Glucophage ndi mankhwala osokoneza bongo a hypoglycemic omwe amathandiza kwambiri pochiza matenda a shuga a mtundu wachiwiri.
Chidacho chimasintha shuga m'magazi. Amatchuka kwambiri pakati pa odwala onenepa kwambiri.
Zambiri, kapangidwe ndi mawonekedwe ake amasulidwe
Glucofage Long ndi kukonzanso kwa matenda ashuga a kalasi yayikulu ndi yogwira ntchito ya Metformin hydrochloride. Amapezeka mu Mlingo wa 500, 850, 1000 mg.
Ikamamwa, imatha kunyengedwa mwachangu. Kudzikundikira kwakukulu kumachitika pambuyo pa maola 2 pambuyo pa kukhazikitsa.
Izi zimakuthandizani kuti mukwaniritse zotsatirazi:
- matenda shuga;
- onjezani kuyankha kwa minofu ku mahomoni opangidwa;
- kupanga chiwindi m'magazi;
- kuchepetsa kuyamwa kwamatumbo a shuga;
- bweza kulemera kwa thupi kubwerera kwazonse;
- Sinthani kagayidwe ka lipid;
- cholesterol yotsika.
Mapiritsi amagwira ntchito mu prediabetes.
Pogulitsa, mankhwalawa amaperekedwa mwa mawonekedwe a piritsi, yokutidwa ndi chipolopolo cha biconvex cha mtundu woyera. Ndende ya gawo lazogwira ndi 500, 850, 1000 mg. Kuti athandize wodwala, mlingo wa mankhwalawo umalembedwa pa theka la piritsi.
Pharmacology ndi pharmacokinetics
Mapangidwe a mapiritsiwa akuphatikiza Metformin, yomwe imatsimikizira kutchulidwa kwa hypoglycemic. Odwala omwe ali ndi kuchuluka kwa glucose, amachepetsa monga yakhazikika. Mwa anthu omwe ali ndi shuga athanzi, shuga wamagazi amakhalabe osasinthika.
Kuchita kwa chigawo chogwira ntchito kumakhazikitsidwa ndi kulepheretsa kwa gluconeogeneis ndi glycogenolysis, kuthekera kokulimbikitsa chidwi cha insulini komanso kuchepetsa mayamwidwe m'mimba. Kuphatikiza apo, mankhwalawa amathandizira njira zama metabolic m'thupi ndipo amatsitsa cholesterol.
Kuchuluka kwa Metformin kumawonedwa patatha maola 2-3 pambuyo pa kuwongolera. Chizindikiro cha Glucophage Long ndichotsika cha mapuloteni a plasma. Chofunikira chachikulu chimapukutidwa ndi impso ndi matumbo mkati mwa maola 6.5.
Pambuyo potenga Glucofage, adsorption yathunthu ya Metmorphine GIT imadziwika. Gawo lolimbikira limagawidwa mwachangu mthupi lonse. Ambiri amatsitsidwa kudzera mu impso, otsala kudzera m'matumbo. Njira yoyeretsera mankhwalawa imayamba maola 6.5 mutamwa. Odwala omwe ali ndi mavuto a impso, theka la moyo limawonjezeka, zomwe zimawonjezera chiopsezo cha Metformin cumulation.
Zizindikiro ndi contraindication
Malinga ndi malangizo omwe aphatikizidwa ndi Glucofage, akuwonetsedwa ngati anthu odwala matenda ashuga a 2 omwe ali onenepa kwambiri ngakhale atalandira chithandizo chamankhwala.
Odwala ambiri amagwiritsa ntchito Glucofage kuti achepetse thupi. Pankhaniyi, muyenera kutsatira zakudya zochepa zopatsa mphamvu ndikuchita masewera olimbitsa thupi tsiku lililonse. Izi zimakupatsani mwayi wopeza zotsatira zabwino kwakanthawi kochepa.
Monga mankhwala aliwonse, glucophage ali ndi contraindication.
Mankhwala oletsedwa:
- anthu osalolera ku chimodzi mwazigawo;
- ndi coma kapena matenda ashuga ketoacidosis;
- kugwira ntchito molakwika kwa impso ndi mtima;
- ndi kuchulukitsa kwa matenda osachiritsika ndi opatsirana;
- pamodzi ndi nthawi yomweyo zakumwa zoledzeretsa;
- ndi poyizoni thupi;
- pa mimba ndi mkaka wa m`mawere;
- ndi lactic acidosis;
- Masiku awiri pamaso pa radiology ndi masiku awiri pambuyo pake;
- anthu ochepera zaka 10;
- pambuyo pochita masewera olimbitsa thupi.
Kumwa mapiritsi ndi okalamba kumachitika motsogozedwa ndi katswiri.
Malangizo ogwiritsira ntchito
Mlingo woyambira osachepera 500 kapena 850 mg, womwe umagawidwa ma Mlingo angapo. Mapiritsi amatengedwa nawo kapena mukangomaliza kudya. Kusintha kwa mlingo kumachitika pambuyo pa kusintha kwa shuga.
Mlingo wapamwamba kwambiri ndi 3000 mg patsiku, womwe umagawidwanso muyezo waukulu (2-3). Pang'onopang'ono ndende yogwira ntchito m'magazi imachuluka, zotsatira zoyipa zochepa kuchokera m'mimba.
Mukaphatikiza Glucofage Long ndi insulin, mulingo woyenera ndi 500, 750, 850 mg katatu patsiku. Mlingo wa insulin umayendetsedwa ndi adokotala.
Mapiritsi amagwiritsidwa ntchito onse kuphatikiza ndi mankhwala ena, komanso mosiyana. Mwapadera, kuvomerezedwa kuvomerezeka kuyambira wazaka khumi. Mlingo wofotokozedwa ndi dokotala potengera kuchuluka kwa shuga m'magazi. Ochepera ndi 500 mg, okwera ndi 2000 mg.
Odwala Apadera ndi Mayendedwe
Musanagwiritse ntchito mankhwalawa, muyenera kufunsa dokotala, kuphunzira zotsatira zake, ndikuzindikira malangizidwe a odwala omwe ali m'gulu lapadera:
- Nthawi yamimba. Kulandila kwa Glucophage panthawi yokhala ndi mwana ndi kuyamwa kumaletsedwa kotheratu. Mwazi wamagazi umasungidwa mwa kubaya insulin. Kuletsedwa kwa mapiritsi nthawi yoyamwitsa kumachitika chifukwa chosowa kafukufuku.
- Ana m'badwo. Kugwiritsa ntchito shuga kwa ana ochepera zaka 18 sikothandiza. Kodi ali ndi mfundo yogwiritsa ntchito mankhwalawa ndi ana azaka 10? Kuwongoleredwa ndi dokotala ndikofunikira.
- Anthu okalamba. Mosamala, muyenera kumwa mankhwalawa kwa anthu okalamba omwe ali ndi matenda a impso ndi mtima. Njira ya chithandizo iyenera kuyang'aniridwa ndi katswiri.
Matenda ena kapena mikhalidwe, mankhwalawa amatengedwa mosamala, kapena amalephera:
- Lactic acidosis. Nthawi zina, kugwiritsa ntchito Metformin, komwe kumalumikizidwa ndi kupezeka kwa kulephera kwa impso kwa wodwala. Matendawa amayenda ndi kupindika minofu, kupweteka pamimba ndi hypoxia. Ngati nthendayo ikukayikiridwa, kusiya mankhwala ndi kufunsa akatswiri ndikofunikira.
- Matenda a impso. Pa vuto la impso, kusamala kwambiri kuyenera kuchitidwa, popeza thupi limatenga zonse zochotsa Metformin mthupi. Chifukwa chake, musanayambe kugwiritsa ntchito mankhwalawa, chisamaliro chiyenera kulipidwa kufikira mulingo wa creatinine mu seramu yamagazi.
- Opaleshoni. Piritsi amayimitsidwa masiku awiri asanayambe opareshoni. Kuyambiranso kwamankhwala kumayamba pakapita nthawi yofanana.
Kunenepa kwambiri, kumwa mapiritsi kumathandizira odwala matenda ashuga a 2 kuti achepetse kulemera kwawo. Kumbali ya wodwala, kutsatira zakudya zopatsa thanzi kufunikira momwe kuchuluka kwa zopatsa mphamvu kuyenera kukhala osachepera 1000 kcal patsiku. Kupereka mayeso a labotale kumakuthandizani kuti muwone momwe thupi limagwirira ntchito komanso kuchuluka kwa glucophage.
Zotsatira zoyipa ndi bongo
Mndandanda wazotsatira zakumwa za mankhwalawa zimadalira maphunziro ambiri azachipatala komanso kuwunika kwa wodwala:
- Kuchepetsa Vitamini B12 imayambitsa chitukuko cha matenda monga anemia ndi lactic acidosis.
- Sinthani mu masamba a kukoma.
- Kuchokera pamimba, m'mimba, kupweteka pamimba, ndi kusowa kwa chakudya kumawonedwa. Kuchita kumawonetsa kuti chizindikiro chodziwikiratu chimadziwika m'madokotala ambiri ndipo chimadutsa masiku angapo.
- Monga thupi lawo siligwirizana, urticaria ndiyotheka.
- Kuphwanya njira za metabolic kumatha kuyambitsa zochitika zosayembekezereka, chifukwa chomwe kufulumira kwa mapiritsi ndikotheka.
Kuyanjana Ndi Mankhwala Ndi Analogi
Mphamvu ya hyperglycemic ya mankhwala a Danazol imapangitsa kuti ikhale yosatheka kuphatikiza ndi Glucofage. Ngati ndizosatheka kupatula mankhwalawa, mlingo umasinthidwa ndi dokotala.
Ma tinctures okhala ndi mowa amaonjezera ngozi ya lactic acidosis.
Mlingo waukulu wa chlorpromazine (woposa 100 mg / tsiku) amatha kuwonjezera glycemia ndikuchepetsa kuchuluka kwa insulin. Mlingo wa madokotala umafunika.
Kugwirizana kwa okodzetsa kumawonjezera chiopsezo cha lactic acidosis. Sizoletsedwa kutenga Glucofage ndi mlingo wa chini wa 60 ml / min.
Mankhwala okhala ndi ayodini omwe amagwiritsidwa ntchito ngati fluoroscopy kwa odwala omwe ali ndi vuto la impso amayambitsa lactic acidosis. Chifukwa chake, pozindikira wodwala ndi x-ray, kuthetseratu mapiritsi ndikofunikira.
Hypoglycemic zotsatira za mankhwalawa zimatheka ndi sulfonylurea, insulin, salicylates, acarbose.
Ma Analogs amamvetsedwa ngati mankhwala omwe amafunidwa kuti alowe m'malo mwa mankhwala akuluakulu, kugwiritsa ntchito kwawo kumagwirizana ndi dokotala wopezekapo:
- Bagomet. Zopangidwira odwala matenda a shuga a 2 omwe ali ndi kunenepa kwambiri. Ntchito monotherapy komanso osakaniza insulin.
- Glycometer. Mankhwala a mtundu wa 2 odwala matenda ashuga amayamba kunenepa kwambiri. Itha kugwiritsidwa ntchito ngati matenda a shuga 1 kuphatikiza insulin.
- Dianormet. Imathandizira kutulutsa magulu a mahomoni, makamaka kwa odwala omwe ali ndi vuto la mafuta.
Izi zikufanana ndipo ndizotchuka pakati pa odwala matenda ashuga amtundu wa 2.
Malingaliro a Ogwiritsa Ntchito
Kuchokera pakuwunika kwa odwala, titha kunena kuti Glucofage ndiyothandiza kukonza shuga m'magazi, komabe, kugwiritsa ntchito kwake kokha kuchepa thupi sikungapindule, chifukwa makonzedwe amayenda ndi zovuta zingapo.
Kwa nthawi yoyamba yomwe timamva za Glucofage kuchokera kwa agogo athu, omwe ali ndi matenda ashuga a 2 ndipo samatha kutsitsa shuga ndi mankhwala aliwonse. Posachedwa, endocrinologist adamuuza Glucophage kwa muyezo wa 500 mg kawiri pa tsiku. Modabwitsa, kuchuluka kwa shuga kunatsika ndi theka, palibe mavuto omwe adapezeka.
Ivan, wazaka 38, Khimki
Ndimamwa glucophage posachedwa. Poyamba, ndimadwala pang'ono ndipo ndimamva kupweteka m'mimba. Pakatha pafupifupi milungu iwiri zonse zidapita. Mlozera wa shuga unatsika kuchoka pa 8.9 mpaka 6.6. Mlingo wanga ndi 850 mg patsiku. Posachedwa ndidayamba kuyabwa, mwina ndi mlingo waukulu.
Galina, wazaka 42. Lipetsk
Ndimalola Glucofage Long kuti muchepetse kunenepa. Mlingo amasinthidwa ndi endocrinologist. Ndinayamba ndi 750. Ndimadya monga nthawi zonse, koma kulakalaka chakudya kwatha. Ndinayamba kupita kuchimbudzi nthawi zambiri. Zinandichitira ngati nyimbo yotsuka.
Irina, wazaka 28, Penza
Glucophage amatengedwa motsogozedwa ndi katswiri. Awa ndi mankhwala osokoneza bongo a odwala matenda ashuga a mtundu wachiwiri, osati mankhwala ochepetsa thupi. Dokotala wanga anandiuza izi. Kwa miyezi ingapo ndakhala ndikumwa pa 1000 mg patsiku. Miyezo ya shuga imatsika msanga, ndipo ndimayendedwe 2 kg.
Alina, wazaka 33, ku Moscow
Kanema wochokera kwa Dr. Kovalkov okhudza mankhwala a Glucofage:
Mtengo wa glucophage umatengera kuchuluka kwa zomwe zimagwira komanso kuchuluka kwa mapiritsi omwe ali phukusi. Mtengo wocheperako ndi ma ruble 80., Pamwamba kwambiri ndi ma ruble 300. Ndizofunikira kudziwa kuti kusiyana kotereku pamitengo kumatengera mtundu wa bizinesi, chilolezo cha malonda ndi kuchuluka kwa oyimira pakati.