Glucofage 750 - njira yolimbana ndi matenda ashuga

Glucofage 750 - mankhwala omwe amagwiritsidwa ntchito pochiza matenda amtundu wa 2 shuga.

ATX

Khodi ya ATX ndi A10BA02.

Kutulutsa mafomu ndi kapangidwe kake

Mankhwalawa amapezeka mwa mapiritsi a biconvex okhala ndi mtundu woyera. Piritsi 1 ili ndi 750 mg yogwira ntchito - metformin hydrochloride.

Kuphatikiza apo, caramellose, hypromellose, magnesium stearate imaphatikizidwanso.

Glucofage 750 - mankhwala omwe amagwiritsidwa ntchito pochiza matenda amtundu wa 2 shuga.

Zotsatira za pharmacological

Chombocho ndi cha gulu la mankhwala a hypoglycemic. Zinthu zomwe zimagwira ndi zotumphukira za Biguanides.

Metformin imayang'anira magulu onse a shuga ndi a postprandial. Thupi silikhudzika ndi katulutsidwe ka insulin chifukwa cha maselo a kapamba, chifukwa chake, silingayambitse kuchepa kwamphamvu kwa glucose.

Mankhwalawa amagwira pama insulin receptors omwe ali mu ziwalo ndi minofu. Kuthamanga kwa glucose processing ndi maselo otumphukira kumakulanso. Mothandizidwa ndi mankhwalawa, gluconeogenesis mu hepatocytes amaletsa.

Chithandizo chogwira ntchito chimachepetsa kuyamwa kwa glucose ndi matumbo a matumbo. Pansi pa kuchitapo kwake, kupanga glycogen kumathandizira, ntchito yotengera zamagulu omwe imayendetsa transmembrane kuonjezera shuga.

Pharmacokinetics

Mulingo woyenera kwambiri wa yogwira magazi m'madzi am'magazi umawonedwa pafupifupi mphindi 150 pambuyo pakumwa piritsi la Glucofage. Kutenga mankhwalawa pamimba yopanda kanthu sikukhudza mayamwidwe a mankhwalawa, omwe amakulolani kumwa ngakhale osadya.

Kugwiritsa ntchito nthawi yayitali mankhwala a metformin sikupangitsa kuti thupi lipangidwe. Ikalowa m'magazi, chinthucho sichimangofunika kunyamula ma peptides. Metformin metabolism imachitika mu mawonekedwe osagwirizana. Palibe metabolites yogwira yomwe yapezeka m'thupi la munthu. Kuchotsa kumachitika osasinthika.

Mankhwala amachotsedwa mothandizidwa ndi impso. Njira ya chimbudzi ndi kusefera kwake ndi kutulutsirana kwa tubular. Kutha kwa theka la moyo kumachokera ku maola 5 mpaka 7. Ngati aimpso ntchito, kuwonongeka kwa yogwira amayamba, ndipo theka moyo wawo ukuwonjezeka. Zotsatira zake, kuwonjezeka kwa plasma metformin pazotheka.

Mankhwala amachotsedwa mothandizidwa ndi impso.

Zizindikiro zogwiritsidwa ntchito

Glucophage amalembedwa mtundu wa matenda ashuga 2. Amagwiritsidwa ntchito ngati vuto lakudya latha. Itha kuthandizidwa onse ngati monotherapy, komanso ngati gawo la zovuta la mankhwala ndi ma hypoclycemic wothandizira kapena Insulin.

Contraindication

Chipangizocho chimaphatikizidwa mu milandu yotsatirayi:

• tsankho lililonse pazinthu zomwe zimapanga;
• kuwabwezera kwa matenda a shuga (ketoacidosis, precoma kapena chikomokere);
• kukanika kwa aimpso;
• kusakwanira kwa ntchito ya hepatobiliary system;
• uchidakwa wambiri kapena chakumwa chaukali;
• pachimake zinthu zoopseza impso;
• kulephera kwa mtima;
• kulephera kupuma;
• minofu hypoxia yolimbitsa kwambiri;
• lactic acidosis;
• Zakudya zochepa zopatsa mphamvu;
• kuchitapo kanthu kwa opaleshoni ndi kuvulala, komwe kumafuna kukhazikitsidwa kwa Mlingo waukulu wa insulin;
• kusowa kwamadzi;
• kugwedeza
• zochitika zakumwa kwambiri.

Ndi chisamaliro

Muyenera kusamala mukamapereka mankhwala kwa anthu opitilira zaka 60, omwe nthawi zambiri amakumana ndi zovuta zowonjezereka, ndikuchulukitsa chiopsezo cha lactic acidosis.

Kulephera kwa mtima ndikutsutsana ndi kugwiritsa ntchito glucophage.

Mankhwalawa sanapatsidwe mankhwala osokoneza bongo osatha.

Glucophage imaphatikizika mu chidakwa cha thupi.

Momwe mungatenge Glucofage 750?

Mapiritsi amatengedwa pakamwa. Gwiritsani ntchito nthawi yomaliza chakudya.

Akuluakulu

Akuluakulu omwe ali ndi matenda a shuga a mtundu wa 2 amatenga 750 mpaka 2000 mg wa metformin patsiku.

Kwa ana

Ana ochepera zaka 18 zakubadwa amalephera kugwiritsa ntchito mankhwalawa.

Chithandizo cha matenda a shuga Glucofage 750

Metformin imagwiritsidwa ntchito pochiza matenda amtundu wa 2 shuga. Amawerengera odwala omwe vuto lawo silingalipidwe ndi chakudya kapena zochita zolimbitsa thupi. Mankhwala amatchulidwa onse ngati monotherapy, komanso limodzi ndi Insulin ndi othandizira ena omwe ali ndi vuto la hypoglycemic. Sikulimbikitsidwa kuphatikiza mankhwala nokha. Kusankhidwa kwa mankhwala kuyenera kuperekedwa kwa adokotala.

Mankhwalawa matenda amtundu wa 2 shuga, mlingo wa metformin tsiku lililonse umatha kuchoka pa 750 mpaka 2000 mg. Mlingo woyenera udzasankhidwa ndi adokotala.

Metformin imagwiritsidwa ntchito pochiza matenda amtundu wa 2 shuga.

Kuchepetsa thupi

Kugwiritsa ntchito mankhwalawa pofuna kuchepetsa thupi popanda upangiri wa akatswiri sikulimbikitsidwa. Mlingo wa tsiku ndi tsiku wa kuchepa thupi ndi 100 mg, wogawidwa pawiri. Mulingo woyenera wamankhwala umatha masiku 20. Pambuyo pa izi, kupumula kwa mwezi umodzi kumachitika. Ndikotheka kubwereza maphunzirowa ngati kuli koyenera kuphatikiza zotsatira.

Mukamamwa metformin, simuyenera kumangodya zakudya zopatsa mphamvu pang'ono. Zakudya zosakwanira zimabweretsa chiwopsezo chowonjezereka cha zotsatira zoyipa. Kuphatikiza kwa mankhwalawa ndi Reduxin ndikotheka.

Zotsatira zoyipa

Matumbo

Kusanza ndi kusanza, masinthidwe amtulo, amachepetsa chilako, kupweteka m'dera la epigastric. Izi zosafunikira zimawonedwa kwambiri kumayambiriro kwa maphunziro, pambuyo pake zimadutsa pazokha. Kuti muchepetse chiopsezo chotsatira, sibwino kugwiritsa ntchito metformin pamimba yopanda kanthu. Kuwonjezeka kwapang'onopang'ono kwa mlingo kumakhalanso kotheka, komwe kumalola thupi kuti lizolowere zochitika za mankhwalawa.

Pakati mantha dongosolo

Kuphwanya kukoma. Mwina kuwoneka kwachitsulo kukamwa.

Kuchokera kwamikodzo

Metformin siyimabweretsa zotsatira zoyipa kuchokera kwamkodzo dongosolo.

Pa mbali ya chiwindi ndi biliary thirakiti

Nthawi zambiri, kuwonjezeka kwa milingo ya chiwindi michere ndi kuwonongeka kwa aimpso kungawonedwe. Zotsatira zosafunikira zimazimiririka atasiya ntchito.

Zotsatira zoyipa, kuphwanya kwamvekedwe wa kukoma kumatha kuchitika.

Kumayambiriro kwa maphunzirowa, mseru ndi kusanza zitha kuchitika.

Kuti muchepetse chiopsezo chotsatira, sibwino kugwiritsa ntchito metformin pamimba yopanda kanthu.

Malangizo apadera

Anthu omwe ali ndi vuto lalikulu la impso amakhala pachiwopsezo cha metamorphine cumulation. Zotsatira zake, lactic acidosis imatha kuchitika, yomwe ndiyosowa, koma yowopsa thanzi la munthu ndi moyo. Kuopsa kwa vutoli kumapezekanso mwa anthu omwe ali ndi vuto la kusokonezeka kwa magazi, kudalira mowa, ketosis, komanso matenda osokoneza bongo panthawi yovunda.

Lactic acidosis imatha kukayikiridwa ngati wodwala atayamba kupweteka minofu, kukokana, komanso kusokonezeka kwa m'mimba thirakiti yoyambira maziko a Metformin. Laboratory complication imawonetsedwa ndi kuchepa kwa asidi m'magazi omwe ali pansi pa 7.25, mulingo wa lactate ukuwonjezeka mpaka 5 mmol / l ndikukwera. Ngati mukukayikira kuti lactic acidosis yakula, funsani dokotala nthawi yomweyo. Chifukwa chodzikundikira lactate yambiri, chikomokere chimatha kuchitika.

Glucophage siyikulimbikitsidwa kuti izitengedwa masiku awiri asanafike komanso atatha kuchitira opaleshoni kapena njira zama radiology.

Musanayambe maphunziro, ndikofunikira kudziwa ntchito ya aimpso. Pachifukwa ichi, chilolezo cha creatinine chimawunikidwa. Pogwiritsa ntchito metformin mosalekeza, kuwunika mobwerezabwereza kuyenera kuchitika osachepera 1 pachaka.

Anthu omwe ali ndi vuto la chiwindi ayenera kumwa mankhwala mosamala.

Kuyenderana ndi mowa

Kumwa mowa panthawi ya mankhwala ndi metformin sikulimbikitsidwa.

Zokhudza mphamvu pakuwongolera njira

Ndi zovuta zovuta za matenda ashuga pogwiritsa ntchito ma hypoglycemic wothandizira, hypoglycemia imatha kuchitika, pomwe kuyendetsa kapena njira zovuta kumatsutsana.

Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere

Pa nthawi yoyembekezera, wodwala amene akutenga Glucofage ayenera kusamutsidwa kupita ku insulin. Ngati ndi kotheka, chithandizo cha mayi woyamwitsa, mwanayo amasinthidwa kuti adyetse maupa.

Pa nthawi yoyembekezera, wodwala amene akutenga Glucofage ayenera kusamutsidwa kupita ku insulin.

Kugwiritsa ntchito mankhwalawa kumatheka mwa okalamba.

Pa mankhwala ndi glucophage, osavomerezeka kuwongolera galimoto.

Gwiritsani ntchito mu ukalamba

Kugwiritsa ntchito mankhwalawa ndikotheka kwa anthu okalamba pakakhala zosagwirizana ndi malangizo omwe angagwiritsidwe ntchito.

Bongo

Mankhwala osokoneza bongo a metformin ndi osowa. Mukamagwiritsa ntchito mlingo kakhumi poyerekeza ndi achire, lactic acidosis imayamba. Pankhaniyi, muyenera kusiya kugwiritsa ntchito malonda. Wodwalayo amagonekedwa kuchipatala komwe ma lactate amayang'aniridwa. Ngati ndi kotheka, hemodialysis ndi symptomatic mankhwala.

Kuchita ndi mankhwala ena

Kuphatikiza kophatikizidwa

Glucophage sayenera kuphatikizidwa ndi njira zokhala ndi ayodini komanso kugwiritsidwa ntchito maphunziro a radiopaque. Musanayambe kupanga zodzionetsera zomwe zimafuna kuyambitsa mankhwala m'thupi la wodwalayo, ndikofunikira kusiya kugwiritsa ntchito metformin m'masiku awiri. Patatha masiku awiri atatha kafukufuku, ntchito ya impso imayang'aniridwa, pambuyo pake maphunzirowo amayambiranso.

Ngati lactic acidosis imayamba ndi mankhwala osokoneza bongo, muyenera kusiya kugwiritsa ntchito mankhwalawa.

Osavomerezeka kuphatikiza

Sikulimbikitsidwa kuphatikiza kugwiritsa ntchito metformin ndi zakumwa zoledzeretsa, zakudya zama calorie otsika, mankhwala omwe amaphatikizapo mowa wa ethyl.

Kuphatikiza komwe kumafunikira kusamala

Kusamalidwa kwapadera kuyenera kumwedwa kuphatikiza Glucophage ndi izi:

1. Danazole - kugwiritsa ntchito kuphatikiza kumatha kuyambitsa kuchepa kwa magazi m'thupi. Kusintha kwa mankhwala a metformin ngati kuli kotheka, kugwiritsa ntchito munthawi yomweyo.
2. Chlorpromazine - ingalepheretse insulin kutulutsa, imachulukitsa shuga.
3. GCS - kukweza shuga m'magazi, kungayambitse ketosis.
4. Loop okodzetsa - kuphatikiza ndi metformin kumawonjezera chiopsezo cha mapangidwe a lactate.
5. Beta-adrenergic agonists - kuonjezera glycemia.
6. ACE zoletsa - chifukwa hypoglycemia.
7. Nifedipine - imathandizira kuyamwa kwa metformin ndikuwonjezera kuyika kwake kwakukulu m'magazi.

Glucophage imafuna kusamala kwambiri ikaphatikizidwa ndi mankhwala ena.

Analogi

Mafuta a mankhwalawa akuphatikizapo:

• Bagomet;
• Glycometer;
• Glucovin;
• Glumet;
• Dianormet;
• Diaformin;
• Metformin;
• Siofor;
• Panfort;
• Tefor;
• Zucronorm;
• Amnorm.

Kodi pali kusiyana kotani pakati pa Glucophage ndi Glucophage kutalika 750?

Kusiyana kwakukulu pakati pa mawonekedwe a glucophage nthawi yayitali ndi kutalika kwa chochitikacho. Kuyamwa kwa Metformin kumayamba pang'onopang'ono, komwe kumapangitsa kuti ikhalebe nthawi yayitali.

Kupita kwina mankhwala

Kodi ndingagule popanda kulandira mankhwala?

Mankhwala amaperekedwa ndi mankhwala.

Mtengo wa Glucofage 750

Mtengo wa ndalama zimadalira malo ogula.

Zosungidwa zamankhwala

Sungani pa kutentha kosaposa + 25 ° C kuchokera kwa ana.

Tsiku lotha ntchito

Mankhwalawa amatha kugwiritsidwa ntchito patatha zaka zitatu kuyambira tsiku lomwe wamasulidwa. Kugwiritsanso ntchito sikulimbikitsidwa.

Ndemanga ya Glucofage 750

Madokotala

Pavel Samarsky, endocrinologist, Moscow.

Mwa mankhwala ena ofanana, Glucophage samasiyana kwambiri. Mankhwala wokhazikika omwe ali ndi metformin, omwe ali ambiri pamsika. Kwa gulu lake lamtengo, ndilothandiza, odwala samangodandaula za zoyipa.

Muzochita zake, adagwiritsa ntchito mawonekedwe onse komanso nthawi yayitali. Kuphatikiza chida ichi ndi Insulin ndi mankhwala ena. Glucophage imagwira bwino ntchito kuti ikulimbikitsidwe kwa anzawo, koma pali mankhwala omwe amadziwonetsa bwino. Koma nayi funso m'dziko la zopanga ndi mtengo.

Lydia Kozlova, endocrinologist, Khabarovsk.

Mankhwalawa ndi oyenera kwa anthu odwala matenda ashuga. Pazaka zonse zomwe akuchita, nthawi zambiri ndapeza azimayi omwe akuyesera kuti athetse thupi. Anthu safuna kuti amvetsetse kuti mankhwalawa sanapangidwe chifukwa cha izi, koma kuchepetsa thupi, munthu atha kunena, ndizotsatira zoyipa zake.

Osadzisilira. Metformin si goji zipatso, imathanso kukhudza thanzi. Nthawi yomweyo adabweretsa msungwana wokhala ndi lactic acidic chikoma. Ndinafuna kuchepetsa thupi, koma ndinali ndi poyizoni wa thupi lonse komanso zovuta za chiwindi kwa moyo. Eya, zomwe zidakwanitsa kupopa. Pali lingaliro limodzi lokha: ngati mukufuna kuchepa thupi, dziyang'anireni nokha, osayang'ana makapu amatsenga ndi mapiritsi.

Chochita chimasungidwa pa kutentha kosaposa + 25 ° C m'malo osavomerezeka ndi ana.

Odwala

Denis, wazaka 43, Arkhangelsk.

Ndimatenga Glucophage pamalangizo a dokotala. Ndimakonda mankhwalawa chifukwa samayambitsa zotsatira zoyipa ngati atagwiritsidwa ntchito moyenera, ndipo mtengo wake ndi wabwino.

Zimathandizira kuyang'anira shuga. Poyamba, adayesetsa kuthana ndi matendawa ndikudya, adachita masewera olimbitsa thupi kuti achepetse thupi. Zinthu zinangokulirabe mpaka dokotala atamuuza Glucophage. Ndimakhala moyo wathunthu ndi iye. Muyenera kuwonetsa kuti mukaonane ndi dokotala nthawi ndi nthawi, koma ndi matenda ashuga, nthabwalazi sizabwino. Tsatirani thanzi lanu kuti musamwe mapiritsi pambuyo pake.

Zhanna, wazaka 56, Izhevsk.

Pafupifupi zaka 5 zapitazo ndidazindikira kuti ndikukula kwambiri. Kwa chaka 25 mapaundi owonjezera. Poyamba ndidapita kwa asing'anga, omwe adandilangiza kuti ndikaonane ndi dokotala. Nditatha kuyesa, ndidazindikira kuti ndili ndi matenda ashuga.

Sindinataye mtima, chifukwa ndikudziwa kuti ngakhale matendawa ndi oopsa, mutha kukhala ndi moyo. Adotolo adamuuza Glyukofazh, natenga mulingo. Ndikupitiliza kuigwiritsa ntchito pafupifupi zaka 4. Ankapumira pokhapokha adokotala akamalankhula. Ndimayesetsa kuyang'anira thanzi langa, ndimayesa mayeso nthawi zonse. Mankhwalawa amakuthandizani ngati mutsatira bwino malangizo a akatswiri. Chipangizocho ndi chabwino, sindinazindikire zotsatirazi pakugwiritsa ntchito. Chinthu chachikulu sikuti muzingoganiza nokha.

Sikulimbikitsidwa kuphatikiza kugwiritsa ntchito metformin ndi zakumwa zoledzeretsa.

Kuchepetsa thupi

Anna, wazaka 27, Moscow.

Kwa zaka zochepa ndayesera njira zambiri zochepetsera kunenepa. Ndipo ndinakhala pamadzi ndi maapulo, ndipo kwa milungu yonse ndinadya chakudya chimodzi. Muvi pamakala womwe udagwa kwakanthawi kochepa, kenako nkubwereranso ku chizolowezi chomwe mukuchidziwa.

Ndidamva kwa bwenzi kuti mutha kuchepetsa thupi potenga metformin. Ndinayamba kumwa Glucophage, nditapambana mayeso ndipo ndidakumana ndi dokotala. Ndinkamwa mapiritsi kwa masiku 20, nthawi yomweyo ndinali kuchita masewera olimbitsa thupi komanso kuyesera kudya chakudya chopatsa thanzi. Pa kosi yoyamba ndinataya pafupifupi 10 kg.

Atapumula, anabwereza maphunzirowo. Wina kusiya 12 kg. Ndine wokhutira ndi zotsatira zake. Tsopano chinthu chachikulu ndichakuti mukhale wonenepa.