PROTAFAN INSULIN: KUFOTOKOZERA, MALINGALIRO, MTENGO

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Protafan insulini amatanthauza insulin ya anthu wamba.

Kufunika kugwiritsa ntchito mankhwala a Insulin Protafan NM penfill kumatha kuchitika ndi matenda osiyanasiyana. Choyamba, ndi matenda amtundu wa 1 ndi mtundu 2. Kuphatikiza apo, mankhwalawa akuwonetsedwa pa siteji yokana mankhwala oyamba a hypoglycemic.

Mankhwalawa amagwiritsidwanso ntchito pamodzi ndi mankhwala ophatikizika (kusungidwa kwina kwa mankhwala a hypoglycemic), ngati matenda a shuga apezeka mwa amayi apakati ndipo ngati chithandizo cha zakudya sichithandiza;

Matenda apakati ndi othandizira kuchitapo kanthu (ophatikizidwa kapena monotherapy) amathanso kukhala chifukwa choikidwiratu.

Ndingatani kuti ndithane ndi mankhwalawo, ma analogues

Insulin Bazal (mtengo pafupifupi 1435 rubles);
Humulin NPH (mtengo pafupifupi ruble 245);
Protafan NM (mtengo pafupifupi 408 ma ruble);
Aktrafan NM (mtengo pafupifupi
Protafan NM Penfill (mtengo pafupifupi ruble 865).

Zolemba za mankhwala

Mankhwala ndi kuyimitsidwa komwe kumayambitsidwa pansi pa khungu.

Gulu, ntchito:

Isulin insulin-human semisynthetis (semisynthetisita wa anthu). Ili ndi nthawi yayitali yochitapo kanthu. Protafan NM imaphatikizidwa mu: insulinoma, hypoglycemia ndi hypersensitivity pazomwe zimagwira.

Kodi mutenge ndi kumwa motani?

Insulin imalowetsedwa kamodzi kapena kawiri patsiku, theka la ola musanadye chakudya cham'mawa. Pamalo ano, momwe majekeseni amapangidwira, ayenera kusinthidwa nthawi zonse.

Mlingo uyenera kusankhidwa kwa wodwala aliyense payekhapayekha. Kuchuluka kwake kumadalira kuchuluka kwa shuga mumkodzo ndi magazi, komanso machitidwe a matendawa. Kwenikweni, mlingo umayikidwa 1 nthawi patsiku ndipo ndi 8-24 IU.

Mu ana ndi akulu omwe ali ndi hypersensitivity kwa insulin, kuchuluka kwa mlingo kumachepetsedwa mpaka 8 IU patsiku. Ndipo kwa odwala omwe ali ndi vuto lotsika, madokotala omwe akupezekapo amatha kukupatsani mankhwala okwanira 24 IU patsiku. Ngati mlingo wa tsiku ndi tsiku umaposa 0,6 IU pa kg, ndiye kuti mankhwalawa amaperekedwa ndi jakisoni awiri, omwe amachitika m'malo osiyanasiyana.

Odwala omwe amalandira 100 IU kapena kuposerapo patsiku, amasintha insulin, ayenera kuyang'aniridwa ndi madokotala nthawi zonse. Kusintha mankhwalawo ndi kwina kuyenera kuchitika ndikuwunikira kuchuluka kwa shuga m'magazi.

Mankhwala

Malo a Insulin Protafan:

amachepetsa shuga m'magazi;
bwino mayamwidwe a shuga mu minofu;
amathandizira pakupanga mapuloteni osintha;
amachepetsa kuchuluka kwa shuga m'magazi;
kumapangitsa glycogenogeneis;
Amachita bwino mauxos.

Microinteraction ndi ma receptors kumtundu wakunja kwa cell imalimbikitsa kupangidwe kwa insulin receptor tata. Mwakukondoweza mu maselo a chiwindi ndi maselo amafuta, kaphatikizidwe ka CAMP kapena kulowa m'misempha kapena khungu, insulin receptor tata imayambitsa zomwe zimachitika mkati mwa maselo.

Zimayambanso kaphatikizidwe kazinthu zina zazikulu za michere (glycogen synthetase, hexokinase, pyruvate kinase, ndi zina).

Kutsika kwa shuga m'magazi kumayambitsidwa ndi:

kuchuluka kwa shuga m'magazi;
kukondoweza kwa glycogenogeneis ndi lipogeneis;
kuchuluka mayamwidwe ndi glucose wa minofu;
mapuloteni kaphatikizidwe;
kutsika kwa kuchuluka kwa shuga omwe amapangidwa ndi chiwindi, i.e. kuchepa kwa kuwonongeka kwa glycogen ndi zina.

Kodi mankhwalawa amabwera liti ndipo amatenga nthawi yayitali bwanji?

Atangoyambitsa kuyimitsidwa atapangidwa, zotsatira zake sizichitika. Amayamba kuchita mphindi 60 - 90.

Kuchuluka kwake kumachitika pakati pa maola 4 ndi 12. Kutalika kwa zochita ndikuchokera kwa maola 11 mpaka 24 - zonse zimatengera mlingo ndi kuphatikizidwa kwa insulin.

Zotsatira zoyipa

Hypoglycemia (mawonekedwe amisala ndi kuyankhula, kutsekeka kwa khungu, kusunthika kwakasunthidwe, kuchuluka kwa thukuta, zachilendo, kulumikizana, kupsinjika, kupsinjika, kukhumudwa, kuchuluka kwa mantha, mantha, kusowa tulo, kuda nkhawa, kugona, kugona kwa pakamwa. ;

Thupi lawo siligwirizana (kuchepa magazi, urticaria, kupuma movutikira, malungo, angioedema);

Kuwonjezeka kwa gawo la anti-insulin antibodies ndikuwonjezereka kwa glycemia;

Diabetesic acidosis ndi hyperglycemia (motsutsana ndi matenda ndi kutentha thupi, kusowa kwa chakudya, jakisoni wochepa, milingo yocheperako): nkhope ikuwonetsa, kugona, kusowa chilala, ludzu losatha;

Hypoglycemic chikomokere;

Pa gawo loyambirira la zamankhwala - zolakwika zolimbitsa thupi ndi edema (chinthu chosakhalitsa chomwe chimachitika ndi chithandizo chinanso);

Kusokonezeka kwa chikumbumtima (nthawi zina kumakhala kukomoka komanso mawonekedwe a precomatose);

Pa malo a jakisoni, kuyabwa, hyperemia, lipodystrophy (hypertrophy kapena atrophy ya subcutaneous mafuta);

Kumayambiriro kwa chithandizo chamankhwala chimakhala chosakhalitsa;

Kuphatikizana kwa zamankhwala ndi insulin yaumunthu.

Zizindikiro za bongo:

kukokana
thukuta;
hypoglycemic chikomokere;
palpitations
kusowa tulo
kusawona bwino ndi kuyankhula;
kugwedezeka
mayendedwe osokonekera;
kugona
kulakalaka;
machitidwe achilendo;
Kuda nkhawa
kusakhazikika
paresthesia pamlomo wamkamwa;
Kukhumudwa
womvera
mantha
mutu.

Kodi kuchitira bongo?

Ngati wodwalayo ali ndi vuto lakelo, ndiye kuti dokotala amakupatsani mankhwala a dextrose, omwe amaperekedwa kudzera mwa dontho la magazi, kudzera m'mitsempha kapena m'mitsetse. Glucagon kapena hypertonic dextrose solution imayendetsedwanso kudzera m'mitsempha.

Pankhani ya kukomoka kwa hypoglycemic, 20 mpaka 40 ml, i.e. 40% dextrose solution kufikira wodwala atatuluka chikomokere.

Malangizo ofunikira:

Musanatenge insulini phukusi, muyenera kuwona kuti yankho mu botolo ili ndi mtundu wowonekera. Ngati kusefukira, matenthedwe kapena matupi akunja kumaonekera, yankho limaletsedwa.
Kutentha kwa mankhwala musanakhazikitsidwe kuyenera kukhala kutentha kwa chipinda.
Pamaso pa matenda opatsirana, kuvuta kwa chithokomiro, matenda a Addiosn, kulephera kwa impso, hypopituitarism, komanso odwala matenda ashuga okalamba, mlingo wa insulin umayenera kusinthidwa payekhapayekha.

Zomwe zimayambitsa hypoglycemia zitha kukhala:

bongo
kusanza
kusintha kwa mankhwala;
matenda omwe amachepetsa kufunika kwa insulin (matenda a chiwindi ndi impso, hypofunction ya chithokomiro, pituitary gland, adrenal cortex);
osagwirizana ndi kudya;
mogwirizana ndi mankhwala ena;
kutsegula m'mimba
kuchuluka kwa thupi;
kusintha kwa jekeseni.

Mukasamutsa wodwala kuchokera ku insulin ya nyama kupita ku insulin ya anthu, kuchepa kwa shuga m'magazi kungaoneke. Kusintha kwa insulin yaumunthu kuyenera kuvomerezedwa kuchokera ku malingaliro azachipatala, ndipo akuyenera kuchitika moyang'aniridwa ndi dokotala.

Nthawi yobadwa komanso yobereka, kufunika kwa insulini kumatha kuchepetsedwa kwambiri. Pa mkaka wa m`mawere, muyenera kuwunika amayi anu kwa miyezi ingapo, mpaka kufunika kwa insulin kukhazikika.

Kuwona kwa kupitirira kwa hypoglycemia kungayambitse kuwonongeka kwa wodwala kuyendetsa magalimoto ndikusunga makina ndi makina.

Pogwiritsa ntchito shuga kapena zakudya zamafuta ambiri, odwala matenda ashuga amatha kuyimitsa mtundu wofatsa wa hypoglycemia. Ndikofunika kuti wodwalayo nthawi zonse amakhala naye 20 g shuga.

Ngati hypoglycemia yakhazikitsidwa, ndikofunikira kudziwitsa dokotala yemwe apange chithandizo.