Glucobai a mtundu 2 wa shuga komanso kuwonda

Glucobai ndiwowongolera padera pa tsiku lililonse la glycemia. Imagwira machenjezo: samachotsa shuga m'magazi, ngati mapiritsi ena a antidiabetes, koma amaletsa kulowa kwake mu ziwiya zam'mimba zawo. Mankhwalawa ndi okwera mtengo komanso osagwira ntchito kuposa metformin kapena glibenclamide, ndipo nthawi zambiri amadzetsa mavuto m'mimba.

Ambiri a endocrinologists amaganiza kuti Glucobai ndi mankhwala osungira. Amatchulidwa pamene wodwala matenda ashuga ali ndi contraindication chifukwa chomwa mankhwala ena kapena kuphatikiza nawo kuti apititse patsogolo hypoglycemic. Glucobai imadziwikanso bwino pamagulu ozungulira akufuna kuchepa thupi ngati njira yochepetsera zakudya zopatsa mphamvu.

Zikuyenda bwanji Glucobay

Zomwe zimagwira mu Glucobay ndi acarbose. M'matumbo ang'onoang'ono, acarbose imakhala mpikisano wa saccharides, omwe amabwera ndi chakudya. Imachedwetsa, kapena imalepheretsa, ma alpha-glucosidases, ma enzymes apadera omwe amaphwanya zakudya zamagetsi kukhala monosaccharides. Chifukwa cha izi, kulowetsa shuga m'magazi kumachedwetsedwa, ndipo kulumpha kwakuthwa mu glycemia mukatha kudya kumaletsedwa mu shuga. Mutatha kumwa mapiritsi, gawo limodzi la glucose limazengereza ndikachedwa, linalo limachotsedwa m'thupi popanda kufinya.

Acarbose m'thupi siliyamwa, koma imaphatikizidwa m'mimba. Oposa theka la acarbose amachotsera ndowe, motero amatha kuthandizidwa ndi nephropathy komanso kulephera kwa chiwindi. Pafupifupi gawo limodzi mwa magawo atatu a metabolites a chinthu ichi amalowa mkodzo.

Malangizo ogwiritsira ntchito amalola kugwiritsa ntchito Glucobay ndi metformin, kukonzekera kwa sulfonylurea, insulin. Mankhwalawo pawokha sangathe kuyambitsa hypoglycemia, koma ngati kuchuluka kwa othandizira a hypoglycemic ndikofunikira kuposa momwe angafunikire, shuga amatha kugwa pansi pazoyenera.

Matenda a shuga ndi kupsinjika kudzakhala chinthu chakale

• Matenda a shuga -95%
• Kuthetsa kwa mitsempha thrombosis - 70%
• Kuthetsa kwa kugunda kwamtima kwamphamvu -90%
• Kuthana ndi kuthamanga kwa magazi - 92%
• Kuwonjezeka kwa mphamvu masana, kukonza kugona usiku -97%

Ndani amasankhidwa mankhwalawo

Glucobay mankhwala ndi mankhwala:

1. Kubwezera mtundu wa matenda ashuga a 2 nthawi imodzi ngati kukonza zakudya. Mankhwalawa sangathe kusintha chakudya chochepa cha carb kwa onse odwala matenda ashuga, chifukwa izi zimafuna mlingo waukulu kwambiri, ndipo pakuwonjezeka kwa mankhwalawo, kuopsa kwa zotsatira zoyipa za Glucobay kumakulanso.
2. Kuthetsa zolakwika zazing'ono mu chakudya.
3. Monga gawo la chithandizo chokwanira ndi mankhwala ena, ngati sataya glycemia.
4. Kuphatikiza pa metformin, ngati odwala matenda ashuga ali ndi kuchuluka kwa insulin komanso sulfonylureas sakusonyezedwa.
5. Ngati mukufuna kuchepetsa kuchuluka kwa insulin mu mtundu 2 wa matenda ashuga. Malinga ndi odwala matenda ashuga, mlingo umatha kuchepetsedwa ndi magawo khumi ndi anayi patsiku.
6. Ngati triglycerides m'magazi ndi apamwamba. Insulin yochulukirapo imaletsa kuchotsedwa kwa lipids m'mitsempha yamagazi. Pochepetsa shuga m'magazi, Glucobai imachotsanso hyperinsulinemia.
7. Kuyamba kwamtsogolo kwa insulin. Anthu odwala matenda ashuga achikulire amakonda kupilira mavuto omwe amapezeka m'mapiritsi poopa jakisoni wa insulin.
8. Mankhwalawa matenda oyamba a carbohydrate metabolism: prediabetes, NTG, metabolic syndrome. Malangizowa akuwonetsa kuti Glucobai wogwiritsidwa ntchito nthawi zonse ndi 25% amachepetsa mwayi wokhala ndi matenda ashuga. Komabe, pali umboni kuti mankhwalawa samakhudza zifukwa zazikulu zoyambitsa kuphwanya: insulini kukaniza ndi kuchuluka kwa kupanga kwa chiwindi ndi chiwindi, chifukwa chake madokotala amakonda kupereka metformin yothandiza kwambiri kupewa matenda a shuga.
9. Kuwongolera thupi. Ndi matenda a shuga, odwala ayenera kulimbana ndi kunenepa kwambiri nthawi zonse. Glucobay imathandizira kukhala ndi thupi labwino, ndipo nthawi zina zimathandizanso kuchepetsa kunenepa.

Kafukufuku akuwonetsa kuti mankhwalawa amagwira bwino kwambiri odwala matenda ashuga okhala ndi shuga wochepa komanso kuwonjezeka kwa postprandial glycemia. Kafukufuku wachipatala awonetsa kuchepa kwa shuga: pamimba yopanda kanthu ndi 10%, mutatha kudya ndi 25% kwa miyezi isanu ndi umodzi ya chithandizo ndi Glucobay. Kutsika kwa hemoglobin wa glycated kunakwana 2,5%.

Malangizo a kumwa mankhwala

Mapiritsi a Glucobai amatha kuledzera nthawi yomweyo musanadye, kutsukidwa ndi madzi pang'ono, kapena kutafuna limodzi ndi supuni yoyamba ya chakudya. Mlingo wa tsiku ndi tsiku umagawika katatu ndipo umamwe ndi zakudya zazikulu. Nthawi zina, mankhwalawa sagwira ntchito. Glucobai ali ndi mitundu 2 ya kusankha: 50 kapena 100 mg ya acarbose piritsi limodzi. Piritsi la 50 mg laledzera kwathunthu, malangizo a Glucobai 100 mg amakulolani kugawa pakati.

Dose Selection Algorithm:

Mlingo wa Glucobai umakulitsidwa ngati chiyambi sichimapereka shuga. Popewa zoyipa, onjezani mapiritsi pang'onopang'ono. Miyezi 1-2 iyenera kudutsa pakati pa kusintha kwa mlingo. Ndi prediabetes, mlingo woyambira umagwira bwino pakadutsa miyezi itatu. Malinga ndi ndemanga, zomwezo zimagwiritsidwa ntchito pakuchepetsa thupi monga Chithandizo cha prediabetes.

Mtengo wa paketi ya mapiritsi 30 Glucobai 50 mg - pafupifupi ma ruble 550., Glucobai 100 mg - 750 rubles. Mukamamwa mlingo wambiri, chithandizo chidzafunika ma ruble 2250. pamwezi.

Zotsatira zoyipa zingakhale ndi

Pa maphunziro azachipatala a Glucobay, zotsatirazi zoyipa adazindikiridwa ndikuwonetsa mu malangizo (omwe adapangidwa mwatsatanetsatane wa pafupipafupi):

1. Nthawi zambiri - kuchuluka kwa mpweya m'matumbo.
2. Nthawi zambiri - kupweteka kwam'mimba chifukwa cha kuchuluka kwa mpweya, kutsegula m'mimba.
3. Nthawi zambiri - kuwonjezeka kwa michere ya chiwindi, mukamatenga Glucobay imatha kukhala yochepa ndikutha pakokha.
4. Pafupipafupi, kuchepa kwa michere yam'mimba, nseru, kusanza, kutupa, jaundice.

Mu nthawi yotsatsa itatha, zidziwitso zidapezeka pazomwe zimapangitsa kuti pakhale magawo a mapiritsi a Glucobay, matumbo a kutupa, hepatitis, thrombocytopenia. Acarbose imachepetsa pang'ono mkaka wa m`mawere, womwe umafunika kuti mkaka uwonongeke, kotero mukamwa mankhwala, tsankho la mkaka lonse limatha.

Pafupipafupi komanso kuopsa kwa zovuta za mankhwalawa zimatengera mlingo wake. Zotsatira zoyipa zikachitika, kusiya mankhwala sikofunikira nthawi zonse, nthawi zambiri kumachepetsa.

Kugwiritsa ntchito Glucobay kumachepetsa kwambiri zotsatira zoyipa monga kusanja. Pafupifupi palibe amene zinthu zimamuyendera bwino popewa izi, popeza momwe zimagwirira ntchito zomwe mankhwalawo amathandizira pakupanga mpweya. Kuthira mafuta osaphatikizika kumayambira m'matumbo, komwe kumayendera limodzi ndi kutulutsa kwa mpweya. Chifukwa chake, mafuta ochulukirapo omwe amapezeka m'zakudya, njira zowotchera zimakhala zamphamvu. Flatulence imatha kuchepetsedwa pokhapokha kutsatira zakudya zamafuta ochepa.

Kwa odwala matenda ashuga, izi zimatha kuonedwa ngati zabwino. Choyamba, Glucobay amakhala mtundu wowongolera, osalola kuswa chakudya chomwe wapatsidwa. Kachiwiri, odwala matenda ashuga nthawi zambiri amakhala ndi chizolowezi chodzimbidwa, ndipo Glucobai imakulolani kuti musinthe chopondacho popanda kugwiritsa ntchito mankhwala ofewetsa thukuta.

Contraindication

Okhazikika contraindication kutenga Glucobay - hypersensitivity mankhwala, ubwana, HBV ndi pakati. M'matumbo am'mimba, kuwunikira kowonjezereka kumafunikira kuti mudziwe kuchuluka kwa chimbudzi ndi mayamwidwe. Matenda omwe flatulence imawonjezeka amathanso kukhala cholepheretsa kutenga Glucobay. Kulephera kwakukulu kwa aimpso ndi GFR <25, excretion ya acarbose metabolites imasokonekera, ina yomwe imagwira. Kugwiritsa ntchito Glucobay pankhaniyi ndizoletsedwa, chifukwa zimapangitsa kuti pakhale mankhwala ochulukirapo.

Glucobay yochepetsa thupi

Malangizo ogwiritsira ntchito alibe zambiri zomwe Glucobai amathandizira kuti achepetse thupi, ndiye kuti, izi zomwe mankhwalawo sanatsimikizire sizovomerezeka. Komabe, pali maphunziro omwe mapiritsiwa adayerekezedwa ndi zakudya zamafuta ochepa. Zinapezeka kuti mphamvu ya Glucobay yochepetsa thupi imafanana ndi kuchepa kwa zopatsa mphamvu 500-600. Kafukufukuyu adachitika mgulu la anthu omwe ali ndi chiwopsezo chachikulu cha matenda ashuga: kunenepa kwambiri, matenda oopsa, kapena metabolic syndrome. Amaganiziridwa kuti mankhwala a Glucobay, akumachepetsa shuga m'mitsempha yamagazi, nthawi yomweyo amachepetsa kukana kwa insulin, komwe kumawonedwa mwa ambiri mwa odwalawa. Kuchuluka kwa insulin kaphatikizidwe kumangosinthidwa zokha, zomwe zikutanthauza kuti kuchepa thupi kumathandizidwa.

Zotsatira zamafuta osaphatikizika omwe sangathe kuwerengera sizingatheke kuwerengeka, chifukwa kuchuluka kwawo kumasiyana kwambiri kutengera kapangidwe kazinthuzo ndi mawonekedwe a chimbudzi. Malinga ndikuwunika kochepa, gawo lofunikira limaseweredwa ndi zotsatira zoyipa zomwe zimachepetsa kuthana ndi zakudya zamafuta apamwamba kwambiri.

Analogi

Glucobai ndi mankhwala okhawo omwe amalembetsa ku Russia ndi acarbose, alibe maganizidwe athunthu. Kuphatikiza apo, m'masitolo athu ogulitsa simungagule ma analogi a gulu - mankhwala omwe ali ndi gulu lomwelo.

Ma alpha-glucosidase inhibitors atha kugulitsidwa ku pharmacies akunja:

Mwa zofanizira za Glucobay, zotsika mtengo kwambiri ndi Chiyukireniya Voksid, mtengo wake umachokera ku ma ruble 150. pa paketi iliyonse ya mapiritsi 30 kuphatikiza. Pafupifupi mapake atatu atatu amafunikira pamwezi.

Ndemanga Zahudwala