Amoxiclav ndi mankhwala otchuka omwe amapatsidwa matenda osiyanasiyana omwe amaperekedwa ndi microflora ya pathogenic. Nthawi zina, mankhwalawa sangathe kumwa chifukwa cha contraindication. Kuphatikiza apo, pali chiopsezo cha mavuto, choncho funsanani ndi katswiri musanayambe chithandizo.
ATX
Mankhwalawa adamupatsa dzina loti J01CR02. Zikutanthauza kuti mankhwala opangira mankhwala, malinga ndi gulu la anatomical komanso achire, ndi mankhwala antimicrobial. Kugwiritsa kwake mwadongosolo kumaloledwa. Ndi ya beta-lactams. Ndilo gulu la penicillin. Mulinso kuphatikiza ndi zinthu zomwe zimapondereza beta-lactamases.
Amoxiclav ndi mankhwala otchuka omwe amapatsidwa matenda osiyanasiyana omwe amaperekedwa ndi microflora ya pathogenic.
Kutulutsa mawonekedwe ndi kapangidwe ka Amoxiclav
Mankhwalawa ali ndi mawonekedwe osiyanasiyana. Muli zinthu zazikulu ziwiri: amoxicillin ndi clavulanic acid. Gawo lomaliza limathandizira kukulitsa mawonekedwe awonetsedwe wa antiotic. Clavulanic acid amaletsa kumasulidwa kwa beta-lactamases, omwe amalepheretsa amoxicillin. Ndikothekanso kugwiritsa ntchito Amoxiclav motsutsana ndi mabakiteriya okhala ndi tizilombo toyambitsa matenda ambiri.
Mankhwala amagulitsidwa monga mapiritsi amwambo ndi apapo, ufa kuyimitsidwa ndi jakisoni.
Mapiritsi
Mapiritsi a Amoxiclav amabwera mumagulu osiyanasiyana. Kuchuluka kwa clavulanic acid (125 mg) kumakhala kosamalidwa nthawi zonse. Amoxicillin ndi 250 mg, 500 mg kapena 875 mg. Makapisozi amaikidwa mumaphukusi apadera ndi makatoni.
Ufa
Zomwe zili mumiyeso ya mpunga ndizophatikiza ndi 125 mg, 250 mg kapena 400 mg pazomwe zimagwira. Clavulanic acid mu mawonekedwe a potaziyamu anaphatikizidwa m'magawo ang'ono: 31.25 mg, 62.5 mg, 57 mg. Kapangidwe kake kamene kamayimitsidwa kamakhala ndi chikasu choyera. Yankho la jakisoni lili ndi 500 mg kapena 1000 mg ya amoxicillin ndi 100 kapena 200 mg wa potaziyamu clavulanate.
Njira yamachitidwe
Mankhwala a penicillin amalepheretsa michere kuphatikizika kwa pepdidoglycan. Izi ndi mapuloteni apadera omwe amachititsa kuti nembanemba ya bakiteriya ikhale yolimba. Chifukwa chodziwikirana ndi Amoxiclav, makoma a tizilombo ting'onoting'ono amawonongeka, tizilomboti timaphedwa.
Komabe, ena oimira ma gram-positive ndi gram-microflora omwe amapanga beta-lactamases. Zinthu izi zimamanga zigawo za penicillin, zosokoneza ndi achire. Mu Amoxiclav, ntchito yotsutsana imachitika ndi clavulanic acid. Imalepheretsa beta-lactamases, kukulitsa mphamvu zakuchiritsira za antibayotiki.
Pharmacokinetics
Zigawo zogwira ntchito za mankhwalawa zimatengeka mosavuta kuchokera m'matumbo am'mimba ndikulowetsa zigawo zam'magazi, minofu ndi maselo amthupi. 70% ya zinthu zofunikira zimapezeka pakatha mphindi 60 mutamwa mankhwalawa.
Excretion wa Amoxicillin amapezeka kudzera kwamikodzo dongosolo. Clavulanic acid yawonongeka m'chiwindi, impso ndi matumbo. Gawo lake limapukusidwa mu mkodzo ndi ndowe.
Zizindikiro zogwiritsidwa ntchito
Wothandizira antibacterial amagwiritsidwa ntchito kuti athetse tizilombo tating'onoting'ono tomwe timayambitsa matenda. Mndandanda wazidziwitso ukuphatikizapo:
- matenda kupuma (pharyngitis, tonsillitis, bronchitis, chibayo, abscess ya mmero ndi pharynx, tonsillitis, sinusitis, sinusitis, kutsogolo sinusitis);
- njira zopatsirana ndi zotupa mu kwamkodzo thirakiti ndi kubereka (cystitis, urethritis, cervicitis, endometritis, prostatitis);
- matenda a pakhungu ndi pafupi;
- kuwonongeka kwa minofu ndi mafupa omwe amakwiya ndi tizilombo toyambitsa matenda;
- matenda a biliary thirakiti (cholengitis, cholecystitis);
- kupewa ndi kuchiza mavuto pambuyo pa opaleshoni.
Mankhwalawa amalembedwa ndi katswiri pambuyo pa mayeso onse ofunikira komanso kumveketsa chidwi cha maselo a pathogenic kuti amoxicillin.
Contraindication
Maantibayotiki sayenera kumwedwa makamaka ndi vuto la penicillin kapena cephalosporins. Contraindication ndi pachimake kapena matenda aimpso, kuwonongeka kwa chiwindi, kukokoloka kwa njira m'matumbo a ziwalo ndi biliary thirakiti.
Mankhwalawa samaperekedwa m'mabotolo kwa odwala ochepera zaka 12 wazakudya zosakwana 40 kg.
Mankhwalawa amaletsedwa matenda opatsirana a mononucleosis ndi pathologies a metabolism. Kusamala ndikofunikira kugwiritsa ntchito mankhwalawa podikirira mwana komanso ndi HB.
Momwe mungamwe mankhwalawa
Njira yotengera antibacterial wothandizila imatengera mtundu wa kumasulidwa. Mapiritsi ndi kuyimitsidwa adapangidwa kuti agwiritsidwe ntchito mkati, ufa wopangira njira yothandizira jekeseni imagwiritsidwa ntchito kudzera m'mitsetse. Mlingo komanso nthawi yayitali ya mankhwalawa imatsimikiziridwa ndi dokotala kutengera mawonekedwe a matendawa, zaka komanso thanzi la wodwalayo.
Kwa matenda osavuta, achikulire ndi achinyamata omwe akulemera makilogalamu oposa 40 amalangizidwa kumwa piritsi limodzi lokhala ndi 250 mg ya amoxicillin ndi 125 mg ya clavulanic acid, katatu patsiku. Mankhwalawa amatengedwa maola asanu ndi atatu alionse. Odwala kwambiri m'matenda a kupuma, mlingo wa 500/125 (625) mg katatu patsiku kapena 875/125 mg 2 kawiri mu maola 24 ayenera kumwedwa. Kutalika kwa maphunzirowa kumatsimikiziridwa ndi adokotala. Koma siziyenera kupitirira milungu iwiri.
Ngati Amoxiclav amalembera mwana wochepera zaka 12, ndiye kuti amaloledwa kupereka madzi.
Ngati Amoxiclav amalembera mwana wochepera zaka 12, ndiye kuti amaloledwa kupereka madzi. Mlingo umatengera kulemera kwa thupi komanso msinkhu wa mwana. Jekeseni wa akulu ndi ana a zaka 12 amaikidwa mu chipatala ngati gawo la zovuta zochizira matenda opweteka a ziwalo zamkati.
Musanadye kapena musanadye
Makapu a Amoxiclav tikulimbikitsidwa kuti atenge ndi chakudya kuti muchepetse zotsatira zoyipa m'mimba. Kudya munthawi yomweyo sikukhudza mayamwidwe ndi kuchiritsa kwa zomwe zimagwira.
Zotsatira zoyipa
Maantibayotiki amatha kupangitsa kuti thupi lizituluka. Pazizindikiro zoyambirira za zoyipa, muyenera kudziwitsa dokotala za zizindikirozo, ndipo ngati kuli koyenera, lekani kumwa mankhwalawo.
Kuchokera kwamikodzo
Zotsatira zoyipa za mankhwala othandizira kwamikodzo ndizosowa ndipo zimawonekera pakupanga interstitial nephritis, crystalluria ndi hematuria.
Kuchokera ku dongosolo lamanjenje lamkati
Anthu ali ndi mutu, nkhawa, kusowa tulo, kusintha kwa machitidwe. Nthawi zina, anthu amakomoka. Nthawi zambiri, zotsatira zoyipa izi zimawonekera mwa anthu omwe ali ndi vuto la a impso.
Kuchokera m'mimba
Mukamamwa Amoxiclav, munthu amadwala, nthawi zambiri pamakhala kusanza kapena kutsegula m'mimba. Zizindikiro izi zitha kupewedwa ngati mugwiritsa ntchito mankhwalawa koyambirira kwam'mawa. Zomwe zimakonda kwambiri ndi stomatitis, pseudomembranous kapena hemorrhagic colitis.
Kuchokera ku hematopoietic dongosolo ndi dongosolo la lymphatic
Mankhwalawa amasintha zizindikiro zamankhwala. Nthawi zambiri pamakhala leukopenia, thrombocytopenia, agranulocytosis kapena hemolytic anemia. Zotsatira zoyipa za hematopoietic dongosolo zimasinthidwanso ndipo zimatha mofulumira mankhwala atatha.
Thupi lawo siligwirizana
Mankhwala a penicillin amayambitsa ming'oma, kuyabwa kwa khungu, erythema ndi mawonekedwe ena osiyanasiyana am'deralo.
Malangizo apadera
Panthawi yamankhwala, tikulimbikitsidwa kuwunika kuchuluka kwa magazi, komanso kuwunika ntchito ya chiwindi, impso ndi mtima. Pamaso pa pathologies a ziwalozi, ndikofunikira kuchepetsa mlingo wa mankhwalawo kapena kusankha mtundu wina wa antiotic.
Zowopsa zomwe zimakhudzidwa ndi chidwi chochuluka cha ma penicillin sizimachotsedwa. Munthawi yonse ya mankhwalawa, muyenera kukhala ndi boma la kumwa ndikuwongolera diuresis.
Munthawi yonse ya mankhwalawa ndi Amoxiclav, muyenera kukhalabe ndi regimen.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Zomwe zimapangidwa ndi antibacterial wothandizila zimatha kudutsa zotchinga. Kafukufuku wachipatala cha nyama wasonyeza kuti zinthu zomwe zimagwira mu Amoxiclav sizimayambitsa kusokonezeka kwa fetal.
Komabe, zotsatira za mayeso athunthu okhudzana ndi amayi apakati sizikupezeka. Chifukwa chake, lingaliro la kuthekera kotenga kachiromboka pakubala mwana limapangidwa ndi adokotala, motsogozedwa ndi lamulo kuti phindu lomwe lingakhalepo kwa mayi limaposa chiwopsezo kwa mwana wosabadwayo. Zikatero, mankhwalawa amatha kutumikiridwa kuchokera 2nd trimester yokha.
Pa mkaka wa m`mawere, ngati kuli kotheka, mankhwala opha mabakiteriya a ana ayenera kuthandizidwa kupita ku zakudya zosafunikira.
Mowa sugwirizana ndi Amoxiclav. Mowa umachepetsa achire zotsatira ndikuwonjezera zoyipa. Mankhwala amachepetsa kuthamanga kwa ma psychomotor, chifukwa chake, zotsatira zoyipa poyendetsa galimoto ndi zida zina zovuta sizimalamulidwa.
Momwe mungaperekere Amoxiclav kwa ana
Kwa ana aang'ono, ufa wa kuyimitsidwa umapangidwa. Zomwe zili mu vial zimathiridwa ndi madzi owiritsa pamoto kutentha, atsekedwa ndi kugwedezedwa mpaka misa yayikulu ikapangidwa.
Kwa ana aang'ono, ufa wa kuyimitsidwa umapangidwa.
Ana kuyambira miyezi itatu amapatsidwa 20 mg / kg kawiri pa tsiku. Mlingo wa tsiku ndi tsiku sayenera kupitirira 45 mg / kg. Chithandizo chikuchitika moyang'aniridwa ndi dokotala wa ana.
Achinyamata opitirira zaka 12 ndi kulemera kuposa makilogalamu 40 amatha kumwa mapiritsi atatha kufunsa dokotala.
Bongo
Kuonjezera Mlingo wovomerezeka wa mankhwalawa kumayambitsa mseru komanso kusanza. Anthu amatha kudwala matenda a impso. Nthawi zina, kusokonezeka kumachitika, kuvuta kupuma, kusokonezeka kwa kayendedwe ka kayendedwe.
Palibe mankhwala enieni. Mu maola 4 oyambirira mukatha kumwa mankhwalawa, m'mimba mumachitika. Kaboni yokhazikitsidwa imaloledwa kuti muchepetse kuyamwa kwa zosakaniza zolimba. Ndiye amachitira mankhwala othandizira. Panalibe milandu yakupha yochokera ku bongo wa Amoxiclav.
Kuchita ndi mankhwala ena
Kuyamwa kwa antibiotic kumachepetsedwa akaphatikizidwa ndi maantacid, aminoglycosides, ndi mankhwala ofewetsa tuvi tolimba. Mankhwala osagwiritsa ntchito mahomoni oletsa kutupa komanso mankhwala a diuretic omwe amatchinga katulutsidwe ka tubular kumawonjezera ndende ya amoxicillin. Metatrexate imathandizira poizoni wake mothandizidwa ndi mankhwalawa.
Mankhwalawa sagwiritsidwa ntchito ndi ma anticoagulants chifukwa choika magazi.
Mphamvu yothandizira ya Amoxiclav imatsika akagwiritsidwa ntchito limodzi ndi macrolides, sulfonamides ndi tetracyclines.
Pochita ndi mankhwala okhala ndi mycophenolate mofetil, mwayi woti ungagawanike ndikuyankhira kwotsirizira kumachepetsedwa. Kuphatikiza kwa amoxicillin ndi clavulanic acid ndi theka kumachepetsa ndende ya mankhwala ambiri owola - mycophenolic acid.
Analogi
Zofanana ndi Amoxiclav pazinthu zazikulu ndi Augmentin. Ku Switzerland, kutulutsidwa kwa Amoxiclav Quiktab, komwe kumakhala kofanana, kwakhazikitsidwa kalekale. Sumamed ali pafupi ndi maantibayotiki potengera njira yochizira komanso momwe amagwirira ntchito pama cell mabakiteriya. Ndi m'gulu la macrolide. Komabe, yogwira mankhwala azithromycin imakhala ndi zochita zambiri.
Kupita kwina mankhwala
Ndi mankhwala. Chikalatachi chimadzazidwa mchilatini chikuwonetsa kuchuluka kwa zosakaniza zomwe zikugwira. Kuphatikiza apo, ndikofunikira kuwonetsa dzina lazamalonda kuti wopanga mankhwalawa apereke mankhwala omwe akufuna, osati chiwonetsero chake.
Kodi ndingagule popanda kulandira mankhwala?
Maantibiotic sangatengedwe popanda kufunsa dokotala, chifukwa chake ndizosatheka kugula mankhwala popanda mankhwala.
Mtengo wa Amoxiclav
Mtengo wa mankhwalawa umatengera wopanga, mtundu wa kumasulidwa ndi mlingo.
Mtengo wapakati umachokera ku ma ruble 120 (mapiritsi) mpaka ma ruble 850 (ufa womwe njira yothetsera jakisoni umapangidwira).
Zosungidwa zamankhwala
Mankhwalawa amasungidwa kuchokera kwa ana. Ndikofunikira kuti kutentha kwa chipindacho kusungidwe pamalo osungirako, chinyezi chikuluzikulu komanso kuyatsidwa kwa dzuwa mwachindunji pokonzekera sikuyenera kuloledwa. Kuyimitsa komwe kumalizidwa kuyenera kusungidwa mufiriji.
Ndikofunikira kuti kutentha kwa chipinda kusungidwe pamalo osungiramo mankhwala.
Alumali moyo wa mankhwala Amoxiclav
Zaka 2 Poda yovunda iyenera kugwiritsidwa ntchito pakatha sabata limodzi.
Ndemanga za madotolo ndi odwala pa Amoxiclav
Yaroslav, wazaka 46, Magnitogorsk
Mankhwala otsika mtengo opatsirana opatsirana opumira kwambiri. Muzochita zanga zamankhwala, ndimakonda kuzilemba kwa odwala omwe ali ndi mbiri ya matenda osachiritsika, chifukwa mankhwalawo ndi otetezeka momwe angathere.
Elizabeth, wazaka 30, Gatchina
Zonsezi zinkayamba ngati chimfine. Pambuyo pa sabata, zizindikirazo sizinachoke, kusokonezeka kwammphuno kunawonekera, kutentha pang'ono kumasungidwa. The otolaryngologist adagwiritsa ntchito mankhwalawa pa mlingo wa 500/25 mg kawiri pa tsiku. Patatha masiku ena asanu, ntchofu wobiriwira wonyezimira unkatuluka kuchokera pamphuno, pomwe panali chifuwa champhamvu. Zinapezeka kuti maantibayotiki pamtengowu alibe ntchito. Sinusitis yayikulu ndi kutsogola sinusitis Ndinasinthira kukhala mankhwala amphamvu. Ndikuganiza kuti mapiritsiwa ndiwachikale komanso osathandiza, ndikudandaula kuti ndidawononga nthawi ndi thanzi.
Arina, wazaka 28, Chelyabinsk
Odwala zilonda zaposachedwa. Vutoli linali loopsa: kutentha thupi kwambiri, zilonda zapakhosi, migraine komanso kufooka. Panalibe mphamvu zochoka pabedi. Adokotala adaitanidwa kunyumba. Kupulumutsidwa ndi Amoksiklav. Ndiotsika mtengo, imalimbana ndi matenda. Palibe mavuto. Ndine wokondwa ndi chida ichi.
