Mapiritsi a Augmentin 125: malangizo ogwiritsira ntchito

Mapiritsi a Augmentin 125 ndi othandizira antimicrobial wodziwika bwino. Mmenemo, maantibayotiki okhala ndi maantioticillin amalimbikitsidwa ndikamayambitsa clavulanic acid, yomwe imakhala ngati beta-lactamase inhibitor, pakupanga.

Dzinalo Losayenerana

INN yamankhwala awa ndi Amoxicillin ndi Clavulanic acid.

Mapiritsi a Augmentin 125 ndi othandizira antimicrobial wodziwika bwino.

ATX

Mankhwalawa ali ndi code ya ATX J01CR02.

Kupanga

Chogulitsachi chili ndi magawo awiri omwe amagwira ntchito - mawonekedwe a amohydillin (antiotic) ndi clavulanic acid mu mawonekedwe a mchere wa sodium (β-lactamase inhibitor). Mu piritsi Augmentin ndi 125 mg wa clavulanate, ndi mankhwala - 250, 500 kapena 875 mg. Kudzazidwa kwothandiza kwaperekedwa:

• silika;
• magnesium wakuba;
• sodium wowuma glycolate;
• microcellulose.

Mapiritsiwo ali ndi zokutira zoteteza gastro zopangidwa ndi hypromellose, macrogol, titanium dioxide ndi dimethicone. Amagawidwa mzidutswa 7 kapena 10. m'matumba, omwe, limodzi ndi desiccant, adasindikizidwa ndi zojambulazo. Mapiritsi 250 mg + 125 mg amadzaza zidutswa 10 zokha. Ma Plita awiri otumphukira amaikidwa m'matakadi.

Chidacho chili ndi mtundu wa amoxicillin.

Zotsatira za pharmacological

The pharmacodynamics of Augmentin imatsimikiziridwa ndi ntchito yolumikizana ya amoxicillin ndi sodium clavulanate, omwe amapezeka ngati othandizira pakapangidwe kamankhwala. Amoxicillin ndi mankhwala a penicillin opangidwa ndi gulu la β-lactam. Imalepheretsa ntchito ya puloteni ya bakiteriya, yomwe imatenga gawo pazinthu zomwe zimapangidwa ndi khoma la cell, zomwe zimayambitsa kuphedwa kwa mabakiteriya.

Kuwonekera kwa ntchito ya bactericidal ya antibayotiki ndi yotakata paliponse, koma imawonongedwa mchikakamizo cha beta-lactamases yopangidwa ndi tizilombo toyambitsa matenda. Chifukwa chake, clavulanic acid umagwiritsidwa ntchito - chinthu chofanana ndi mawonekedwe a penicillin. Imapangitsa ma enzyme ena a β-lactam, potero kukulitsa njira zosiyanasiyana za antibacterial za amoxicillin.

Augmentin amalimbana ndi tizilombo toyambitsa matenda ambiri, kuphatikizapo:

• hemophilic ndi E. coli;
• staphilo ndi streptococci;
• Salmonella
• cholera vibrio;
• chlamydia
• Shigella
• clostridia;
• Klebsiella;
• leptospira;
• Proteus
• acineto-, citro- ndi enterobacteria;
• ma bacteria;
• causative othandizira a pertussis, chibayo, anthrax, syphilis, gonorrhea.

Zida zogwira ntchito zochokera m'mimba zomwe zimayamwa zimayamwa mwachangu komanso mokwanira.

Pharmacokinetics

Zida zogwira ntchito zochokera m'mimba zomwe zimayamwa zimayamwa mwachangu komanso mokwanira. Pazambiri kuchuluka kwa amoxicillin mu madzi am'madzi amatsimikiza pambuyo maola 1-2. Imagawidwa mthupi. Amapezeka mu bile, synovia, peritoneal madzimadzi, ma manambala, minofu, zigawo zamafuta, ziwalo zam'mimba, purulent exudate, mkaka wa m'mawere.

Mankhwala amawoloka chikhazikitso, koma chotchinga chamagazi ndimakhalabe chosagonjetseka nacho. Kuyankhulana ndi mapuloteni am magazi mu antioxotic ndi pafupifupi 17%, mu inhibitor - mpaka 25%.

Amoxicillin samapangidwira bwino, chifukwa chake metabolite imagwira ntchito. Excretion ikuchitika ndi mkodzo. Codiumulanate sodium imakonzedwa mwachangu, yopukusidwa ndi impso, mapapu (mwanjira ya kaboni dayokisi) ndi ndowe.

Zisonyezero zogwiritsira ntchito mapiritsi a Augmentin 125

Mankhwalawa cholinga chake ndikuchotsa matenda omwe amabwera chifukwa cha tizilombo toyambitsa matenda. Zisonyezero zogwiritsidwa ntchito:

1. Matenda a chapamwamba kupuma dongosolo.
2. Matenda a Otorhinolaryngological, kuphatikizapo otitis sinusitis ndi pharyngotonzillitis.
3. Zilonda za bronchopulmonary: bronchitis, bronchopneumonia, chibayo.
4. Matenda amtundu wa genitourinary ndi ziwalo zoberekera, kuphatikiza cystitis, urethral syndrome ndi chinzonono.
5. Zilonda pakhungu, zigawo zamkati, mafupa ndi mafupa awo.
6. Matenda a nkhope ndi pakamwa, monga mano ndi mano ndi periodontitis.
7. Septicemia.
8. Matenda a amayi, matenda ophatikizika.

Mankhwala anagwiritsa ntchito matenda a chapamwamba kupuma dongosolo.

Mankhwalawa adapangira bronchitis.

Mankhwalawa amapangira chibayo.

Mankhwala anagwiritsa ntchito matenda a genitourinary thirakiti.

Kodi ndizotheka ndi matenda ashuga

Anthu odwala matenda ashuga amatha kumwa mankhwala monga adokotala amawayang'anira.

Contraindication

Mankhwala sangathe kugwiritsidwa ntchito ndi hypersensitivity pazochita zilizonse za mankhwala ndipo ngati pali mbiri yokhudzana ndi kugonjetsedwa kwa mankhwala a penicillin. Zotsutsa zina:

• benign lymphoblastosis;
• lymphocytic leukemia;
• chiwindi ntchito, kuphatikizapo cholestasis, kale anati ndi clavulanic acid kapena amoxicillin;
• kulephera kwaimpso (creatinine pansipa 30);
• zaka mpaka 12.

Odwala omwe ali ndi pseudomembranous colitis, komanso amayi oyembekezera komanso oyamwitsa, amafunika kuwongolera mwapadera.

Momwe mungatenge mapiritsi a Augmentin 125

Mankhwalawa sagwiritsidwa ntchito podzichiritsa nokha. Mlingo wotalikirapo komanso nthawi ya mankhwalawa imatsimikiziridwa ndi dokotala malinga ndi zomwe akuwonetsa. Ndikofunikira kuganizira kuwonongeka kwa tizilombo toyambitsa matenda, kuopsa kwa zotupa, zaka, kulemera kwa thupi komanso mkhalidwe wa impso za wodwalayo.

Piritsi lamtundu wa mankhwalawa amapangidwira achikulire ndi ana a zaka 12 zokhala ndi kulemera koposa 40 kg. Ngati mwana ali ndi zaka zosakwana 12, muyenera kumupatsa mankhwala osokoneza bongo.

Mapiritsi aledzera pamimba yopanda kanthu ndi madzi ambiri. Kuti muteteze chimbudzi, ndibwino kuti muzidya ndi chakudya, kumayambiriro kwa chakudyacho. Mankhwala ochepetsa mphamvu ya kachilombo ka mankhwalawa amagwiritsidwa ntchito pochiza zotupa zochepa. Amatengedwa panjira ya maola 8. Mu matenda oopsa, mapiritsi okhala ndi muyeso wa 500 mg + 125 mg kapena 875 mg + 125 mg amagwiritsidwa ntchito.

Njira yocheperako yocheperako ndi masiku 5.

Mlingo wotalikirapo komanso nthawi ya mankhwalawa imatsimikiziridwa ndi dokotala malinga ndi zomwe akuwonetsa.

Zotsatira zoyipa za mapiritsi a Augmentin 125

Mankhwalawa amalekeredwa bwino, koma nthawi zina zimachitika zovuta.

Matumbo

Kusanza, kusanza, kutsekula m'mimba, gastritis, stomatitis, mankhwala am'mimba, kupweteka kwam'mimba, ndi dysbiosis. Zowopsa zomwe zimakhala ndi lilime lakuda, kudetsa khungu la enamel.

Hematopoietic ziwalo

Sinthani mu zochulukitsa zizindikiro za kapangidwe ka magazi, kuchuluka kwa magazi nthawi.

Pakati mantha dongosolo

Chizungulire, migraines, kusintha kwa machitidwe, kuchepa kwa thupi, kusowa tulo, kukomoka (ndi mlingo waukulu kapena kuwonongeka kwa impso) kumawonedwa.

Kuchokera kwamikodzo

Mitsempha yamagazi nthawi zina imatuluka mkodzo, nephritis ndiyotheka, ndipo pamlingo waukulu - crystalluria.

Khungu komanso mucous nembanemba

Nthawi zambiri, odwala amakhala ndi candidiasis. Erythema yotheka, zotupa za thupi, kuyabwa, kutupa. Milandu yowonekera kwa exudate ndi necrolysis ya integument adadziwika.

Nthawi zambiri atatha Augmentin 125, odwala amakhala ndi candidiasis.

Kuchokera pamtima

Nthawi zina, magazi.

Pa mbali ya chiwindi ndi biliary thirakiti

Ntchito ya Enzymatic imatha kukula, kulephera kwa chiwindi ndi cholestasis.

Zokhudza mphamvu pakuwongolera njira

Zotsatira zosiyanasiyana mwadzidzidzi kuchokera ku dongosolo lamanjenje ndizotheka. Chifukwa chake, muyenera kusamala mukamagwira ntchito yoopsa.

Malangizo apadera

Kuwonekera kwa tizilombo tating'onoting'ono kumatha kudalira geolocation ndikusiyanasiyana munthawi, chifukwa chake tikulimbikitsidwa kuchita kusanthula koyambirira.

Chida ichi sichikugwiritsidwa ntchito pakuganiza kuti ndi mononucleosis.

Ngati thupi lonse siligwirizana, mankhwala a okosijeni ndi makonzedwe a corticosteroids angafunike.

Ndi chithandizo chotenga nthawi yayitali, muyenera kumwa madzi ambiri, muziyang'anira magazi, chiwindi, matenda a impso ndi impso. Kukondwerera kumatha kuchitika pakumwa.

Chida ichi sichikugwiritsidwa ntchito pakuganiza kuti ndi mononucleosis.

Gwiritsani ntchito mu ukalamba

Mu ntchito yachilendo ya impso ndi chiwindi, mlingo woyenera umagwiritsidwa ntchito.

Kupatsa ana

Mapiritsi sanapangidwire ana. Amatha kuledzera ndi achinyamata (kuyambira azaka 12) kugwiritsa ntchito Mlingo wachikulire ngati wodwalayo azidutsa 40 kg.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Mankhwala omwe amafunsidwawo alibe teratogenic, koma ayenera kumwedwa nthawi yayitali. Zogwira ntchito za mankhwala zimalowa mofooka mkaka (zopezeka mwanjira yamtundu). Mu makanda, izi sizimayambitsa kutsekula m'mimba; pakhala pali zochitika za candidiasis ya mucosa yamlomo. Chifukwa chake, amalimbikitsidwa ndi mankhwala othandizira kuti asokoneze kuyamwitsa.

The ntchito aimpso kuwonongeka

Ngati creatinine chilolezo ndichipamwamba kuposa 30 ml / mphindi, ndiye kuti kusintha kwa mlingo sikofunikira. Pa mfundo zochepa, kuchuluka kwa mankhwalawa kumayenera kuchepetsedwa. Mapiritsi 875 mg + 125 mg sangaperekedwe kwa odwala.

Gwiritsani ntchito ntchito yolakwika ya chiwindi

Mankhwala othandizira antioxotic amachitika moyang'aniridwa ndi dokotala. Ndikofunikira kuyang'anira momwe chiwindi chimapangidwira.

Tengani Augmentin 125 nthawi yoyembekezera iyenera kukhala njira yomaliza.

Bongo

Kuchulukitsa Mlingo womwe mumagwiritsa ntchito ndikulupika kwakanthawi kokhala ndi Mlingo wambiri kungayambitse bongo. Zizindikiro:

• kupumirana mseru, kusanza;
• kutsegula m'mimba
• kusowa kwamadzi;
• krystalluria;
• kulephera kwaimpso;
• kuwonongeka kwa chiwindi
• minofu kukokana.

Zizindikiro zoopsa zikawoneka, muyenera kuchotsa m'mimba ndikubwezeretsa madzi ndi mchere. Ngati ndi kotheka, pitani ku hemodialysis.

Kuchita ndi mankhwala ena

Mwina kuchepa kwamphamvu pakubera kwamlomo. Pogwiritsa ntchito imodzi ndi anticoagulants, kusintha kwa Mlingo womaliza kungafunike. Sipayenera kuphatikizidwa ndi allopurinol, methotrexate, probenecid.

Kuyenderana ndi mowa

Muyenera kupewa kumwa mowa.

Analogi

Mankhwalawa amapezeka osati pamapiritsi, komanso mawonekedwe a ufa, pomwe kuyimitsidwa kwamlomo kumakonzedwa. Palinso fomu ya ufa yopangidwira jakisoni. Kukonzekera kofananako:

• Panklav;
• Amoxiclav;
• Flemoklav Solutab;
• Novaklav;
• Arlet et al.

Panclave ndi mankhwala ofanana.

Amoxiclav ndi mankhwala ofanana.

Flemoklav Solutab - mankhwala ofanana.

Kupita kwina mankhwala

Ndi mankhwala.

Mtengo

Mtengo wa mapiritsi ndi 250 mg + 125 mg - kuchokera ku ma ruble 210.

Zosungidwa zamankhwala

Mankhwalawa ayenera kutetezedwa kwa ana. Amasungidwa m'malo owuma komanso amdima. Kutentha kosungira sikuyenera kupitirira + 25 ° С.

Tsiku lotha ntchito

Zaka zitatu Pambuyo potsegula phukusi - masiku 30.

Wopanga

Mankhwalawa amapangidwa ndi SmithKline Beecham PLC (United Kingdom).

Ndemanga

Mankhwalawa amalandila ndemanga zabwino.

Madokotala

Kravets K.I., wothandizira, Kazan

Wothandizila antibacterial wothandizila osiyanasiyana. Mankhwala ake oopsa amakhala ochepa, koma muyenera kuwunika momwe chiwindi chimakhalira, makamaka pamaso pa matenda a ziwalo.

Trutskevich E.A., dotolo wamano, Moscow

Mankhwala amalekeredwa bwino. Koma ziyenera kukumbukiridwa kuti maziko ake ndi mankhwala othandizira. Chifukwa chake, ndikofunikira kukhalabe ndi microflora yamatumbo, kutenga njira zoyenera.

Odwala

Anna, wazaka 19, Perm

Mapiritsi adathandizira kuthana ndi otitis media m'masiku asanu.

Eugene, wazaka 44, Ryazan

Drank Augmentin sabata limodzi ndi sinusitis. Panalibe zovuta komanso zoyipa.