Isofan insulin umisiri wamtundu wa anthu

Mankhwala ndi a sing'anga a nthawi yayitali. M'malo mwake, iyi ndi insulin yaumunthu, yomwe idalandiridwa chifukwa cha ukadaulo wa DNA.

Zotsatira za pharmacological

Isulin insulin imakhala ndi hypoglycemic. Imalumikizana ndi ma receptors apadera pa cell ya cytoplasmic cell membrane ndipo imapanga insulin-receptor system yomwe imalimbikitsa njira zamkati, zomwe zimaphatikizira kaphatikizidwe kamkati mwa michere yofunika (pyruvate kinase, hexokinase, glycogen synthetase).

Kuwonjezeka kwa kutengeka kwanyimbo kwa glucose kumapangitsa kuchepa kwa magazi ake m'magazi. Zimathandizanso kuchepa kwa kuchuluka kwa shuga mu chiwindi, kuchuluka kwa mayamwidwe ndi kuphatikizidwa ndi minofu. Zimapangitsa glycogenogeneis, lipogeneis, kaphatikizidwe kazinthu kena.

Kuchuluka kwa mayamwidwe, chifukwa mankhwalawa amakhala ndi mphamvu yayitali, zimatengera zinthu zingapo nthawi imodzi: malo ndi njira yoyendetsera, mlingo. Pankhaniyi, zochita za insulin zimatha kusintha mpaka pamlingo waukulu. Kuphatikiza apo, kusinthaku kutha kuwonedwa osati mwa anthu osiyanasiyana, komanso mwa wodwala yemweyo.

Pambuyo pokonzanso jakisoni, pafupifupi, mankhwalawa amayamba kugwira ntchito pambuyo pa maola 1.5, ndipo mphamvu yakeyo imapezeka pakadutsa maola 4 mpaka 12. Mphamvu ya mankhwalawa imatha kwa maola 24.

Kukhazikika kwa mavutowo ndi kukwanira kwathunthu kwa insulin kumasiyana:

• kuchokera pa tsamba la jakisoni (pamimba, matako, ntchafu);
• pa kuchuluka kwa timadzi mu mankhwala;
• pa kuchuluka kwa mankhwala a insulin omwe amaperekedwa.

Zina:

1. Sipezeka mkaka wa m'mawere.
2. Momwe zimagawidwira matendawa.
3. Sichikudutsa malire oyimitsa.
4. 30-80% yowonjezera impso.
5. Amawonongedwa ndi insulinase makamaka impso ndi chiwindi.

Kodi kumwa isofan insulin

• Matenda a shuga ndi mtundu II.
• Gawo la kukana hypoglycemic mkamwa mankhwala.
• Pa kuphatikiza chithandizo, kukana pang'ono kwa mankhwala a gulu lino.
• Type II matenda ashuga mwa amayi apakati.
• Matenda apakati.

Contraindication

Hypoglycemia, hypersensitivity, komanso hypoglycemia pa nthawi yapakati.

Zotsatira zoyipa za mankhwala a insulin isofan

Zogwirizana ndi zomwe zimapangitsa kagayidwe kazakudya:

Hypoglycemia:

1. kutulutsa thukuta kophatikizidwa
2. njala
3. kukopa kwa pakhungu
4. kugwedezeka, tachycardia,
5. chisangalalo
6. mutu
7. paresthesia mkamwa;
8. kwambiri hypoglycemia, yomwe imakhala yodzala ndi kukula kwa chikumbumtima cha hypoglycemic.

Mawonekedwe a mziwi wawo ndi osowa kwambiri:

• Edincke's edema,
• zotupa pakhungu
• anaphylactic mantha.

Zina:

• Nthawi zambiri kumayambiriro kwa chithandizo chosakhalitsa zolakwika;
• kutupa.

Zomwe zimachitika:

1. kutupa ndi kuyabwa m'malo a jakisoni;
2. hyperemia;
3. lipodystrophy m'dera la jakisoni (wogwiritsa ntchito nthawi yayitali).

Kuchita

Limbikitsani zotsatira za hypoglycemic:

• Mao zoletsa;
• hypoglycemic mkamwa mankhwala;
• bromocriptine;
• kaboni anhydrase zoletsa;
• sulfonamides;
• fenfluramine;
• kukonzekera kokhala ndi ethanol;
• ACE zoletsa;
• osasankha beta-blockers;
• mebendazole;
• kukonzekera kwa lithiamu;
• tetracyclines;
• ketoconazole;
• anabolic steroids;
• cyclophosphamide;
• octreotide;
• pyridoxine;
• onjezerani;
• theofylline.

Walephera hypoglycemic zotsatira za insulin:

1. thiazide okodzetsa;
2. kulera kwamlomo;
3. diazoxide;
4. mahomoni a chithokomiro;
5. morphine;
6. glucocorticoids;
7. danazole;
8. heparin;
9. BKK;
10. ma tridclic antidepressants;
11. chikonga;
12. sympathomimetics;
13. clonidine;
14. phenytoin.

Koma salicylates ndi reserpine zimatha kufooketsa ndikuwonjezera zochita za insulin.

Bongo

Pankhani ya bongo, hypoglycemia imatha kuchitika.

Hypoglycemia Chithandizo

Wodwala amatha kuthana ndi hypoglycemia pakudya chidutswa cha shuga, maswiti kapena zakudya zopatsa thanzi. Chifukwa chake, odwala matenda ashuga ayenera kukhala ndi shuga, ma cookie, maswiti kapena msuzi wa zipatso limodzi nawo.

Masewera a hypoglycemia, wodwalayo akapanda kuzindikira, 40% ya dextrose kapena glucagon amaphatikizidwa kudzera m'mitsempha.

Insulin yomaliza yopanga ma genulin imatha kuperekedwa kudzera m'mitsemvu yonse komanso m'njira zina. Chikumbumtima chikadzabweranso mwa munthu, amafunika kudya zakudya zamafuta ambiri, izi zimalepheretsa kukonzanso kwa hypoglycemia.

Mlingo ndi makonzedwe

Mlingo wa sc umatsimikiziridwa ndi katswiri aliyense payekhapayekha. Zimakhazikika pamlingo wa glucose m'magazi a wodwala. Wapakati tsiku lililonse mankhwalawa amasiyana 0,5 mpaka 1 IU / kg, zimatengera kuchuluka kwa shuga m'magazi komanso mikhalidwe ya wodwalayo, momwe amathandizira ndi insulin isofan ya anthu komanso jini.

Isofan insulin, ngati munthu komanso mankhwala opangidwa ndi chibadwa, nthawi zambiri amilowetsa mu ntchafu, koma jakisoni amatha kupangira kholingo, khoma lamkati lakumbuyo, komanso minyewa yoluma ya phewa. Kutentha kwa mankhwala operekedwa kuyenera kukhala kutentha kwa chipinda.

Njira zopewera kupewa ngozi

Pakati pa gawo la anatomical, tikulimbikitsidwa kuti musinthe gawo la jekeseni. Izi zikulepheretsa kukula kwa lipodystrophy. Ndi mankhwala a insulin, muyenera kuyang'anira shuga wamagazi nthawi zonse.

Kuphatikiza pa chakuti insulin yaumunthu komanso yachibadwa imatha kupitilira, zomwe zimayambitsa hypoglycemia zitha kukhala:

1. kudumpha chakudya;
2. kusanza, kusanza;

Matenda omwe amachepetsa kufunikira kwa hormone-insulin (pituitary, pituitary, adrenal cortex, chithokomiro cha chithokomiro, matenda a impso ndi hepatic);

1. m'malo mankhwala;
2. kusintha kwa jekeseni;
3. kuchuluka zolimbitsa thupi;
4. mogwirizana ndi mankhwala ena.

Ngati insulin yaumunthu komanso ya chibadwa ingayikidwe pafupipafupi kapena kuti mulingo woyenera, hyperglycemia imatha kuchitika, zomwe zimachitika pang'onopang'ono (maola angapo kapena masiku). Hyperglycemia imatsatana ndi:

• mawonekedwe a ludzu;
• kamwa yowuma
• kukodza pafupipafupi;
• kusanza, kusanza;
• kutaya mtima;
• chizungulire
• Kuuma ndi redness khungu;
• kununkhira kwa acetone kuchokera mkamwa.

Ngati chithandizo cha panthawi yake cha hyperglycemia sichingatheke ndi matenda a mtundu woyamba, matenda oopsa kwambiri a matenda ashuga, ketoacidosis, amatha.

Mu matenda a Addison, chithokomiro choperewera, chiwindi ndi impso, hypopituitarism ndi matenda osokoneza bongo okalamba, ndikofunikira kusintha mankhwalawa ndikuwunikira insulin yaumunthu komanso yachilengedwe.

Kusintha kwa mlingo kumafunikanso ngati wodwala asintha zakudya zomwe amakonda kapena kuwonjezera mphamvu zolimbitsa thupi.

Insulin yaumunthu komanso yachilengedwe yomwe imapanga ma insulin imachepetsa kulolera kwa mowa. Pokhudzana ndi kusintha kwa mtundu wa insulin, cholinga chake chachikulu, pali kuthekera kwakukulu kotsika kwa kuthekera koyendetsa magalimoto kapena kuwongolera njira zosiyanasiyana.

Phunziro silikulimbikitsidwa pazinthu zina zowopsa zomwe zimafuna kuti munthu azikhala ndi chidwi komanso kuthamanga kwa magalimoto ndi malingaliro.

Mtengo

Mitengo ya Isofan ku pharmacies aku Moscow imachokera ku ruble 500 mpaka 1200, kutengera mlingo ndi wopanga.