Zowonetsa ndi malangizo ogwiritsira ntchito Gliclazide MV

Gliclazide ndi imodzi mwazomwe amamwa mankhwala a shuga a mtundu wachiwiri.

Chida ichi chili ndi vuto la hypoglycemic ndipo chimathandizira kuchepetsa kuchuluka kwa shuga m'magazi a wodwala. Mankhwalawa ndi a gulu la zotumphukira za m'badwo wachiwiri.

Zambiri, kapangidwe ndi mawonekedwe ake amasulidwe

Gliclazide MV ndi amodzi mwa mankhwalawa omwe amadziwika kuti amachepetsa shuga. Kuphatikiza pa zotsatira za hypoglycemic, mankhwalawa ali ndi katundu wa antioxidant.

Mankhwalawa ali ndi phindu pa kagayidwe kazakudya mthupi ndipo limalepheretsa kuoneka ngati thrombosis m'matumba ang'onoang'ono, omwe amalumikizidwa ndi mphamvu yake ya hemovascular.

Mu Latin, mankhwalawa ali ndi dzina "Gliclazide". Imapezeka mu mawonekedwe a mapiritsi omwe amafunikira pakamwa. Chidachi chimapezeka ku Russia.

Chofunikira chachikulu cha mankhwalawa ndi Gliclazide. Piritsi limodzi lili ndi pafupifupi 80 mg pazinthu zazikulu. Kuphatikiza apo, calcium stearate imaphatikizidwa ndi microcrystalline cellulose. Komanso pakupanga kwazinthuzo pali lactose monohydrate ndi colloidal silicon dioxide. Povidone amapezeka piritsi ngati adjuvant.

Glyclazide imapezeka m'mapiritsi a 30 ndi 60 mg. Mtundu wa mapiritsiwo ndi oyera kapena otsekemera. Mapiritsiwo ali ndi mawonekedwe a cylindrical, ali ndi chamfer.

Zotsatira za pharmacological

Mankhwalawa ali ndi vuto la hypoglycemic. Mankhwala amathandizira kubisika kwa insulin chifukwa chotenga mbali za cells-cell za kapamba. Pambuyo kuvomereza, odwala adawonetsa kuwonjezeka kwa chidwi cha minofu ya thupi kupita ku insulin.

Gliclazide imalimbitsa minofu ya glycogen synthetase. Mankhwalawa amakhudza kayendedwe ka calcium ions mkati mwa maselo.

Chida chimadziwika ndi pang'onopang'ono hypoglycemic. Mbiri ya glycemic ya wodwalayo imakhala yachilendo mkati mwa masiku awiri kuyambira chiyambi chomwa mankhwala. Mankhwala otengedwa theka la ola chakudya chisanalepheretse kuchuluka kwa shuga mkati mwa chakudya.

Chipangizochi chimathandizira kuti matendawa azikhala mwamphamvu, zomwe zimapangitsa kuchepetsa kufalikira kwa magazi, komanso zimathandizanso kukonzanso. Mankhwalawa amachepetsa njira za zomatira komanso mayanjano a mapulateleti.

Mankhwalawa amachepetsa mwayi wokhala ndi atherosulinosis, amachepetsa chiopsezo cha microangiopathy, retinopathy.

Chida ichi chimathandizira kuchepetsa kukhudzika kwa mitsempha ya magazi pazinthu za adrenaline. Kugwiritsa ntchito nthawi yayitali panthawi ya matenda a shuga a nephropathy kumabweretsa kuchepa kwa mapuloteni mu mkodzo.

Katundu wa mankhwala atsimikiziridwa kuti achulukitsa kuthamanga kwa magazi mwa odwala. Machitidwe a antioxidant amaperekedwa mwa kuchepetsa kuchuluka kwa perrogen lipids m'magazi.

Chogwiritsidwacho chimalimbikitsidwa kwa odwala olemera mopitirira muyeso, popeza akatsatira zakudya, kuphatikizapo kumwa Glyclazide, amachepetsa thupi.

Zizindikiro ndi contraindication kuti mugwiritse ntchito

Mankhwalawa amagwiritsidwa ntchito pazinthu ziwiri:

• mankhwalawa mtundu II matenda a shuga, pamene kudya ndi zolimbitsa thupi samapereka achire zotsatira;
• Ngati njira yochepetsera kuchepetsera chiopsezo cha zovuta mu mawonekedwe a nephropathy, stroke, retinopathy, infarction ya myocardial.

Kulandila mosavomerezeka kwa odwala:

• omwe akudwala matenda ashuga;
• azimayi pamudindo komanso poyamwitsa;
• ntchito kwa chiwindi, impso;
• akudwala ketoacidosis;
• kukhala ndi chidwi chapadera ndi zomwe zimapangidwa ndimankhwala;
• wokhala ndi tsankho lactose kuyambira pakubadwa;
• akudwala matenda a shuga;
• kukhala ndi malabsorption syndrome;
• kutenga phenylbutazone, danazole;
• osakwana zaka 18.

Malangizo ogwiritsira ntchito

Mankhwala amatengedwa kawiri tsiku lililonse pa 80 mg ngati mlingo woyambirira. M'tsogolomu, mlingo umachulukana. Mlingo wamba uli pafupi 160 mg patsiku. Kuthekera kwakukulu ndi 320 mg. Mankhwalawa akulimbikitsidwa kumwa theka la ola musanadye.

Ngati wodwala adaphonya kumwa mankhwalawo, ndiye kuti palibe chifukwa chomwa kumwa mankhwalawa. Pambuyo masiku 14 chithandizo, Glyclazide MV angathe kumwedwa mu 30 mg.

Mankhwalawa amatengedwa kamodzi patsiku chakudya. Mlingo watsiku ndi tsiku utha kukwera mpaka 120 mg.

Kusinthanitsa ndi Gliclazide ndi mankhwala enanso ofananirako sikuyenera kuyenda ndi kupuma. Mankhwalawa amatengedwa tsiku lotsatira.

Mankhwalawa amatha kumwedwa nthawi yomweyo ndi insulin ndi biguanides. Mlingo wovomerezeka umaperekedwa kwa odwala omwe amalephera impso, onse ofatsa komanso odziletsa. Odwala omwe ali ndi chiopsezo chachikulu cha kukhala ndi hypoglycemia ayenera kumwa osachepera mankhwalawa.

Malangizo apadera ndi odwala

Mankhwalawa amatsutsana ndi amayi apakati, komanso amayi oyamwitsa. Mankhwalawa amaleredwa mwa ana osakwana zaka 18.

Kulandila ndikotheka mosamala ndi odwala otsatirawa:

• anthu okalamba;
• ndi zizindikiro za kusakwanira kwa adrenal;
• ndi zakudya zosavomerezeka;
• kwambiri matenda a mtima matenda ndi zizindikiro za atherosulinosis;
• ndi kusowa kwa mahomoni a chithokomiro (hypothyroidism);
• ntchito kwa nthawi yayitali a glucocorticosteroids;
• ndi osakwanira ntchito a hypothalamus, pituitary gland.

Odwala omwe ali ndi vuto laimpso ndi kwa chiwindi ntchito amalephera kumwa mankhwalawa.

Malangizo apadera awa ndi mawonekedwe a mankhwalawa:

• imamwa mankhwalawa a matenda amtundu wa II ndikutsatira zakudya zamafuta ochepa;
• kuvomereza kumafunikira kuwunikira pafupipafupi kuchuluka kwa shuga m'magazi a wodwala pamimba yopanda kanthu;
• vuto la matenda a shuga, mankhwalawa amatha kutengedwa ndi insulin;
• mankhwalawa sayenera kumwa ndi mowa.

Zotsatira zoyipa ndi bongo

Zina mwazotsatira zoyipa mukamamwa mankhwalawa ndi:

• nseru
• zotupa
• kulephera kwa chiwindi;
• kusanza
• mziwindi vasculitis;
• mavuto amawonedwe;
• kuchepa magazi
• kupweteka m'mimba;
• erythropenia;
• kuyabwa
• thrombocytopenia;
• kutsegula m'mimba
• mawonekedwe a anorexia;
• agranulocytosis.

Ndi bongo wambiri, hypoglycemia imatha kupezeka, yomwe imadziwika ndi:

• kufooka
• kuthamanga kwa magazi
• kupweteka mutu;
• kugona
• thukuta
• Chizungulire
• kukokana
• kukoka kwamtima;
• arrhythmia;
• kupezeka kwamavuto amaso;
• zovuta kuyankhula;
• kukomoka.

Hypoglycemia yofatsa komanso yolimbitsa thupi imafuna kuchepetsedwa kwa muyezo wa mankhwala ndi kuyambitsa panthawi yomweyo zakudya zamagulu ochulukitsa azakudya. Pafupipafupi hypoglycemia imafuna wodwala kuchipatala.

Amayikiridwa kudzera m'mitsempha ya glucose 50% ya glucose, ndiye kuti 10% ya glucose imathandizidwa kutsika. Kwa masiku awiri, kuwunika ndende ya magazi kwa wodwala ndikofunikira. Kutsegula m'mimba sikuyenda bwino.

Kuchita ndi mankhwala ena

The munthawi yomweyo Gliclazide ndi mankhwala otsatirawa saloledwa:

• Danazole;
• Cimetidine;
• Phenylbutazone

Kugwiritsa ntchito mogwirizana ndi Verapamil kumafuna kuwunika kwambiri shuga.

Chepetsani kuchepa kwa mankhwala a hypoglycemic:

• okodzetsa;
• ma progestin;
• Rifampicin;
• barbiturates;
• estrogens;
• Diphenin.

Zimathandizira pakukula kwa zotsatira za hypoglycemic ya mankhwala ake munthawi yomweyo:

• Pyrazolone;
• khofi;
• salicylates;
• Theophylline;
• sulfonamides.

Mukamamwa, pamodzi ndi omwe osankhidwa a beta-blockers, wodwala amakhala ndi vuto la hypoglycemia.

Mankhwala okhala ndi vutoli

Mankhwalawa ali ndi fanizo zotsatirazi:

• Diabetes;
• Glidiab MV;
• Diabetesalong;
• Diabefarm MV;
• Diabinax;
• Diabeteson MV;
• Glucostabil;
• Glyclazide-Akos;
• Gliklad.

Maganizo a akatswiri ndi odwala

Kuchokera pakuwunika kwa madotolo ndi odwala omwe akutenga Glyclazide, titha kunena kuti mankhwalawa amachepetsa shuga la magazi ngati zakudya zimatsatiridwa, koma ndikugwiritsa ntchito nthawi yayitali, pali kuwonongeka koyenera. Zotsatira zoyipa zimadziwikanso ndi ena. Ubwino wa mankhwalawo ndiwotsika mtengo.

Gliclazide ndi mankhwala othandiza kwambiri a hypoglycemic. Ngakhale zili ndi zovuta zingapo, mankhwalawa amalekeredwa bwino ndi magulu onse a odwala. Ndikulimbikitsidwa kuti mupereke mankhwalawa mosamala kwa anthu okalamba komanso kuti musamapereke mankhwala nthawi imodzi ndi cimetidine chifukwa chowopsa cha hypoglycemia. Kugwiritsa ntchito mankhwalawa kwakanthawi kumachepetsa kugwira ntchito kwake, komwe kumatsimikiziridwa ndi odwala ambiri. Chipangizocho chimagwira bwino pomwe odwala akutsatira zakudya zapadera zopanda chakudya pang'ono.

Elena, wa zaka 48, endocrinologist

Mankhwalawa adalembedwa ndi dokotala. Ndinganene kuti Gliclazide ndiyothandiza kwambiri. Nthawi zonse ndimayang'ana shuga wanga. Nthawi zonse pamakhala kutsika kwamphamvu kwa chizindikirocho, koma osati kwazomwe zikuchitika, koma pang'ono kuposa pamenepo. Mwa zabwino, munthu amatha kugwiritsa ntchito mtengo wake komanso njira yabwino yolandirira. Zoyipa zazikulu ndizotsatira zoyipa. Nthawi ndi nthawi ndimakhala ndimamva mutu.

Ivan, wazaka 55 zakubadwa

Glyclazide adandiuza kuti azichita ngati dokotala wakale. Mwambiri, mankhwalawa ndiabwino. Zimathandizira kuchepetsa shuga. Ndi mtengo wabwino nthawi yomweyo. Zoyipa zili pamavuto. Ndinkapweteka kangapo m'mimba, mutu. Koma kunalibe zizindikilo zazikulu. Mankhwalawa amathandizanso pakudya zamafuta ochepa.

Veronika, wazaka 65 zakubadwa

Makanema okhudzana ndi mankhwala a Gliclazide ndi momwe amakhudzira thupi:

Mtengo wa mankhwala m'magawo osiyanasiyana ku Russia umachokera ku ruble 115-147 pakiti iliyonse. Mtengo wa ma analogi angapo azandalama amafikira kuchuluka kwa ma ruble 330.