Anthu omwe ali ndi matenda a shuga a mtundu wachiwiri sakhala okhazikika nthawi zonse azikhala ndi glucose malinga ndi zakudya komanso masewera olimbitsa thupi. Chifukwa chake, odwala matenda ashuga ena amagwiritsa ntchito othandizira a hypoglycemic, makamaka Glidiab.
Mankhwalawa amathandizira kukhazikika pamlingo wa shuga m'magazi, ndikuwonjezera mphamvu ya chithandizo chamankhwala ngati wodwala matenda ashuga akudwala kunenepa kwambiri. Komanso, mukamagwiritsa ntchito Glidiab MV 30, nsonga ya insulin secretion imabwezeretseka.
Kodi ndingagule bwanji mankhwala a Glidiab? Mu mankhwala, mtengo wa mankhwala ndi ma ruble a 120-200. Mtengo wake umadalira kuchuluka kwa mankhwala opangira piritsi. Glidiab MB 30 mg ndi 80 mg amapezeka pamsika.
Njira yamachitidwe ndikuwonetsa ntchito
Glidiab MV ndi wothandizira waogoglycemic wa gulu la sulfonylurea zotumphukira za m'badwo wachiwiri. Mankhwalawa amakhala ndi gliclazide ndi okondwerera. Glyclazide piritsi limodzi lili ndi 80 mg kapena 30 mg.
Kodi chigawo chogwira ntchito cha mankhwalawo chimagwira ntchito bwanji? Glyclazide pa mayamwidwe imalimbikitsa minofu glycogen synthetase ntchito ndi insulin katulutsidwe. Komanso, chinthu ichi chimapangitsa insulini mwachinsinsi kukula kwa glucose, ndikuthandizira kuwonjezeka kwamphamvu ya zotumphukira za insulin.
Kuphatikiza apo, gliclazide imathandizira kuchepetsa kusiyana pakati pa kudya ndi kuyambika kwa gawo lobisika la insulin. Ngati mungayang'ane malangizo omwe mungagwiritse ntchito Glidiab, mutha kudziwa kuti mukamagwiritsa ntchito mapiritsi, kuchuluka kwa hyperglycemia kumachepa, ndipo nsonga yoyambirira ya insulin secretion imabwezeretseka.
Zinthu zonsezi zimakhudza kagayidwe kazakudya ndi michere. Ngati mukukhulupirira malangizowo, ndiye kuti Glidiab MV amathandizira kuchepetsa kuphatikizika ndi kuphatikizika kwa mapulateleti, komanso munthawi yomweyo kusintha kukokoloka kwa mtima. Mwachidule, pogwiritsa ntchito mapiritsi, mwayi wopitilira muyeso wa microthrombosis ndi atherosulinosis umachepetsedwa kwambiri.
Kafukufuku adawonekanso kuti wothandizira wa hypoglycemic amathandizira kuchepetsedwa kwa zovuta monga matenda ashuga retinopathy pamalo osapindika. Kuphatikiza apo, kugwiritsa ntchito mapiritsi a Glidiab MV kungakulitse kwambiri mphamvu ya mankhwala othandizira odwala omwe ali ndi kunenepa kwambiri.
Ndikufuna kudziwa kuti ma metabolites a mankhwalawa amachotsedwa pamodzi ndi mkodzo m'njira yosasinthika, komanso palinso ndowe mu mawonekedwe a metabolites.
Malangizo ogwiritsira ntchito mankhwalawa
Ndi munthawi ziti zomwe zikuyenera kugwiritsidwa ntchito mapiritsi a Glidiab 80? Malangizowo akunena kuti ndikofunikira kugwiritsa ntchito mankhwalawa mankhwalawa mtundu wa 2 matenda a shuga, ngati mankhwala othandizira pakudya ndi masewera olimbitsa thupi sizithandiza kukhazikika kwa shuga.
Molumikizana ndi mankhwala ena, Glidiab MB sigwiritsidwa ntchito kwambiri. Koma ziyenera kudziwika kuti zotsatira za hypoglycemic za mankhwalawa zitha kuchuluka ngati, limodzi ndi mankhwala osokoneza bongo, kudya ndikusewera masewera ndizoyenera.
Momwe mungamwere mankhwala? Mlingo woyambirira ndi 80 mg. Komanso, pafupipafupi kugwiritsa ntchito ndi 2 kawiri pa tsiku - m'mawa ndi madzulo. Ndi bwino kumwa mapiritsi 30-60 mphindi musanadye.
Ngati mulingo wocheperako wa 80 mg ulibe hypoglycemic, ndiye kuti mwapang'onopang'ono kuchuluka kwake. Nthawi zambiri, pamatenda a shuga a 2, mlingo wa 160 mg ndi wokwanira. Mlingo woyenera wovomerezeka wa mankhwalawa ndi 320 mg.
Koma tiyenera kukumbukira kuti ndi kuchuluka kwa Mlingo, mwayi wopita patsogolo wa hypoglycemia ndi zovuta zina kumakula kwambiri.
Kuyanjana Ndi Mankhwala Osokoneza Ubwenzi
Tiyenera kukumbukira kuti mankhwalawa amatha kuonjezera mphamvu ya hypoglycemic ya mankhwala a Glidiab MB. Chifukwa chake, malangizowo amanenanso kuti mankhwalawa amayenera kuphatikizidwa mosamala kwambiri ndi histamine H2-receptor blockers, mankhwala osokoneza bongo a anti-yotupa, othandizira antifungal, ACE inhibitors.
Mankhwala ochepetsa chifuwa, ma beta-adrenoblockers, anticoagulants osadziwika, anabolic steroids, Mao inhibitors, salicylates ndi ena amathanso kukulitsa zotsatira za hypoglycemic.
Ichi ndichifukwa chake musanagwiritse ntchito mapiritsi a Glidiab, muyenera kuphunzira mosamala malangizo ndikuwonana ndi dokotala.
Mwa contraindication kugwiritsa ntchito mapiritsi angadziwike:
- Matenda a shuga a Mtundu woyamba amadalira insulin.
- Matenda a shuga ketoacidosis.
- Zabwino kapena zaphokoso. Kuphatikiza apo, kuponderezana kokhazikika ndi hyperosmolar coma.
- Leukopenia
- Nthawi yapakati.
- Nthawi yonyamula.
- Kwambiri kwamtundu wa hepatic ndi aimpso.
- Mikhalidwe yomwe imayendetsedwa ndi kuphwanya dongosolo la mayamwidwe akudya, komanso kukula kwa hypoglycemia. Zinthu zoterezi zimaphatikizira matumbo, kutsekeka kwa m'mimba komanso matenda opatsirana.
- Chiwopsezo kwa zigawo za mapiritsi.
- Mikhalidwe yomwe insulin mankhwala ingafunikire. Izi zimaphatikizapo kupsa, kuvulala, kapena opaleshoni.
- Mowa
- Febrile syndrome.
Komanso, mankhwalawa ayenera kugwiritsidwa ntchito mosamala kwa anthu omwe ali ndi vuto la chithokomiro.
Ndemanga ndi zoyipa za Glidiab
Ndi ndemanga ziti za Glidiab? Anthu odwala matenda ashuga amayankha bwino mankhwalawo. Anthu ambiri amakopeka ndi mtengo wotsika mtengo wa mankhwalawo, komanso zizindikiro zapamwamba zogwira ntchito.
Komanso, Glidiab, malinga ndi odwala matenda ashuga, ndiabwino chifukwa samayambitsa zotsatira zoyipa pamankhwala ochepa. Chikhalidwe china cha mankhwalawa kwa anthu ndikuti zimawonjezera mphamvu ya mankhwala othandizira kudya.
Zotsatira zoyipa zomwe mankhwala a hypoglycemic angayambitse? Malinga ndi malangizo, mankhwalawa angayambitse:
- Kuphwanya kwa endocrine dongosolo. Amawoneka ngati hypoglycemia. Koma dziwani kuti kuphatikiza uku kumachitika pokhapokha ngati pali mankhwala osankhidwa bwino.
- Kukwiya, kugona, kuzunzidwa, kunjenjemera miyendo, mutu, chizungulire, kutopa kwambiri.
- Kuchepetsa maonedwe owoneka.
- Aphasia.
- Bradycardia
- Kupuma kosapumira.
- Delirium.
- Thrombocytopenia, kuchepa magazi, leukopenia.
- Thupi lawo siligwirizana.
- Matumbo dongosolo. Munthu amatha kudwala matenda otsekula m'mimba, kumva kupsinjika kwa dera la epigastric, nseru, matenda anorexia, cholestatic jaundice, kuchuluka kwa hepatic transaminases.
Nthawi zambiri, mavuto amadzisinthira atasiya kumwa mankhwalawo ndikulandira chithandizo choyenera.
Analogue yabwino kwambiri ya Glidiab
Kodi ma fanizo a Glidiab ndi ati? M'malo mwake, othandizira osiyanasiyana a hypoglycemic malinga ndi metformin hydrochloride angagwiritsidwe ntchito. Analog yamagulu othandiza kwambiri ndi Fomu. Mankhwalawa ndiye malo abwino kwambiri a Glidiab.
Mtengo wa mankhwalawa ndi pafupifupi ma ruble a 180-260. Formetin imapezeka mu Mlingo wa 500 mg, 850 mg ndi 1 gramu. Phukusi limodzi lili ndi mapiritsi 60. Kuphatikizika kwa mankhwalawa kumaphatikizapo metformin hydrochloride, povidone, primellose, magnesium stearate.
Kodi chigawo chogwira ntchito cha formin chimagwira bwanji? Malangizowo akuwonetsa kuti metformin hydrochloride imalepheretsa gluconeogeneis m'chiwindi, komanso amathandizira kuchepetsa kuyamwa kwa glucose kuchokera m'matumbo.
Komanso, gawo lokhazikika limathandizira kugwiritsidwa ntchito kwina kwa glucose, ndikuthandizira kukulitsa chidwi cha minofu pazovuta za insulin. Pankhaniyi, metformin hydrochloride siyikhudzanso njira ya insulin yobisalira ndi maselo a beta, chifukwa chomwe imapangitsa kuchepa kwa hypoglycemia.
Mothandizidwa ndi Formetin, a 2 matenda a shuga amatha kuthandizidwa. Makamaka, mankhwalawa amagwiritsidwa ntchito ngati wodwala matenda ashuga atha kunenepa kwambiri komanso ngati chithandizo cha zakudya sichithandiza kuteteza matenda a shuga. Ndikufuna kudziwa kuti mankhwalawa nthawi zambiri amagwiritsidwa ntchito molumikizana ndi mankhwala okhudzana ndi sulfonylurea.
Momwe mungapangire formin? Mlingo woyambirira ndi 1000-1700 mg patsiku. Komanso, mulingo womwewo mumagawo awiri. Ndikwabwino kumwa mapilitsi mukatha kudya ndi madzi ambiri.
Ngati shuga m'magazi sakhazikika, ndiye kuti mwapang'onopang'ono mankhwalawa amawonjezeka mpaka magalamu 2-3 patsiku. Mulingo wovomerezeka watsiku lililonse wa Formetin ndi magalamu atatu, osapitilira apo. Koma odwala okalamba amalimbikitsidwa kudya zosaposa gramu imodzi patsiku.
Zotsatira zosagwiritsidwa ntchito ndi mankhwalawa:
- Ziwengo kwa zigawo zikuluzikulu.
- Matenda a impso, makamaka kulephera kwa aimpso.
- The pachimake gawo la myocardial infarction.
- Kuthetsa madzi m'thupi.
- Mtima kapena kulephera kupuma.
- Cerebrovascular ngozi.
- Uchidakwa wambiri
- Mimba komanso kuyamwa.
- Zomwe zimafunikira pakugwiritsa ntchito insulin. Zimatha kuvulala kwambiri, kuwotcha kapena kuchitapo kanthu opaleshoni.
- Lactic acidosis.
- Kutsatira zakudya zamagulu, zomwe zimapereka kuchepa kwa zopatsa mphamvu za tsiku ndi tsiku mpaka ma kilocalories a 1000.
- Ntchito masiku 2 omaliza a x-ray maphunziro ndi kuyambitsa kusiyanasiyana kwa ayodini. Mwa njira, mankhwalawa sayenera kumwa masiku awiri 2 musanakumane ndi X-ray.
Mwa zina zoyipa za mankhwalawa, pali zovuta m'magayidwe am'mimba, kusokonezeka kwa metabolic, kuchepa kwa magazi, kuchepa kwa magazi ndi matendawo. Kanemayo munkhaniyi akuwuzani zamankhwala omwe ali ndi matenda ashuga.