Inulin yolowetsedwa

Chithandizo cha matenda a shuga amtundu 1 sichingatheke popanda insulini, mahomoni omwe nthawi zambiri amapangidwa mokwanira ndi kapamba. Mankhwala obwezeretsanso amakono amatengedwa chifukwa cha luso laubinjiniti ndi sayansi yachilengedwe, pogwiritsa ntchito mabakiteriya osinthika popanga.

Mankhwalawa amadziwika ndi kuyera kwambiri, kuchepa kwa thupi ndi kusinthika kwama pharmacological (mosiyana ndi zinthu zomwe zimachokera pazinthu zopanda pake zomwe zimachokera ku nyama). Huluble insulini ya gululi nthawi zambiri imakhala mbali ya mankhwala osakhalitsa, omwe amakonzedweratu kuti adye musanadye.

Machitidwe a zochita ndi mawonekedwe amawu

Pamene ma insulin opangidwa mwanjira yolowa m'thupi amalowa m'thupi, imalumikizana ndi zolandilira (malembedwe owoneka) a ziwalo zam'mimba ndikupanga "insulin receptor" yovuta. Chifukwa cha izi, kuchuluka kwa shuga kwa glucose kumawonjezeka, ndipo mulingo wake m'magazi aulere, m'malo mwake, umachepa. Kugwiritsa ntchito mtunduwu wa insulin kumayendera limodzi ndi zotsatirapo zabwino mthupi:

• mapuloteni kaphatikizidwe (njira ya mapangidwe) imathandizira;
• insulin kukana kumachepa;
• Kuwonongeka kwa glycogen m'chiwindi kumachepa, chifukwa chomwe glucose samadyedwa mwachangu kwambiri ndipo mulingo wake m'magazi umakwera pang'onopang'ono.

Insulin iyi ingagwiritsidwe ntchito ngati mankhwala okhawo ochizira odwala matenda a shuga kapena kuphatikiza ndi mankhwala ena. Pofuna kupewa kuwonda kwa mafuta onunkhira (lipodystrophy), ndibwino kusintha nthawi iliyonse kuti mupeze jakisoni.

Mankhwala obayidwa amayenera kukhala osachepera kutentha, osabala ndipo zida za payekha ziyenera kugwiritsidwa ntchito pobayira

Zizindikiro

Ma insulin omwe amakhala ndi chibadwa cha anthu amapezeka kwambiri pochiza matenda amtundu woyamba. Komanso zizindikiritso zoyambitsa zake zitha kukhala izi:

Biphasic Insulin Aspart

• lembani matenda ashuga a 2 a shuga ndi njira yovuta, yomwe singathe kuwongolera ndi zakudya komanso mankhwala ochepetsa shuga;
• zovuta pachimake matenda amtundu uliwonse (ketoacidosis, hyperglycemic chikomokere);
• kubadwa kwa ana ndi opaleshoni kwa odwala omwe akudwala matenda a metabolic;
• matenda ashuga gestational (vuto lakudya).

Ngati wodwala yemwe anali ndi matendawa anali ndi matenda ashuga asanatenge pakati ndipo adagwiritsa ntchito insulin iyi chithandizo, amatha kupitilirabe mankhwalawa. Koma ziyenera kukumbukiridwa kuti ndi kubereka kwa mwana wosabadwayo, kufunikira kwa timadzi timene timasintha, motero dokotalayo ayenera kusintha mankhwalawo ndikusankha mtundu woyenera wa jekeseni. Mankhwalawa atha kugwiritsidwanso ntchito poyamwitsa ngati mayi akufunika chithandizo cha insulin, koma lingaliro lotere lingachitike ndi dokotala, poganizira chiopsezo cha mayi ndi mwana.

Zotsatira zoyipa ndi contraindication

Insulin yaumunthu yomwe imapezeka pogwiritsa ntchito njira zachilengedwe, makamaka, imalekeredwa bwino ndi odwala ndipo sizimayambitsa zovuta zilizonse. Koma, monga mankhwala ena aliwonse, mowiriza iwo angayambitse kukulitsa zotsatira zosakhudzidwa ndi ziwalo zosiyanasiyana.

Zotsatira zoyipa zimaphatikizapo:

• hypoglycemia (kutsitsa magazi m'munsi mwa chizolowezi cha thupi);
• kutopa, kusokonezeka kwa kugona;
• kukomoka;
• redness ndi kuyipa kwa khungu pamalo jakisoni;
• hyperglycemia (ndi mulingo wosankhidwa wosayenera, kuphwanya zakudya kapena kudumphira jakisoni);
• kutupa;
• lipodystrophy.

Odwala omwe sanalowetse insulin m'mbuyomu amatha kukumana ndi mavuto am'maso kumayambiriro kwa chithandizo.

Monga lamulo, vuto la ophthalmic ndi losakhalitsa, ndipo limazimiririka patatha milungu iwiri. Amalumikizidwa ndi kuphatikizika kwa shuga wamagazi ndi kulephera kwa mitsempha yaying'ono ya m'magazi a retina kuti azolowere kusintha kumeneku. Ngati masomphenya akupitilizabe kugwa, kapena osachira pakatha mwezi umodzi kuchokera pomwe adayamba kulandira chithandizo, wodwalayo ayenera kuwona ndi ophthalmologist kuti amupime mwatsatanetsatane.

Mankhwalawa sanatchulidwenso chifukwa cha chiwindi chachikulu cha hepatitis, kuphwanya kwambiri chiwindi ndi impso, kuwonongeka kwa mtima. Mosamala, chida ichi chimagwiritsidwa ntchito pangozi zamatumbo, matenda a chithokomiro komanso kulephera kwa mtima. Ngati wodwala matenda ashuga amatenga mankhwala nthawi yomweyo kuti achepetse magazi, ndikofunikira kudziwitsa endocrinologist za izi, popeza kuphatikiza kwa insulin ndi ena mwa iwo kungayambitse kukula kwa hypoglycemia.

Kugwiritsa ntchito insulin, komwe kumachitika chifukwa cha luso lamakono opanga majini, kumapewa zovuta zambiri za matenda ashuga. Mankhwalawa amapita pamiyeso ingapo yoyeretsa, kotero ndi otetezeka ngakhale kwa omwe ali ndi matendawa komanso odwala matendawa. Koma, ngakhale utapeza phindu lililonse pamankhwala, ndizosatheka kungoyerekeza ndikugwiritsa ntchito mosagwiritsa ntchito mankhwala a dokotala. Ngakhale kusintha kwa mtundu wina wa insulin kupita ku wina kumatha kuchitika pokhapokha kukaonana ndi endocrinologist ndi mayeso odutsa. Izi zimapewa zovuta zosasangalatsa ndikuwonetsetsa kuti mankhwalawa agwira bwino kwambiri.