Actovegin 200 ndi mankhwala osakanizidwa amachokera ku nyama. Mwazi wa ng'ombe zazing'ono unatengedwa ngati maziko a mankhwalawa pakupanga. Mankhwalawa ndi a gulu la mankhwala a metabolic omwe amakomera kugwiritsa ntchito shuga ndi metabolism ya oxygen. Kumwa mankhwalawa kumachepetsa chiopsezo chokhala ndi mpweya m'maselo am'maselo ndipo kumathandizanso kusintha kagayidwe kachakudya ka thupi.
Dzinalo Losayenerana
Actovegin. Mu Chilatini - Actovegin.
Actovegin 200 ndi mankhwala osakanizidwa amachokera ku nyama.
ATX
B06AB.
Kutulutsa mafomu ndi kapangidwe kake
Actovegin amapezeka mu mawonekedwe a jekeseni wa jekeseni komanso mawonekedwe a mapiritsi.
Mapiritsi
Pamwambapa pali chithunzi cha utoto wonyezimira wamtundu wa chikasu, wokhala ndi:
- chingamu;
- sucrose;
- povidone;
- titanium dioxide;
- phiri njuchi glycol sera;
- talc;
- macrogol 6000;
- hypromellose phthalate ndi dibasic ethyl phthalate.
Utoto wachikasu wa Quinoline ndi varnish wa aluminiyamu umapereka mfuti inayake ndikuwala. Piritsi yayikulu imakhala ndi 200 mg ya yogwira popanga magazi a ng'ombe, komanso microcrystalline cellulose, talc, magnesium stearate ndi povidone ngati mankhwala ena owonjezera. Magawo a mankhwalawo ali ndi mawonekedwe ozungulira.
Imodzi mwazomwe akutulutsa Actovegin ndi mapiritsi.
Njira Zothetsera
Njira yothetsera vutoli imakhala ndi magalasi 5 agalasi omwe ali ndi 200 mg yogwira ntchito - Actovegin concentrate, yopangidwa kuchokera ku hemato-derivative ya ng'ombe ya ng'ombe, yomasulidwa ku mankhwala a protein. Madzi osalala a jakisoni amakhala ngati chowonjezera chowonjezera.
Zotsatira za pharmacological
Actovegin ndi njira yolepheretsa kukula kwa hypoxia. Kupanga mankhwalawa kumakhala mu dialysis yamagazi am ng'ombe ndikulandira hemoderivat. Zinthu zopanda pake pazopanga zimapanga zovuta ndi mamolekyu wolemera mpaka 5000 dalton. Chithandizo choterechi ndi antihypoxant ndipo chimakhala ndi zotsatira zitatu mthupi:
- kagayidwe
- bwino microcirculation;
- neuroprotective.
Kugwiritsa ntchito mankhwalawa kumakhudza mayendedwe komanso shuga ya shuga chifukwa cha phosphoric cyclohexane oligosaccharides, omwe ali gawo la Actovegin. Kuthamangitsa kugwiritsidwa ntchito kwa glucose kumathandizira kukonza mitochondrial ntchito ya maselo, kumabweretsa kuchepa kwa kaphatikizidwe ka lactic acid kumbuyo kwa ischemia ndikuwonjezera mphamvu kagayidwe.
Actovegin ndi njira yolepheretsa kukula kwa hypoxia.
Mphamvu ya neuroprotective ya mankhwalawa imachitika chifukwa cha kulepheretsa kwa apoptosis ya maselo a mitsempha pamavuto. Kuchepetsa chiopsezo cha kufa kwa minyewa, mankhwalawa amachepetsa zochitika za beta-amyloid ndi kappa-bi, ndikuwonetsa apoptosis ndikuwongolera njira yotupa m'mitsempha ya zotumphukira zamitsempha.
Mankhwala amakhudza endothelium wa capillaryplores, sinamizidwe kachulukidwe ka michere.
Pharmacokinetics
Zotsatira zamaphunziro a zamankhwala, akatswiri sanathe kudziwa nthawi yomwe angafike nthawi yayitali yogwira ntchito m'magazi am'magazi, theka la moyo ndi njira yodutsa. Ichi ndi chifukwa kapangidwe ka hemoderivative. Popeza chinthucho chimangokhala ndi zinthu zina zomwe zimapezeka mthupi, sizingatheke kudziwa magawo enieni a pharmacokinetic. The achire zotsatira zimawonekera theka la ola pambuyo pakamwa makonzedwe ndikufika pazofunikira pambuyo maola 2-6, kutengera mawonekedwe a wodwalayo.
Pochita malonda ogulitsa, sipanakhalepo zochitika zakuchepa kwa mankhwalawa kwa odwala omwe ali ndi vuto la impso.
Pochita malonda ogulitsa, sipanakhalepo zochitika zakuchepa kwa mankhwalawa kwa odwala omwe ali ndi impso kapena hepatic.
Zomwe zimayikidwa
Mankhwala amatchulidwa ngati mbali ya zovuta mankhwala otsatirawa milandu:
- ngozi yamitsempha;
- dementia
- kufalikira kwaziphuphu;
- kuvutika kwamitsempha yamagazi m'mitsempha;
- kuchepa kwa sitiroko chifukwa cha ntchito;
- matenda ashuga polyneuropathy.
Mankhwalawa amagwiritsidwa ntchito ngati awonongera njira zamkati ndi venous komanso chifukwa cha zovuta (kukula kwa zilonda zam'mimba, vasopathy).
Contraindication
Mankhwalawa amadziwikiridwa kwa anthu omwe ali ndi chiwopsezo chowonjezereka cha zinthu za Actovegin ndi mankhwala ena a metabolic. M'pofunika kukumbukira zomwe zili mu sucrose kunja kwa mapiritsi, zomwe zimalepheretsa kayendedwe ka Actovegin kwa anthu omwe ali ndi vuto la glucose-galactose mayamwidwe kapena chibadwa chokhala ndi tsankho. Mankhwala osavomerezeka chifukwa cha kuchepa kwa sucrose ndi isomaltase.
Ndi chisamaliro
Ndikofunikira kuwongolera mkhalidwe wam'mimba wamatumbo kwa anthu omwe ali ndi vuto la mtima la 2 kapena 3 mwamphamvu. Chenjezo liyenera kuchitidwa makamaka ngati m'mapapo mwanga edema, anuria ndi oliguria. Zotsatira zochizira zitha kuchepa ndi kuchepa thupi.
Ndikofunikira kuwongolera mkhalidwe wam'mimba wamatumbo kwa anthu omwe ali ndi vuto la mtima la 2 kapena 3 mwamphamvu.
Momwe mungatenge Actovegin 200
Mapiritsi amatengedwa pakamwa musanadye. Osatafuna mankhwalawa. Mlingo umakhazikitsidwa kutengera mtundu wa matenda.
Njira yothetsera njirayi imayendetsedwa mu / mu kapena / m.
| Matendawa | Chithandizo cha mankhwala |
| Dementia | Mapiritsi 2 amatengedwa katatu patsiku kwa miyezi isanu. |
| Matenda oyamba ozungulira, kuphatikizira ndi ma pathologies omwe amaphatikizidwa ndi zovuta | Mlingo wa tsiku ndi tsiku umachokera ku 600 mpaka 1200 mg ya makonzedwe katatu patsiku. Chithandizo cha matendawa chimatha milungu isanu ndi umodzi. |
| Cerebrovascular ngozi | 5-25 ml iv yothetsera masiku 14, kenako ndikumamwa mapiritsi ndi mlingo kutengera umunthu wa wodwalayo. |
| The pachimake gawo la ischemic sitiroko. Mankhwala ndi mankhwala kwa masiku 5-7. | Mtsempha wa mtsempha wama 2000 mg patsiku. Mankhwalawa amachitika mpaka 20 infusions, kenako kusintha mapiritsi (2 mayunitsi katatu patsiku). Kutalika konse kwa mankhwalawa ndi milungu 24. |
| Peripheral angiopathy | 20-30 ml ya mankhwalawa imapukusika ndi yankho la 0.9% isotonic. Adatulutsa iv kwa mwezi. |
| Ischemic stroke | 20-50 ml ya Actovegin imasungunuka ndi 200-350 ml ya metabolism 0,9% sodium chloride kapena 5% glucose. Madontho amayikidwa sabata limodzi, kenako mlingo wa Actovegin umachepetsedwa 10-20 ml ndikuyika ngati kulowetsedwa kwa masabata awiri. Pambuyo kutha kwa mankhwala ndi yankho, amasinthira kutenga mawonekedwe a piritsi. |
| Mphamvu ya cystitis | 10 ml ya yankho limayendetsedwa mosinthana ndi maantibayotiki pamlingo wa 2 ml / min. |
| Kukonzanso Kwachangu | 10 ml ya mankhwalawa amapaka jekeseni wamkati kapena jekeseni wa 5 ml ya Actovegin. Kutengera kubwezeretsa kwa minofu, mankhwalawa amatha kutumikiridwa tsiku lililonse kapena kangapo katatu pa sabata. |
| Kuchiza ndi kupewa zotsatira za mankhwala a radiation (pakhungu ndi mucous) | 5 ml iv. |
Kumwa mankhwala a shuga
Pankhani ya matenda ashuga polyneuropathy, kulowetsedwa kwa mtsempha tsiku lililonse 2000 mg tikulimbikitsidwa. Pambuyo pa 20 omwe adangotsika, kusintha kwa pakamwa pa fomu ya Actovegin ndikofunikira. 1800 mg pa tsiku zotchulidwa ndi pafupipafupi makonzedwe 3 pa tsiku 3 mapiritsi. Kutalika kwa mankhwalawa kumasiyana kuyambira miyezi inayi mpaka isanu.
Pankhani ya matenda ashuga polyneuropathy, kulowetsedwa kwa mtsempha tsiku lililonse 2000 mg tikulimbikitsidwa.
Zotsatira zoyipa
Zotsatira zoyipa za mankhwalawa zimatha kuchitika chifukwa cha mlingo wosankhidwa mosayenera kapena kugwiritsa ntchito molakwika mankhwalawo.
Kuchokera ku minculoskeletal system
Wothandizila kagayidwe kachakudya amathanso kukhudza mozungulira metabolism, yomwe imasokoneza mayamwidwe a calcium ion. Mwa odwala odziwikiratu, chiopsezo chokhala ndi gout chimawonjezeka. Nthawi zina, mawonekedwe a kufooka kwa minofu ndi kupweteka.
Pa khungu
Ndi kukhazikitsa mankhwala mu minofu wosanjikiza kapena mu ulnar mtsempha, redness, phlebitis (kokha ndi kulowetsedwa kwa iv), kupweteka ndi kutupa m'malo omwe jekeseni anaikidwapo amatha kuchitika. Ndi chidwi chochulukirapo ku Actovegin, urticaria imawoneka.
Kuchokera ku chitetezo chamthupi
Mukatenga metabolic othandizira, kuyankha kwa chitetezo cha m'thupi ndi kuchuluka kwa leukocytes m'thupi kumatha kuchepetsedwa ngati muli ndi matenda opatsirana.
Matupi omaliza
Odwala omwe ali ndi minofu hypersensitivity, dermatitis ndi fever fever amatha. Nthawi zina, angioedema ndi anaphylactic angachitike.
Malangizo apadera
Mukabayidwa intramuscularly, muyenera kubaya pang'onopang'ono yankho mu gawo lakuya la minofu. Kuchuluka kwa mankhwalawa sikuyenera kupitirira 5 ml. Odwala omwe akuwonetsedwera kuti zimachitika kuti anaphylactic zimachitika, ndikofunikira kuyesa kuyesedwa koyambitsa 2 ml / m kuti mupeze kulolera kwa mankhwalawa.
Njira yothetsera vutoli imakhala yotuwa. Mphamvu ya mtundu wautoto wautoto imatha kusiyanasiyana kutengera ndi batani lomwe latulutsidwa komanso kuchuluka kwa zida zake. Izi sizimakhudza maselo amthupi ndipo sizimachepetsa kulolera kwa mankhwalawo. Chifukwa chake, pogula, palibe chifukwa chofunikira kuyang'ana mtundu wa yankho, koma simungagwiritse ntchito madzi omwe ali ndi tinthu tokhazikika.
Malo omwe atsegulidwa sakusungidwa.
Kuyenderana ndi mowa
Pa mankhwala ndi Actovegin ndizoletsedwa kumwa mowa. Ethanol amatha kuchepetsa zotsatira za metabolic ndi neuroprotective chifukwa cha kuletsa kwamkati mwa dongosolo lamanjenje.
Zokhudza mphamvu pakuwongolera njira
Mankhwalawa sasokoneza ntchito ya minyewa. Poyerekeza ndi momwe magwiridwe antchito amkati amanjenje amkati am'mimba, wodwala panthawi ya chithandizo ndi Actovegin saletsa kuyendetsa galimoto, kuchita zinthu zofunikira kwambiri komanso kuwongolera, ndikuwongolera zida zovuta.
Mukamalandira mankhwala ndi Actovegin, galimoto siiletsedwa.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Mankhwalawa saloledwa kuti azigwiritsidwa ntchito ndi amayi oyembekezera. Zinthu zomwe sizigwira ntchito sizilowa mu chotchinga cha hematoplacental, ndichifukwa chake sizikuwopseza kukula kwa embryonic kukula kwa mwana wosabadwayo. Mankhwala atha kuphatikizidwa pophatikiza mankhwalawa preeclampsia kapena kuthekera kwakukulu kokusochera.
The hemoderivative wonyongedwa samatulutsidwa kudzera m'matumbo a mabere, chifukwa chake, pakumwa mankhwala, kuyamwitsa kumatha kuchitika.
Mlingo Actovegin ana 200
Makanda obadwa kumene ndi makanda amaletsedwa kupereka mapiritsi a Actovegin chifukwa chakuchuluka kwa chiwopsezo cha asphyxiation. Jekeseni amalola kuti mulowetse mankhwalawo m'thupi la ana ndikuwonjezera mphamvu ya zinthu zomwe zimagwira. Mlingo umakhazikitsidwa ndi adotolo potengera kulemera kwa thupi kwa mwana. Ndikulimbikitsidwa kuti ana akhanda ndi akhanda azitha kupatsidwa mankhwala a Actovegin kamodzi patsiku / / kapena mu / m mlingo wa 0,4-0,5 ml pa 1 kg yolemera.
Kwa ana a zaka 1 mpaka 3, muyezo umodzi wa mankhwalawa utha kuwonjezeka mpaka 0,6 ml / kg yolemetsa thupi, pomwe mwana kuyambira zaka 4 mpaka 6, kuyamwa kwamankhwala osokoneza bongo kapena 0,25-0.4 ml / kg intramuscularly kapena kudzera m'mitsempha amaloledwa. patsiku. Mukamamwa mankhwala mkati, muyenera kupatsa ana mapiritsi a ¼. Zotsatira za kupatuka kwa mawonekedwe a mlingo, mphamvu ya mankhwalawo imachepa.
Gwiritsani ntchito mu ukalamba
Actovegin sifunikira kusintha muyezo wa mankhwalawa akaperekedwa kwa anthu azaka zopitilira 60.
Actovegin sifunikira kusintha muyezo wa mankhwalawa akaperekedwa kwa anthu azaka zopitilira 60.
Bongo
Panthawi yoyeserera kafukufuku woyeserera, zidapezeka kuti Actovegin, ikachulukitsa mlingo womwe umalimbikitsidwa nthawi 30-30, ilibe vuto lililonse mthupi ndi ziwalo zathupi. Nthawi yotsatsa pambuyo pazochita zamankhwala, palibe zochitika za bongo zomwe zalembedwa.
Kuchita ndi mankhwala ena
Mothandizidwa ndi mtsempha wa Mildronate ndi Actovegin, ndikofunikira kuyang'ana pakadutsamo pakati pa jakisoni wa maola angapo, chifukwa sikunenedwe ngati mankhwalawa amalumikizana.
Wothandizila kagayidwe kamayenda bwino ndi Curantil for gestosis (capillary vascular vuto) mwa amayi apakati omwe ali ndi chiopsezo chobadwa nthawi isanakwane.
Kuphatikiza komwe kumafunikira kusamala
Pogwiritsa ntchito mofananamo Actovegin ndi ACE inhibitors (Captopril, Lisinopril), tikulimbikitsidwa kuwunika momwe wodwalayo alili. An blockoter ya eniotensin-yotembenuza enzyme imayikidwa limodzi ndi metabolic wothandizira kuti magazi azithamanga mu ischemic myocardium.
Chenjezo liyenera kuchitika pakukhazikitsidwa kwa Actovegin ndi potaziyamu wothandiza kuponderezana.
Analogi
M'malo mankhwalawa pokhapokha achire zotsatira zake zingakhale mankhwala omwe ali ndi mankhwala omwewo:
- Vero-Trimetazidine;
- Cortexin;
- Cerebrolysin;
- Solcoseryl.
Mankhwalawa ndi otsika mtengo pamtengo wamtengo.
Malo opumulira Actovegin 200 kuchokera ku mankhwala
Mankhwalawo sagulitsidwa popanda kulandira mankhwala.
Kodi ndingagule popanda kulandira mankhwala?
Mankhwalawa amangoikidwa pazifukwa zachuma mwachindunji, chifukwa sizingatheke kudziwa zotsatira za Actovegin pa munthu wathanzi.
Mtengo
Mtengo wamankhwala ku Russia umasiyana ndi ma 627 mpaka 1525 rubles. Ku Ukraine, mankhwalawa amalipira pafupifupi 365 UAH.
Zosungidwa zamankhwala
Ndikofunikira kusunga mankhwalawo pa kutentha osaposa + 25 ° C.
Tsiku lotha ntchito
36 miyezi.
Wopanga Actovegin 200
Takeda Austria GmbH, Austria.
Makanda obadwa kumene ndi makanda amaletsedwa kupereka mapiritsi a Actovegin chifukwa chakuchuluka kwa chiwopsezo cha asphyxiation.
Ndemanga za madotolo ndi odwala pa Actovegin 200
Mikhail Birin, Neurologist, Vladivostok
Mankhwalawa sanatchulidwe ngati monotherapy, chifukwa chake zimakhala zovuta kulankhula za ogwira mtima. Chomwe chimagwiritsidwa ntchito ndi hemoderivative, chifukwa chake ndikofunikira kuyang'ana momwe wodwalayo aliri: sizodziwika momwe mankhwalawa amayeretsedwera panthawi yopanga, zomwe zingachitike chifukwa chogwiritsa ntchito. Odwala amalola mankhwalawa bwino, koma ndimakonda kudalira zopangidwa. Nthawi zina, mutu umayamba.
Alexandra Malinovka, wazaka 34, Irkutsk
Abambo anga anaulula thrombophlebitis m'miyendo. Gangrene anayamba, ndipo mwendo unadulidwa. Zinthu zinali zovuta ndi matenda a shuga; Adafunsidwa kuti akathandizike kuchipatala, komwe Actovegin adathandizidwa kudzera m'mitsetse. Zinthu zinayamba kuyenda bwino.Atatulutsa, abambo adatenga mapiritsi a Actovegin ndi jakisoni a 5 ml mwamphamvu malinga ndi malangizo ogwiritsa ntchito. Chilondacho pang'onopang'ono chidachira kwa mwezi umodzi. Ngakhale mtengo wokwera, ndikuganiza kuti mankhwalawa ndi othandiza.
