Maselo ochepera kulemera kwa heparins (LMWH) ndi gulu la mankhwala anticoagulant omwe amagwiritsidwa ntchito poletsa komanso kuchiza zovuta za thromboembolic.
Mitundu yamapulogalamu imakhala yotakata, kuphatikiza mawonekedwe opangira opaleshoni ndi achire, komanso mankhwala azadzidzidzi.
Mosiyana ndi omwe adatsogolera, Heparin, LMWH adanenanso kuti zochita zamankhwala ndizotetezedwa, ndizotetezeka komanso zowongolera, zitha kutumizidwa popanda kugwiritsidwa ntchito kapena kudzera m'mitsetse.
Masiku ano, mibadwo ingapo ya mankhwalawa imaperekedwa pamsika, womwe umathandizidwa nthawi zonse ndi mankhwala atsopano. Nkhaniyi iyang'ana kwambiri za Fraxiparin, mtengo ndi mtundu wake womwe umakwaniritsa zofunikira za madotolo ndi odwala.
Zizindikiro
Fraxiparin yogwira ndi calcium nadroparin, yomwe ikuwonetsedwa pazotsatira zotsatirazi:
- kupewa thrombosis odwala ndi opaleshoni mbiri;
- mankhwalawa pulmonary embolism;
- mankhwalawa thrombophlebitis zosiyanasiyana zoyambira;
- kupewa magazi kuundana pa hemodialysis;
- mankhwalawa pachimake coronary syndrome (kugunda kwa mtima).
Ndikofunikira kudziwa kuti Fraxiparin imagwiritsidwa ntchito makamaka kuchipatala moyang'aniridwa ndi dokotala. Asanachitike, maphunziro azachipatala ndi a labotale, makamaka coagulogram, akuyenera kuchitidwa.
Contraindication
Palibe mankhwala omwe ndi oyenera kwa odwala onse.
Musanagwiritse ntchito, muyenera kuwerenga mosamala malangizo ndikuona ngati muli ndi zotsatirazi:
- thupi lawo siligwirizana ndi nadroparin calcium kapena zinthu zina zothandiza zomwe zili mbali ya yankho;
- thrombocytopenia;
- kuthamanga magazi kapena chiwopsezo cha kukula kwake;
- kuvulala kwamkati muubongo;
- mimba ndi mkaka wa m`mawere;
- kulephera kwambiri kwaimpso;
- ana osaposa zaka 18 (cholakwika ndi wachibale).
Mosiyana ndi Heparin, yemwe ali ndi mankhwala achilengedwe - Protamine sulfate, LMWH satero.
Kutulutsa Fomu
Fraxiparin imapezeka ngati yankho la subcutaneous kapena mtsempha wamkati. Zimapezeka mu ma syringe osindikizidwa omwe ali ndi chipewa choteteza, chomwe chimadzaza bwino pazidutswa 10 phukusi.
Yothetsera subcutaneous makonzedwe a Fraxiparin
Nthawi zambiri amapaka jekeseni pang'ono, chifukwa, syringe imachotsedwa kuchokera kumimba ndipo chipewa chimachotsedwa. Tsamba la jakisoni (dera la umbilical) limachizidwa katatu ndi antiseptic.
Khola limapangidwa ndi zala zakumanzere, singano imayilidwa zolimba pakhungu nthawi yonseyo. Syringe imachotsedwa, siyabwino kuyigwiritsanso ntchito.
Wopanga
Fraxiparin ndi mankhwala odziwika kuchokera ku kampani yopanga mankhwala ku America Aspen.Kampaniyi yakhala ikuyenda pamsika kwa zaka zoposa 160, malinga ndi 2017, ndi ena mwa atsogoleri khumi padziko lonse akupanga mankhwala, zida zamankhwala ndi ma labotale.
Makampani aku France a Sanofi-aventis ndi Glaxosmithkline amapereka mitundu yosiyanasiyana ya calcium nadroparin, yemwenso ili ndi dzina la malonda Fraxiparin.
Mwanjira iyi, mankhwalawa ndi generic (adagula ufulu wopanga kuchokera ku Aspen). Ku Ukraine, Nadroparin-Farmeks ikupezeka kuti ikugulitsidwa, yomwe imapangidwa ndi gulu la Pharmex.
Kulongedza
Amapezeka mu syringes zotayika za 0,3, 0,4, 0,6 ndi 0,8 ml, zidutswa 10 paphukusi limodzi.
Mlingo wa mankhwala
0,3 ml
Mlingo umatengera kuzungulira kwa yogwira mankhwala - calcium nadroparin, yoyesedwa m'mayunitsi apadziko lonse lapansi.
1 ml ya Fraxiparin ili ndi 9500 IU ya yogwira.
Chifukwa chake, mu 0.3 ml adzakhala 2850ME. Mu kuchuluka kumeneku, mankhwalawa amawonetsedwa kwa odwala omwe kulemera kwawo sikupitirira 45 kg.
0,4 ml
Muli 3800 IU ya nadroparin calcium, akuwonetsedwa kwa odwala olemera 50 mpaka 55 kg.
0,6 ml
Muli mankhwala othandizira 5700ME, oyenera odwala kuchokera 60 mpaka 69 kg.
Mtengo
Mtengo wa Fraxiparin umatengera mlingo komanso wopanga. Palibe amene anena kuti mtundu wodziwika ndiwodula kwambiri kuposa mankhwala.
Mtengo wa Fraxiparin, kutengera mtundu wake:
Mlingo wa ml | Mtengo wapakati ku Russia mu ma ruble a ma syringe 10 |
0,3 | 2016 ― 2742 |
0,4 | 2670 ― 3290 |
0,6 | 3321 ― 3950 |
0,8 | 4910 ― 5036 |
Mitengo imakhala pakati, yoperekedwa kwa 2017. Zitha kusiyanasiyana ndi dera komanso mankhwala.
Makanema okhudzana nawo
About the endombophlebitis mu shuga mu kanema:
Chifukwa chake, Fraxiparin ndi mankhwala ofunikira othandizira komanso kupewa matenda a thrombosis. Zina mwazabwino ndi mitundu ya mitundu yomwe ilipo, chitetezo ndi mtengo wokwanira.