Zochizira matenda angapo a impso ndi minofu ya mtima, matenda oopsa ndi zina, ndimagwiritsa ntchito mankhwala apadera, omwe amakhala ndi zilembo za angiotensin zotembenuza. Mankhwalawa ndi amodzi othandiza kwambiri. Amagwiritsidwa ntchito osati kungochiritsa, komanso kupewa mitundu yambiri yamavuto (mwachitsanzo, stroko ndi myocardial infarction).
Dzinalo
Dzina la malonda - Hartil Am. Dzinali m'Chilatini ndi Hartil. INN - Ramipril.
Hartil ndi njira imodzi yochizira matenda angapo a impso ndi minofu ya mtima, matenda oopsa ndi zina.
ATX
Gulu la ATX: Ramipril - C09AA05.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwalawa amapangidwa mwa mawonekedwe a mapiritsi ozungulira a lalanje-pinki ndi pinki (5 mg) kapena oyera (10 mg). Chithandizo chogwira mankhwalawa ndi ramipril. Zothandiza:
- iron oxide;
- lactose monohydrate;
- wowuma;
- sodium bicarbonate.
Mankhwalawa amapangidwa mwa mawonekedwe a mapiritsi ozungulira a lalanje-pinki ndi pinki (5 mg) kapena oyera (10 mg).
- Zotsatira za pharmacological
Mankhwala ali ndi hypotensive. Zimakhudza osati magazi okha, komanso minofu ngakhale makoma amitsempha yamagazi.
Mankhwalawa amateteza kutulutsa kwamtima, kumachepetsa kuthamanga kwa m'mapapo m'mitsempha, kumachepetsa kuthamanga kwa magazi ndikupanga mitsempha yamagazi.
Mphamvu ya antihypertensive imawonedwa patatha maola 1-2 mutatha kumwa mankhwalawa, koma imafika pang'onopang'ono patatha maola 3-6 ndipo imatha tsiku limodzi.
Njira ya mankhwala ndi mankhwalawa imathandizira kukhazikika kwa magazi mu masabata 3-4 ogwiritsira ntchito.
Pharmacokinetics
Pambuyo pakumwa pakamwa mankhwala, ake okangalika ndi othandizira amathandizidwa kuchokera m'mimba. Kuzindikira kwakukulu mu plasma ya magazi kumafikiridwa pakatha mphindi 60-70 pambuyo pa kuperekedwa.
Mankhwala amakonzedwa makamaka mu chiwindi ndi kumasulidwa kwa metabolites (osagwira ntchito). Mankhwalawa amachotseredwa ndowe (40%) ndi mkodzo (60%).
Zizindikiro zogwiritsidwa ntchito
Malangizo a mankhwalawa akuwonetsa:
- aakulu mawonekedwe a mtima kulephera kwa mtima (makamaka pambuyo myocardial infarction);
- matenda oopsa;
- matenda ashuga nephropathy;
- aakulu a matenda aimpso.
Mankhwala amachepetsa mwayi wokhala ndi matenda opha ziwalo, myocardial infarction ndi "kufa kwa coronary."
Contraindication
Zoletsa kugwiritsa ntchito mankhwalawa:
- tsankho;
- mkaka wa m`mawere ndi pakati;
- zaka zosakwana 18;
- magazi matenda;
- kuthamanga kwa magazi;
- anasamutsa angioedema;
- aimpso mtsempha wamagazi stenosis;
- kuchuluka kwa aldosterone (hyperaldosteronism).
Mimba ndi imodzi mwazomwe zimakhudzana ndi kugwiritsa ntchito mankhwalawa.
Ndi chisamaliro
Poyang'aniridwa mosamala ndi madokotala, mankhwalawa akhoza kutengedwa motere:
- mitral kapena aortic stenosis;
- mitundu yoyipa ya ochepa matenda oopsa;
- angina pectoris wosakhazikika;
- chiwindi / kulephera kwa impso;
- matenda a shuga;
- pambuyo kupatsirana kwa impso;
- odwala okalamba, etc.
Odwala okalamba ayenera kumwa mankhwalawa mosamala.
Momwe mungatenge Hartil
Kutsimikizira kwa mankhwalawa kumati kuyenera kumamwa mkati, i.e. pakamwa, ngakhale chakudyacho. Sikoyenera kutafuna mapiritsi. Mlingo amasankhidwa ndi dokotala payekhapayekha pa vuto lililonse. Komabe, pali mitundu ya mankhwala:
- ochepa matenda oopsa: poyamba 2.5 mg ya mankhwala zotchulidwa patsiku, ndiye kuchuluka kwake;
- Kulephera kwa mtima kosatha: 1.25 mg patsiku;
- kuchira pambuyo infarction wa myocardial: koyamba mlingo - mapiritsi 2 a 2 mg 2 kawiri pa tsiku (ndikofunikira kuyamba kumwa mankhwala 2-9 patatha masiku a kuukira);
- nephropathy: 1.25 mg / tsiku;
- kupewa myocardial infarction, sitiroko ndi mavuto ena a mtima dongosolo: 2,5 mg / tsiku.
Mulingo waukulu wa mankhwalawa ndi 10 mg patsiku.
Kutsimikizira kwa mankhwalawa kumati kuyenera kumamwa mkati, i.e. pakamwa, ngakhale chakudyacho.
Ndi matenda ashuga
Odwala omwe ali ndi matenda ashuga omwe amamwa mankhwala ayenera kuwongolera shuga lawo lamwazi. Ngati ndi kotheka, dokotala amatha kusintha kuchuluka kwa insulin.
Zotsatira zoyipa
Mukamagwiritsa ntchito mankhwala pamakhala chiwopsezo cha mawonekedwe owonetsa. Alipo ambiri a iwo, motero nkhaniyi iyenera kuphunzira pasadakhale.
Matumbo
Zotsatira zoyipa zalembedwa:
- kutsegula m'mimba
- kusanza
- nseru
- cholestatic jaundice;
- kapamba
- kupweteka kwam'mimba, etc.
Kuchokera m'matumbo, zovuta zoyambitsa mseru komanso kusanza zimatha kuchitika.
Hematopoietic ziwalo
Zowonekera:
- leukocytopenia;
- kuchepa magazi
- thrombocytopenia;
- hemolytic mawonekedwe a kuchepa magazi;
- agranulocytosis;
- kuchepa kwa chiwerengero cha maselo ofiira a m'magazi;
- kuponderezana kwa mafupa a hematopoiesis.
Pakati mantha dongosolo
Zotsatira zoyipa ndi izi:
- mutu
- Chizungulire
- minofu kukokana;
- kukokana
- mavuto okhumudwitsa;
- kuda nkhawa;
- kuchuluka kukwiya;
- kusintha kwakuthwa;
- kukomoka.
Mutu ndi chimodzi mwazotsatira zoyipa.
Kuchokera ku genitourinary system
Otsatirawa akuti:
- kusabala
- utachepa libido;
- kuchuluka kwa kulephera kwa impso;
- kutupa kwa nkhope, miyendo ndi mikono;
- oliguria.
Kuchokera ku kupuma
Wodwalayo amatha kusokonezedwa ndi:
- kutsokomola ndi zilonda zapakhosi;
- bronchial kukokana;
- bronchitis, laryngitis, sinusitis, rhinitis;
- kupuma movutikira.
Zotsatira zoyipa za kupumira thirakiti, kutsokomola kumatha kuchitika.
Matupi omaliza
Zotsatira zoyipa zimakhala ndi mawonekedwe awa:
- zotupa pakhungu ndi kuyabwa;
- conjunctivitis;
- zithunzi;
- matupi awo sagwirizana ndi dermatitis ;;
- Edema wa Quincke.
Malangizo apadera
Mukamagwiritsa ntchito mapiritsi, odwala amafunikira kuwunika mosamala madokotala. Izi zili choncho makamaka masiku oyamba kudya. Pakupita maola 8 mutatha kugwiritsa ntchito, ndikofunikira kuyeza kuthamanga kwa magazi.
Musanagwiritse ntchito mankhwalawa, muyenera kusintha kuchepa kwa thupi ndi Hypovolemia.
Odwala ndi mtima pathologies mu impso, ndi mkhutu aimpso ntchito ndipo pambuyo kupatsidwa chiwalo amafunikira kuyang'anira mosamala kwambiri zamankhwala.
Odwala ndi mtima pathologies mu impso, ndi mkhutu aimpso ntchito ndipo pambuyo kupatsidwa chiwalo amafunikira kuyang'anira mosamala kwambiri zamankhwala.
Zokhudza mphamvu pakuwongolera njira
Ndi kuchepa kwa kuthamanga kwa magazi kwa odwala omwe amagwiritsa ntchito mankhwalawa, ndikofunikira kuti asiye kusiya kasamalidwe ka mayendedwe ammisewu ndi zida zina zovuta kupanga.
Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere
Ndi zoletsedwa kugwiritsa ntchito mankhwalawa panthawi yomwe muli ndi pakati, chifukwa zinthu zake zomwe zimagwira zimatha kusokoneza kukula kwa fetal. Ndi mkaka wa m`mawere ndi kupezeka kwa mankhwala, kuyamwitsa kuyenera kuyimitsidwa.
Kukhazikitsidwa kwa Hartil kwa ana
Ndi zoletsedwa kugwiritsa ntchito mankhwalawa kwa odwala osakwana zaka 15. Mpaka azaka 18, mankhwalawa amamwa mankhwala ocheperako ndipo amayang'aniridwa ndi achipatala.
Ndi zoletsedwa kugwiritsa ntchito mankhwalawa kwa odwala osakwana zaka 15.
Gwiritsani ntchito mu ukalamba
Kwa odwala okalamba, mankhwalawa amadziwitsidwa ngati palibe contraindication komanso mankhwala ochepa. Ngati pali diuretic iliyonse yogwiritsidwa ntchito, mlingo uyenera kusankhidwa mosamala.
Bongo
Ngati muyeso wa mankhwalawo udakwaniritsidwa, mawonedwe osayenera awa akhoza kuchitika:
- zolephera pamiyeso yama electrolyte;
- kutsika kwa kuthamanga kwa magazi;
- kukula kwa aimpso kulephera.
Ndi mankhwala osokoneza bongo pang'ono, wodwalayo ayenera kutsuka m'mimba, komanso kumwa sodium sulfate ndi enterosorbents.
Zizindikiro zopweteka komanso kuchepa kwakukulu kwa kuthamanga kwa magazi, kugwiritsa ntchito angiotensin ndi catecholamines kukuwonetsedwa. Hemodialysis ndi mankhwala osokoneza bongo sikugwira ntchito.
Kuchita ndi mankhwala ena
Mukaphatikiza mankhwalawa ndi procainamide, corticosteroids, allopurinol, hydrochlorothiazide zotumphukira ndi zinthu zina zomwe zimapangitsa kusintha kwa kapangidwe ka magazi, mwayi wokhala ndi zovuta m'magazi a hematopoietic ukuwonjezeka.
Mukaphatikiza mankhwalawa ndi othandizira a hypoglycemic, pamakhala chiopsezo chochepetsa shuga wamagazi ndi chiwindi chodwala.
Ndiosafunika kugwiritsa ntchito diuretics ndi potaziyamu m'malo mwake ndi mankhwalawa chifukwa chitha kukhala ndi hyperkalemia. Kuchiza ndi ACE inhibitor kuyenera kuchitika moyang'aniridwa ndi achipatala.
Kuyenderana ndi mowa
Chifukwa chakuti mankhwalawa amagwira ntchito popanga mankhwala, amaletsa kumwa mowa komanso mankhwala omwe amakhala ndi mowa mukamamwa mankhwalawo. Zomwezi zimanenedwanso mu malangizo ogwiritsira ntchito mankhwalawa.
Chithandizo chogwira mankhwalawa chimatha kupititsa patsogolo zotsatira za Mowa, ndizoletsedwa kumwa mowa mukamamwa mankhwalawo.
Wopanga
Kampani ya Malta ACTAVIS kapena kampani yopanga mankhwala aku Icelandic ACTAVIS hf. Choyimira - EGIS CJSC "Bizinesi ya Mankhwala".
Analogi
Mawu ofanana kwambiri ndi a ku Russia:
- Mapiramidi;
- Amprilan;
- Wazolong;
- Amlo;
- Ramipril;
- Tsata;
- Ramicardia;
- Dilaprel, etc.
Kupita kwina mankhwala
Mutha kugula mankhwala pafupi ndi mankhwala aliwonse.
Mutha kugula mankhwala pafupi ndi mankhwala aliwonse.
Kodi ndingagule popanda kulandira mankhwala?
Mutha kugula kokha mapiritsi ndi mankhwala.
Mtengo wa Hartil
Mtengo wa 1 paketi la mankhwalawa kuchokera pamapiritsi 28 umayambira ku ruble 460.
Zosungidwa zamankhwala
Mankhwalawa amasungidwa m'malo owuma komanso amdima. Ulamuliro wabwino kwambiri wotentha + ndi 15 ... + 25 ° C.
Tsiku lotha ntchito
Mpaka zaka ziwiri mutapanga.
Ndemanga za Hartil
Mankhwala ambiri amayankhidwa mbali yabwino. Izi zimachitika chifukwa cha mtengo wotsika mtengo komanso kuchuluka kwa ntchito yake.
Omvera zamtima
Ivan Korkin (wamtima), wazaka 40, Voronezh
Ndikupangira mankhwala othandizira matenda oopsa, kulephera kwa mtima, ndi zina zambiri zamatenda. Pofuna kupewa zovuta, muyenera kusankha mulingo woyenera.
Inga Klemina (wamtima wazaka), wazaka 42, ku Moscow
Mankhwalawa akhala akufunika pakati pa odwala anga. Mwiniwake adagwiritsa ntchito popewa kukula kwa kulowerera kwa mtima. Popeza ntchito yogwira pophika mankhwala, kuti akwaniritse zochizira, Mlingo uyenera kusankhidwa pokhapokha mutafufuza bwino za matenda azachipatala a odwala.
Odwala
Vladislav Pankratov, wazaka 36, Lipetsk
Ndimadwala matenda a shuga omwe amadalira insulin, imodzi mwazovuta zake ndi matenda oopsa. Adotolo apereka mapiritsi awa. Ndakhala ndikumwa iwo kwa miyezi pafupifupi 2,5. Zowongolera zikuwoneka, koma posachedwapa anayamba kumva chizungulire poyenda nthawi yayitali. Ndipita kuchipatala kuti ndikaonane.
Elvina Ivanova, wazaka 45, Vladivostok
Momwe magazi anga atayamba "kulumpha", adotolo adandipatsa mankhwala. Amva bwino patatha milungu iwiri atayamba kulandira chithandizo. Tsopano ndimawalandira kuti ateteze zina.
