Nzosadabwitsa kuti matenda ashuga amatchedwa matenda a zaka zana lino. Kuchuluka kwa odwala omwe ali ndi vutoli kukukulira chaka chilichonse.
Ngakhale zomwe zimayambitsa matendawa ndizosiyana, chibadwidwe ndichofunika kwambiri. Pafupifupi 15% ya odwala onse amadwala matenda amtundu woyamba. Mankhwala amafunika jakisoni wa insulin.
Nthawi zambiri, zizindikiro za matenda amtundu 1 zimawonekera paubwana kapena kuubwana. Matendawa amadziwika ndi kukula kwake mwachangu. Ngati zinthu sizikutsatiridwa munthawi yake, zovuta zimatha kubweretsa kusokonekera kwa machitidwe amodzi payekha, kapena thupi lonse.
Kugawa insulin kungachitike pogwiritsa ntchito Humalog, fanizo la mankhwalawa. Mukamatsatira malangizo onse a dokotala, wodwalayo amakhala wodekha. Mankhwala ndi analogue a insulin ya anthu.
Pamaapangidwe ake, ma DNA okumba amafunikira. Ili ndi mawonekedwe - imayamba kuchita zinthu mwachangu (pasanathe mphindi 15). Komabe, kutalika kwa zochita sikupitirira 2-5 mawola atalandira mankhwalawa.
Wopanga
Mankhwalawa amapangidwa ku France. Alinso ndi dzina lina lapadziko lonse - Insulin lispro.
Chofunikira chachikulu
Mankhwalawa ndi njira yopanda utoto yoyatsidwa yoikidwa m'makatolo (1.5, 3 ml) kapena Mbale (10 ml). Imaperekedwa kudzera m'mitsempha. Chithandizo chogwira mankhwalawa ndi insulin lispro, kuchepetsedwa ndi zina zowonjezera.
Zowonjezera zina zikuphatikiza:
- metacresol;
- glycerol;
- zinc oxide;
- sodium hydrogen phosphate;
- 10% hydrochloric acid solution;
- 10% sodium hydroxide solution;
- madzi osungunuka.
Analogs popanga
Zowonjezera m'malo ndi:
- Humalog Remix 25;
- Lyspro insulin;
- Kusintha kwa Humalog 50.
Analogs mwa chisonyezo ndi njira yogwiritsira ntchito
Malonda a mankhwalawa malinga ndi momwe akuwonetsera ndi njira yake ndi:
- mitundu yonse ya Actrapid (nm, nm penfill);
- Biosulin P;
- Insuman Rapid;
- Humodar r100r;
- Farmasulin;
- Humulin pafupipafupi;
- Gensulin P;
- Insugen-R (Wokhazikika);
- Rinsulin P;
- Monodar;
- Farmasulin N;
- NovoRapid Flexpen (kapena Penfill);
- Epidera;
- Apidra SoloStar.
Analogs ATC Level 3
Mankhwala opitilira atatu omwe ali ndi mawonekedwe osiyanasiyana, koma ofanana ndi mawonekedwe, njira yogwiritsira ntchito.
Mayina ena ofanana ndi Humalog omwe adalembedwa ndi code yachitatu ya ATC:
- Biosulin N;
- Insuman basal;
- Protafan;
- Humodar b100r;
- Gensulin N;
- Insugen-N (NPH);
- Protafan NM.
Kusintha kwa Humalog ndi Humalog 50: kusiyana
Ena odwala matenda ashuga molakwika amalingalira kuti mankhwalawa ndi othandizira kwathunthu. Izi siziri choncho. Prostamine Hagedorn (NPH) yosalowerera ndale, yomwe imachepetsa kuchitira insulin, imayambitsidwa mu Kusakaniza kwa Humalog 50.
Zowonjezera zowonjezera, ndizowonjezera jakisoni. Kutchuka kwake pakati pa odwala matenda ashuga ndi chifukwa chakuti amachepetsa njira ya insulin.
Humalog Sakanizani ma cartridge 50 100 IU / ml, 3 ml mu syringe yotentha
Chiwerengero cha tsiku ndi tsiku cha majekeseni amachepetsedwa, koma si odwala onse omwe amapindula. Ndi jakisoni, nkovuta kupereka njira zabwino zowongolera shuga. Kuphatikiza apo, ndale ya protamine Hagedorn nthawi zambiri imayambitsa zovuta zomwe zimayambitsa matenda ashuga.
Nthawi zambiri, insulin yomwe imatenga nthawi yayitali imaperekedwa kwa odwala okalamba, omwe, chifukwa cha ukalamba, amayiwala kupanga jakisoni panthawi.
Humalog, Novorapid kapena Apidra - ndibwino?
Poyerekeza ndi insulin yaumunthu, mankhwalawo pamwambapa amalandiridwa mochita kupanga.Mitundu yawo yosinthika imapangitsa kuti achepetse shuga mwachangu.
Insulin yaumunthu imayamba kuchita theka la ola, mankhwala ake omwe amafananizira zomwe angachite azingofunika mphindi 5-15 zokha. Humalog, Novorapid, Apidra ndi mankhwala a ultrashort omwe amapangidwa kuti achepetse shuga.
Mwa mankhwala onse, wamphamvu kwambiri ndi Humalog.. Imachepetsa shuga m'magazi 2,5 kuposeranso insulin yayifupi ya munthu.
Novorapid, Apidra ndiwofooka pang'ono. Ngati mungayerekeze mankhwalawa ndi insulin ya anthu, zimapezeka kuti ali ndi mphamvu nthawi 1.5 kuposa mphamvu zotsalazo.
Makanema okhudzana nawo
Pazinthu zomwe mungagwiritse ntchito insulin Humalog mu kanema:
