyang'aniridwa ndi adokotala. Kutalika kwa mankhwalawa kumatengera kuchuluka kwa TAG, cholesterol ndi atherogenic lipoproteins.
Kukhazikitsidwa kwa Fenofibrit ndi Gemfibrozil kumatha. Malinga ndi gulu, ndalamazi zimaphatikizidwa m'gulu la michere. Tsoka ilo, gulu la mankhwalawa nthawi zambiri limabweretsa zovuta. Nthawi zambiri, akumatenga ma ulusi a wodwalayo, amadandaula za kudzimbidwa ndi kupweteka pakuwonekera kwa ndulu.
Kugwiritsa ntchito kwa ma fiber kuphatikiza ndi ma statins sikulimbikitsidwa, chifukwa angayambitse myolysis wamkulu.
Nicotinic Acid kapena kusinthidwa kwake, nicotinamide, ndiyenso mankhwala othandiza. Kutenga nicotinic acid kumathandiza kutsitsa triglycerides m'mwazi. Zowonjezera zake ndizokhoza kuwonjezera kuchuluka kwa anti-atherogenic lipoproteins. Zotsatira zoyipa zikuluzikulu ndizoyenda, kuyaka ndi redness pakhungu. Zotsatira zake zimaphatikizidwa ndi chizindikiro cha vasodilation.
Statin ndi mankhwala omwe ali ndi mphamvu yolimbana ndi antilipid, omwe amathandizira kuchepa kwa kuchuluka kwa zigawo zonse za lipid. Statin amagwiritsidwa ntchito nthawi zambiri kuthetsa hypercholesterolemia.
Njira yotetezedwa komanso yothandiza yochepetsera TAG ndi mafuta am'madzi kapena omega-3 ndi omega-6 acids. Zatsimikiziridwa kuti kudya pafupipafupi 1 gramu yamafuta am'madzi patsiku kumachepetsa chiopsezo cha matenda amtima ndi 40 peresenti.
Mafuta a Omega ali ndi vuto linalake loti azigwiritsa ntchito tizigawo ting'onoting'ono ta lipid. Ichi ndichifukwa chake ali ndi kutchulidwa kotereku pakuchepetsa triglycerides ndi cholesterol.
Popewa, mutha kuyamba kudya ma omega acid mukadali aang'ono.
Momwe mungasinthire kagayidwe ka lipid kumuuza katswiri muvidiyoyi.
