Momwe mungagwiritsire ntchito mankhwala Glyformin Prolong?

Gliformin Prolong ndi mankhwala omwe amagwiritsidwa ntchito pochiza matenda amtundu wa 2 shuga.

Dzinalo Losayenerana

Metformin.

ATX

Code ya ATX: A10BA02.

Gliformin Prolong ndi mankhwala omwe amagwiritsidwa ntchito pochiza matenda amtundu wa 2 shuga.

Kutulutsa mafomu ndi kapangidwe kake

Mankhwalawa ali ngati mapiritsi. Makapisozi amaphatikizidwa mumafilimu ndipo amakhala ndi mphamvu yayitali.

Mtundu wa chigobachi umasiyana wachikasu mpaka wachikasu. Zomwe zili mkati zimayera ndi timiyala tating'ono tachikasu. Piritsi ili ndi mawonekedwe a biconvex.

Chofunikira chachikulu ndi metformin hydrochloride. Mankhwalawa ali ndi zigawo zothandiza:

• methyl acrylate ndi ethyl acrylate ngati Copolymers;
• hypromellose;
• ma cellcose a microcrystalline;
• silicon dioxide.

Kuphatikizika kwa chipolalachi kumaphatikizapo talc, glycerol, utoto wa chakudya. Mapiritsi ali ndi zitini za pulasitiki kapena mabotolo a 30 kapena 60 ma PC. Phukusi lakunja lopangidwa ndi makatoni.

Mankhwalawa ali ngati mapiritsi. Makapisozi amaphatikizidwa mumafilimu ndipo amakhala ndi mphamvu yayitali.

Chofunikira chachikulu ndi metformin hydrochloride.

Glyformin amathandiza kuchepetsa kuchuluka kwa shuga m'magazi am'magazi.

Zotsatira za pharmacological

Gawo lalikulu limalepheretsa gluconeogeneis ndipo limaletsa mapangidwe a mafuta acids. Kukula kwa lipid peroxidation kumachepa. Zimathandiza kuchepetsa plasma glucose.

Kuzindikira kwa zotumphukira za insulin zolandilira kumawonjezereka ndi mankhwala.

Zisakhudze insulin. Gawo lalikulu limasintha ma pharmacodynamics a insulin yaulere, komanso limathandizira kayendedwe ka ma cell membrane.

Metformin imathandizira kaphatikizidwe ka glycogen kwinaku ikuchepetsa kuyamwa kwa glucose m'matumbo.

Chosakaniza chophatikizacho chimakonza michere ya magazi.

Kuchuluka kwa triglycerides, mafuta okwanira komanso osakwaniritsidwa amachepetsa.

Poyerekeza ndi kumbuyo kwa kumwa mankhwalawo, kulemera kwa wodwalayo kumakhazikika ndikuyamba kuchepa pang'onopang'ono.

Pharmacokinetics

Mukamwetsa, mankhwalawa amamweka m'matumbo pang'onopang'ono. Kuzindikira kwakukulu kumatheka patadutsa maola awiri atatha kumwa mapiritsi. Bioavailability ndi 60%. Zinthu zomwe sizikugwidwa sizigwidwa ndi plasma albin ndipo zimatengedwa mwachangu ndi maselo amthupi. Mankhwalawa amaphatikizidwa kwambiri mu minyewa ya impso, chiwindi ndi mavu gasi.

Osapukusidwa mu chiwindi. Amawonetsedwa osasinthika kudzera mu pulogalamu ya excretory. Hafu ya moyo wa glyformin wautali ndi kuyambira 2 mpaka 6 maola.

Zizindikiro zogwiritsidwa ntchito

Metformin imapangidwira zochizira odwala osagwiritsa ntchito insulin omwe amadalira shuga omwe alibe chakudya chokwanira komanso kuchita masewera olimbitsa thupi mwa odwala onenepa kwambiri.

Akuluakulu, amagwiritsidwa ntchito mosiyana komanso mogwirizana ndi ena othandizira a hypoglycemic.

Poyerekeza ndi kumbuyo kwa kumwa mankhwalawo, kulemera kwa wodwalayo kumakhazikika ndikuyamba kuchepa pang'onopang'ono.

Mukamwetsa, mankhwalawa amamweka m'matumbo pang'onopang'ono. Kuzindikira kwakukulu kumatheka patatha maola awiri pambuyo pa makonzedwe.

Akuluakulu, mankhwalawa amagwiritsidwa ntchito pokhapokha komanso osagwirizana ndi ena othandizira ena.

Mwa ana opitirira zaka 10, Gliformin amatha kugwiritsidwa ntchito ali okha kapena osakanikirana ndi insulin.

Mu ana opitirira zaka 10, amatha kugwiritsidwa ntchito mosiyana komanso kuphatikizidwa ndi insulin.

Contraindication

Contraindra wa mankhwala akusonyezedwa malangizo ntchito:

• pachimake kapena matenda acidosis;
• matenda ashuga ketoacidosis;
• matenda a shuga kapena matenda opatsirana;
• matenda oopsa;
• ozizira
• kutopa kapena kutopa kwa thupi;
• kukanika kwa aimpso ndi kuchepa kwa kuchuluka kwa aimpso mpaka 60 ml mphindi imodzi kapena kuchepera;
• kulephera kwa mtima kapena kuponderezana kwapanja;
• matenda ena limodzi ndi mpweya kufa ndi maselo;
• pachimake ethanol poyizoni;
• uchidakwa wambiri;
• kugwiritsidwa ntchito kwa ayodini wokhala ndi kusiyana kwa radiology kapena kuyerekezera kwamitsempha yamagazi, chikhodzodzo ndulu ndi kwamikodzo.
• Hypersensitivity payekha pazinthu zazikulu kapena zothandiza za mankhwalawa.

Ndi chisamaliro

Odwala achikulire osaposa zaka 60 omwe amakhala ndi chiwopsezo chachikulu chokhala ndi chiopsezo chokhala ndi lactic acidosis.

Contraindication kwa mankhwala, pachimake kapena matenda acidosis akuwonetsedwa.

Gliformin amaletsedwa chifukwa cholephera mtima.

Ndi chimfine, kumwa mankhwalawa osavomerezeka.

Mukamamwa mankhwalawa odwala opitilira zaka zopitilira 60, akumana ndi zovuta zolimbitsa thupi, chiopsezo chokhala ndi lactic acidosis ndiwokwera.

Mukamayamwa, mutha kugwiritsa ntchito mankhwalawa moyang'aniridwa ndi dokotala.

Mukamayamwa, mutha kugwiritsa ntchito mankhwalawa moyang'aniridwa ndi dokotala.

Momwe mungatenge Glyformin Prolong

Mapiritsi amatengedwa pakamwa pakudya kapena atatha kudya ndi madzi pang'ono.

Ndi matenda ashuga

Pa monotherapy akuluakulu, muyeso woyambirira wa mankhwala amkamwa kamodzi ndi 500 mg. Chiwerengero cha madyerero patsiku ndi kuyambira 1 mpaka 3.

Mlingo wololedwa wambiri ndi 2 g patsiku. Mlingo wa tsiku ndi tsiku wa mankhwalawa amagawidwa pawiri.

Mlingo umatuluka pang'onopang'ono milungu ingapo.

Kuchuluka kwa shuga m'magazi kumayang'aniridwa pogwiritsa ntchito mayeso, kutengera chizindikiro, mlingo umasinthidwa.

Mapiritsi amatengedwa pakamwa pakudya kapena atatha kudya ndi madzi pang'ono.

Zotsatira zoyipa

Mwa ana ndi akulu, mavuto omwewo amachitika mukamagwiritsa ntchito mankhwalawa.

Matumbo

Zotsatira zoyipa zam'mimba zimayang'aniridwa sabata yoyamba ya mankhwala, kenako. Zitha kukhala:

• nseru
• kutentha kwa mtima;
• chisangalalo;
• kusanza kapena kutsegula m'mimba;
• kupweteka kwam'mimba.

Nthawi zina, mankhwalawa amayamba.

Hematopoietic ziwalo

Megaloblastic anemia yomwe imalumikizidwa ndi matenda opatsirana a vitamini b12 imatha kuyamba.

Zotsatira zoyipa zam'mimba (mwachitsanzo, nseru) zimawonedwa sabata yoyamba ya mankhwala, kenako kumwalira.

Pogwiritsa ntchito kwa nthawi yayitali a Gliformin, vuto la vitamini b12 lingayambike.

A zotsatira zoyipa za mankhwalawa ndi hypoglycemia, chifukwa chogwiritsa ntchito njira yolakwika ya mankhwalawa.

Kuchokera kumbali ya kagayidwe

Pali chiopsezo cha lactic acidosis. Pogwiritsa ntchito nthawi yayitali, vuto la vitamini b12 limatha kukula.

Kuchokera ku genitourinary system

Kuchokera pazotsatira zoyipa za dongosolo silinakhazikike.

Dongosolo la Endocrine

Hypoglycemia yoyambitsidwa ndi kugwiritsa ntchito mankhwala olakwika a mankhwalawo.

Matupi omaliza

Nthawi zambiri, zimachitika pakhungu: redness, zidzolo, kuyabwa, matupi awo sagwirizana.

Zokhudza mphamvu pakuwongolera njira

Mankhwalawa sasokoneza mitsempha. Kuyendetsa kumaloledwa nthawi yovomerezeka.

Nthawi zambiri, mukamamwa mankhwalawa, zimachitika pakhungu pakhungu.

Pa chithandizo, kuyendetsa kumaloledwa.

Pa nthawi yoyembekezera, mankhwalawa ali osavomerezeka.

Malangizo apadera

Mlingo umasinthidwa ndikofunikira osaposa nthawi 1 pa sabata. Akaphatikizidwa ndi insulin mwa ana, kuwongolera kwa madokotala kumafunikira kupewa hypoglycemia.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Matenda a shuga ophatikizika amakhudza chitukuko cha kusokonezeka kwa chiberekero. Pa nthawi yoyembekezera, mankhwalawa ali osavomerezeka. Mukamayamwitsa, wothandizira wa hypoglycemic amapatsidwa mosamala.

Kupereka glyformin kutalika kwa ana

Osagwiritsidwa ntchito kuchitira ana osakwana zaka 10.

Gwiritsani ntchito mu ukalamba

Odwala omwe ali ndi zaka zopitilira 60 ali pachiwopsezo chachikulu chotenga acidosis, chifukwa chake, kuyang'anira kwa adokotala ndikofunikira.

The ntchito aimpso kuwonongeka

Ngati wodwala walephera kulephera kwa impso, mankhwalawa sagwiritsidwa ntchito.

Ngati wodwala walephera kulephera kwa impso, mankhwalawa sagwiritsidwa ntchito.

Gwiritsani ntchito ntchito yolakwika ya chiwindi

Ndi kulephera kwa chiwindi, amaloledwa kugwiritsa ntchito mosamala, chifukwa gawo lalikulu silimapangidwa ndi maselo a chiwindi.

Bongo

Ndi mlingo wambiri wowonjezera, mankhwalawa amadziunjikira impso. Lactic acidosis imayamba. Zotsatira za Lethal ndizotheka. Zizindikiro zotsatirazi zadziwika:

• kuchepa kwakukulu kutentha kwa thupi;
• kusanza
• kupweteka m'mimba;
• kupweteka kwa minofu ndi molumikizana;
• ochepa hypotension limodzi ndi kuchepa kwa kugunda kwa mtima;
• kupumira msanga.

Ndi kuwonjezeka kwa lactic acid m'magazi, chizungulire, kukomoka, ndi chikomokere zimawonedwa.

Ngati mankhwala osokoneza bongo amakayikiridwa, chithandizo chamankhwala chitha. Wodwala amayenera kupita kuchipatala posachedwa.

Ndi Mlingo wambiri wa mankhwala, lactic acidosis imayamba. Kukomoka kumatha kuchitika.

Pankhani ya bongo, ochepa hypotension amawonedwa limodzi ndi kuchepa kwa kugunda kwa mtima.

Ngati mukukayikira wodwala mopitirira muyeso, muyenera kupita naye kuchipatala posachedwa.

Hemodialysis ndi chithandizo chamankhwala zimachitika.

Kuchita ndi mankhwala ena

Mukamamwa pamodzi ndi insulin, sulfonamides, zotsatira za mankhwala a hypoglycemic zimatheka, zomwe zingayambitse kukula kwa hypoglycemia.

Pogwiritsa ntchito nthawi yomweyo ndi njira zakulera za mahomoni, mahomoni amtundu wa adrenal kapena chithokomiro, mphamvu ya mankhwala imachepa.

Loop diuretics imathandizira kutsegula kwa chinthu chachikulu, chomwe chimachepetsa mphamvu zomwe zimapangidwa.

B2-adrenergic zolimbikitsa kuwonjezera shuga.

Cimetidine amachulukitsa kuchuluka kwa lactic acid. Ndi kuphatikiza kwa mankhwalawa, chiopsezo cha acidosis ndichokwera.

Nifedipine imawonjezera mayamwa.

Pogwiritsa ntchito nthawi yomweyo ya Glformin yokhala ndi njira za kulera, mphamvu ya mankhwala imachepa.

Cimetidine amachulukitsa kuchuluka kwa lactic acid. Ndi kuphatikiza kwa mankhwalawa, chiopsezo cha acidosis ndichokwera.

Ndi koletsedwa kumwa mowa pa mankhwala.

Gawo lalikulu limafooketsa mphamvu ya mankhwala a anticoagulation.

Kuyenderana ndi mowa

Kumwa mowa nthawi yomweyo ndi mankhwalawa kumawonjezera chiopsezo cha lactic acidosis. Ndi koletsedwa kumwa mowa pa mankhwala.

Analogi

Zotsatira za mankhwalawa ndi:

• Fomu;
• Glucophage motalika;
• Gliformin Berlin Chemie;
• Ssiofor 1000;
• Bagomet;
• Metfogama.

Kodi pali kusiyana kotani pakati pa Gliformin ndi Glformin Pronge

Gliformin ndizofanizira zamankhwala zomwe zimakhala ndizifupi. Hafu ya moyo ndiyoyambira maola 1.5 mpaka 4.

Mapangidwe ofanana ndi formmetin.

Monga njira ina, mutha kusankha Glucofage Long.

Gliformin ndizofanizira zamankhwala zomwe zimakhala ndizifupi.

Migwirizano yopereka Glyformin Pronge Z Pharmacy

Mankhwalawa amaperekedwa pokhapokha ngati mwalandira mankhwala.

Mtengo Wokulira wa Glyformin

Ku Russia, mtengo wa mankhwalawa umayamba kuchokera ku ruble 200.

Zosungidwa zamankhwala

Mankhwalawa ndi a gulu B. Amaloledwa kusunga mankhwalawo pamalo amdima komanso owuma pamtunda wosaposa 25 ° C. Pewani kufikira ana.

Tsiku lotha ntchito

Mankhwalawa amaloledwa kusungidwa kwa zaka ziwiri. Tsiku lopangira likuwonetsedwa pa phukusi.

Wopanga Glattin Prolong

Mankhwalawa amapangidwa ndi Mtundu wa Mankhwala ku Republic of Belarus.

Ndemanga za Glformin Prolong

Mankhwalawa amadziwika ndi onse madokotala komanso odwala.

Madokotala

Olga Belyshova, katswiri wa zamankhwala, ku Moscow: "Mankhwalawa amapereka kuchepa kwakukhazikika kwa shuga wamagazi ndikuwongolera mkhalidwe wamaselo."

Egor Smirnov, endocrinologist, Sochi: "Mankhwala samalimbikitsidwa kuti agwiritsidwe ntchito nthawi imodzi ndi kukonzekera kwa chithokomiro, chifukwa mu vuto ili mankhwala onse awiri amachepa."

Odwala

Elena, wazaka 48, St. Petersburg "Kutenga mankhwalawa kumapereka kuchepa kwamphamvu kwa shuga m'magazi."

Oleg, wazaka 35, Syzran: "Ndinayamba kumwa mankhwalawa chaka chatha. Mkulu wa glucose amakhalanso bwino."

Kuchepetsa thupi

Ekaterina, wazaka 39: "Ndimagwiritsa ntchito mapiritsi kuwonjezera pazakudya. Kwa miyezi itatu ndidataya makilogalamu 8. Kulemera sikubwerera ndipo kumakhalabe pamlingo."

Alexandra, wazaka 28: "Ndi kuphatikiza kwa mankhwala, kudya komanso kuchita masewera olimbitsa thupi, adachepetsa thupi kuchoka pa 72 mpaka 65 kg."