Metformin pakukulitsa kwa mankhwalawa a matenda ashuga a 2

Metformin ndi muyezo wagolide wofunikira pazigawo zonse za kukulitsa kwa chithandizo cha matenda a shuga a 2. Ngakhale zinali zofanana ndi zosiyana pamalingaliro, patadutsa zaka makumi angapo, adasintha kwambiri momwe amathandizira odwala matenda ashuga amtundu wa 2.

Msika wamakono wamankhwala uli ndi magulu khumi amankhwala omwe amapangidwa kuti athetsere matenda ashuga a 2, koma Metformin, monga wophunziridwa kwambiri komanso wogwiritsidwa ntchito kwambiri konsekonse pamatendawa matenda.

Awa ndi mankhwala okhawo omwe amadziwika kuti amapambana mu monotherapy, kuwonjezereka sikulinso kwina. Kodi nchifukwa ninji anayenera kutchuka chotere?

Metformin ndi mankhwala okwera mtengo komanso okhala ndi umboni wamphamvu: ngati mungafufuze pa database ya Pubmed pazaka khumi zapitazi, mutha kupeza zolemba zambirimbiri zomwe zimafufuza kwambiri za Metformin popewa komanso kuchiza matenda amtundu wa 2 matenda, mtundu wa antitumor ndi zotsatira za mtima.

Kafukufuku wachipatala adawonetsa kuti kugwiritsa ntchito Metformin pafupipafupi kumachepetsa ndi kufa kwachitatu, kufa chifukwa cha kulowetsedwa ndi matenda osokoneza bongo, kumathandizira kupulumuka kwa odwala khansa ndikuchepetsa mwayi wokhala ndi khansa ya m'mawere m'matenda a matenda ashuga. Kuphatikiza apo, mankhwalawa amatulutsa mphamvu yoletsa kudya kwa caloric, njira yodalirika kwambiri yotalikitsa moyo.

Njira zoteteza za Metformin

Kodi chimayambitsa matendawa ndi chiyani?

1. Mankhwala amapangitsa insulin kudziwa;
2. Amathandizira kuwongolera glycemic;
3. Mitengo ya Fibrinolysis ikupita patsogolo;
4. Microcirculation mu zotumphukira zimakhala zimagwira;
5. Endothelial kukanika kumachepa;
6. Potengera maziko a metformin, hyperglycemia imachepa;
7. Kupanga kwa glycation kumapeto kwa zinthu kumatsitsidwa;
8. Kachulukidwe ka magazi kumaundana;
9. Kupanikizika kwa Oxidative sikungokhala;
10. Zothandiza pa atherogenesis ndi dyslipidemia.

Mankhwalawa amachepetsa chiopsezo cha zochitika za mtima ndi matenda ashuga omwe ali ndi mtundu wachiwiri wa matenda, ndipo zotsatira za kukumbukira kwa metabolic zimakuthandizani kuti musunge zotsatira kwanthawi yayitali.

Chithandizo ndi Metformin ndi zotumphukira zake zimachepetsa kwambiri glycemia.

Poyerekeza ndi analogues ndi mankhwala ena osokoneza bongo, Metformin imathandizira kulemera ndipo imathandizira kuchepetsa.

Kafukufuku wazaka zisanu zaku China wazaka zisanu, zomwe zidakhudza odwala matenda ashuga 6,800 omwe ali ndi vuto lachiwiri popanda mbiri ya matenda amtima, adawonetsa kuti m'gululi pomwe omwe akuchita nawo kafukufukuyu adatenga metformin kuwonjezera pa kusintha kwa moyo, kumwalira kunali milandu 7.5 pa Anthu 1000 / zaka (kwa miyezi 62,5).

Pulofesa E. Malysheva amalankhula za kuthekera kwa Metformin mu kanema:

Mankhwala ofanana ndi mayina ogulitsa

Bizinesi yamankhwala ndi imodzi mwazopindulitsa kwambiri, ndipo kampani yokha yaulesi yopanga mankhwala okhala ndi metformin yogwira. Masiku ano, palinso mankhwala ofanana ndi mitundu ingapo - kuchokera ku dzina la brand kupita ku bajeti yambiri.

Mankhwala oyamba ali ndi dzina lapadziko lonse - metformin hydrochloride. Mankhwala kuchokera pagulu la ma biagunides, m'gulu lino la mankhwala akadali amodzi. Zina zonse zomwe timapeza mu pharmacy network ndi mayina amalonda amakampani omwe amatulutsa metformin yomweyo.

Pamene wothandizira kapena endocrinologist akapatsa wodwala matenda ashuga, Metformin adzawonetsedwa pamenepo.

Kampani iti yomwe ingakhale mankhwalawo zimatengera gawo logulitsira komanso mabungwe olamulira omwe amasayina kuloleza kukhazikitsa mtundu wina wa mankhwala.

Mwachitsanzo, mabungwe olamulira alowa mu mgwirizano ndi Akrikhin. Chifukwa chake, mu mankhwalawa mudzapatsidwa Glyformin (a genformin a Metformin), osati Glyukofazh (woyambayo). Kotero kuti kumuimba mlandu dokotala kuti akupereka mapiritsi “olakwika” kulibe ntchito - uku si luso lake. Fomuyi ikuwonetsa dzina losakhala laudindo.

Mankhwala atsopano asanalowe mu netiweki yogawa, zimatenga mpaka zaka 10. Nthawi yonseyi, Metformin idafufuzidwa ndi kampani imodzi yopanga mankhwala omwe amapanga zoyambira. Mtsogolomo, monga lamulo, amagulitsa patent yopanga mankhwala kwa aliyense. Mankhwala operekedwa ndi makampani awa amatchedwa ma generics.

Zoyambirira zimasiyana ndi zonse mu mtengo komanso mtengo, chifukwa Metformin idaphunziridwa bwino momwe amapangidwira, kuphatikiza kapangidwe kazigoba ndi ena ojambula. Mitundu yamagetsi imamasulidwa ndi zowonjezera zina zomwe sizinadutse zaka zambiri zakufufuza, zomwe zikutanthauza kuti kuthekera kwawo kudzatsikira.

Mankhwala oyamba amatchedwa Glucophage, ndipo amapangidwa ku France. Metformin ili ndi mitundu yambiri, koma ogula ambiri amakonda:

• German Siofor;
• Argentine Bagomet;
• Croatia formin pliva;
• Domestic Gliformin;
• Metfogamme waku Germany;
• Russian Formethine;
• Patriotic Novoformin;
• Serform Metformin;
• Russian Metformin Richter;
• Israeli Metformin Teva.

Pali mankhwala ambiri mu netiweki yogawidwa ndi mizu yaku China kapena India, ndipo azikhala otsika mtengo kwambiri kuposa omwe alembedwa, koma kugwira ntchito kwawo kumafanana ndi mtengo. Pa Metformin, mtengo wophatikizira mankhwala amapanga kuchokera ku 94 mpaka 287 ma ruble ndipo zimatengera mlingo, kampani, ndi kuchuluka kwa mapiritsi.

Zosiyanasiyana za mtundu wa Metformin wopitilira nthawi yayitali monga Glucofage. Nthawi zambiri, mankhwala ophatikizika a metformin amagwiritsidwa ntchito mwanjira zopangira mankhwala osakanikirana - Gluconorm, Glucovans, Glibomet, Galvus Mete, Yanumet, Amarile M ndi ena. Iwo omwe amalandira mankhwalawo kwaulere alibe njira, koma ngati thanzi ndi lokwera mtengo kuposa ndalama ndipo pali chisankho, yang'anirani mlingo wake.

Njira zowonetsera mankhwala osokoneza bongo

Metformin ya antidiabetesic ili ndi katundu wochepetsa shuga, zomwe zikutanthauza kuti sizingalimbikitse kupanga kwa insulin komanso insulin yodzaza matumba, yomwe imagwira kale ntchito moyenera.

Chachikulu zotumphukira mankhwala:

1. Imachepetsa kukula kwa basal glycemic mwa kuwongolera kutulutsidwa kwa glycogen;
2. Zimalepheretsa kaphatikizidwe ka shuga pamtengo wama protein;
3. Amachepetsa kuyamwa kwa shuga ndi matumbo a matumbo;
4. Amachepetsa kukana kwa insulini ndikulimbikitsa kukhudzidwa kwa receptor;
5. Imathandizira kusintha kwa mamolekyulu a shuga kukhala lactate m'mimba;
6. Zimasintha kapangidwe ka magazi: zimawonjezera kuchuluka kwa cholesterol ya HDL ("yabwino"), kumachepetsa kuchuluka kwa cholesterol, kumachepetsa triglycerol ndi LDL ("yoyipa" cholesterol);
7. Imathandizira kayendedwe ka glucose kumisempha ya minofu, potero imakulitsa kumwa kwake ndi minofu.

Metforminum: Zizindikiro zogwiritsidwa ntchito

Chinsinsi cha kukalamba ndi kuchuluka kwa glycemia. Mapuloteni amawerengedwa, makwinya mawonekedwe pakhungu, ming'alu imawoneka m'matumbo, momwe mafutawo amapanga zolembera; ma mamolekyulu awiri amafuta amapangidwa kuchokera ku molekyulu imodzi ya shuga.

Koma zotumphukira za metformin sikuti ndim mankhwala ochepetsa shuga okha. Mankhwala ndiwofunikira kwambiri pakakhala vuto la kulolera kwa glucose komanso glycemia wofulumira.

Kuphatikiza pa izi:

• Metformin amasonyezedwa kunenepa kwambiri mu odwala matenda ashuga, ngati ndiwachiwiri, amakwiya chifukwa cha insulin;
• Ntchito kupuma kwa metabolic syndrome;
• Gwiritsani ntchito metformin ya polycystic ovary;
• Gwiritsani ntchito kupewa kupewa kukalamba;
• Zovomerezeka pakuwumba thupi pomanga thupi.

Pamodzi ndi matenda a glycemia, njira zambiri zaukalamba zimachepetsa - kukulira kwa atherosulinosis, kuthamanga kwa magazi kumatulutsa, ndipo mapuloteni osadziwika amakhala olimba. Mlingo wa metformin kuti ukhale ndi moyo nthawi yayitali mpaka 250 mg / tsiku.
Metformin lero sikuti ndi mtundu wokhawo wa shuga: sagwiritsidwa ntchito ndi ma endocrinologists okha, komanso akatswiri azachipatala, akatswiri a zamankhwala, oncologists, ndi ma gynecologists.

Canadian Diabetes Association imalimbikitsa kugwiritsa ntchito Metformin pochiza odwala omwe ali ndi vuto la mtima.

Contraindication pakugwiritsa ntchito mankhwalawa

Mwa mankhwala opangidwa ndi antidiabetes, Metformin ndiye otetezeka kwambiri, wotsutsana kwambiri, kupatula kulephera kwambiri kwa impso.

Metformin sinalembedwe:

• Pa nthawi yoyembekezera komanso yoyamwitsa (mankhwala a insulin amalimbikitsidwa);
• Pogwira opaleshoni yayikulu, maphunziro a radiopaque, kuvulala kwambiri kapena kuwotcha, wodwalayo amasamutsidwa kwa insulin masiku awiri;
• Ngati mbiri ya kukanika kwa chiwindi;
• Ana ochepera zaka 10 - palibe chodalirika pakuchita bwino komanso chitetezo;
• Ndi njala (mpaka 1000 Kcal / tsiku.) Zakudya - acidization wa thupi kumabweretsa metabolic ketoacidosis;
• Mu aimpso a impso, pomwe ma metabolinine amapitilira 0.132 ndi 0,123 mmol / l mwa odwala amuna ndi akazi, motero;
• Ngati wodwala matenda ashuga ali pachiwopsezo cha moyo ndikuyambitsa lactic acidosis.

Chotsutsana chomaliza chinali ma biagunids a m'badwo woyamba ndi wachiwiri.

Izi zotsatirazi zimathandizira kuti pakhale kuchuluka kwa lactic acid komwe kumayambitsa lactic acidosis:

• Kuchepa kwa impso, komwe sikuloleza kuchotsa asidi munthawi yake komanso mwanjira yachilengedwe;
• Kuledzera kwa nthawi yayitali komanso kuledzera kwa ethanol;
• Matenda omwe amayambitsa kupuma movutikira mu minofu (kulephera kwa mtima, matenda amtundu wa kupuma,
• Pachimake m`mnyewa wamtima infarction, zopinga zotupa zam'mapapo mwanga;
• Ketoacidosis (mawonekedwe a matenda ashuga);
• Matenda opatsirana pachimake, limodzi ndi madzi am'mimba chifukwa cha kusanza, kutsegula m'mimba, kutentha thupi.

Nthawi zonse, mankhwalawa amachotsedwa, nthawi zina amakhala osakhalitsa, mpaka homeostasis yathupi ikabwezeretsedwa.

Zotsatira zoyipa

Mankhwala onse opanga alibe zabwino zokha, komanso zovuta, ndipo metformin ndiyosiyana ndi izi. Zotsatira zoyipa kwambiri ndizokhumudwitsa m'mimba.

Oposa 20% ya odwala matenda ashuga omwe akutenga Metformin ali ndi zodandaula:

1. Chifukwa cha zovuta za dyspeptic;
2. Kusokonezeka kwa kayendedwe ka matumbo;
3. Kuchepetsa chilala;
4. Sinthani mumakomedwe (ndimakina achitsulo).

Poyerekeza ndi metformin poyerekeza ndi anthu odwala matenda ashuga, nthawi zambiri zinthu ngati izi zimawonekera poyambira chithandizo ndipo zimatha mosakhalitsa. Izi zitha kufotokozedwa popewa kulowetsa shuga m'makoma a matumbo ang'ono; chifukwa, kupsa ndi mpweya kumawonedwa. Zotsatira zake, izi zimachitika mutamwa mankhwalawa, ndipo m'mimba mumatupa. Pakupita milungu ingapo, matumbo adzazolowera ndipo adzakhazikika.

Ngati matenda am'mimba atatha kumwa mankhwalawa amadzetsa chisangalalo chachikulu, mankhwalawo amathetsedwa kwakanthawi kapena kuti mlingo umachepetsedwa. Ngati izi sizili zokwanira ndipo kuphwanya malamulo sikunadutse, mankhwalawo ayenera kusinthidwa. Pongoyambira - analogue ya wopanga wina.

Malinga ndi ndemanga ya anthu odwala matenda ashuga, metformin, mankhwala oyamba omwe ali ndi dzina la malonda Glucofage, ali ndi zovuta zochepa.

Thupi lawo siligwirizana (erythema, totupa, kuyabwa kwa khungu) ndi osowa, koma amafunika mankhwala mwachangu. Zachidziwikire, muyenera kukumbukira nthawi zonse za lactic acidosis, chifukwa mu 50% ya milandu imeneyi imabweretsa imfa.

Metformin: malangizo ogwiritsira ntchito

Mankhwalawa amalembedwa pamlingo wa prediabetes, komanso monga kupewa patatha zaka 45. Awa ndiwo mankhwala okhawo omwe ali abwino kwa odwala matenda ashuga omwe ali ndi mtundu wachiwiri wamatenda oyambira monotherapy. Kuyambitsidwa panthawi yake ndi chitsimikizo cha kuchita bwino.

Mu Metformin, mawonekedwe a kumasulidwa ndi mitundu iwiri ya mapiritsi: mtundu wautali komanso wachilendo. Amasiyana pakukhudzana ndi nthawi komanso mlingo.

1. Kukonzekera koyenera kungagulidwe pamapiritsi a 500 mg, 850 mg ndi 1000 mg.
2. Ndi mphamvu zokulira - 500 mg ndi 750 mg.

Kumayambiriro kwa maphunzirowa, mlingo wocheperako umasankhidwa - 500 mg / tsiku. Muyenera kugwiritsa ntchito piritsi mosamalitsa ndi chakudya kapena pambuyo pake. Pambuyo pa masabata 1-2, mlingo umasinthidwa ngati kusintha kwa moyo ndi kumwa poyambira sizikuwonetsa zotsatira zomwe mukufuna. Kwa Metformin, mlingo waukulu wa tsiku ndi tsiku ndi 2000 mg / tsiku. Ngati mumamwa mapiritsi musanadye, mphamvu zake zimachepa kwambiri.

Ndikofunikira kumvetsetsa kuti popanda kutsatira mfundo za zakudya zamafuta ochepa komanso kuchita masewera olimbitsa thupi mokwanira, mphamvu ya Metformin imachepetsedwa kwambiri.

Metformin imaphatikizidwa bwino bwino ndi magulu onse a mankhwala antidiabetes, kuphatikiza insulin, ndipo amagwiritsidwa ntchito kawirikawiri pochita zovuta ndi DPP-4 inhibitors, sulfonylureas, thiazolidinediones, b-glucoosidase inhibitors. Kuthekera kwa mankhwalawa sikuwoneka mwachangu: ndikofunikira kuyesa mphamvu ya glycemia palibe kale kuposa masabata awiri atatha kumwa kwa Metformin.

Ndikofunikira kuyang'ana shuga anu ndi glucometer yonyamula m'mawa (musanadye chakudya cham'mawa), maola awiri mutatha kudya komanso musanagone. Ndikofunika kuwongolera kuti zopangika pakati pa zokhwasula sizipitirira maola 4-5. Ngati zisonyezo za glycemic zomwe sizikuyendetsedwa sizikufikireni panthawi yomwe yaperekedwa, muyezo ungasinthidwe mu gawo lovomerezeka.

Kutalika kwa mankhwala

Matenda a shuga ndi njira yamoyo wonse, ndipo ndizosatheka kudziwa kuti maphunzirowa atenga nthawi yayitali bwanji. Zonse zimatengera umboni komanso cholinga chomwe mukufuna. Ngati cholingacho ndichakanthawi kochepa, mwachitsanzo, kuchepa thupi, ndiye kuti mankhwalawo amachotsedwa atangopeza zotsatira zomwe mukufuna.

Mu chithunzichi - zitsanzo zamankhwala pakuwerengera kuchuluka kwa chithandizo cha mankhwalawa ndi metformin (Chinsinsi cha Latin - Rp Tab. Metformini).

Kuthandiza ndi bongo

Mlingo wa hypoglycemia mwangozi kapena mwadala suwopsezedwa, ndipo lactic acidosis ndiyotheka. Vuto loopsa limatha kupha ngakhale mutalandira chithandizo chanthawi yake. Vutoli limatha kuchitika chifukwa cha zovuta zomwe zimayambitsa hypoglycemia.

Lactic acidosis imatha kuzindikiridwa ndi zizindikiro zotsatirazi:

• Kupweteka kwa epigastric;
• Myalgia;
• Matenda a Dyspeptic;
• Kufupika;
• Kugwirizana kwamisala;
• Kutsegula m'mimba
• Kuchepetsa kutentha kwa thupi;
• Kukhumudwitsa.

Ngati chithandizo sichikuperekedwa panthawi, wovutikayo amagwa kukomoka ndipo amatha kufa kwachilengedwe.

Momwe mungathandizire wozunzidwa ndi lactic acidosis? Kuchotsa mankhwala mwachangu ndi kuchipatala. M'mbuyomu, adayesa kuti athetse vuto la kulowetsedwa kwa sodium bicarbonate, koma panali zovuta kuchokera pa sopo. Tsopano chithandizo chotere sichimagwiritsidwa ntchito.

Kodi ndizotheka kusintha mankhwalawo

Ngati wodwala ali ndi contraindication kapena mankhwalawo sioyenera pazifukwa zina, ndikofunikira kusankha kwina.Ngati tsankho siliri lalikulu, mutha kumwa mankhwalawo motengera metformin, koma kuchokera kwa wopanga wina (mwachidziwikire, woyambayo). Kupatula apo, matupi awo sagwirizana sangayambitse zosakaniza zazikulu zokha, komanso ma filler. Ndipo wopanga aliyense amakhala ndi wake.

Ngati metformin imatsutsana pang'onopang'ono, kusinthaku sikungathetse vutoli, chifukwa mndandanda wa zotsutsana ndi izi sizimasintha.

Mankhwala a antidiabetic ali ndi njira yofananira yochitira Metformin:

1. DPP-4 zoletsa za mtundu wa Januvia, Onglisa, Galvus, Trazhenty;
2. Analogs a GPP-4 mtundu Bajeta ndi Victoza;
3. Thiazolidinediones a mtundu Avandia ndi Aktos.

Zomwe zimaperekedwa kuti zidziwike pokhapokha, dokotala ayenera kusankha algorithm yatsopano.

Pamene Metformin Sikuthandizira

Pamabwalo azisangalalo, ena odwala matenda ashuga amadandaula za kusathandiza kwa mankhwalawa. Kodi ndichifukwa ninji mankhwalawa opweteka kwambiri si aliyense 100% angalipire glycemia?

• Ngati mankhwalawo sanatchulidwe malinga ndi mawonekedwe, simungathe kudalira kuti azigwira ntchito bwanji;
• Mlingo wowerengeka molakwika;
• Kuphwanya dongosolo la kumwa mankhwalawa;
• Kulephera kutsatira mfundo za zakudya zamafuta ochepa;
• Kulephera kuchita zolimbitsa thupi;
• Munthu aliyense;
• Zojambula zamagetsi zabwino.

Mukasanthula nkhaniyi ndikuwongolera zolakwikazo, zotsatira zake zimawonekera mofulumira.

Metformin pomanga thupi

Kwa odwala matenda ashuga, mankhwalawa ndiofunikira, amabwezeretsa kagayidwe ka lipid komwe kali ndi matenda. Ikagwiritsidwa ntchito mosalekeza, imatetezanso mitsempha ya magazi kuchokera ku shuga, kuchokera ku cholesterol yowonjezera ndi kuchepa kwamafuta. Koma thupi la othamanga lili ndi mitundu iwiri yosiyanasiyana yokhudza kusintha thupi, ndipo pouma mankhwalawo amagwiritsidwa ntchito mosiyanasiyana.

Ngati mukupita kukalandira mankhwala popanda mankhwala enaake, ndizovuta kuyendera pamalowo: m'malo mwa Metformin, mudzapatsidwa Metfogamma, Bagomet, Siofor, Novoformin, Glyukofazh, Diaformin, Orabet, ... Mankhwala onsewa ali ndi chinthu chimodzi chogwira - Metformin. Mlingo, monga nthawi ya zochitika, ndi osiyana. Yoyenera kusankha? Chachikulu ndikuyimilira pachinthu chimodzi ndikuchigwiritsa ntchito mpaka kumapeto kwa maphunzirowo.

Metformin imathandizira kuchuluka kwa shuga poletsa chakudya m'magawo am'mimba ndikulepheretsa kupanga glycogen m'chiwindi. Thupi limakhala loperewera mphamvu ndipo limayenera kugwiritsa ntchito mafuta ake omwe. Mofananamo, mankhwalawa samabweretsa thupi ku hypoglycemia, chifukwa chake, ngakhale pakudya, othamanga sakhala ndi vuto losafuna kudya.

Mankhwalawo pawokha samawotcha mafuta, koma mafuta ochulukirapo amachoka. Ichi ndi chifukwa cha kukhoza kwa mankhwalawa kuti muchepetse kukana kwa insulini - woyang'anira wamkulu wa kagayidwe kachakudya, wowongolera njala komanso njira yopangira mafuta. Ndipo mafuta ochepera amayikidwa, ocheperako nthawi zambiri amakhala ndi chidwi chokhala pansi ndipo mafuta osungunuka amasungunuka kwambiri.

Aliyense amene amagwiritsa ntchito Metformin kuti achepetse thupi, muyenera kutsatira malamulo kuti mupewe zovuta zowopsa. Mlingo umodzi (500 - 850 mg) umadyedwa ndi chakudya kapena pambuyo awiri kapena katatu patsiku, kumene - mpaka miyezi itatu. Ndikofunikira kuchepetsa zakudya zamagulu a shuga komanso zakudya zamafuta othamanga kuti musakhale ndi zotsatirapo za kukhumudwitsa m'matumbo. Kuchuluka kwa madzimadzi oledzera kumayenera kukhala 30 ml pa 1 kg ya kulemera. Tiyenera kudziwa kuti

Kumayambiriro kwa maphunzirowa, othamanga amakhala ndi zizindikiro zofanana ndi toxosis ya amayi apakati: nseru, kuchepa kwa chakudya, kusintha kwa kukoma komwe kumadza chifukwa chosowa chakudya. Kusakhudzika kumadutsa pakokha kapena pambuyo pa kusintha kwa mlingo. Ndikofunika kuti tisafe ndi njala! Ndi matenda a chiwindi ndi impso, ndibwino kuti musayesere kuwonda.

Mndandanda wathunthu wa contraindication wa Metformin uli mu malangizo a boma kuti mugwiritse ntchito. Simungamwe zakumwa zowonjezera mothandizidwa ndi diuretiki kapena mankhwala ofewetsa tuvi tofanana ndi izo - chiwopsezo cha kuvulaza impso ukuwonjezeka.

Werengani zambiri za kugwiritsidwa ntchito kwa Metformin pamasewera - pa masewera ndi chidziwitso pa SPORT SCIENCE

Kodi ndikofunika kuchepetsa thupi ndi metformin

Pofunafuna chithunzi choyenera, chomwe sitigwiritsa ntchito, ngakhale njirayo ikukayikira, ndipo mapiritsi nthawi zambiri amavulaza thanzi. Ndikofunika kukumbukira kuti Metformin poyambirira adapangidwa kuti azilamulira matenda a shuga a 2. Pophunzira maluso ake, zidapezeka kuti zimapangitsa kunenepa kwambiri - chimodzi mwazifukwa zazikulu zoyambitsa matenda opatsirana.

Kodi mankhwalawa amagwira ntchito bwanji ndipo kunenepa kwambiri nthawi zonse kumayenderana ndi kudya kwambiri? Madokotala amatsimikizira kuti mu 99% ya milandu, anthu onenepa amakula insulin. Ntchito ya insulin ndikutsatira glucose m'maselo. Mu kapisozi wamafuta m'maselo, chidwi chake chimachepa, ndipo mamolekyule "okoma" samalowa. Zotsatira zake, kapamba amalandila chizindikiro kuchokera ku b-cell kuti tifulumizitse kaphatikizidwe ka insulin, ndi mitundu yake yowonjezera m'magazi. Izi zimabweretsa vuto la lipid metabolism, popeza tsopano ndizosavuta kuphatikiza mafuta.

Pali zifukwa zambiri zomwe zimapangitsa chidwi cha maselo kulowa insulini kuchepa, koma chachikulu ndicho kudya kwambiri mafuta m'thupi. Maselo omwe amakhala ndi glucose amatsekedwa kuchokera ku insulin. Ndipo kuchuluka kwa mahomoni akuchuluka m'thupi, kumakhala kosavuta kwa iye. Zotsatira za kuzungulira koipa kumeneku kumakhala kunenepa kwambiri, kukana insulini komanso hyperinsulinism.

Mankhwalawa amabwezeretsa chidwi cham'magazi ndikubwezeretsanso mahomoni. Glucose nthawi zambiri imalowa, insulin imapangidwa nthawi zambiri, sizithandiza kuti pakhale mafuta.

Mankhwala ali ndi osachulukira concomitant zotsatira - anorexigenic. Ndizomwe aliyense amafunikira akagula mankhwala ndi cholinga chongofuna kuchepetsa thupi. Koma mankhwalawa amachepetsa kudya pang'ono ndipo samathandiza aliyense.

Malangizo ochepetsa thupi pa Metformin

Palibe piritsi yamatsenga yomwe imawotcha mafuta mwachangu pomwe mukumangiriza bun ina pa TV.

Mwakutero, mutha kuchepetsa thupi popanda Metformin, popeza kutsimikizika kwakukulu ndikadali ndi moyo wathanzi. Chenjezo ili silikugwira ntchito kwa odwala matenda ashuga omwe ali ndi kunenepa kwambiri. Koma ngati atsikana athanzi amakhala omasuka kuchepetsa thupi ndi mapiritsi, muyenera kuchita molondola.

Mutha kugula analog iliyonse ya Metformin, kampani iliyonse yamankhwala imapangira pansi pa dzina lake kapena kuwonjezera pa choyambirira: Teva, Canon, Richter. Makapisozi amasiyana mu kapangidwe ka zigobazi komanso mafilimu. Nthawi zambiri zimayambitsa zovuta zilizonse, ngakhale mankhwalawo ali ndi zolakwika zake zomwe zimakhudzana ndi zotsatira zoyipa, zomwe zimayenera kudziwa kuchepa kwa thupi.

Yambitsani maphunzirowa ndi osachepera 500 mg, kumwa mapiritsi kamodzi. Mankhwalawa amapangidwa mosiyanasiyana. Ngati mumayamba ndi Mlingo wina, mutha kumva kuyambira masiku oyamba onse osangalala ndi zotsatira zoyipa, makamaka m'mimba. Mlingo wapamwamba ndi 3000 mg / tsiku, koma madokotala ambiri amalimbikitsa kuti azikhala ndi 2000 mg / tsiku.

Mankhwalawa amadyedwa pakudya kapena mutatha kudya. Mutha kutenga usiku, chiwembu choterechi ndikulangizidwanso.
Ngati kuyambira m'masiku oyamba zotsatira zoyipa zikuwonekera ndipo thupi silinazolowere kwa masiku 14 a kudya pafupipafupi, mankhwalawo amafunikira.

Maganizo a kunenepa

About Metformin, ndemanga yochepetsera thupi, makamaka, siyabwino. Omwe adakwaniritsa zotsatira zomwe amafunikira sanagwiritse ntchito mankhwalawa komanso njira zina, chifukwa chake ndizovuta kupereka lingaliro la munthu.

Metformin: ndemanga za madokotala

Mwachidziwikire, Metformin siwowonjezera zakudya zatsopano kapena wowotcha mafuta, koma mankhwala owopsa omwe ali ndi umboni wamphamvu wazotsimikizira, ngati atengedwa pazolinga zake. Zotsatira zamankhwala

Mutha kuphunzira metformin kuchokera pa kanemayo