Matenda a khunyu amatanthauza matenda amitsempha yamagulu osakhazikika. Imayendera limodzi ndi kukomoka, komwe wodwala amayenera kupatsidwa mankhwala othandizira chidwi. Mankhwalawa akuphatikizapo Convalis, kusiya kukakamira pang'ono. Mu kapangidwe kake ka mankhwala pali chinthu chapadera, chifukwa chomwe mankhwalawa amapereka ndi analgesic kwenikweni. Ali ndi contraindication, pamaso pake momwe kugwiritsa ntchito mankhwalawa sikuvomerezeka. Kugwiritsa ntchito kwazinthuzo mankhwala monga mankhwala kumachitika mogwirizana ndi malangizo.
Dzinalo
Mankhwalawa adapatsidwa dzina la International Nonpparetary Name (INN) - Gabapentin, dzina lachi Latin ndi Convalis.
Convalis ndi mankhwala omwe amathandizanso kukakamira pang'ono.
ATX
Nambala ya ATX ndi N03AX12, nambala yolembetsa ndi LS-001576 ya 01.12.2017.
Kutulutsa mafomu ndi kapangidwe kake
Kutulutsidwa kwa mankhwalawa ndi makapisozi achikasu achikasu. Poda yoyera ya kristalo yoyera ilipo mkati mwa chidebe cha gelatin. Wopangayo amapereka kuti pakhale zida zothandizira komanso zogwira ntchito. Zofunikira kwambiri zimaphatikizapo 300 mg gabapentin. Zina zikuphatikiza:
- lactose monohydrate;
- pregelatinized chomera wowuma (chimanga);
- mchere wa magnesium wa stearic acid;
- talcum ufa.
Chigoba cha gelatin chimakhala ndi zinthu izi:
- gelatin;
- utoto wachikasu;
- titanium dioxide.
Makapisozi amayikidwa mu chithuza mapaketi 10 ma PC. Mu phukusi - zosapitilira 5. Bokosilo lili ndi zidziwitso zonse zofunika, kuphatikizapo adilesi ya wopanga, nambala ya batch ndi tsiku lotha ntchito. Malangizo ogwiritsira ntchito amaphatikizidwa phukusi lililonse.
Zotsatira za pharmacological
Choyambira choyambirira chimafanana ndi gaba neurotransmitter. Mosiyana ndi barbiturates, valproic acid, ma inhibitors osankha a gaba-transaminase, gaba-agonists ndi benzodiazepine, anticonvulsant sichikhudza kagayidwe ndi kugunda kwa GABA. Kuphatikiza pa antiepileptic zotsatira, mankhwalawa amatha kuyimitsa kupweteka kwa neuropathic mu pathologies ena.
Convalis imakhala ndi chinthu chapadera, chifukwa chomwe mankhwalawa amapereka ndi mphamvu ya analgesic.
Calcium ions imagwira ntchito yofunika kwambiri pakuwonjezera kupweteka kwamitsempha yam'mimba. Mothandizidwa ndi chinthu chachikulu, chimfine cha ion chimaponderezedwa, kufa kozungulira kwa glutamate kumachepa, kuphatikizika kwa gaba kumawonjezeka, kumasulidwa kwaulere kwa monoamine neurotransmitters kumafooka. Kutengera ndi malingaliro onse azachipatala ndi mtundu wina wa mankhwala, palibe ligamu yothandizira ndi GABA receptors. Kuyanjana ndi njira za sodium kulibe.
Pharmacokinetics
Pazipita ndende yogwira ntchito m'madzi am'magazi pambuyo pa kumwa koyamba kwa mankhwalawa pambuyo pa maola 2 ndi 2,5. The bioavailability pafupifupi, osati amadalira mlingo ndipo 60%. Mukapitilira muyeso woyenera, bioavailability amachepetsa. Mankhwalawa amaloledwa kumwa, ngakhale zakudya. Chakudya sichimakhudza kuchuluka kwa mayamwa.
Gilapentin amachotsa impso. Ndi hemodialysis, imatsala pang'ono kuthetsedwa. Hafu ya moyo ndi pafupifupi maola 6-7. Thupi silimangiriza mapuloteni a plasma, samapukusidwa.
Kodi chimathandiza ndi chiyani?
Mankhwala osokoneza bongo atha kuphatikizidwa ndi mankhwala ngati wodwala wapezeka kuti ali ndi khunyu. Kuphatikiza apo, mankhwalawa amaperekedwa kwa matenda omwe amayenda ndi ululu waukulu:
- matenda a musculoskeletal system (hernia ya msana, rickets, radiculitis, osteochondrosis);
- matenda a chapamwamba komanso am'munsi kupuma thirakiti (otitis media, zovuta pambuyo chimfine);
- kupweteka kwa mitsempha ya mitsempha yosiyanasiyana, kuphatikiza mutu.
Contraindication
Mankhwala a anticonvulsant ali ndi zotsutsana zingapo komanso zotsutsana kwathunthu. Pamaso pa kugwiritsa ntchito mankhwalawa mankhwala othandizira achire komanso prophylactic sizovomerezeka. Izi zikuphatikiza ndi izi:
- kapamba pakachulukidwe;
- kobadwa nako ndi kukhala lactose tsankho;
- Hypersensitivity kapena kusalolera payekhapayekha.
Mankhwalawa ali ndi zoletsa zaka. Ana ochepera zaka 12 saloledwa kugwiritsa ntchito makapisozi a anticonvulsant.
Ndi chisamaliro
Contraindication zothandizira zimaphatikizapo kulephera kwaimpso, komwe kumafunika kugwiritsa ntchito mosamala.
Kodi mutenge Convalis?
Fomu ya mankhwalawa imatengedwa pakamwa: makapisozi ayenera kumwedwa nthawi yakudya kapena itatha, nthawi yomweyo, osatsegula chidebe cha gelatin. Sambani ndi madzi ofunda (osachepera 100 ml).
Mankhwalawa angagwiritsidwe ntchito ngati gawo la monotherapy komanso monga othandizira.
Mlingo komanso njira za kasamalidwe zimasankhidwa payekhapayekha.
Zotsatira za tsiku ndi tsiku zotsatirazi zimayikidwa mu fakitale malangizo:
- tsiku loyamba - 300 mg (kamodzi);
- tsiku lachiwiri - 600 mg (kawiri m'maola 24);
- tsiku lachitatu - 900 mg (katatu mu maola 24).
Ana osaposa zaka 12 saloledwa kutenga Convalis.
Ndi chilolezo cha dokotala, kuchuluka kwa tsiku ndi tsiku kumatha kuwonjezeka mpaka 1200 mg. The pakati pakati Mlingo sayenera upambana 8 maola. Ndi kupweteka kwambiri kwa neuropathic mwa akulu, amaloledwa kugwiritsa ntchito 1 kapisozi katatu patsiku. Ndi zoletsedwa konse kumwa oposa 300 mg a gabapentin kamodzi.
Kumwa mankhwala a shuga
Kutengera mtundu wa shuga, wodwala angafunike kusintha njira. Kugwiritsa ntchito mankhwala pamodzi ndi mankhwala a hypoglycemic kumafuna kuchepetsedwa kwa mlingo wotsiriza. Mlingo wothira tsiku lililonse pamilandu iyi sayenera kupitirira 900 mg.
Kutenga nthawi yayitali bwanji?
Nthawi yogwiritsira ntchito ndi masiku 5-7. Pokhapokha ngati pali zabwino, zitha kupitilizidwa ndi chilolezo cha adokotala.
Zotsatira zoyipa
Malamulo osankhidwa mosayenera a dosing amawonjezera chiopsezo cha mavuto kuchokera ku ziwalo zamkati ndi kwamkati wamanjenje.
Matumbo
Ndi mankhwala osayenera a ululu wa neuropathic odwala omwe ali ndi dongosolo la m'mimba, zotsatirazi zimawonedwa:
- kutsegula m'mimba
- kamwa yowuma
- kudzimbidwa
- kupweteka kwa epigastric;
- kupanga gasi kwambiri;
- akukumbutsa.
Zotsatira zoyipa zamisala:
- gingivitis;
- nseru
- matenda a anorexia;
- stomatitis
- kusokonezeka kwa chopondapo;
- dyspepsia.
Kukula kudya kungawonekere kukhala mavuto.
Hematopoietic ziwalo
Kuchokera kumbali ya ziwalo za hemopoietic, kuvulala (monga kuvulala), leukopenia imawonedwa.
Pakati mantha dongosolo
Mankhwalawa neuropathic ululu ku chapakati mantha dongosolo, zotsatirazi mavuto.
- Chizungulire
- kugona
- amnesia osakhalitsa;
- kuwonongeka kwamawonekedwe;
- kugwedezeka
- chisokonezo.
- ataxia.
Ngati mwakomoka pang'ono:
- kufooka kwa tendon Reflex;
- zosokoneza pamalingaliro am'mbuyo;
- paresthesia;
- Kuda nkhawa
- kusowa tulo
- nystagmus;
- kusowa kwa mgwirizano;
- amnesia.
Kuwunika ndi kuwunika kumawoneka pang'ono.
Convalis imatha kuyambitsa nkhawa, nkhawa komanso kusokoneza zina pamalingaliro.
Kuchokera kwamikodzo
Matenda amchiberekero omwe amachitika pakukhazikitsidwa kwa mankhwalawa amawonedwa ngati mavuto.
Kuchokera ku kupuma
Mbali iyi ya mankhwalawa matenda a kupuma ziwalo:
- pharyngitis;
- kupuma movutikira.
Zotsatira zoyipa zina za kugwidwa:
- chibayo
- rhinitis;
- chifuwa chowuma.
Ndi mankhwala osankhidwa bwino mosiyanasiyana, kupumira mofulumira kumatha kuonedwa.
Kuchokera ku minculoskeletal system
Myalgia, kusokonekera kwa minofu ya mafupa, kupweteka kumbuyo ndi mafupa, arthralgia amatchedwa zotsatira zoyipa.
Kuchokera ku kubereka
Mwa amuna, ndi mankhwala olakwika, kusabala kumayamba.
Matupi omaliza
Thupi lawo siligwirizana mu 56% ya odwala. Pochiza ululu ndi kukomoka, zotsatirazi zingaoneke:
- zotupa
- Khungu;
- ziphuphu
Nthawi zambiri pochiza zowawa ndi kukomoka ndi Convalis, odwala amakhala ndi kuyabwa pakhungu.
Zingwe pakhungu sizingakwiyitsidwe, mwinanso zikwangwani zimawoneka.
Malangizo apadera
Kuwonetsa mkodzo pafupipafupi pakugwiritsa ntchito mankhwala anticonvulsant kungakhale kwabwino. Pankhaniyi, muyenera kuyipatsanso. Odwala omwe adapezeka ndi matenda ashuga ayenera kumwa mankhwala ochepa a hypoglycemic.
Ndi kuchulukana kwa kapamba, ndizoletsedwa kumwa mankhwala. Sitikulimbikitsidwa kusiya mwadzidzidzi mankhwalawo kapena kuisintha ndi analog. Kuchepetsa kwa mankhwalawa kumayenera kumachitika pang'onopang'ono, apo ayi, kusiya zina kumayamba (kusanza, chizungulire, kukomoka).
Pa mankhwalawa neuropathic ululu ndi khunyu, ndikofunikira kuwunika momwe wodwalayo alili. Kuopsa kwa malingaliro odzipha kukuchulukirachulukira. Pakulephera kwa aimpso, kusintha kwa muyezo wofunikira kukufunika. M'masiku omwe dialysis singachitike, mankhwalawa sagwiritsidwa ntchito.
Zokhudza mphamvu pakuwongolera njira
Pogwiritsa ntchito mankhwalawa kwa nthawi yayitali, wodwalayo amakhala ndi tulo, motero, ndi bwino kusiya kuyendetsa galimoto ndi njira zina.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Mankhwala pa nthawi ya pakati amagwiritsidwa ntchito pokhapokha ngati phindu lomwe lingakhalepo kwa mayi limaposa chiwopsezo cha mwana wosabadwayo.
Gawo lalikulu limadutsa mkaka wa m'mawere, chifukwa chake silikulimbikitsidwa kumwa mankhwalawa mukamayamwa.
Kulembera Convalis kwa ana
Kwa ana ochepera zaka 12, mankhwalawa saikidwa mankhwala. Kwa achinyamata, dongosolo la mankhwalawa limasankhidwa payekhapayekha.
Gwiritsani ntchito mu ukalamba
Odwala okalamba ayenera kumwa mankhwalawa moyang'aniridwa ndi dokotala. Mlingo ungafunike.
Odwala okalamba ayenera kumwa mankhwalawa moyang'aniridwa ndi dokotala.
Bongo
Ngati chizolowezi cha tsiku ndi tsiku chikuchulukitsidwa kangapo, wodwalayo amakhala ndi zizindikiro za bongo. Izi zikuphatikiza:
- diplopia;
- Chizungulire
- kugona
- dysarthria;
- kusokonezeka kwa chopondapo.
Panalibe kufa ndi mankhwala osokoneza bongo. Pankhaniyi, kukadandaula ku chipatala ndikofunikira, dokotala yemwe akupezekapo amasankha chithandizo chamankhwala. Palibe mankhwala.
Kuchita ndi mankhwala ena
Ndi munthawi yomweyo makonzedwe a cimetidine ndi anticonvulsant, nthawi yochuluka ya chomaliza imachulukirachulukira. Sichikugwirizana ndi phenytoin, carbamazepine, phenobarbital ndi valproic acid. Njira zakulera za pakamwa, zomwe zimakhala ndi norethisterone ndi ethinyl estradiol, sizigwirizana ndi mankhwalawa.
Maantacid, momwe mchere wa magnesium kapena aluminiyamu ulipo, amatha kuchepetsa kukonzekera kwa mankhwalawa. The pakati pakati Mlingo ndi 2 hours. Pimetidine amachepetsa kuchotsa kwa chinthu chachikulu.
Kuyenderana ndi mowa
M'pofunika kukana zakumwa zoledzeretsa panthawi yamankhwala. Ethanol imatha kupangitsa kukulitsa zotsatira zoyipa.
Convalis sangatengedwe ndi mowa, Mowa umatha kuyambitsa zovuta.
Zolemba za Convalis
Mankhwala okhala ndi anticonvulsant amankhwala ali ndi mitundu ingapo yodziyimira ndi mitundu. Zotsatira zakuchiritsa zamankhwala awa ndizofanana ndi zoyambirira.
- Algerica. Analogue yachilengedwe ya mankhwala oyamba amapezeka mu mawonekedwe a makapisozi. Pregabalin (mpaka 300 mg) amakhala ngati gawo lalikulu. Wopanga amapanga kukhalapo kwa ochulukirapo. Amagwiritsidwa ntchito pochiza ululu wa neuropathic ndi khunyu. Mtengo muma pharmacies ndi ma ruble 430.
- Topamax Mankhwala a anticonvulsant amagwiritsidwa ntchito popewa migraine komanso njira zochizira matenda akhunyu. Topiramate (15, 25 ndi 50 mg) ndi chinthu chogwira ntchito. Mtengo wa mankhwalawo ndi ma ruble 1100.
- Keppra. Amapezeka mu mapiritsi ndi kuyimitsidwa pakamwa. Chofunikira kwambiri ndi levetiracetam pa ndende ya 500 mg. Imakhala ndi anticonvulsant zotsatira ndipo imawerengedwa kuti ndi yoyambirira. Mtengo m'mafakitale amachokera ku ma ruble 770.
- Carbamazepine, wogwiritsa ntchito mankhwala oyamba, amapezeka piritsi. The zikuchokera muli yemweyo yogwira thunthu - 200 mg. Mtengo muma pharmacies umayambira ma ruble 50.
Chilichonse cholowa m'malo chimakhala ndi zotsutsana. Mwina chitukuko cha mavuto. Ena mwa mankhwalawa ochokera kwa wopanga akunja (Sweden, India, dziko la US ku Michigan) atha kufananizidwa ndi zoyambirira.
Kupita kwina mankhwala
Mankhwala anticonvulsant amafunikira kuti apatsidwe mankhwala ku pharmacies.
Kodi ndingagule popanda kulandira mankhwala?
Simungagule mankhwala popanda mankhwala a dokotala.
Mtengo
Mtengo wopaka ndi mankhwala umayamba kuchokera ku ma ruble 500.
Malo osungirako a Convalis
Optimum yosungirako kutentha - mpaka + 25 °. Malo osungirako - owuma, amdima, osafikirika kwa ana ndi nyama.
Tsiku lotha ntchito
Sungani miyezi yopitilira 36 kuchokera tsiku lopangira.
Ndemanga za madotolo ndi odwala pa Convalis
Krasavina Valentina, wamisala, Novorossiysk.
Ndikudziwa mankhwalawa kwa nthawi yayitali, ngakhale isanayambe kumasulidwa ku Russian Federation. Chida chake ndichothandiza, chimaletsa msanga kupweteka kwa chikhalidwe cha neuropathic. Pochita, ndimagwiritsa ntchito kwa zaka zingapo, odwala amakhutira ndi zotsatira zake, koma ena amadandaula za kukhazikitsidwa kwa zotsatira zosayenera.
Nthawi zambiri, thupi limakumana ndi zovuta m'magazi amkati amanjenje. Kuwala pakhungu kumathandizidwa ndi wothandizira aliyense wa antihistamine wakunja. Kugona kudzimiririka pakokha patatha masiku ochepa, thupi litazolowera.
Nina Goryunova, wazaka 64, Ekaterinburg.
Matenda a shuga ndi opezedwa zaka zoposa 15 zapitazo. Matendawa amapitilira pang'onopang'ono, thupi linasiya kupirira. Poona izi, ululu udawonekela molumikizana manja ndi miyendo, yomwe idakula usiku. Ndinayesa mafuta osiyanasiyana, ma gele, mafuta osiyanasiyana - sizinathandize. Pa phwando, adadandaula kwa dotolo, adamuwuza mankhwala omwe angamupweteketse ululu wammbuyo.
Ndinagula ndi mankhwala. Kugwiritsidwa ntchito molingana ndi malangizo, pang'onopang'ono kuwonjezera mlingo. Sindinatenge mapiritsi oposa 3 patsiku. Pambuyo pa masiku 5, adayamba kuchepetsa mlingo. Dokotala anachenjeza kuti simungathetse mankhwalawo mwachangu. Patsiku loyamba kugona kunawoneka, koma kudutsa kwaokha.
