Mankhwala a insulin - kukhazikitsidwa kwa mankhwala omwe amachokera ku insulin pazolinga zochizira. Pali mitundu yambiri ya mankhwala kutengera ndi mahomoni awa, omwe amagawidwa m'magulu angapo kutengera nthawi yomwe mavutowo amayambira komanso nthawi yomwe akuchitapo kanthu. Mmodzi mwa oimira mankhwala a nthawi yayitali ndi Insulin --isophane. Werengani zambiri za momwe amagwiritsidwira ntchito munkhaniyi.
Zotsatira za pharmacological
Insulin-isophan (umisiri wamtundu wa chibadwa cha anthu) imapangidwa ndikusintha DNA ya mahomoni powonjezera mtundu wa bowa wa unicellular omwe ali m'gulu la saccharomycetes. Polowa m'thupi, chinthucho chimapanga ma cell enaake pama cell omwe amachititsa kuti maselo ena azituluka, kuphatikizapo kapangidwe kazinthu zofunika.
Hypoglycemic effect ya Insulin-isophan imalumikizidwa ndi kuthamanga kwa magwiridwe a shuga omwe amachokera mumagazi kulowa m'maselo a thupi la munthu, komanso kuchepa kwa kapangidwe ka shuga ndi chiwindi hepatocytes. Komanso, mankhwalawa amathandizira kupanga mapangidwe a mapuloteni, amatenga nawo mbali mu metabolism yamafuta.
Kutalika kwa vuto pambuyo pakupereka mankhwalawa kumatengera mayamwidwe ake, omwe, amatsimikizika pazinthu zingapo:
- Mlingo wa chinthu;
- njira yoyendetsera;
- malo oyambitsa;
- mkhalidwe wamthupi la wodwalayo;
- kukhalapo kwa matenda ophatikizika (makamaka opatsirana);
- zolimbitsa thupi;
- kuchuluka kwa thupi la wodwalayo.
An endocrinologist ndi katswiri yemwe angakuthandizeni kusankha njira ya insulin
Malinga ndi ziwerengero, ntchito ya Insulin-isophan imawonekera pambuyo pa maola 1.5 kuchokera nthawi yomwe jakisoni, nthawi yayitali ya maola pafupifupi 24. Mulingo wamphamvu kwambiri m'magazi umawonedwa kuyambira maola 2 mpaka 18 pambuyo pa kuperekedwa kwa mankhwala pansi pa khungu.
Mankhwalawa samadutsa mkaka mukamayamwitsa. Mpaka 75% ya chinthucho amuchotsa mkodzo. Malinga ndi kafukufuku, mankhwalawa sakhala poopsa pakubala komanso DNA ya munthu, ilibe vuto lililonse.
Kodi chinthucho chimapangidwira liti?
Malangizo ogwiritsira ntchito akuwonetsa kuti zomwe zikuwonetsa kugwiritsa ntchito Insulin-isophan ndi:
Njira ya Inulinion ya Insulin- mawonekedwe a shuga a insulin;
- osachiritsika omwe amadalira shuga;
- kukana gawo la mapiritsi kuchepetsa shuga;
- kukhalapo kwa matenda omwe amagwirizana (omwe amalumikizana mwangozi, koma ochulukitsa zomwe zimayambitsa matenda);
- shuga ya amayi apakati.
Njira yogwiritsira ntchito
Kutulutsidwa kwa mankhwalawa ndikuyimitsa jakisoni wa 40 IU mu 1 ml. Botolo ili ndi 10 ml.
Isulin insulin imagwiritsidwa ntchito ngati jekeseni wofunda. Mlingo wake umasankhidwa ndi katswiri wodziwikiratu, kuganizira za jenda, zaka za wodwalayo, kulemera kwake, zisonyezo za shuga ndi zochitika zolimbitsa thupi. Monga lamulo, 0,5-1 IU patsiku imayikidwa pa kilogalamu imodzi yakulemera kwa thupi.
Mankhwala atha kuperekedwa:
- pa ntchafu;
- matako;
- khomo lam'mimba lakunja;
- minyewa yotsekemera ya phewa.
Mankhwala amaperekedwa pokhapokha, osinthira malo a jekeseni
Malowa amafunika kusinthidwa nthawi zonse. Izi ndizofunikira popewa kukula kwa lipodystrophy (mkhalidwe womwe subcutaneous mafuta wosanjikiza atrophies).
Kuchita insulin mankhwala ogwiritsa ntchito Insulin-Isophan, monga mankhwala ena aliwonse ofanana ndi pancreatic hormone analogue, ayenera kuphatikizidwa ndikuwunika kuchuluka kwa glycemia mu mphamvu.
Mlingo wa mankhwalawa uyenera kusinthidwa motere:
- aakulu kusakwanira kwa adrenal kotekisi;
- hypothyroidism;
- kwambiri matenda a impso kapena chiwindi;
- matenda opatsirana omwe amayenda ndi kutentha kwambiri kwa thupi;
- ukalamba wa wodwala.
Contraindication ndi zoyipa
Isulin insulin sinafotokozeredwe mankhwala a insulin pamaso pa anthu pakumverera kwawonjezeka, pamaso pa chotupa cha pancreatic cha mahomoni komanso kuchepa kwa glycemia.
Kukhazikitsidwa kwa mankhwala okulirapo kuposa momwe kungafunikire kungayambitse matenda a hypoglycemic. Mawonetseredwe ake apakati ndi mutu ndi chizungulire, malingaliro amanjala, kugona thukuta kwambiri. Odwala amadandaula za manja akunjenjemera, zala, mawonekedwe a nseru ndi kusanza, mantha komanso malingaliro.
Zofunika! Mukamawunika, kukumbukira kumatha, kulumikizana, kusokonezeka kwa malo, komanso kuyankhula.
Hypoglycemia - shuga m'magazi ochepa omwe amayamba chifukwa cha kuchuluka kwa mahomoni a pancreatic
Kuphatikiza pa mankhwala osokoneza bongo ambiri, zomwe zimapangitsa kuti pakhale glycemia wocheperako zimatha kudumphira chakudya chotsatira, ndikusintha kukonzekera kwa insulini ina, kuchita masewera olimbitsa thupi, kusintha malo oyang'anira, munthawi yomweyo ndimagulu angapo a mankhwala.
Zotsatira zina zoyipa zomwe zingachitike chifukwa chosagwirizana ndi dongosolo la mankhwalawa kapena mtundu wosankhidwa molakwika umatha kukhala vuto la hyperglycemic. Zizindikiro zake zimawoneka motere:
- wodwala nthawi zambiri amamwa ndikuwonetsa mkodzo;
- kupumirana mseru ndi kusanza;
- Chizungulire
- khungu louma ndi mucous nembanemba;
- kumverera kwa fungo la acetone mu mpweya wotuluka.
Mankhwalawa amathanso kuyambitsa mavuto omwe amayambitsidwa ndi ma syndromes otsatirawa:
- urticaria;
- Edema ya Quincke;
- anaphylactic mantha.
Patsamba la jakisoni, edema, njira yotupa, redness, kuyabwa, hemorrhage, ndi lipodystrophy zimatha.
Palinso zochitika zina zomwe kugwiritsa ntchito Insulin-isophan kumaphwanya luso loyendetsa magalimoto ndi zina. Izi zitha kukhala chifukwa chogwiritsa ntchito kwambiri mankhwalawa, kusintha kuchoka pamtengo wina kupita kwina, zomwe zimapangitsa kupsinjika, komanso ndi zochitika zolimbitsa thupi.
Nthawi zina, chizungulire chimayamba, chomwe chimalepheretsa kuyendetsa magalimoto.
Mimba komanso kuyamwa
Zomwe zimagwiritsidwa ntchito ndi mankhwalawa sizilowa mkaka wa m'mawere komanso kudzera mu zotchinga, chifukwa chake, insulin-isofan imatha kupatsidwa kwa azimayi panthawi yakumwa ndi kuyamwitsa. Ndikofunika kuwerengera molondola mlingo wa mankhwala omwe waperekedwa chifukwa chiwonjezero chambiri kapena kuchepa kwa shuga m'magazi a amayi mukamagwiritsa ntchito mlingo woyenera umadzala ndi mwana wosabadwayo.
Kuyanjana kwa mankhwala osokoneza bongo
Pali mankhwala omwe amatha kupititsa patsogolo zotsatira za hypoglycemic za Insulin-isophan, koma pali zina zomwe, m'malo mwake, zimafooketsa, zomwe zimapangitsa kuti magazi a wodwala azikula.
Gulu loyamba la mankhwalawa limaphatikizapo:
- zolemba hypoglycemic;
- ACE zoletsa;
- sulfonamides;
- maantibayotiki ena;
- anabolic steroids;
- othandizira antifungal;
- Theophylline;
- Kukonzekera-kokhala ndi lifiyamu;
- Clofibrate.
Oimira gulu la tetracycline amatha kupititsa patsogolo zotsatira za insulin
Gulu lachiwiri limaphatikizapo:
- mahomoni a adrenal cortex;
- Ma COC;
- mahomoni a chithokomiro;
- heparin;
- okodzetsa
- antidepressants;
- amphanomachul.
Mayina amalonda
Isulin insulin ndi chinthu chogwiritsidwa ntchito pa mitundu yambiri ya insulin yaumunthu, motero dzina lake la malonda lili ndi mitundu ingapo
- Biosulin-N;
- Protafan NM;
- Protafan NM Penfill;
- Rosinsulin C;
- Humodar B Mitsinje 100;
- Humulin NPH.
Insulin imadziwika kuti ndi mankhwala. Kudzilanga nokha ndi chida chotere ndikosavomerezeka.
