Astrozone ndi othandizira pakamwa. Ntchito kuchiza matenda a shuga a 2. Mukamagwiritsa ntchito mapiritsi, shuga m'magazi amabwerera mwakale mwachidule.
Dzinalo Losayenerana
INN: Pioglitazone.
Astrozone ndi othandizira pakamwa. Dzinalo losayenerera padziko lonse lapansi ndi Pioglitazone.
ATX
Code ya ATX: A10BG03.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwala amapezeka monga mapiritsi. Chofunikira chachikulu ndi pioglitazone mu Mlingo wa 30 mg. Zowonjezera zomwe zimapanga: lactose, magnesium stearate, hyprolose, croscarmellose sodium.
Mapiritsi amayikidwa mu zotumphukira m'matumba 10 zidutswa.
Mu phukusi 1 la makatoni mukhonza kukhala atatu kapena 6 mwa phukusi ili. Komanso, mankhwalawa amatha kupezeka muzitini za polymer (mapiritsi 30 aliyense) ndi mabotolo omwewo (zidutswa 30).
Zotsatira za pharmacological
Clinical microbiology imagawa mankhwalawa ngati mankhwala a thiazolidinedione. Mankhwalawa ndi wosankha wokonda eni ake a ma gamma zolandilira payekha.
Mu matenda a shuga a mtundu wachiwiri, mankhwalawa amachepetsa kukanira kwa insulin.
Amatha kupezeka m'chiwindi, minofu ndi adipose minofu. Chifukwa cha kuthandizira kwa ma receptor, kusintha kwa majini komwe kumapangitsa chidwi cha insulin kumasinthidwa mwachangu. Amathandizanso kutulutsa shuga m'magazi.
Ma metabolic a metabolid a metabolid amabwereranso kwachibadwa.
Mlingo wa kukana kwa zotumphukira zimakhala kuchepa, zomwe zimapangitsa kuti shuga ayambe kudalira insulin. Poterepa, mulingo wa hemoglobin mu seramu yamagazi umakhala wofanana.
Mu matenda a shuga a mtundu wachiwiri, insulin kukana maselo a chiwindi amachepetsa kwambiri. Izi zimapangitsa kuchepa kwa kuchuluka kwa shuga m'magazi, kuchuluka kwa insulini m'madzi am'magazi kumatsikanso.
Pharmacokinetics
Mutatha kumwa mapiritsi pamimba yopanda kanthu, kuchuluka kwa pioglitazone m'madzi a m'magazi kumachitika pakatha theka la ola. Ngati mumamwa mapiritsi mutatha kudya, ndiye kuti mavutowo amakwaniritsidwa maora angapo. Bioavailability komanso womanga kumapuloteni amwazi ndiwambiri.
Kagayidwe ka pioglitazone kamapezeka m'chiwindi. Hafu ya moyo ndi pafupifupi maola 7. Zinthu zogwira ntchito zimachotsedwa m'thupi momwe zimayambira metabolites pamodzi ndi mkodzo, bile ndi ndowe.
Zogwira ntchito za Astrozone zimapukusidwa mu mawonekedwe a metabolites ofunikira ndi mkodzo.
Zizindikiro zogwiritsidwa ntchito
Chizindikiro chotsimikizika chogwiritsira ntchito Astrozone ndi chithandizo cha matenda amtundu wa 2. Amagwiritsidwa ntchito ngati monotherapy kapena kuphatikiza ndi zotumphukira za sulfonylurea, metformin kapena insulin ngati chakudya, zochita zolimbitsa thupi ndi monotherapy sizimapereka zotsatira zomwe zikuyembekezeka.
Contraindication
Milandu yonse yokhudza kugwiritsa ntchito mankhwalawa ndi:
- Hypersensitivity ku zigawo zikuluzikulu;
- mtundu 1 matenda a shuga;
- matenda ashuga ketoacidosis;
- kuphwanya chiwindi ndi impso;
- nthawi ya pakati ndi mkaka wa m`mawere;
- ana ochepera zaka 18;
Ndi chisamaliro
Chenjezo limafunikira popereka mankhwala kwa anthu omwe ali ndi mbiri yakale ya:
- kutupa
- kuchepa magazi
- kusokonezeka kwa minofu ya mtima.
Kodi mutenge bwanji Astrozone?
Mapiritsi akulimbikitsidwa kuti atenge popanda kusakanikirana ndi chakudya, 1 nthawi patsiku. Ndikofunika kuchita izi m'mawa, nthawi yomweyo.
Mlingo watsiku ndi tsiku ndi 15-30 mg patsiku.
Pazipita mlingo tsiku lililonse sayenera kupitirira 45 mg.
Ndi matenda ashuga
Ngati mumagwiritsa ntchito mankhwalawa limodzi ndi ena othandizira kapena ma metformin, chithandizo chikuyenera kuyamba ndi mlingo wochepa, i.e. osapitilira 30 mg pa tsiku.
Kuphatikiza pamodzi ndi insulin kumaphatikizapo kugwiritsa ntchito limodzi mlingo wa Astrozone mu 15-30 mg patsiku, ndipo mlingo wa insulin umakhalabe womwewo kapena umachepa pang'onopang'ono, makamaka pankhani ya hypoglycemia.
Zotsatira zoyipa za Astrozone
Zimayambitsa zingapo zoyipa, zomwe zimatha kuchitika popanda kutsata molakwika kapena kuphwanya lamulo.
Astrozone imayambitsa kulephera kwa mtima.
Pafupifupi nthawi zonse, odwala amakhala ndi zotupa zakumapeto. Kuwonongeka kwamawonekedwe kumatha kuphatikizidwanso ndi kusintha kwa kuchuluka kwa shuga m'magazi, makamaka kumayambiriro kwa chithandizo. Nthawi zina, kukula kwa mtima kulephera ndikotheka.
Matumbo
Nthawi zambiri zimachitika mwachisawawa.
Hematopoietic ziwalo
Anemia imawonetsedwa, kuchepa kwambiri kwa hemoglobin ndi hematocrit m'magazi.
Kuchokera kumbali ya kagayidwe
Nthawi zambiri, mukamamwa mankhwalawa, kuwonjezeka kwa kulemera kwa thupi ndikukula kwa hypoglycemia kumayang'aniridwa, komwe kumachitika chifukwa chophwanya kagayidwe kazigawo m'thupi.
Zokhudza mphamvu pakuwongolera njira
Chifukwa Chifukwa chogwiritsa ntchito mankhwalawa, kukula kwa hypoglycemia ndikotheka, limodzi ndi chizungulire komanso kukwiya, muyenera kukana kuyendetsa galimoto ndikuwongolera njira zina zovuta kuzimitsa. Vutoli likhoza kuthana ndi kuthamanga kwa kuchitapo kanthu komanso kuzama.
Muyenera kukana kuyendetsa galimoto panthawi yamankhwala ndi Astrozone.
Malangizo apadera
Mosamala, mankhwala amalembedwa kwa odwala omwe ali pachiwopsezo cha edema, komanso opaleshoni (asanachitike opaleshoni). Matendawa amatha kuyamba (kutsika kwapang'onopang'ono mu hemoglobin nthawi zambiri kumalumikizidwa ndi kuchuluka kwa magazi omwe amayenderera m'mitsempha.
Kuwunika kuchuluka kwa hypoglycemia ndikofunikira pakugwiritsa ntchito mankhwala limodzi ndi ketoconazole.
Kupatsa ana
Osalimbikitsa osagwiritsidwa ntchito mankhwalawa pochiza ana.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Kutenga mapiritsi kumapangidwa pakati pa nthawi ya gestation komanso poyamwitsa. Ngakhale zatsimikiziridwa kuti zinthu zomwe sizigwira ntchito zilibe mphamvu pachonde, ndibwino kusiya njira yotereyi pakukonzekera kutenga pakati.
Kutenga mapiritsi a Astrozone kumapangidwira pakamwa.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Simungathe kugwiritsa ntchito mankhwalawa ndi kuchuluka kwa chiwindi chilichonse cha pathologies. Ngati mayesero a chiwindi kumayambiriro kwa chithandizo anali abwinobwino, ndiye kuti ndi bwino kupereka mankhwala ochepetsa mphamvu. Koma muyenera kuyang'anira mawonetseredwewo ndipo pakakhala kuwonongeka pang'ono, kuletsa mankhwalawo.
Mankhwala osokoneza bongo a Astrozone
Palibe milandu ya bongo ya Astrozone yomwe idadziwika kale. Ngati mwangozi mwalandira mlingo waukulu wa mankhwalawa, zovuta zoyipa zomwe zimawonetsedwa ndi vuto la dyspeptic ndikukula kwa hypoglycemia kumatha kukulitsidwa.
Panthawi ya chizindikiro cha bongo, ndikofunikira kuchita mankhwala osokoneza bongo mpaka zotsekemera zonse zithe.
Ngati hypoglycemia iyamba kukulira, detoxification mankhwala ndi hemodialysis angafunike.
Ngati hypoglycemia imayamba ndi mankhwala osokoneza bongo a Astrozone, hemodialysis ingafunike.
Kuchita ndi mankhwala ena
Mukamagwiritsa ntchito limodzi ndi kulera kwamlomo, kuchepa kwamphamvu kwa metabolites yogwira ntchito kumawonedwa. Chifukwa chake, kupambana kwa kugwiritsa ntchito njira zakulera kumachepetsedwa.
Njira ya pioglitazone metabolism mu chiwindi imakhala yotseka kwathunthu ngati imagwiritsidwa ntchito ndi ketoconazole.
Kuyenderana ndi mowa
Simungathe kuchita mankhwala ndi mankhwala ndikumwa mowa. Izi zitha kubweretsa zowonjezera pamagetsi. Chiwopsezo chokhala ndi dyspeptic phenomena chikuwonjezeka. Zizindikiro za kuledzera zikuchulukirachulukira.
Analogi
Pali mitundu ingapo ya Astrozone analogues yomwe ili yofanana ndi izi malinga ndi zomwe zimagwira ntchito:
- Diab Norm;
- Diaglitazone;
- Amalvia
- Piroglar;
- Pyoglitis;
- Peouno
Kupita kwina mankhwala
Mankhwala amaperekedwa kuchokera ku mfundo zamankhwala pokhapokha ngati pali chithandizo chapadera kuchokera kwa dokotala.
Kodi ndingagule popanda kulandira mankhwala?
Ayi.
Mtengo wa Astrozone
Mtengo umachokera ku ma ruble 300-400. phukusi, mitengo imakhudzidwa ndi dera lomwe likugulitsidwa komanso malire a pharmacy.
Zosungidwa zamankhwala
Sungani pamalo owuma komanso amdima, kutali ndi ana ang'onoang'ono ndi ziweto, kutentha kwa + 15-25 ° C.
Tsiku lotha ntchito
Osapitilira zaka 2 kuchokera tsiku lopangira lomwe lasonyezedwa pa phukusi. Osagwiritsa ntchito kumapeto kwake.
Analogue ya Astrozone - mankhwala a piuno sangathe kugwiritsidwa ntchito kumapeto kwa tsiku lotha ntchito.
Wopanga
Kampani yopanga: OJSC Pharmstandard-Leksredstva, Russia
Ndondomeko ya Astrozone
Oleg, wazaka 42, Penza
Kwa nthawi yayitali ndakhala ndikuvutika ndi matenda ashuga a 2. Mankhwala ambiri adayikidwa, koma mphamvu zake sizinatenge nthawi yomwe timafuna. Ndipo sizinali zotheka kwa ine kupanga jakisoni nthawi zonse. Ndipo pomwepo dotolo adandiwuza kuti ndimwe mapiritsi a Astrozone. Ndimamva kuthekera kwa iwo mwachangu mokwanira. Zinthu ziyamba kuyenda bwino. Kuchuluka kwa shuga m'magazi kungobwera kwawokha pakatha milungu ingapo. Poterepa, piritsi limodzi ndi lokwanira tsiku lonse. Kukhutira ndi zotsatira za chithandizo.
Andrey, wazaka 50, Saratov
Dotolo adayikira mapiritsi a Astrozone pa 15 mg patsiku chifukwa chakuti poyambira chithandizo panali mayeso oyipa a chiwindi. Koma kumwa koteroko sikunathandize. Dokotala adalimbikitsa kuwonjezera kuchuluka kwa 30 mg patsiku, yomwe idapereka zotsatira zomveka. Malinga ndi kusanthula, chizindikiro cha glucose chatsika. Zotsatira zake zidatenga nthawi yayitali mpaka mankhwala atachotsedwa. Mayeso ake atayamba kuipiraipira, adotolo adakhazikitsa mlingo wa 15 mg wa patsiku. Shuga wakhala ali pamlingo womwewo kwa pafupifupi chaka chimodzi, chifukwa chake sindinganene chilichonse chokhudza mankhwala.
Peter, wazaka 47, Rostov-on-Don
Mankhwalawo sanakwane. Sindinamve chilichonse kuchokera ku gawo loyamba la 15 mg. Malinga ndi zotsatira za kafukufukuyu, palibenso zosintha zapadera. Mankhwala atangowonjezereka mpaka 30 mg, zinthu zambiri zimangokulirakulira. Hypoglycemia yayikulu idayamba, zomwe zizindikiro zake zinkangondiperewera. Ndinayenera kusintha mankhwalawo.
