Momwe mungagwiritsire ntchito Reduxin Met?

Reduxin Met ndi mankhwala ophatikiza. Zimakhudza kayendedwe kazinthu zosiyanasiyana zomwe zimalumikizana: zimasinthasintha kuchuluka kwa shuga m'thupi, kumalimbikitsa kuchepa thupi. Mankhwalawa amapangidwa mosiyanasiyana. Ndi cholandirira chawo chovuta kumapereka mphamvu zambiri poyerekeza ndi anzawo.

Dzinalo Losayenerana

Metformin + Sibutramine + Microcrystalline Cellulose

Reduxin Met ndi mankhwala ophatikiza.

ATX

A08a

Kutulutsa mafomu ndi kapangidwe kake

Mankhwalawa amapezeka m'mapiritsi ndi makapisozi. Zimaphatikizapo zinthu zosiyanasiyana zogwira ntchito. Phukusili lili ndi miyala 20 kapena 60. Chiwerengero cha makapisozi ndi 2 nthawi yotsika: 10 kapena 30 ma PC.

Mapiritsi

Mu 1 pc ili ndi 850 mg ya metformin hydrochloride. Zomwe zimapangidwira zimaphatikizanso zina:

• croscarmellose sodium;
• ma cellcose a microcrystalline;
• madzi oyeretsedwa;
• povidone K-17;
• magnesium wakuba.

Makapisozi

Mu 1 pc muli sibutramine hydrochloride monohydrate, cellcrystalline cellulose. Kuchuluka kwa zinthu zoyambirira kungakhale 10 ndi 15 mg, kuchuluka kwa cellcrystalline cellulose - 158,5 mg. Mlingo wa gawo lomaliza sasintha mukamagwiritsa ntchito ma sibutramine osiyanasiyana. Othandizira:

• titanium dioxide;
• utoto;
• gelatin.

Mankhwalawa amapezeka m'mapiritsi ndi makapisozi.

Zotsatira za pharmacological

Chilichonse mwazinthu zomwe zimapangidwa ndi mankhwala zimakhala zosiyanasiyana. Metformin hydrochloride ndi biguanide. Izi zimadziwika ndi zotsatira za hypoglycemic - ntchito yake yayikulu ndikuchepetsa kuchuluka kwa shuga m'magazi kukhala mulingo wabwinobwino. Mankhwala, izi sizikhudza kapangidwe ka insulin. Kuphatikiza apo, metformin imasintha kukoka kwa glucose komwe kumapangidwa ndi maselo amisempha. Zolemba zina zimaphatikizapo:

• kukakamiza kupanga mafuta acids;
• kutsika kwa kuchuluka kwa oxidation wamafuta;
• Kuchotsa kuphwanya kuyankha kwa thupi ku insulin, komwe kumapangitsa kuti magazi azikhala mokwanira;
• kutsitsa zomwe zili zingapo za organic zinthu: lipoproteins otsika, triglycerides;
• kubwezeretsa kapangidwe ka magazi.

Matenda a kuthamanga kwa shuga m'magazi amayamba chifukwa cha kuchuluka kwa zochita za anthu onse omata. Metformin imathandizira kuchepetsa kulemera, chifukwa imachepetsa kuyamwa kwa mafuta am'mimba ndi makoma a matumbo.

Metformin imalimbikitsa kuchepa thupi.

Gawoli limathandizira kuti matenda asokonekere (dyslipidemia), achepetse kuchuluka kwa cholesterol, otsika ochepa lipoproteins. Chifukwa cha izi, njira yopewera kulemera kwa thupi imakhazikika, ndi zakudya zosankhidwa bwino, kulemera kumatha kuchepa.

Sibutramine hydrochloride monohydrate imatulutsa zotsatira zake komanso kutenga gawo la amines (metabolites). Zotsatira zamachitidwe angapo amtundu wa sibutramine hydrochloride, monohydrate imasinthidwa kukhala zinthu zoyambira. Mothandizidwa ndi gawo ili, zochitika za adrenergic ndi chapakati cha serotonin receptors zimawonjezeka. Chifukwa cha izi, kumverera kwodzaza kumawonekera, kufunikira kwa chakudya kumachepa kwakanthawi.

Kuphatikiza apo, ma cellcose a microcrystalline amathandizira kuchepetsa thupi. Ndi enterosorbent yomwe imachotsa zizindikiro za kuledzera. Ma cellulose ali ndi zotsatira zabwino pazakudya zamagetsi.

Pharmacokinetics

The enterosorbent mu kapangidwe ka Reduxin Met sichikhudzana ndi zinthu zina zamankhwala ndipo samatengekedwa ndimatumbo a matumbo, amachotseredwa pakuyenda kwamatumbo. The bioavailability wa metformin ndi 50-60%. Izi zimalowa mwachangu mu madzi a m'magazi. Zochita zapamwamba zimafika pambuyo pa maola a 2,5. Metformin imakhala yopanda mphamvu kwenikweni. Thupi limachotsedwa mthupi pokodza. Kuthetsa theka-moyo sikudutsa maola 6.5.

Sibutramine imalowetsedwa kwambiri. Izi zimapukusidwa mwachangu. Pamwamba pazomwe zimagwira bwino zimatheka pambuyo pa maola 1.2. Zinthu zomwe zimatulutsidwa nthawi ya metabolism zimagwiranso ntchito, koma zimayamba kuchita maola 3-4 mutatha kumwa mankhwalawa. Ambiri a sibutramine amawachotseredwa mu mawonekedwe a metabolites ndi kutenga impso. Hafu ya moyo wa chinthu chosasinthika ndi ola limodzi. Zinthu zomwe zimasinthidwa zimachotsedwa maola 14 otsatira.

Zizindikiro zogwiritsidwa ntchito

Mankhwalawa amawonetsedwa kuti athetse kunenepa kwambiri kapena chizolowezi chambiri chosawerengeka cha odwala omwe ali ndi matenda a shuga 2, dyslipidemia, odwala prediabetes komanso milandu yomwe kukonzanso zakudya zopatsa thanzi limodzi ndi zolimbitsa thupi sizinapereke zotsatira zake. Chomwe chimapangitsa kudziwa mankhwalawa ndi chizindikiritso cha mafupa am'mimba - 27 kg / m² ndi apamwamba.

Mankhwalawa amamulembera kunenepa kwambiri kapena chizolowezi chambiri chosalemekeza odwala omwe ali ndi matenda a shuga a 2.

Contraindication

Pali zoletsa zambiri pakugwiritsa ntchito chida chofunsidwa:

• zochita za munthu zilizonse zomwe zimapangidwa;
• boma lokongola;
• ketoacidosis motsutsana ndi maziko opanga matenda a shuga;
• impso yolakwika ngati creatinine chilolezo chotsika 45 ml / min;
• matenda a chiwindi;
• zinthu zoyipa zomwe zimayambitsa kusokonezeka kwa chiwindi: kusanza, kutsegula m'mimba osagwirizana, zochitika zadzidzidzi zomwe zimabuka pazifukwa zosiyanasiyana, komanso matenda oopsa;
• kukanika kwa mtima: ischemia, matenda oopsa, etc;
• hypoxia ndi zinthu zina zilizonse zomwe zimapangitsa kuti izi zidziwike;
• poyizoni wa mowa;
• Hyperplasia ya Prostate minofu ya chosaopsa chikhalidwe, zomwe zimabweretsa kukodza pokodza ntchito, chifukwa, kuchuluka kwa yogwira zinthu zomwe ziyenera kuwonjezeka ndi impso zimawonjezeka;
• kusokonezeka kwa endocrine system (thyrotooticosis);
• pheochromocytoma;
• kutsekeka kotsekera glaucoma;
• lactic acidosis;
• kudalira kwamankhwala ndi mankhwala;
• kuvulala, maopareshoni, pamene mankhwala a insulin amafunikira;
• kuyesedwa kwaposachedwa kugwiritsa ntchito othandizira, ngati maola ochepera 48 adadutsa momwe ntchitoyi iliri;
• kudya tsiku lililonse osapitirira 1000 kcal;
• matenda anorex amanjenje, bulimia;
• nthano zamunthu wamanjenje;
• mavuto akulu amisala.

Contraindication ntchito mankhwalawa mkhutu aimpso ntchito.

Contraindication kugwiritsa ntchito mankhwala - chiwindi matenda.

Contraindication kugwiritsa ntchito mankhwala - mkhutu mtima ntchito (ischemia).

Contraindging pa kugwiritsa ntchito mankhwalawa ndi zakumwa zoledzeretsa.

Contraindication pakugwiritsa ntchito mankhwalawa - kusokonezeka kwa endocrine system (thyrotooticosis).

Contraindication kugwiritsa ntchito mankhwalawa - angle -otseka glaucoma.

Contraindging pa kugwiritsa ntchito mankhwalawa ndi matenda a anorexia manthaosa, bulimia.

Ndi chisamaliro

Mikhalidwe yambiri imadziwika komwe kumaloledwa kugwiritsa ntchito mankhwalawa pofunsa, koma chithandizo chamankhwala chikuchitika moyang'aniridwa ndi dokotala, kuwonjezera, kuyang'anira bwino momwe thupi limafunikira. Zotsutsana:

• aakulu kuzungulira kwa magazi;
• mbiri ya matenda am'mbuyo;
• cholelithiasis;
• matenda a m'mayendedwe limodzi ndi kukomoka, kusokonezeka kwa chikumbumtima;
• kuwonongeka kwaimpso ndi chiwindi ndi mawonekedwe ofatsa kapena olimbitsa;
• khunyu
• kutaya magazi;
• mankhwala ndi othandizira omwe amakhudza hemostasis ndi kupatsidwa zinthu za m'magazi;
• kuchuluka zolimbitsa thupi pa odwala zaka zopitilira 60.

Momwe mungatenge Reduxine Met

Mankhwalawa m'mitundu yosiyanasiyana (makapisozi, mapiritsi) amatengedwa ndi zakudya, makamaka m'mawa.

Mankhwala amatengedwa ndi zakudya, makamaka m'mawa.

Momwe mungatengere kuti muchepetse kunenepa

Mlingo woyambira pa gawo loyambirira: piritsi 1 ndi 1 kapisozi, ndipo mlingo wa sibutramine uzikhala 10 mg. Pa chithandizo, kulemera kwa thupi ndi shuga zimayang'aniridwa. Ngati vuto la wodwalayo silikuyenda bwino mkati mwa masiku 14, onjezani mlingo wa metformin 2 times, pitilizani kumwa kapisozi 1. Poterepa, kuchuluka kwa mankhwalawa m'magome kuyenera kugawidwa mu 2 Mlingo, zomwe zingachepetse chiopsezo chosagwirizana. Kuchuluka kwa metformin tsiku ndi tsiku ndi 2550 mg, kapena mapiritsi atatu.

Ngati mkati mwa masabata 4 kulemera kwa thupi sikunasinthe kwambiri, ndizovomerezeka kuti pang'onopang'ono muonjezere mlingo wa sibutramine mu zowonjezera za 15 mg / tsiku.

Ngati mankhwalawa sathandizira kuchepa thupi mkati mwa miyezi itatu, mankhwalawa amayimitsidwa.

Komanso, mankhwalawa amawonedwa ngati osagwira ntchito, kumapeto kwa maphunzirowo, kulemera kwa thupi kumawonjezanso. Potere, kugwiritsa ntchito mankhwalawa sikulimbikitsidwa.

Kumwa mankhwala a shuga

Mu mkhalidwe wa pathological uwu, amaloledwa kugwiritsa ntchito chiwembu chokwanira: 10-15 mg ya sibutramine ndi 850-1700 mg wa metformin. Mlingo wam'mawa - 1 piritsi ndi 1 kapisozi. Madzulo, ngati kuli kotheka, mutenge piritsi limodzi. Nthawi yovomerezeka yothandizira odwala matenda ashuga ndi 1 chaka. Ngati mukufuna kupitiliza maphunziro, sibutramine imathetsedwa, pambuyo pake ndi metformin yokha yomwe imatengedwa.

Zotsatira zoyipa Reduxine Met

Zizindikiro zomwe zingachitike ndi chimfinezi zimadziwika, chiopsezo chokhala ndi edema, thrombocytopenia, komanso kuwonekera kwa ululu wammbuyo kumawonjezeka.

Matumbo

Madzi am'madzi, kudzimbidwa, zotupa, kusanza, kusanza, kupweteka pamimba, kusowa kwa chiwindi, chiwindi.

Zotsatira zoyipa za Reduxine Meth zimawonetsedwa mwazizindikiro zomwe zimatha kuchitika ndi chimfine.

Zotsatira zoyipa za Reduxin Methante zimawonetsedwa mu mseru.

Zotsatira zoyipa Reduxine Meth imawonetsedwa mu mawonekedwe a ululu pamimba.

Zotsatira zoyipa za Reduxin Methante zimawonetsedwa mwa kugona.

Zotsatira zoyipa za Reduxin Meth zimawoneka ngati mutu.

Zotsatira zoyipa Reduxine Meth imawonetsedwa momwe amasinthira kugunda kwa mtima.

Zotsatira zoyipa Reduxin Meth zimawonetsedwa mwa kuyimitsidwa ndi matupi awo.

Pakati mantha dongosolo

Kukhumudwa, kugona, kusakwiya kumakula. Pali kuphwanya kukoma. Mutu, chizungulire, kuuma kwa mucous nembanemba mkamwa kumawonekera.

Kuchokera kwamikodzo

Yade mu pachimake gawo.

Kuchokera ku genitourinary system

Dysmenorrhea.

Kuchokera pamtima

Kusintha kwa kugunda kwa mtima, kuthamanga kwa magazi.

Matupi omaliza

Kuyenda, zotupa, erythema, kuchuluka kwa thukuta.

Zokhudza mphamvu pakuwongolera njira

Palibe malamulo okhwima, komabe, mankhwalawa angakhudze kwambiri kuyendetsa magalimoto. Pazifukwa izi, kusamala kuyenera kugwiritsidwa ntchito poyendetsa.

Mankhwalawa angakhudze kwambiri kuyendetsa bwino magalimoto.

Malangizo apadera

Kwa anthu azaka zopitilira 65, mankhwalawa satchulidwa.

Odwala omwe apezeka ndi matenda a shuga omwe amakhala ndi vuto la aimpso, chiwopsezo chokhala ndi lactic acidosis chimawonjezeka.

Mankhwalawa satengedwa asanachitike opareshoni. Lekani kulandira chithandizo kwa maola 48 musanachite opareshoni.

Ndi chithandizo cha nthawi yayitali chotsutsana ndi maziko a kukanika kwa impso, chilolezo cha creatinine chiyenera kuyang'aniridwa kamodzi pachaka.

Mankhwalawa amatha kugwiritsidwa ntchito pokhapokha ngati njira zosagwiritsa ntchito mankhwala zomwe zimapangitsa kuchepetsa thupi sizinapereke zotsatira zomwe mukufuna.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Chipangizocho chimaletsedwa kugwiritsa ntchito.

Kukhazikitsidwa kwa Reduxine Met kwa ana

Sikugwira ntchito mpaka zaka 18.

Mankhwala ochulukirapo a Reduxine Met

Ngati mumagwiritsa ntchito metformin yochulukirapo, chiopsezo chokhala ndi lactic acidosis imawonjezeka. Kuti apititse wodwalayo matenda oterowo, njira yochizira ndi Reduxin Met imayimitsidwa, hemodialysis imachitidwa kuchipatala.

Sibutramine kawirikawiri samakwiyitsa kukula kwa zoyipa zoyipa, komabe, nthawi zina, tachycardia, kupweteka kwa mutu ndi chizungulire zitha kuchitika, kukakamizidwa kumawonjezeka. Zizindikiro zimazimiririka ngati mumasokoneza maphunzirowo.

Sibutramine kawirikawiri samakwiyitsa kukula kwa zoyipa, koma nthawi zina, kupsinjika kumawonjezeka.

Kuchita ndi mankhwala ena

Sizoletsedwa kuphatikiza metformin ndi ma radiological kusiyanasiyana omwe ali ndi ayodini.

Mochenjera, mankhwalawa amagwiritsidwa ntchito limodzi ndi Chlorpromazine, Danazole, glucocorticosteroids, diuretics, Nifedipine, ACE inhibitors ndi beta-2-adrenergic agonists m'njira yankho la jakisoni.

Kuyenderana ndi mowa

Mankhwala amathandizira kukulitsa lactic acidosis, ngati amaphatikizidwa ndi zakumwa zoledzeretsa.

Analogi

M'malo mogwira mtima:

• Kuwala kwa Reduxin;
• Goldline Plus;
• Turboslim.

Kusiyanitsa kwa Reduxin Met kuchokera ku Reduxin

Wothandizirayo pamafunso ali ndi zinthu zitatu zogwira ntchito, zomwe zimapangitsa kuti ikhale yothandiza kwambiri kuposa ma analogu ambiri. Reduxin amadziwika ndi zinthu ziwiri zomwe zimapangidwa, sibutramine, microcrystalline cellulose amachita ngati mankhwala othandizira.

Kupita kwina mankhwala

Mankhwala omwe mumalandira.

Kodi ndingagule popanda kulandira mankhwala?

Ayi.

Mtengo wa Reduxin Met

Mtengo wapakati ndi ma ruble 3000.

Zosungidwa zamankhwala

Kutentha kwambiri m'chipindacho: + 25 ° C. Zogulitsirazi siziyenera kuwonekera pakuwala kwa dzuwa.

Tsiku lotha ntchito

Chida chimasungabe katundu kwa zaka zitatu.

Wopanga

OZONE, Russia.

Analog Reduxin Met - Kuwala kwa Reduxin.

Analog Reduxin Met - Goldline kuphatikiza.

Analog Reduxin Met - Turboslim.

Ndemanga za Reduxine Met

Madokotala

Aliluev A.A., wothandizira, wazaka 43, Krasnodar

Mankhwala amafunika kusamala mukamagwiritsa ntchito, chifukwa ali ndi contraindication ambiri. Pa mankhwala, magazi, kuthamanga, kugunda kwa mtima kumayang'aniridwa.

Pavlova O. E., wazolowera, wazaka 39, Khabarovsk

Njira yabwino yothetsera. Zimathandiza kuti muchepetse kunenepa kwambiri. Ngati mumanga zida zamagetsi molondola, mutha kupeza zotsatira zabwino.

Odwala

Anna, wazaka 37, Penza

Ndidamwa mankhwalawa kwa miyezi ingapo. Thupi silinalekerere bwino, motero maphunzirowo adayima pasadakhale.

Anastasia, wazaka 33, Bransk

Ndili ndi matenda ashuga. Ndimawona kulumpha kosalekeza - zimangowonjezeka kwambiri. Mothandizidwa ndi Reduxin, mutha kuwongolera njirayi pang'ono.

Kuchepetsa thupi

Valentina, wazaka 29, St. Petersburg

Ndinamwa mankhwalawa pamene kulemera kumawonjezeka panthawi yapakati. Dokotala adati choyamba muyenera kusiya kuyamwa, chifukwa mankhwalawa adayamba zaka 1.5. Ndidayesetsa kudya, kuchita masewera olimbitsa thupi ndipo nthawi yomweyo ndimamwa mapiritsi, makapisozi. Pambuyo pa miyezi iwiri, zotsatira zake zinali zowoneka pang'ono.

Olga, wazaka 30, Vladivostok

Munthawi yogwiritsira ntchito Reduxine, Met adathandizira thupi mothandizidwa ndi mavitamini, popeza kuti zakudya zochepa zama calorie zimayenera kuyang'aniridwa. Maphunzirowa ndi achidule kwambiri - miyezi itatu. Munthawi imeneyi, sizinali zotheka kuchepetsa kwambiri thupi, koma kusintha kwakung'ono kunali kuwonekerabe. Pakapita kanthawi ndikupitiliza kumwa mankhwalawa.