Dimaril wa mankhwala: malangizo ogwiritsira ntchito

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Dimaril ndi mankhwala othandizira odwala matenda ashuga. Amalembera mankhwalawa odwala matenda a shuga.

Dzinalo Losayenerana

Glimeperide

Dimaril ndi mankhwala othandizira odwala matenda ashuga. Amalembera mankhwalawa odwala matenda a shuga.

Ath

A10BB12 - Glimepiride

Kutulutsa mafomu ndi kapangidwe kake

Yogwira pophika mankhwala ndi glimepiride. Piritsi limodzi lili ndi 2, 3 mg kapena 4 mg pa chinthu ichi. Zothandiza: lactose monohydrate, indigo carmine aluminium varnish, microcrystalline cellulose, sodium starch glycolate, magnesium stearate, povidone, polysorbate 80, iron oxide chikasu.

Zotsatira za pharmacological

Kufika pachilonda, glimepiride (yogwira mankhwala), kumakhala ndi zotsatirapo zina zama cell:

  • imalimbikitsa kupanga ndi kutulutsa kwa insulin ya ma cell a beta masamba a kapamba;
  • zimapangitsa kuti zotumphukira zimveke kwambiri ndi insulin;
  • imagoda postprandial insulin / C-peptide metabolism.

Chifukwa cha zomwe takambirana pamwambapa, kuchuluka kwa shuga kwa wodwalayo kumakhala kwacibadwa.

Pharmacokinetics

Mlingo wa shuga umachepa maola 2-3 mutatha kugula mankhwalawa, umatha kupitirira tsiku limodzi ndikuwukhazikika kwa masabata awiri. Odwala ena okhala ndi shuga wambiri, pafupifupi 6 g ya mankhwalawa amayenera kutengedwa kuti akwaniritse zochizira.

Mlingo wa shuga umachepera maola 2-3 mutatenga Dimaril, kumatha kuposa tsiku ndipo mumakhazikika kwa masabata awiri.

Zizindikiro zogwiritsidwa ntchito

Type 2 matenda a shuga, kukana insulini.

Contraindication

Contraindication kuti agwiritse ntchito akuphatikizapo: mtundu 1 wa matenda ashuga mellitus (wodwala-insulin), matenda ashuga ketoacidosis, precoma ndi chikomokere, magwiridwe antchito a impso ndi chiwindi. Mankhwala sayenera kutumizidwa kwa odwala omwe ali ndi hypersensitivity kuti glimepiride, othandizira zigawo za mankhwala, zotumphukira za sulfonylurea ndi mankhwala ena a sulfonamide.

Ndi chisamaliro

Mankhwala amathandizidwa mosamala odwala omwe akufuna kusamukira ku insulin. Vutoli limachitika povulala kwambiri, kupsa kwambiri komanso kuchitapo kanthu opaleshoni. Kuphatikiza apo, zoletsa kugwiritsa ntchito mankhwalawa ndi: uchidakwa, kusokonezeka kwa chakudya komanso mankhwala osokoneza bongo, matenda a kutentha thupi, kuchepa kwa adrenal, matenda a chithokomiro, kuchuluka kapena kuchepa kwa kupanga kwa mahomoni a chithokomiro.

Zizindikiro Dimaril - Type 2 shuga mellitus, insulin kukana.

Momwe mungatenge Dimaril

Mlingo wambiri ungasiyane kutengera gawo la matenda.

Ndi matenda ashuga

Asanayambe chithandizo, odwala amapereka magazi ndi mkodzo kuti awunikidwe. Chifukwa cha kafukufuku, madokotala amazindikira kuchuluka kwa shuga. Kutengera ndi zomwe zidawerengedwa, madokotala amakupangira kuchuluka kwake:

  1. Mlingo woyambirira ndi 1 mg ya glimepiride patsiku. Awa ndi mapiritsi ½ a 2 mg. Atavomereza, dokotala amayang'anira bwino zomwe wodwalayo akuchita. Ngati katswiri amvetsetsa kuti kumwa koteroko kumathandizira kuthana ndi matendawa, ndiye kuti amamuika ngati mankhwala ochiritsira.
  2. Mlingo wowonjezereka ndi 2, 3 kapena 4 mg ya mankhwala patsiku. Amasankhidwa ngati 2 mg sikokwanira. Kutalika kwa njira ya achire amakhazikitsidwa payekhapayekha.
  3. Mlingo wapamwamba ndi 4-6 mg ya mankhwala. Mlingo wa mankhwalawa umaperekedwa kwa odwala omwe ali ndi kuchuluka kwa glucose (ngati chikhazikitso cholimba cha chinthu chimawonedwa ngakhale pamimba yopanda kanthu).
Asanayambe chithandizo, odwala amapereka magazi ndi mkodzo kuti awunikidwe.
Chifukwa cha kafukufuku, madokotala amazindikira kuchuluka kwa shuga. Kutengera ndi zomwe zidapezeka, madokotala amakupatsani mankhwalawa.
Kuphatikiza mankhwala kuyenera kuchitika moyang'aniridwa ndi dokotala.

Kuphatikiza mankhwala kuyenera kuchitika moyang'aniridwa ndi dokotala. Kuphatikiza apo, ndikofunikira kuyang'anira moyo: chepetsa kuchuluka kwa masewera olimbitsa thupi, kupewa kugwiritsa ntchito zinthu za hypoglycemic (zomwe zimapangitsa kuchepa kwambiri kwa shuga) ndikutsatira zakudya.

Zotsatira zoyipa za Dimaril

Zotsatira zoyipa zimatha kuchitika.

Pa mbali ya gawo la masomphenyawo

Kumayambiriro kapena pakati pa chithandizo, wodwalayo amatha kuyambiranso kwakanthawi. Zotsatira zoyipa izi zimagwirizanitsidwa ndi kusintha kwakuthwa kwa plasma glucose.

Matumbo

Odwala ena amakumana ndi kudzimbidwa, chifukwa komwe amakhala ndi ululu m'zigawo za epigastric, amasintha tulo, nseru komanso kusanza. Zizindikiro nthawi zambiri zimatsagana ndi kulemera m'mimba. Nthawi zina, ntchito ya chiwindi michere imachuluka. Woopsa, matenda monga hepatitis, cholestasis ndi jaundice amakula. Pathologies imatha kubweretsa zovuta zina - kulephera kwa chiwindi.

Hematopoietic ziwalo

Pa mayeso a labotale, kusintha kwa kuchuluka kwa maplatelet, leukocytes, maselo ofiira am'magazi, granulocytes, agranulocytes amapezeka. Nthawi zina, kuchepa kowopsa m'magazi onse ndi kotheka, komanso hemolytic kapena anemia wa magazi.

Kumayambiriro kapena pakati pa chithandizo ndi Dimaril, wodwalayo amatha kusokoneza masanjidwe kwakanthawi.
Kuphwanya kwamanjenje kumawonetsedwa m'mutu ndi mutu wa asthenia - chikhalidwe chofooka komanso chopanda mphamvu.
Zosintha mu kupuma zimatheka ngati wodwalayo akayamba kudwala - kumva kuti alibe mpweya.
Odwala ena amakhala ndi kudzimbidwa, chifukwa komwe amavutika ndi ululu m'dera la epigastric, amasintha mu tulo.

Pakati mantha dongosolo

Kuphwanya kwamanjenje kumawonetsedwa m'mutu ndi mutu wa asthenia - chikhalidwe chofooka komanso chopanda mphamvu.

Kuchokera ku kupuma

Zosintha mu kupuma zimatheka ngati wodwalayo akayamba kudwala - kumva kuti alibe mpweya. Kuphatikiza apo, zotsatira zoyipa zimatha kuchitika chifukwa cha zovuta zoyipa zomwe zimagwidwa, nthawi zambiri zimayendera limodzi ndi kukwana.

Pa khungu

Ndi kusalolera kwa zigawo zikuluzikulu kapena chizolowezi cha thupi lawo siligwirizana, khungu limasinthasintha odwala. Kuchepetsa ndi zotupa zosiyanasiyana kumawonedwa, komwe kumayendetsedwa ndi kuwotcha komanso kuyabwa kwambiri. Momwe zimachitikira kawirikawiri matendawa ndi urticaria. Ili ndi gulu la matenda omwe amaphatikiza chizindikiro chodziwika - mawonekedwe a matuza ofiira pakhungu, ofanana ndi totupa ndi nettle burn.

Kuchokera pamtima

Nthawi zina, kuchuluka kwambiri kwa magazi kumatheka.

Kuchokera ku chitetezo chamthupi

Mwina chitukuko cha hypersensitivity zimachitika, amene akuwonetsedwa mu mawonekedwe a totupa, edema, thupi lawo siligwirizana ndi photosensitivity. Woopsa milandu, matupi awo sagwirizana ndi omwe amatuluka - Mtundu wa Quincke ndi kuwonongeka kwa anaphylactic.

Kulandila kwa Dimaril kumayambitsa kusokonezeka kwa chidwi, ndipo kuthamanga kwa ma psychomotor kumachepa.

Zokhudza mphamvu pakuwongolera njira

Kumayambiriro kwa chithandizo, kuchuluka kwa shuga m'magazi kumakhala kosakhazikika. Pakati pa zochizira, kuphatikiza shuga kumatha kuwonjezeredwa kapena kuchepetsedwa, komwe kumalumikizidwa ndi kusakhazikika kwa mankhwalawa kapena zolakwitsa zina zomwe wodwalayo amapanga. Izi zimabweretsa kuphwanya kwa ndende, komanso kuthamanga kwa ma psychomotor zimachepa.

Malangizo apadera

Nthawi zina, kumwa mankhwala mosamala.

Gwiritsani ntchito mu ukalamba

Assimilation ndi mankhwala a exretion siwosiyana ndi magawo omwewo mwa odwala. Pazifukwa izi, kusintha kwa mlingo sikofunikira.

Kupatsa ana

Kusintha kwa Mlingo sikofunikira.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Pa nthawi yomwe muli ndi pakati, muyenera kuyang'anira kuchuluka kwa shuga m'magazi ndi mkodzo. Kuvutikanso kulikonse kumatha kubweretsa kukula kwa zopunduka, kubadwa kolakwika kapena kufa kwa mwana wakhanda. Popeza mankhwalawa amatha kuyambitsa hypoglycemia, ndizosatheka kumwa mankhwalawa pakubala kwa mwana. Mayi woyembekezera ayenera kusamutsidwa kupita ku insulin.

Glimepiride imadutsa mkaka wa m'mawere, chifukwa cha mankhwala, mkazi ayenera kusamutsa zosakaniza zosakanikirana kwa mwana.

Glimepiride imatha kulowa mkaka wa m'mawere ndipo imatha kusokoneza mwana. Ngati simungakane kulandira chithandizo, mayiyo asinthana ndi mankhwala a insulini ndikugwiritsa ntchito zosakaniza popanga mwana.

The ntchito aimpso kuwonongeka

Mu vuto laimpso, kutenga Dimaril imatsutsana. Wodwala amayenera kusamutsidwa kupita ku insulin.

Gwiritsani ntchito ntchito yolakwika ya chiwindi

Pankhani ya kuphwanya kofatsa, mlingo umasinthidwa payekhapayekha, ndipo pakulandila, ndikofunikira kuwunika momwe thupi limagwirira ntchito. Pamavuto akulu, chithandizo ndi Dimaril chimatsutsana.

Mankhwala ochulukirapo a Dimaril

Wodwala atamwa kwambiri mankhwala, magazi ake amathothoka kwambiri. Matendawa amatenga maola 12 mpaka masiku atatu ndipo amatha kuonekanso pambuyo pothandizidwa. Hypoglycemia imayendera limodzi ndi izi:

  • kupweteka kwa epigastric;
  • kusanza ndi kusanza
  • masomphenya osokoneza;
  • kuchuluka kwa nkhawa;
  • kugwirana chanza;
  • chikomokere
  • kukokana.

Pazizindikiro zoyambirira za hypoglycemia, wodwalayo ayenera kufunsa dokotala nthawi yomweyo.

Kuchokera pa bongo wa Dimaril, kuchuluka kwa shuga kumatsika kwambiri. Pazizindikiro zoyambirira za hypoglycemia, wodwalayo ayenera kufunsa dokotala nthawi yomweyo.

Kuchita ndi mankhwala ena

Musanayambe chithandizo, chisamaliro chimayenera kulipidwa pakulimbana kwa Dimaril ndi mankhwala ena. Kukula kwa glucose kumatha kuphatikizika ndi magulu otsatirawa a mankhwala:

  • estrogens ndi progestogens;
  • thiazide okodzetsa;
  • saluretics;
  • mankhwala omwe amatulutsa chithokomiro ntchito;
  • glucocorticoids;
  • sympathomimetics;
  • adrenaline
  • nicotinic acid;
  • mankhwala othandizira;
  • phenytoin;
  • diazoxide;
  • glucagon;
  • barbiturates ndi rifampicin;
  • acetozolamide.

Ngati wodwala akutenga Dimaril ndi mankhwala ena (mwachitsanzo, zotumphukira za coumarin) nthawi yomweyo, kuphatikiza uku kumatha kuwonjezeka ndikuchepetsa kuchuluka kwa shuga, chifukwa chake ndibwino kugwirizanitsa kugwiritsa ntchito mankhwala ndi dokotala.

Kuyenderana ndi mowa

Ethanol amatha kukweza kapena kutsitsa shuga, koma njirayi ndiyosadalirika. Pazifukwa izi, tikulimbikitsidwa kusiya kumwa mowa kapena kuonana ndi dokotala za kumwa mowa.

Analogi

Ngati simulekerera mankhwalawa kapena mukuyang'ana mankhwala pamtengo wotsika, muyenera kuzolowera zingapo:

  • Glimepiride - kuchokera ku ma ruble 129;
  • Amaril - kuchokera 354 ma ruble .;
  • Diamerid - kuchokera 226 ma ruble.
Glimepiride pa matenda a shuga
Amaril yotsitsa shuga

Musanayambe maphunziro a kuwerenga mosamala malangizo kapena funsani akatswiri omwe akukhudzidwa ndi chithandizo chanu.

Kupita kwina mankhwala

Pamafunika mankhwala kuti mugule mankhwalawo.

Kodi ndingagule popanda kulandira mankhwala?

Dimaril imagawidwa ku pharmacies ndi mankhwala.

Mtengo wa Dimaril

Mtengo wapakati wa mankhwalawo ndi ma ruble 1000.

Zosungidwa zamankhwala

Mankhwalawa amayenera kusungidwa m'malo owuma, otetezedwa ku dzuwa mwachindunji komanso osawonekera kwa ana. Kutentha kosungira - mpaka 25 ° C.

Tsiku lotha ntchito

Zaka zitatu

Wopanga

PJSC "Kievmedpreparat", Ukraine.

Ndikulimbikitsidwa kuti musiye kumwa mowa kapena kuonana ndi dokotala za kumwa mowa.

Ndemanga za Dimaril

Irina, wazaka 29, Kharkov

Mankhwalawa adayikidwa ndi endocrinologist kuti akhalebe ndi shuga. Monga mankhwala ena ambiri, mankhwalawa adayambitsa hypoglycemia ndi zovuta zina. Patsiku lachiwiri la chithandizo, kupweteka m'mimba, nseru. Chifukwa cha izi, ndinasinthira kupita ku insulin Therapy, chifukwa zinali zosatheka kupirira.

Alexander, wazaka 41, Kiev

Dokotala walamula mankhwalawa mtundu wa matenda ashuga a 2. Ntchito mankhwalawa limodzi ndi metformin. Ndimamva kale zotsatira patsiku la 2, palibe mavuto.

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