Amoxicillin ali ndi bactericidal kwambiri. Amagwiritsidwa ntchito pochiza matenda. Amoxicillin ufa adapangira kuyimitsidwa. Nthawi zina odwala amatcha mitundu yomwe ilibe mankhwalawo (kuyimitsidwa kogwira sikuchitika).
Mitundu yomwe ilipo ndi kapangidwe kake
Pali mitundu ingapo yayikulu:
- ufa woyimitsidwa;
- mapiritsi
- magule;
- makapisozi.
Amoxicillin ali ndi bactericidal kwambiri. Amagwiritsidwa ntchito pochiza matenda.
Ufa umapangidwira kukonzekera kuyimitsidwa kwapadera. Izi zitha kukhala jakisoni kapena njira ya kulowetsamo.
Ufa uli ndi mtundu woyera, kuwala kwake wachikasu kumaloledwa. Zinthu zogwira ntchito ndi amoxicillin sodium ndi clavulanic acid. Ufa umatha kukhala ndi 0,5 kapena 1.0 g wa amoxicillin ndi 0,1-0.2 g wa asidi.
Amapezeka m'mabotolo opangidwa ndi zida zopangira ma polima. Bokosi la makatoni lili ndi botolo 1 ndi malangizo ogwiritsira ntchito. Katemera amaphatikiza mabotolo 10.
Dzinalo Losayenerana
INN: Amoxicillin.
ATX
Code ya ATX: J01CR02.
Zotsatira za pharmacological
Mankhwala ndi a antibacterial mankhwala a penicillin. Ndiwophatikizika kwapadera kwa penicillin ndi zoletsa zamtundu wa beta-lactamase. Zotsatira zimatheka chifukwa cha kuphatikiza kwa zigawo zikuluzikulu: clavulanic acid ndi amoxicillin.
Mphamvu ya bactericidal imatheka mwa kulepheretsa kaphatikizidwe kamakoma ka mabakiteriya a tizilombo.
Zikuwonetsa kuyendera bwino pokhudzana ndi aerobic gram-negative ndi gram-virus, kwa anaerobes ambiri.
Clavulanic acid imalepheretsa kaphatikizidwe ka beta-lactamases ena. Amakhala ndi kutentha kwakukulu kwa ma penicillinases.
Pharmacokinetics
Zonsezi zomwe zimagwira ntchito zimatengedwa mwachangu ndikugawika bwino minofu yonse ndi ziwalo zonse. Amoxicillin imatha kupezeka mu madzi a synovial, minofu yam'mimba, chikhodzodzo cha ndulu, chiwindi ndi gland ya prostate. Clavulanic acid imalowa m'mapapu, kuthira kwa pleural, khutu lapakati, kuwonjezera, mu chiberekero ndi zomwe zimagwira.
Bioavailability komanso kumangiriza kuzinthu zomanga thupi ndizochepa. Amapangidwa makamaka mu chiwindi. Hafu ya moyo ili pafupifupi maola awiri. Chiyeso chachikulu cha plasma chimafikiridwa patangopita mphindi zochepa mankhwala atalowa m'magazi.
Imafukusidwa pambuyo pake posinthidwa ndi impso mu mawonekedwe osasinthika komanso monga ma metabolites ena a clavulanic acid. Kuchotsera kwathunthu maola 6 mutatha kukhazikitsa. Kuchuluka kwa zinthu zakonzedwa kumayendetsedwa ndi impso, koma zina zimathiridwa kudzera m'mapapu ndi matumbo. Izi zimatsimikiziridwa ndi kuyesa kwa mkodzo.
Zomwe zimathandiza amoxicillin
Amagwiritsidwa ntchito pochiza matenda opatsirana komanso otupa omwe amayamba chifukwa chazomwe zimayambitsa mwachindunji mabakiteriya okhala ndi chidwi cha tizilombo toyambitsa matenda.
Zizindikiro zazikulu zogwiritsidwa ntchito:
- matenda a chapamwamba kupuma thirakiti - sinusitis, otitis media, tonsillitis, pharyngitis;
- matenda a m'munsi kupuma ziwalo - bronchitis, chibayo;
- matenda a genitourinary dongosolo - pyelonephritis, cystitis, prostatitis, urethritis, gonorrhea;
- chifuwa chachikulu
- matenda a gynecological - salpingitis, cervicitis, endometritis, vaginitis;
- zotupa zapakhungu ndi zotupa - impetigo, erysipelas, abscess, phlegmon, dermatoses zosiyanasiyana ndi leptospirosis;
- matenda opatsirana mu minyewa yolumikizana ndi mafupa;
- zotupa za biliary thirakiti - cholangitis, cholecystitis;
- matenda omwe amabwera pambuyo pakuchitidwa opaleshoni.
Ndi matenda ashuga
Mtundu wachiwiri wa matenda ashuga, Mankhwala othandizira angagwiritsidwe ntchito. Mulibe shuga. Koma munthawi ya chithandizo, ndikofunikira kuchita mayeso kuti muwone kusintha kwa kuchuluka kwa shuga m'magazi. Mlingo wa mankhwalawa umaperekedwa kuti ukhale wocheperako pofuna kupewa kukhumudwa.
Contraindication
Pali zochitika zam'magazi zomwe ntchito ndizoletsedwa:
- Hypersensitivity mankhwala opanga maantibayotiki;
- tsankho la cephalosporins;
- kuphwanya kosalekeza kwa chiwindi ntchito;
- jaundice yolepheretsa, yomwe imatha kugwiritsa ntchito mankhwalawa;
- matenda mononucleosis.
Momwe mungatenge Amoxicillin
Kukonzekera mayankho a jekeseni wamkati, zomwe zili mu vial zimasungunuka mu 10 kapena 20 ml ya madzi a jekeseni. Zimatengera muyeso wa zomwe zimapezeka mu ufa. Mankhwalawa amaperekedwa kudzera m'mitseko, pang'onopang'ono. Ndondomeko amatenga pafupifupi 3 mphindi.
Kuti akonze yankho la kulowetsedwa kwa mtsempha, ufa umapukusidwa mu 50 kapena 100 ml ya kulowetsedwa. Kutalika kwa kulowetsedwa kuyenera kukhala pafupifupi theka la ola.
Akuluakulu ndi ana omwe ali ndi zaka 12 zakubadwa amamulembera mankhwala aliwonse pakatha maola 8 aliwonse. Ngati nthendayo ikukula kwambiri, kusinthana pakati pa jakisoni kumachepetsedwa mpaka maola 6. Mulingo waukulu wa akuluakulu sayenera kupitirira 6 g wa ufa patsiku.
Kwa mwana wosakwana zaka 12, mlingo umasankhidwa payekha kutengera kulemera kwa thupi. Chokwanira chovomerezeka sichikhala choposa 250 mg mukamamwa mankhwalawa mkati mwa piritsi.
Musanadye kapena musanadye
Kudya mothandizirana sikukhudza kuperewera kwa mankhwalawa. Ngati mumadya zakudya zamafuta ambiri, mayamwidwe amachepetsa pang'ono.
Masiku angati kumwa
Chithandizo chimachitidwa osaposa masiku 14 popanda kuwunikiranso mkhalidwe wa wodwalayo. Kutalika kudzadalira msinkhu ndi kulemera, mkhalidwe wa impso.
Zotsatira zoyipa za Amoxicillin
Mukamwa maantibayotiki, mumakumana ndi mavuto osiyanasiyana. Amatha kukhudza ziwalo zonse ndi machitidwe.
Matumbo
Kuchokera m'matumbo am'mimba, kusintha kwa dyspeptic kumawonedwa. Kusanza kwambiri komanso kusanza, kutsegula m'mimba. Nthawi zambiri colitis imayamba.
Pakati mantha dongosolo
Chizungulire komanso kupweteka kwamutu kosalekeza kumawonedwa. Mwina kukula kwa zopweteka. Paresthesia ndi kugwedeza kumawonedwa.
Kuchokera ku kupuma
Kupuma kovuta. Izi zimachitika chifukwa cha kupindika m'malo opumira m'malo mwa chitukuko cha edema ya Quincke kapena kugwedezeka kwa anaphylactic.
Kuchokera pamtima
Kaonedwe kochepa. Amadziwonetsa kusintha kwakukulu pamagazi, ngakhale tachycardia ndi arrhasmia zimachitika kawirikawiri.
Matupi omaliza
Ndizofala. Ndi tsankho, angioedema imatha kupanga. Zotupa za pakhungu zimawoneka zokongola kwambiri. Amayamba erythema multiforme, urticaria. Allergic vasculitis akuti.
Kuphatikiza apo, impso zimavutika. Crystalluria ndi nephritis zimawonedwa. Kumbali ya impso, jaundice wodwala ndi chiwindi amatha kuchitika.
Malangizo apadera
Musanayambe, muyenera kutola anamnesis ndikuwona ngati pali zovuta zomwe zimayambitsa maantibayotiki. Simungathe kukupatsani mankhwala ngati mukukayikira kuti akupatsirana mononucleosis.
Mosamala, mankhwalawa amagwiritsidwa ntchito ngati matenda a impso ndi chiwindi.
Momwe mungaperekere ana
Mankhwala nthawi zambiri amagwiritsidwa ntchito kuubwana. Mlingo amawerengedwa potengera kulemera kwa wodwala pang'ono. Ngati ndi kotheka, mlingo umatha kuchepetsedwa pang'ono.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Ndi koletsedwa kumwa maantibayotiki pakubala kwa mwana komanso pakubala.
Zinthu zomwe zimagwira zimalowa bwino kudzera mu zotchinga za placenta ndikukhala ndi teratogenic ndi embyogenic kwambiri pa mwana wosabadwayo.
Pankhaniyi, zovuta zambiri za intrauterine kukula kwa mwana wosabadwayo zimapangidwa.
Mankhwala amapatsanso mkaka wa m'mawere. Ngati chithandizo chikufunika, muyenera kusiya kuyamwitsa nthawi ino.
Bongo
Pankhani ya bongo mwangozi, zosatheka dyspeptic zizindikiro zitha kuchitika, kuwonjezera, kusokonezeka mu madzi osankhidwa a electrolyte. Crystalluria nthawi zambiri imayamba, zomwe zimatsogolera kuoneka ngati kulephera kwa impso.
Chithandizo cha mankhwalawa chimangokhala chisonyezo. Detoxification chithandizo ndi kukonza kwa koyenera kwamadzi-electrolyte kumachitika. Njira ya hemodialysis imathandizira kuchotsa kwathunthu poizoni.
Kuchita ndi mankhwala ena
Synergism imachitika ndikugwiritsa ntchito nthawi yomweyo ndi mankhwala a bactericidal. Izi zimaphatikizapo aminoglycosides, potaziyamu clavulanates, cephalosporins ndi rifampicin. Macrolides, lincosamines, sulfonamides ndi tetracyclines ali ndi zotsutsana.
Kugwiritsa ntchito kosagwiritsa ntchito ma anticoagulants kumachulukitsidwa ndikumakanikizira microflora yamatumbo komanso kaphatikizidwe ka vitamini K.
Zochita zapafupifupi njira zonse zakulera zamkamwa zimachepa.
Ma diuretics, mankhwala osapweteka a antiidal ndi antioxular secretion blockular amachititsa kuti azikhala ndi zinthu zambiri mumkodzo ndi magazi.
Pogwiritsa ntchito limodzi ndi methotrexate, kawopsedwe kameneka kamawonjezera.
Mankhwala, sigwirizana ndi aminoglycosides. Mankhwala a chifuwa chachikulu, matenda a Mantoux amayenera kuchitidwa nthawi ndi nthawi.
Kuyenderana ndi mowa
Osalumikizana ndi mowa. Izi zimachepetsa mayamwidwe ndikuchepetsa mphamvu, zimathandizira kuwonjezeka kwa zizindikiro za kuledzera ndikuwonongeka kwa dongosolo lamanjenje lamkati.
Analogi
Pali mitundu ingapo ya mankhwala:
- Amosin;
- Ecobol;
- Amoxicar;
- Flemoxin Solutab;
- Amoxiclav;
- Carbapenemam.
Kupita kwina mankhwala
Mutha kugula mankhwala kumalo ogulitsa mankhwala pokhapokha mutapereka mankhwala kuchokera kwa dokotala.
Mtengo
Mtengo wa mankhwalawa umatengera kuchuluka kwa mabotolo omwe ali mumapaketi ndi m'mayendedwe a pharmacy. Pafupifupi, mtengo wake umachokera ku ma ruble 140.
Zosungidwa zamankhwala
Mutha kusunga mankhwalawo pamtunda wosaposa 15 ° C. Tetezani ku dzuwa. Pewani kwa ana aang'ono.
Tsiku lotha ntchito
Ndi zaka 2 kuyambira tsiku lopangira mankhwalawa, zomwe ziyenera kuwonetsedwa pazomwe zimapangidwira koyambirira.
Amoxiclav ndi analogue ya mankhwala Amoxicillin.
Wopanga
Kampani yopanga: OJSC "Krasfarma" Russia.
Ndemanga
Alexandra, wazaka 32, Penza: "Amoxicillin yekha ndi amene adathandiza polimbana ndi matenda opuma. Ndidamva kutulutsa kwamawa tsiku lotsatira. Sikuti zomwe zidandichitikira.
Semen, wazaka 40, Tula: "Adapereka mankhwala ochizira chibayo. Koma sindinathe kuthana nawo awa. Kutulutsa mkamwa ndi m'mimba kunayamba.
Ludmila, wazaka 27, ku Moscow: "Posachedwa ndinali ndi makanema otitisiti apamwamba. Talimbikitsana omwe adagonja ndi Amoxicillin. Nditamva izi nthawi yomweyo. Oponya anzawo sanabweretse vuto lililonse.