Mankhwala Augmentin: malangizo ntchito

Augmentin ndi mankhwala ophatikiza antibacterial omwe amagwiritsidwa ntchito pochiza ana ndi akulu. Ubwino wa mankhwalawa ndi kuthekera kugwiritsa ntchito muubwana.

Ath

Mankhwala olimbana ndi mankhwalawa amaphatikizidwa ndi gulu la mankhwala a anatomical-Therapeutic-kemikali. Zotsirizirazi ndizovomerezeka ndi WHO. Code J01CR02.

Ubwino wa mankhwalawa ndi kuthekera kugwiritsa ntchito muubwana.

Kutulutsa mafomu ndi kapangidwe ka Augmentin

Pali mitundu iwiri ya yotulutsira mankhwala: mapiritsi ndi ufa womwe kuyimitsako kumakonzedwa. Mankhwalawa sapezeka mu madzi. Mosiyana ndi Flemoxin Solutab, mitundu iwiri yogwira imakhalapo pakukonzekera nthawi yomweyo: clavulanic acid ndi amoxicillin.

Mapiritsi

Mapiritsi okhala ndi 125 mg ya clavulanic acid ali ndi mawonekedwe ozungulira (oval). Ndizoyera ndi dzina la Augmentin. Mapiritsi amayikidwa m'matumba a zidutswa 7 kapena 10, ma CD ndi ma CD ndi ma CD opangidwa ndi zojambulazo. Zosakaniza zina zimaphatikizira ndi magnesium stearate, silicon dioxide, cellulose, ndi wowonda wa carboxymethyl. Nembanemba wamafilimu amakhala ndi macrogol, hypromellose ndi zina zowonjezera.

Mapiritsi a Augmentin amayikidwa m'matumba a zidutswa 7 kapena 10.

Ufa

Nthawi zambiri, ufa amapatsidwa mankhwala. Imayera ndi fungo labwino. Akasakanizidwa ndimadzimadzi, maluwa oyera amawoneka. Zothandiza zothandizazo ndi ufa ndi succinic acid, aspartame, kununkhira, hypromellose, chingamu ndi silicon dioxide.

Njira Zothetsera

Amabayidwa (m'mitsempha kapena minofu ya gluteus) pamene wodwalayo ali ndi vuto lalikulu.

Njira yamachitidwe

Mankhwalawa amawononga mabakiteriya a gramu-gramu komanso gramu. Ili ndi beta-lactamase inhibitor, yomwe imapangitsa kuwonongeka kwa ma micros enzyme omwe amachita mankhwala osokoneza bongo okhala ndi mphete ya beta-lactam. Zonsezi zimawonjezera mphamvu ya mankhwalawa.

Mabakiteriya opanda gramu komanso gram alibe chiopsezo ku Augumentin.

Otsatirawa atengedwa ndi Augmentin:

• nocardia;
• mndandanda;
• causative wothandizila wa anthrax;
• streptococci;
• staphylococci;
• causative wothandizira wa pertussis;
• Helicobacter pylori;
• moraxella;
• zamatsenga;
• causative wothandizila wa borreliosis;
• treponema;
• leptospira;
• ndodo za hemophilic;
• cholera vibrio;
• gramu-alibe anaerobes (bacteriode, fusobacteria, clostridia).

Tizilombo ta intracellular (chlamydia, mycoplasmas), yersinia, enterobacter, acinetobacteria, cytrobacter, serrations, morganella ndi legionella zimagwirizana ndi mankhwalawa. Klebsiella, Proteus, Salmonella, Shigella, Escherichia coli, Enterococci, Corynebacteria ndi mitundu ina ya streptococci atha kukhala kuti adagwirizana ndi mankhwala.

Gawo lalikulu la antibayotiki (amoxicillin) ndi bactericidal, ndiye kuti, limapha mabakiteriya.

Pharmacokinetics

Mukamamwa, zigawo zikuluzikulu zimalowa mwachangu m'mimba. Kuyamwa kwambiri (kuyamwa) kumawonedwa mukamamwa mankhwalawa koyambirira kudya. Zigawozi zimaphatikizana m'mapuloteni ndipo zimagawidwa m'thupi lonse. Clavulanate ndi amoxiclav zimapezeka zochuluka kwambiri m'mafupa, minofu, minofu ndi ziwalo za parenchymal, komanso zovuta zam'mimba.

Zigawo za Augmentin zimatha kulowa mu placenta, popanda kuyambitsa kusokonezeka kwa fetal. Zinthu zomwe zimagwira zimadutsa m'matumbo a mabere ndi mkaka wa m'mawere. Mpaka 25% ya mankhwala omwe adalowetsedwa ndi impso. Clavulanic acid imapangidwa mofulumira ndikupukusira impso, ndowe ndi mpweya kudzera m'mapapu. Amoxicillin amapakidwa mu mkodzo wokha.

Zigawo za Augmentin zimatha kulowa mu placenta, popanda kuyambitsa kusokonezeka kwa fetal.

Zizindikiro zogwiritsidwa ntchito

Matenda omwe amathandizidwa ndi Augmentin:

1. Zofooka pakhungu ndi minofu yofewa. Izi zimaphatikizapo streptoderma ndi staphyloderma (folliculitis, ecthyma, impetigo, ostiofolliculitis, hydradenitis, zithupsa, carbuncle).
2. Zofooka zam'mapapo kupuma thirakiti ndi mapapo (tonsillitis, kuwonongeka kwa bronchi, sinus kutupa, matenda a tenillitis, kutupa kwa khutu, tracheitis, chibayo).
3. Pathology ya genitourinary system (pachimake ndi matenda a cystitis, urethritis, kutupa kwa impso, prostatitis, vulvovaginitis, endometritis, salpingoophoritis, prostatitis).
4. Gonorrhea (matenda opatsirana pogonana kuchokera ku gulu la matenda opatsirana pogonana).
5. Osteomyelitis (suppurative yotupa yotupa matenda).
6. Matenda a mano ndi nsagwada (zotupa, periodontitis, kutupa kwa maxillary sinuses).
7. Mikhalidwe ya Septic.
8. Matenda a postoperative.
9. Kutupa kwa peritoneum (peritonitis).

Augumentin amathandizira matenda a pakhungu ndi zofewa.

Mankhwalawa amagwiritsidwa ntchito kwambiri pochiza matenda apumidwe am'mimba.

Mankhwalawa amatha kuthana ndi kuwonongeka kwa bronchial ndi chibayo.

Mankhwalawa amagwiritsidwa ntchito pa pathologies a genitourinary system ndi gonorrhea.

Mankhwala amamulembera zotupa za peritoneum.

Augumentin amaperekedwa pambuyo pa opaleshoni kuti apewe matenda.

Kodi angagwiritsidwe ntchito pa matenda a shuga

Kukhalapo kwa matenda ashuga sikukulepheretsa kugwiritsa ntchito Augmentin, koma kuyenera kugwiritsidwa ntchito mosamala. Ndikofunikira kuwongolera kuchuluka kwa shuga m'magazi.

Odwala omwe ali ndi vuto lalikulu la matenda ashuga nephropathy (kuwonongeka kwa impso) sanapatsidwe mankhwala.

Contraindication

Zotsutsana ndi:

• mankhwala tsankho (hypersensitivity);
• ziwengo kwa beta-lactam antimicrobials;
• zaka odwala mpaka zaka 12 ndi kulemera kochepa kwa thupi (pansipa 40 makilogalamu a mapiritsi a 875, 250 ndi 500 mg);
• odwala zaka zosakwana miyezi 3 (ufa wa 200 ndi 400 mg);
• kukanika kwa impso;
• phenylketonuria (wa ufa).

Mankhwala opha tizilombo amathandizidwa mosamala kwa anthu omwe ali ndi vuto la chiwindi.

Ngati wodwala wawonongeka chiwindi, mankhwalawa amatchulidwa mosamala.

Momwe angatenge

Mankhwalawa ndi oyenera kugwiritsa ntchito kumayambiriro kwa chakudya, chifukwa izi zimachepetsa chiopsezo cha zotsatira zosafunikira. Augmentin angathe kumwedwa musanadye. Kuchulukitsa kwa kumwa mankhwalawa ndi katatu patsiku. Popereka mankhwala kwa ana, kuwerengera kwa mlingo kumafunidwa ndi adokotala. Mlingo umasinthidwanso pochiza anthu okalamba omwe ali ndi vuto laimpso. Pankhaniyi, chilolezo chimatengedwa.

Mukamagwiritsa ntchito ufa, kuyimitsidwa kwa 5 ml kukonzekera. Izi zimachitika musanadye. Madzi owiritsa firiji ya pachipinda amawonjezeramo vial, kenako imagwedezeka. Kuyimitsidwa kuyenera kuloledwa kupatsa pafupifupi mphindi 5, ndiye kuwonjezera madzi pamphingo yomwe mukufuna. Pambuyo pakugwedezeka, yankho limatha kumwa. Pambuyo pa dilution, mankhwalawa amasungidwa osaposa sabata mufiriji. Sayenera kuzizira.

Pangatenge masiku angati

Kutalika kwa matendawa kumatengera matenda oyambira ndipo kuyambira masiku 5 mpaka 14.

Pambuyo pa kuchepetsedwa, kuyimitsidwa koyimitsidwa kumasungidwa mufiriji osapitilira sabata.

Zotsatira zoyipa

Kumwa mankhwala nthawi zambiri kumayendera limodzi ndi zovuta (zoyipa). Kusintha kumeneku ndikosakhazikika ndipo kumatha atasiya kulandira chithandizo.

CNS

Kuchokera pakati mantha dongosolo n`zotheka:

• mutu
• Chizungulire
• kuchuluka kwa zochitika (sizimawonedwa kawirikawiri);
• wodwala matenda;
• chisokonezo cha kugona;
• wokongola
• Kusintha kwa machitidwe.

Zotsatira zoyipa za Augmentin kuchokera ku dongosolo lamanjenje lam'mutu ndizopweteka mutu, chizungulire komanso kusowa tulo.

Izi zimatha kusintha ndipo ndizotheka panthawi iliyonse ya mankhwala othandizira.

Kuchokera m'mimba thirakiti

Kuchokera kumbali yamakina am'mimba, zotsatirazi zosavomerezeka zimawonedwa:

• kuphwanya chopondapo ngati m'mimba;
• nseru (amapezeka ndi mlingo waukulu wa mankhwalawa);
• kusanza
• Kusintha kwa dzino enamel.

Nthawi zina colitis (kutupa kwamatumbo akulu), gastritis (kutupa m'mimba) ndi stomatitis (kutupa kwa mucosa wamlomo) kumayamba.

Zotsatira zoyipa izi zitha kupewedwa ngati mumwa maantibayotiki malinga ndi malangizo.

Njira yamikodzo

Izi ziwalo ndizosowa kwambiri. Nthawi zina pamakhala ma nephritis apakati, hematuria (kaphatikizidwe wamagazi mumkodzo) ndi crystalluria (mawonekedwe amchere mumkodzo).

Dongosolo lachitetezo

Sivutika pakumwa maantibayotiki. Mwina kukula kwa angioedema (chifukwa cha ziwengo zamankhwala), anaphylaxis, serum syndrome ndi vasculitis (kutupa kwa mtima).

Khungu komanso mucous nembanemba

Nthawi zina candidiasis a pakhungu ndi mucous nembanemba.

Chimodzi mwazotsatira zoyipa za mankhwalawa ndikupanga ma candidiasis a mucous membrane.

Kuchokera ku magazi ndi dongosolo la zamankhwala

Pogwiritsa ntchito mankhwalawa, nthawi zina amadziwika:

• kutsika kwa kuchuluka kwamaselo oyera m'magazi (leukopenia);
• kuchepetsa kupatsidwa zinthu za m'magazi;
• hemolytic anemia;
• agraulocytosis obweza;
• kuchuluka kwa nthawi ya magazi;
• magazi
• eosinophilia (kuchuluka kwa chizolowezi cha eosinophils m'magazi).

Chiwindi ndi matenda a biliary

Nthawi zina, kuchuluka kwa michere ya chiwindi m'magazi a odwala imachulukanso. Zosiyanasiyana zomwe zimachitika ndi jaundice, hepatitis (kutupa kwa chiwindi), kuchuluka kwa bilirubin ndi phosphatase yamchere. Izi zosafunikira zimapezeka makamaka mwa anthu okalamba.

Malangizo apadera

Mukasankha Augmentin, adokotala aziganizira osati zokhazo komanso zotsutsana, komanso malangizo apadera. Mukamachita zochizira, simungamamwe mowa wotsika mtengo komanso wokwera mtengo.

Mukamamwa Augumentin, simungamwe zakumwa zoledzeretsa.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Ndikwabwino kusagwiritsa ntchito mankhwala mukanyamula mwana. Maphunziro ambiri pazokhudza kukula kwa fetal sanachitike. Mukamayesa mankhwalawa mu nyama, kunalibe mphamvu ya teratogenic ya mankhwalawa. Maantibayotiki amatha kupatsidwa nthawi yoyamwitsa. Ngati zosafunikira zikuchitika, siyani chithandizo.

Mlingo wa ana

Mphamvu ya kuyimitsidwa imawonetsedwa kwa mwana mpaka zaka 12. Ndi kulemera kwa makilogalamu 40 kapena kupitirira apo, mankhwalawa samasiyana ndi akulu. Kuthandiza ana kuyambira miyezi itatu mpaka 12 ingachitike ndi kuyimitsidwa kwa 4: 1 (katatu patsiku) ndi kuyimitsidwa kwa chiwerengero cha 7: 1 (2 kawiri pa tsiku). Mukakhala pa hemodialysis zida, mankhwalawa amatha kumwa 1 nthawi patsiku.

Gwiritsani ntchito mu ukalamba

Kusintha kwa Mlingo kumachitika kokha ndi matenda a impso.

Odwala omwe ali ndi vuto la chiwindi

Pa mankhwala, chiwindi chimayang'aniridwa (kuyesa kwamwazi wamagazi).

Pochiza ndi Augumentin, mawonekedwe a chiwindi cha wodwalayo amayang'aniridwa.

Odwala ndi mkhutu aimpso ntchito

Mapiritsi a 1000 mg (pazinthu zomwe zimagwiritsidwa ntchito) amagwiritsidwa ntchito pokhapokha mkodzo wa creatinine chilolezo choposa 30 ml / min. Kubayidwa kumakomera.

Zokhudza mphamvu pakuwongolera njira

Maantibayotiki atha kuyambitsa chizungulire, chifukwa nthawi yayitali ya chithandizo muyenera kukana kugwira ntchito ndi zida komanso magalimoto oyendetsa.

Bongo

Zizindikiro za Augmentin zosokoneza bongo ndi:

• vuto la dyspeptic (kupweteka kwam'mimba, kutulutsa, kutsegula m'mimba, kusanza, kusanza);
• Zizindikiro za kuchepa thupi (kuthamanga kwa khungu, kuthamanga kwa mtima, kufooka);
• kukokana
• Zizindikiro za kuwonongeka kwa impso.

Pa mlingo wa 1000 mg, jakisoni wa mankhwala amakonda.

Thandizo limakhala pakuletsa mankhwalawa, kugwiritsa ntchito mankhwala opatsirana, kulowetsedwa, kutenga ufiti, kutsuka m'mimba ndi kuyeretsa magazi ndi hemodialysis.

Kuchita ndi mankhwala ena

Sitikulimbikitsidwa kugwiritsa ntchito kuphatikiza kwa amoxicillin ndi clavulanic acid ndi probenecid nthawi imodzi. Akaphatikizidwa ndi allopurinol, ziwengo nthawi zambiri zimachitika. Ndi munthawi yomweyo kugwiritsa ntchito mankhwala a penicillin omwe ali ndi methotrexate, kawopsedwe kameneka kamawonjezeka.

Analogi

Zofanana ndi Augmentin ndi mankhwala Amoxiclav. Mwa makina ochitira, Suprax ali pafupi ndi antibayotiki. Ichi ndikuyimira gulu la cephalosporins. Zomwe zimagwiritsidwa ntchito ndi cefixime. Mankhwalawa amapezeka mu mawonekedwe a makapisozi ndi granules.

Zosungidwa Augmentin

Kutentha kosungira - mochepera + 25ºC. Sungani mankhwalawo pamalo owuma osawonekera kwa ana. Kuyimitsidwa kumasungidwa mufiriji pamtunda wa +2 mpaka + 8ºC.

Mankhwala othandizira amaperekedwa pokhapokha ngati mwalandira mankhwala.

Tsiku lotha ntchito

Ufa wosasulidwa umasungidwa kwa zaka zitatu. Moyo wa alumali wa mapiritsi ndi zaka ziwiri ndi zitatu, kutengera zomwe zili ndi zinthu zomwe zikugwira ntchito.

Kupita kwina mankhwala

Mankhwala othandizira amaperekedwa pokhapokha ngati mwalandira mankhwala.

Mtengo wa Augmentin

Mtengo wamba wa mankhwalawa m'masitolo ndi ma 250 ruble ruble.

Ndemanga za Augmentin

Cyril, wazaka 35, Perm: "Posachedwa, pakufufuza kachilomboka kuchokera mu urethra, kachilombo ka chinzonono kamapezeka. Mapiritsi a Augmentin adalembedwa.

Elena, wazaka 22, ku Moscow: "Pambuyo pobadwa movuta, sepsis idayamba. Madokotala adabayira jakisoni yochokera ku amoxicillin ndi clavulanic acid. Tsopano ndikumva bwino."

Alexander, wazaka 43, Nizhny Novgorod: "Masabata angapo apitawa ndidadwala matenda a pyelonephritis. Ndinadandaula za ululu wammbuyo komanso kutentha thupi. Dotolo adandiuza kuti ndithandizidwe ndi Augmentin. Patatha masiku ochepa, ndidasintha."