Isofan insulin (wopangidwa mwamajini)

Ndi matenda a shuga, posachedwa, kuchepa kwa insulin yopangidwa ndi kapamba kumayamba kumveka, kuchepa kwake kumapangidwa ndi yankho la mahomoni opanga, omwe amabailidwa.

Isofan insulin ndi imodzi mwazinthu zomwe zimathandizira kuchiritsa. Mu thupi, insulin iyi imakhala ngati yachilengedwe: imatumiza glucose ochulukirapo ku minofu, komwe imasweka, ndikupatsa thupi mphamvu. Ndi matenda a shuga amtundu woyamba, Isofan nthawi zonse amaphatikizidwa ndi mahomoni ofupikirako, omwe amapangidwira kuti azilamulira pambuyo pakudya (pambuyo pa kudya) glycemia. Mtundu 2, matenda a insulin Isofan okha ndi omwe angakwanitse odwala matenda ashuga.

The zikuchokera mankhwala

Insulin yomwe imagwiritsidwa ntchito mu shuga imagawidwa m'magulu akulu akulu kutengera nthawi yomwe akuchitapo kanthu. Kuti mutsanzire kwathunthu kutetezedwa kwanu kwa insulin, mumafunikira timadzi tambiri tating'onoting'ono. Isofan imatchulidwa ngati insulin yapakati. Pogwiritsa ntchito magawo awiri patsiku, imatha kupereka kuchuluka kwa mahomoni m'magazi, omwe amachepetsa glucose, omwe amalowa m'magazi kuchokera pachiwindi kuzungulira nthawi.

Isofan insulini ilipo 2:

1. Insulin. M'mbuyomu, mahomoni a nkhumba ndi bovine anali ogwiritsidwa ntchito, tsopano ndi maumboni amtundu wa anthu omwe amagwiritsidwa ntchito okha, omwe ali ofanana ndi mahomoni opangidwa ndi kapamba amunthu. Amapangidwa pogwiritsa ntchito mabakiteriya osinthika, mankhwalawa amakhala ndi kuyeretsa kambiri, amadziwika mosavuta ndi thupi ndipo sakonda kuyambitsa ziwengo kusiyana ndi omwe adalipo kale.
2. Protamine - mapuloteni omwe amagwiritsidwa ntchito ngati ntchito yowonjezera insulin. Tithokoze iye, nthawi ya kudya kwa mahomoni kuchokera ku minofu yolowerera m'matumbo imachulukitsa kuyambira maola 6 mpaka 12. Mu insulin, Isofan hormone ndi protamine zimasakanizidwa mu kuchuluka kwa isophane, ndiye kuti, palibe zochulukirapo pazinthu zilizonse zomwe zikuyankhidwa. Mwa dzina la mlengi wake, wasayansi waku Danish Hagedorn, insulin Isofan imakonda kutchulidwa m'mabuku azachipatala kuti ndi protamine Hagedorn, kapena NPH-insulin.

Kotero kuti protamine yokhala ndi insulin imatha kupanga makhiristo, zinc imawonjezeredwa ku yankho. Phenol ndi m-cresol amapezeka pokonzekera ngati zosungirako; kuti mupeze yankho ndi kusakhazikika kwa acidity, asidi wofowoka kapena maziko amagwiritsidwa ntchito. Kwa fanizo la mitundu yosiyanasiyana, kapangidwe kazinthu zothandizira ndi kosiyana, mndandanda wathunthu umaperekedwa mu malangizo ogwiritsira ntchito.

Matenda a shuga ndi kupsinjika kudzakhala chinthu chakale

• Matenda a shuga -95%
• Kuthetsa kwa mitsempha thrombosis - 70%
• Kuthetsa kwa kugunda kwamtima kwamphamvu -90%
• Kuthana ndi kuthamanga kwa magazi - 92%
• Kuwonjezeka kwa mphamvu masana, kukonza kugona usiku -97%

Zisonyezero zakudikirira

Chifukwa choika basulin yokumba insulin:

1. Mtundu umodzi wa matenda ashuga. Makina olimbitsa a insulini amagwiritsidwa ntchito, ndiye kuti onse a ISofan ndi insulin yochepa amagwiritsidwa ntchito.
2. Mitundu ina ya matenda a shuga a Mody.
3. Lembani 2, ngati mapiritsi a hypoglycemic adatsutsana kapena samapereka chiwongolero chokwanira cha matenda ashuga. Monga lamulo, mankhwala a insulin amayamba ndi Isofan. Kufunika kwa mahomoni ofupikira kumawonekera pambuyo pake.
4. Lembani 2 pakubala.
5. Monga m'malo mwa mapiritsi, ngati mtundu wachiwiri wa matenda a shuga uli pachiwopsezo. Pambuyo pakuchepetsa shuga, wodwalayo amatha kusamutsidwanso kukonzekera kukamwa.
6. Matenda a shuga, ngati chakudya chapadera sichimachepetsa shuga kukhala yabwinobwino.

Zizindikiro

Isofan Insulin ndiye insulin wotchuka kwambiri padziko lapansi. Mankhwala amakono owonjezereka ndi okwera mtengo kwambiri ndipo ayamba kugulitsa msika. Mayina amalonda otsatirawa a Isofan amalembetsedwa ku Russian Federation:

Mankhwala onse omwe ali pamwambapa ndi ma analogu. Amakhala ndi nkhawa yofananira ndipo ali pafupi ndi mphamvu, chifukwa chake, ndi matenda ashuga, ndizotheka kusintha kuchokera ku mankhwala amtundu wina kupita kwina popanda kusintha kwa mlingo.

Mfundo yogwira ntchito

Isofan insulin ili ndi hypoglycemic effect. Pang'onopang'ono timadzipangitsa kulowa m'magazi tomwe timatulutsa ma cell a cell. Chifukwa cha izi, nembanemba limakhala lololeka kwa glucose, ndipo imatha kulowa mu cell, pomwe imawola ndi kutulutsa mphamvu. Mwazi wamagazi, motero, umachepa.

Insulin imathandizanso kupanga glycogen mu minofu ndi chiwindi, yomwe imapangidwa kuchokera ku glucose ndipo ndi mtundu wamphamvu zopulumutsa thupi. Malo osungirako akagwiritsidwa ntchito ngati shuga m'magazi amakhala otsika.

Chochita china chofunikira cha insulin ndikupewa kuwonongeka ndi kusokonekera kwa mapuloteni ndi chakudya chamagulu.

Kutalika kwa jakisoni imodzi ndizosiyana kwambiri mwa anthu osiyanasiyana. Zimatengera malo komanso kuya kwa jakisoni, kuchuluka kwa magazi kumalo amtunduwu, mlingo, mtundu wa matenda osokoneza bongo, kutentha kwa thupi ndi zina.

Mbiri ya ntchito ya Isofan insulin, yowerengeka pa malangizo ogwiritsira ntchito:

Imaphwanya insulin ndi ma enzymes apadera, pomwe metabolites imapangidwa, yopanda shuga yotsitsa. Kutha kwa theka la moyo kumasiyana mkati mwa maola 5-10.

Zotsatira zoyipa za Isofan Insulin

Zotsatira za insulin zimakhudzidwa kwambiri ndi zinthu zachilengedwe. Ngati insulin yambiri ilowa m'malo momwe thupi limafunikira, odwala matendawa amakhala ndi hypoglycemia. Amatha kutsogolera ku izi:

1. Kusala, kudumpha zakudya - onani nkhani yokhudza kusala kudya shuga.
2. Zakudya zam'mimba zomwe zimalepheretsa kuyamwa kwa shuga: kusanza, kutsegula m'mimba.
3. Kuchita zolimbitsa thupi mosalekeza.
4. Zowonjezera ndi mapiritsi a antidiabetes.
5. Matenda a Endocrine.
6. Matenda akulu a ziwalo zomwe zimagwira mu metabolism ya insulin: chiwindi ndi impso.
7. Kusintha tsamba la jakisoni, thupi (kupukusa, kutikita minofu) kapena kutentha (sauna, Kutentha pad) kumabweretsa zotsatira zake.
8. Njira yolakwika ya jakisoni.
9. Mapiritsi omwe amalimbikitsa mphamvu ya insulin. Mankhwala a Hormonal ndi diuretic amakhala ndi zotsatira zabwino kwambiri.
10. Mowa ndi chikonga.

Ndi shuga dontho ladzidzidzi la shuga, onse odwala matenda ashuga omwe amagwiritsa ntchito insulin amayamba. Zimaphatikizanso kudya kwa chakudya chama carbohydrate othamanga, pamavuto akulu - jakisoni wa 1 mg wa glucagon, dontho lokhala ndi glucose - zambiri zomwe mungachite ngati shuga ya magazi igwera kwambiri.

Pafupipafupi, odwala matenda a shuga a m'mellitus amakumana ndi lipodystrophy (kusintha kwa dystrophic m'mafuta opindika pafupipafupi m'malo opezeka jekeseni) ndi hypersensitivity reaction mu mawonekedwe a edema, totupa, komanso redness.

Malamulo oyambira

Mlingo wa Isofan umasankhidwa choyamba, kufupikitsa insulin. Ndi payekha payekhapayekha wodwala matenda ashuga. Pafupifupi kufunika kwathunthu kwa mahomoni posakhalapo ndi magawo 0,3-1 pa 1 kg yolemera, Isofan imakhala ndi 1/3 mpaka 1/2 ya kufunika. Insulin yocheperako imafunikira mtundu wa matenda a shuga 2, makamaka - kwa odwala omwe ali ndi kunenepa kwambiri komanso kukana insulin. Zolemba muzakudya sizikhudza kwenikweni mtundu wa Isofan, chifukwa insulin yochepa imathandizira kulipirira prandial glycemia.

Momwe mungasinthire Isofan:

1. Malangizowo akuwongolera kuperekera mankhwalawo pang'onopang'ono. Pofuna kuti vutoli lisalowe mu minofu, muyenera kusankha kutalika kwa singano yoyenera. Kuwongolera kwapakati ndi koletsedwa.
2. Kwa makina, ma insulin ma insulin ndi zolembera zamakono kwambiri za syringe zingagwiritsidwe ntchito. Insulin yapakatikati singagwiritsidwe ntchito pamapampu.
3. Isofan insulin ndi kuyimitsidwa, kotero kutengeka kumapangika pakapita nthawi kumapeto kwa vial. Musanapange jakisoni, mankhwalawa amayenera kusakanizika bwino. Ngati sizotheka kukwaniritsa utoto wofanana ndi kuyimitsidwa, insulin imasowa, ndipo singagwiritsidwe ntchito.
4. Tsamba labwino kwambiri la jekeseni ndi ntchafu. Amaloledwanso kuti apange jakisoni m'mimba, matako, phewa - momwe angabayire insulin molondola.
5. Pangani jekeseni yatsopano osachepera 2 cm kuchokera kumbuyomu. Mutha kubaya pamalo omwewo pakatha masiku atatu.

Kugwiritsa Ntchito Mimba

Isofan imatha kugwiritsidwa ntchito pa nthawi yoyembekezera komanso HB, chifukwa sizilowa m'magazi a mwana kudzera mu placenta komanso mkaka. Mwa amayi omwe ali ndi matenda ashuga omwe ali ndi mwana, mankhwala a insulin ndiye njira yokhayo yochepetsera glycemia yomwe imaloledwa ku Russia.

Kufunika kwa mankhwalawa kwa miyezi 9 kumasintha mobwerezabwereza nthawi yomweyo ndi kusintha kwa mayendedwe mahomoni a mkazi, kotero muyenera kusinthitsa kawirikawiri mlingo wa insulin. Kuwongolera kwambiri shuga panthawi yoyembekezera ndi njira yofunikira yothandizira kupewera kwa fetupathy, kusokonezeka, kufa kwa fetal.